Neoadjuvant apatinib addition to sintilimab and carboplatin-taxane based chemotherapy in patients with early triple-negative breast cancer: the phase 2 NeoSAC trial by Guoshuang Shen, Zhilin Liu, Miaozhou Wang, Yi Zhao, Xinlan Liu, Yujin Hou, Wenbiao Ma, Jingqi Han, Xiaofeng Zhou, Dengfeng Ren, Fuxing Zhao, Zitao Li, Shifen Huang, Yongzhi Chen, Yingjian He, Yan Liu, Zijun Zhu, Yongxin Li, Jinming Li, Mengting Da, Hongnan Mo, Feng Du, Liang Cui, Jing Bai, Zhen Liu, Fei Ma, Jiuda Zhao

“…Our study suggests that apatinib, sintilimab combined with carboplatin and nab-paclitaxel chemotherapy showed a promising clinical activity and manageable safety profile in early TNBC and merits further study. …”
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Based on the Gaussian Fitting Method to Derive Daily Evapotranspiration from Remotely Sensed Instantaneous Evapotranspiration by Suhua Liu, Hongbo Su, Renhua Zhang, Jing Tian, Shaohui Chen, Weimin Wang, Lijun Yang, Hong Liang

“…Evapotranspiration (ET) is a significant component in the water cycle, and the estimation of it is imperative in water resource management. Regional ET can be derived by using remote sensing technology which combines remote sensing inputs with ground-based measurements. …”
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Enhanced SVPWM Techniques for Six-Phase Inverters: Mitigation of Current Harmonics and Common Mode Voltage by Kotb B. Tawfiq, Hatem Zeineldin, Ahmed Al-Durra, Ehab F. El-Saadany

“…Reducing current harmonics and common mode voltage (CMV) holds highest importance for six-phase electric vehicles, as it not only prolongs the lifespan of crucial components but also significantly enhances overall vehicle performance, operational efficiency and improved thermal management. This article introduces an innovative switching sequence for space vector pulsewidth modulation (SVPWM) in six-phase inverters, aimed at significantly reducing CMV and total harmonic distortion (THD) of phase currents. …”
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A Study to Determine the Mediating Effect of Novelty Seeking in the Effect of Consumers’ Personal Values on Attitudes Towards Functional Foods by Selçuk Efe Küçükkambak

“…In the light of the data obtained within the scope of the research, some inferences were made to the marketing managers and suggestions were presented to the researchers for future studies. …”
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Multicomponent Dietary Supplementation: Impact on Tear Secretion and Ocular Surface Inflammation in Dry Eye Syndrome Patients by Shih-Chien Huang, Yen-Ping Lei, Min-Chien Hsiao, Yu-Kai Hsieh, Quei-Ping Tang, Connie Chen, Min-Yen Hsu

“…These findings support the potential of targeted nutritional supplementation as a safe and effective strategy for alleviating DES symptoms, offering an alternative to conventional treatments that exclusively focus on symptom management. This study highlights the role of specific nutrients in modulating tear production and inflammation, thereby providing a foundation for dietary approaches to DES treatment. …”
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Formulation for foliar and soil application of entomopathogenic nematodes for controlling the onion thrips Thrips tabaci Lindeman (Thysanoptera: Thripidae) by Hala M. S. Metwally, Mahmoud M. E. Saleh, Mokhtar Abonaem

“…Entomopathogenic nematodes (EPNs) are recommended as environmentally acceptable alternatives to chemical management for a wide range of economic insect pests. …”
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Impact of Coronary Artery Disease and Percutaneous Coronary Intervention on Transcatheter Aortic Valve Implantation by Anthony G. Matta, Thibault Lhermusier, Francisco Campelo Parada, Frederic Bouisset, Ronan Canitrot, Vanessa Nader, Stéphanie Blanco, Meyer Elbaz, Jerome Roncalli, Didier Carrié

“…The prevalence of coronary artery disease (CAD) detected in preoperative work-up for transcatheter aortic valve implantation (TAVI) is high. Instead, the management of a concomitant CAD remains unclear. We evaluate the impact of CAD and percutaneous coronary intervention (PCI) on TAVI procedures. …”
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Impact of Exercise on Tramadol-Conditioned Place Preference by Haneen Amawi, Alaa M. Hammad, Aseel Abdullah Ibrahim, Nosyba Alsbih, Frank Scott Hall, Fawaz Alasmari, Bahaa Al-Trad

“…Background: Tramadol (TRA) is an opioid that is used to manage moderate to severe pain. Long-term use of TRA can lead to the development of opioid use disorder. …”
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Continuous Glucose Monitoring Among Patients With Type 1 Diabetes in Rwanda (CAPT1D) Phase I: Prospective Observational Feasibility Study by Jason Baker, Giacomo Cappon, Jean Claude Habineza, Corey H Basch, Steven Mey, Diana L Malkin-Washeim, Christian Schuetz, Niyonsenga Simon Pierre, Etienne Uwingabire, Alvera Mukamazimpaka, Paul Mbonyi, Sandhya Narayanan

“… Abstract BackgroundThe development of minimally invasive continuous glucose monitoring systems (CGMs) has transformed diabetes management. CGMs have shown clinical significance by improving time in the euglycemic range, decreasing rates of hypoglycemia, and improving hemoglobin A1c1c ObjectiveThis study aims to determine the impact and feasibility of real-time CGM use among people living with type 1 diabetes (T1D) in Rwanda through assessment of sensor use, time in range, rates of hypoglycemia and hyperglycemia, HbA1c MethodsThe Continuous Glucose Monitoring Among Patients with Type 1 Diabetes in Rwanda (CAPT1D) study is a single-arm, prospective observational study conducted at the Rwandan Diabetes Association clinic in Kigali, Rwanda, aiming to assess the impact and feasibility of CGM use in Rwanda. …”
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Response of the germinable soil seed bank of temperate Leymus chinensis meadows to mowing regimes by Zhitao Zhang, Zhitao Zhang, Tianqi Yu, Xiaoping Xin, Hongmei Liu, Shijie Lv, Zhijun Wei, Guodong Han, Ruirui Yan

“…Mowing is a primary practice in temperate L. chinensis meadows, which are severely degraded due to frequent mowing, overgrazing, and other factors, necessitating restoration and sustainable management. The natural recovery of these grasslands hinges on their germinable soil seed banks, which form the basis for future productivity. …”
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An Improved Solar Cooling System for Date Safety and Storage under Climate of the Maghreb by Benameur Afif, Boualem Merabet, Mustafa Inc, Younes Menni, Sameer Alsharif, Ahmed Althobaiti, Ayman A. Aly

“…As a freely available energy source for managing long-term issues in energy crisis, solar energy (SE) will have to grow more to meet world’s energy demands. …”
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Exploring surgeon behavioural factors impacting the quality of care: protocol for a scoping review by Megan Delisle, Nicole Askin, Bhavan Dhaliwal, Doris Goubran, Orest Fylyma, Ina Siwach, Maziar Fazel Darbandi

“…Introduction Modern surgery incorporates many aspects of care, including preoperative workup, surgical management and multidisciplinary collaboration to achieve favourable outcomes and high patient satisfaction. …”
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Use and impact of point-of-care ultrasonography in general practice: a prospective observational study by John Brodersen, Ole Graumann, Camilla Aakjær Andersen, Martin Bach B Jensen, Annette Sofie Davidsen

“…Across applications and GPs, POCUS entailed a change in diagnoses in 49.4% of patients; increased confidence in a diagnosis in 89.2% of patients; a change in the management plan for 50.9% of patients including an absolute reduction in intended referrals to secondary care from 49.2% to 25.6%; and a change in treatment for 26.5% of patients.Conclusions The clinical utilisation of POCUS was highly variable among the GPs included in this study in terms of the indication for performing POCUS, examined scanning modalities and frequency of use. …”
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The Influence of the Farming System and Forecrop on the Yield and Chemical and Health-Promoting Composition of Spring Wheat Grain by Elżbieta Harasim, Cezary A. Kwiatkowski, Jan Buczek

“…To sum up the obtained research results, appropriate management of organic spring wheat cultivation (forecrop sugar beet or red clover, Humac Agro fertilizer) contributes to high grain nutritional quality relative to the conventional system and also reduces the yield gap relative to conventional farming.…”
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Evaluating Older Adults’ Engagement and Usability With AI-Driven Interventions: Randomized Pilot Study by Marcia Shade, Changmin Yan, Valerie K Jones, Julie Boron

“…Artificial intelligence (AI) in these technologies could also be helpful to deliver interventions that assist older adults with symptoms or self-management. Personality traits may play a role in how older adults engage with AI technologies. …”
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Biomarkers for Predicting Left Atrial or Left Atrial Appendage Thrombus in Anticoagulated Patients with Nonvalvular Atrial Fibrillation by Xue Zhou, Zuolan Wang, Shuang Dou, Kangyin Chen, Enzhao Liu, Tong Liu, Guangping Li, Jingjin Che

“…Therefore, these might be considered as useful prognostic markers in the management and treatment of NVAF patients.…”
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Relationship between muscle activation and sagittal knee joint biomechanics in patients with patellofemoral pain syndrome: a cross-sectional study by Byung Sun Choi, Soon Bin Kwon, Sehyeon Jeon, Myeongjun Kim, Yunseo Ku, Du Hyun Ro, Hyuk-Soo Han

“…Conclusions Patients with PFPS exhibit elevated muscle activation, particularly in response to changes in the knee extension moment, which is likely a compensatory mechanism to manage knee joint loading during gait. These results highlight altered neuromuscular adaptations in PFPS, suggesting targeted therapies may help improve functional outcomes. …”
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PROTACs: Mechanism and Bioavailability enhancement strategies by nanotechnology, RNA viral infections (vaccine strategy) and Prodrug development by Sanaul Mustafa, Md Sabir Hussain Siddiquee

“…An idea for the field of antiviral therapy, this invention defines a new horizon for the management of diseases that have not responded to traditional methods. …”
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Successful Antiviral Treatment with Direct-Acting Antivirals for Hepatitis C Virus Infection during Peritransplant Period in a Kidney Transplant Recipient by Giovanni Varotti, Ferdinando Dodi, Ernesto Paoletti, Andrea Bruno, Iris Fontana

“…New direct-acting antiviral agents (DAA) have dramatically changed the therapy management for HCV, showing promising results in terms of sustained virologic response. …”
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PREDISPOSITION FACTORS ANALYSIS FOR FOURNIER'S GANGRENE DEFECTS CLOSURE COMPLICATION by Bayu Fasi Bermani, Sitti Rizaliyana, Ira Handriani

“…The study aims to share our policy in managing Fournier's gangrene and identifying risk factors that can affect the outcome of defect closure. …”
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