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Nonclinical Similarity of the Biosimilar Candidate ABP 938 with Aflibercept Reference Product
Published 2024-11-01“…Abstract Introduction ABP 938 is being developed as a biosimilar to Eylea® (aflibercept reference product [RP]), an anti-vascular endothelial growth factor (VEGF) drug used in the management of retinal diseases. Previously, a comparative analytical similarity assessment demonstrated that ABP 938 and aflibercept RP have the same amino acid sequence and exhibit similar higher-order structure and biological activity. …”
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Allometric equations for estimating above and belowground biomass of Colophospermum mopane in Mozambique
Published 2025-01-01“…This research is timely as there is an urgent need to improve the accuracy of carbon counting to support climate change goals and sustainable management of Mopane woodland given their spatial extent in southern Africa.…”
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Carbon Nanomaterials in the Treatment of Infectious Bone Defects and Wound Scars after Wushu Fractures
Published 2020-01-01Get full text
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48325
Machine learning-based prediction of hemodynamic parameters in left coronary artery bifurcation: A CFD approach
Published 2025-01-01“…The ability to efficiently predict hemodynamic parameters could significantly aid medical practitioners in time-sensitive clinical settings, offering valuable insights for coronary artery disease management. Further research is warranted to evaluate the effectiveness of deep learning models and address challenges in patient-specific applications.…”
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Application of Transcranial Magnetic Stimulation to Improve Upper Limb Motor Function Following Cerebral Infarction: A Clinical Case Analysis
Published 2024-12-01“…Cerebral infarction, a form of acute cerebrovascular disorder affecting the brain or spinal cord, presents with focal neurological symptoms that persist for more than 24 hours post-onset. Managing complications arising from cerebral infarction typically involves a multifaceted and prolonged therapeutic approach. …”
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Functional outcome of distraction osteogenesis in infected nonunion of the tibia
Published 2024-04-01“…Consequently, this study aims to evaluate the healing rates in long bone nonunion fractures and examine the complications associated with the treatment device. Managing infected tibial nonunions remains a formidable task for orthopedic surgeons. …”
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Ensuring organisational and legal conditions for financing the social sector of Ukraine
Published 2023-09-01“…It has been noted that today the State system of budgetary funds management for financing social benefits remains one of the main components of the general and comprehensive social protection system of Ukraine. …”
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Modelling of control actions at the operational stage of the life cycle of roads
Published 2024-01-01“…One of the complex problems of road asset management is the lack of unified “integral” indicators of their condition, which simultaneously take into account the change in the longitudinal smoothness of the road surface, visual condition, and the general modulus of elasticity at the operational stage of the road life cycle. …”
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Sex-Based Variations in Hemato-Physiological Characteristics of Patients with Major Depressive Disorder: Clinical and Socioeconomic Insights
Published 2024-12-01“…Conclusion: The present work focuses on the challenges in classifying and managing depressive symptoms, highlighting the importance of considering sex-specific alterations. …”
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Analysis of occupational health examination results among medical radiation workers in Hangzhou City
Published 2025-01-01“…Methods: Data on medical radiological workers who underwent occupational health examinations from 2021 to 2022 were collected through the Physical Examination Information Management System of the Hangzhou Occupational Disease Prevention and Control Hospital. …”
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Diabetes Treatment with Dapagliflozin and Its Combinations: Insights from Clinical Practice
Published 2024-04-01“…Early initiation and intensification with a combination of SGLT2i and DPP4i in young T2DM patients (30–50 years) inadequately managed on metformin was highly recommended (94.58%). …”
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Thyroid Storm with Multiorgan Failure Treated with Plasmapheresis
Published 2019-01-01“…He was transferred to our hospital for further management. On arrival, TSH was <0.01 mIU/L, free T4 was >7 ng/dL and total T3 was 358 ng/dL. …”
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Investigating Light and Water Optimization for Early Seedling Establishment in Albizia lebbeck (L.) Benth
Published 2024-01-01Get full text
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