Saussurea costus alleviates ulcerative colitis by regulating the gut microbiota and improving intestinal barrier integrity by Wen-lin Pang, Wen-lin Pang, Tian-gang Li, Tian-gang Li, Yin-ying Wang, Yin-ying Wang, Li-yun Song, Li-yun Song, Li Li, Li Li, Xiao-ya Li, Xiao-ya Li, Yong Qiu, Yong Qiu, Zhong-shan Yang, Zhong-shan Yang

“…In addition, analysis of 16S rRNA gene sequencing indicated that SC reduced harmful bacterial populations, such as Proteobacteria, while simultaneously enhancing the levels of beneficial bacteria like Lactobacillus, thereby contributing to the improvement of UC pathology.ConclusionThis study highlights the therapeutic potential of SC in managing UC through its ability to attenuate inflammatory responses, restore intestinal barrier functionality, and modulate gut microbiota composition, which findings offer insights into potential strategies for advancing UC treatment.…”
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Cowpea cropping systems, traits preference and production constraints in the upper west region of Ghana: farmers' consultation and implications for breeding by Benjamin Karikari, Margaret Delle Maale, Ebenezer Anning, Daniel Brain Akakpo, Afishata Mohammed Abujaja, Isaac Kwahene Addai

“…It is also used for soil management within a cropping system. However, cowpea production is confronted with numerous challenges. …”
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Implementing university wellness program for mental wellbeing among health science students: A protocol for implementing an intervention program in higher educational institutions... by Bala Ganesh Pichamuthu, Sathya Thennavan, Sharmila Govardhanan

“…Substantial improvements in students’ mental health were observed, with reductions in anxiety, depression, and stress. The stress management sessions were found to be beneficial by 80% of students, while life skills training and recreational clubs received high participation rates and positive feedback. …”
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Development of a non-specialist worker delivered psychological intervention to address alcohol use disorders and psychological distress among conflict-affected populations in Ugand... by Abhijit Nadkarni, Alessandro Massazza, Wietse A. Tol, Sergiy Bogdanov, Lena S. Andersen, Quincy Moore, Bayard Roberts, Helen A. Weiss, Soumya Singh, Melissa Neuman, Carl May, Daniela C. Fuhr

“…The CHANGE intervention developed through the consultative workshops can be delivered in three sequential phases focussed on assessment, feedback, and information (Phase 1); providing the client with need-based skills for dealing with high-risk situations related to alcohol use (Phase 2), and relapse prevention and management (Phase 3). Conclusions CHANGE is a contextually relevant and potentially scalable treatment for co-existing AUD and psychological distress to be delivered by NSWs to conflict-affected populations. …”
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Fuzzy Logic Recommender Model for Housing by Emanuel G. Munoz, Jaime Meza, Sebastian Ventura

“…The recommendation system relies on fuzzy control to manage user preferences and select appropriate input data with which to test the model. …”
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Transcatheter edge to edge compared with surgery in older patients with degenerative mitral valve regurgitation by Gaspard Suc, Rebecca Hadjedj, Jules Mesnier, Skerdi Haviari, Marylou Para, Gregory Ducrocq, Dominique Himbert, Eric Brochet, My Lien Nguyen, Sophie Provenchere, Marina Urena, Bernard Iung

“…Conclusion Patients with severe primary MR treated with TEER experienced a higher rate of adverse events within one year compared to surgically managed patients. However, these differences were mainly associated to clinical characteristics and were no longer significant after adjustment on residual MR > 2. …”
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Cultural humility strategies for recruitment and retention of minoritised participants: a scoping review protocol by Mireille Chehade, Kellie McLean, Samar Mohsen Ashmawi, Moroni Fernandez Cajavilca, Baomi T Phung, Maya N Clark-Cutaia, Brynne Campbell Rice

“…The identified pool of records will be imported to Covidence, an online data management software. At the first screening stage, two independent reviewers will screen for title and abstract relevance. …”
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Integrated analysis of biochemical, transcriptomic, and metabolomic response mechanisms in Ussuri catfish (Pseudobagrus ussuriensis) under acute heat stress by Qing Liu, Yang Cao, Ruyi Hu, Libo Gu, Lirong Yang, Yu Liu, Weiwei Wang, Liang Xiao, Bugao Li

“…These findings provide valuable insights into the defense mechanisms of fish under high-temperature stress and lay a theoretical foundation for breeding heat-resistant P. ussuriensis strains, as well as improving sustainable aquaculture management.…”
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Association between alkaline phosphatase levels and mortality in Chinese patients with colorectal cancer with liver metastases: a retrospective cohort study by ZhaoXi Liu, ZiQing Zhang, GuoFang Yu, MingJiang Mo, ChuanYu Xie, DangHan Xu, JieTao Lin, YuChen Zhang, Li Deng, YiChang Luo, YingFeng Huang, Cui Shao

“…Integrating ALP measurement into clinical practice may enhance risk stratification and patient management. Future research should explore the role of ALP in broader populations and explore its implications for treatment strategies.…”
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Excessive Weight Gain During Pregnancy Increased Ponoxarase 1 Level in Neonatal Cord Blood by Serhat Ege, Hasan Akduman, Ayşegül Aşır, Tuğcan Korak

“…Maternal obesity may specifically affect PON1 activity, potentially serving as a compensatory response to oxidative stress in neonates, suggesting PON1 as a possible biomarker for oxidative stress-related metabolic disturbances in neonates of obese mothers, with implications for monitoring and managing pregnancy outcomes in obese populations.…”
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Study on the Analgesic Efficacy of Femoral Nerve Block for Post-Hip Arthroscopy Pain by Mengwen Xue, Li Zhang, Ruiping Bai, Rui An, Jiarui Li, Xin Shen

“…Abstract Introduction Postoperative pain management is challenging for hip arthroscopy, and the effectiveness and specific protocols of femoral nerve block (FNB) in hip surgeries remain insufficient. …”
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Cost–consequence analysis of COPD treatment according to NICE and GOLD recommendations compared with current clinical practice in the UK by Jennifer K Quint, Helene Vioix, Toby Capstick, Sue Langham, Jennifer Cook, Antony Wright, Shamika de Silva

“…Objectives The objective of this study was to model the clinical and economic impact of adapting current clinical practice in the management of patients with chronic obstructive pulmonary disease (COPD) to treatment according to national and international guideline recommendations.Design Treatment mapping was undertaken to hypothetically redistribute patients from current clinical practice, representing actual prescribing patterns in the UK, to an alternative recommendation-based treatment scenario, representing prescribing in accordance with either National Institute for Health and Care Excellence (NICE) guidance [NG115] or Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2020 strategy.Setting Primary care practices in the UK (1-year time horizon).Participants Adults with COPD undergoing long-acting inhaler maintenance therapy in the UK (N=1 067,531).Interventions Inhaler maintenance therapy.Outcome measures Costs and clinical outcomes (type of treatment, rates of moderate and/or severe exacerbations, and mild-to-moderate and/or severe pneumonia events) were modelled for the two alternative pathways.Results Compared with current clinical practice, treating patients according to NICE guidance resulted in an estimated annual reduction in expenditure of £46.9 million, and an estimated annual reduction in expenditure of over £43.7 million when patients were treated according to GOLD 2020 strategy. …”
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Enhanced multifaceted model for plasmon-driven Schottky solar cells with integrated thermal effects by Brahim Aïssa, Ahmer A. Baloch, Adnan Ali, Anirban Mitra

“…This substantial rise in thermal energy highlights the critical need for advanced thermal management strategies to mitigate overheating and ensure the overall efficiency of plasmonic-enhanced solar cells. …”
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Mapping the Gaps: A Scoping Review of Virtual Care Solutions for Caregivers of Children with Chronic Illnesses by Nicole Pope, Kathyrn A. Birnie, Melanie Noel, Justine Dol, Danyu Li, Megan Macneil, Darrel Zientek, Victoria Surry, Jennifer N. Stinson

“…Significant gaps were noted in interventions for managing caregiver chronic pain, despite its high prevalence and impact on child outcomes. …”
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Role of digital technology in epidemic control: a scoping review on COVID-19 and Ebola by Amanuel Adugna, Gossa Fetene Abebe, Desalegn Girma, Melsew Setegn Alie, Tewodros Yosef, Daniel Asmelash, Dorka Dessalegn

“…As public health increasingly embraces digital innovations, collaboration among stakeholders will be crucial for effective pandemic preparedness and management.…”
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Batch biosorption studies of ammonical nitrogen (NH3-N) ions from aqueous solutions using the ubiquitous bacteria Klebsiella sp.: equilibrium, kinetic, and thermodynamic studies by Fadaa Alown, Fuad Ameen, Ashiwin Vadiveloo

“…Conclusion This study emphasizes the great ability of Klebsiella sp. to reduce NH3-N, providing important knowledge for water quality management and aquatic ecosystem preservation. Graphical Abstract…”
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Knowledge, Practices, and Attitudes Towards Silver Diamine Fluoride Therapy Among Dentists and Students in Southeastern Spain by Clara Serna-Muñoz, Marina Lucas-Porras, Yolanda Martínez-Beneyto, Amparo Pérez-Silva, Francisco Javier Ibañez-López, Antonio José Ortiz-Ruiz

“…<b>Background/Objectives:</b> The use of silver diamine fluoride (SDF) has increased in recent years for the management of caries lesions in children and adults. …”
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Quantification of Rear-End Crash Risk and Analysis of Its Influencing Factors Based on a New Surrogate Safety Measure by Qiangqiang Shangguan, Ting Fu, Junhua Wang, Rui Jiang, Shou’en Fang

“…In addition, the results of this study can be used to provide a theoretical basis for the formulation of traffic management strategies to improve driving safety.…”
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Sources analysis and risk assessment of heavy metals in soil in a polymetallic mining area in southeastern Hubei based on Monte Carlo simulation by Jing Wang, Bo Wang, Qibin Zhao, Jinnan Cao, Xiao Xiao, Di Zhao, Zhenya Chen, Di Wu

“…Based on the research results, management measures and ecological restoration suggestions are proposed, which are important for reducing soil insecurity and coping with climate change.…”
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Identification of individual-level clinical factors associated with increased risk of death during heatwaves: a time-stratified case-crossover study using national primary care rec... by Shakoor Hajat, Ross Thompson, Sari Kovats, Emer O’Connell, Helen Macintyre

“…Results presented have important implications for patient medication management during heat events, incorporating heat-risk considerations into other health policies such as suicide prevention plans and highlighted potential differences between clinical vulnerability and patients at risk.…”
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