E3 Ubiquitin Ligase CHIP Inhibits the Interaction between Hsp90β and MAST1 to Repress Radiation Resistance in Non-Small-Cell Lung Cancer Stem Cells by Bo Tan, Jingwei Zhang, Wen Wang, Haibo Ma, Yuanyuan Yang

“…The radiation resistance of cancer stem cells poses a critical obstacle for management of non-small-cell lung cancer (NSCLC). It is interesting to note that E3 ubiquitin ligase CHIP is involved in radiation resistance and stemness phenotypes in NSCLC, while the downstream mechanisms remain elusive. …”
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Increased sensitivity in electron–nuclear double resonance spectroscopy with chirped radiofrequency pulses by J. Stropp, N. Wili, N. C. Nielsen, D. Klose

“…In 2D triple resonance experiments (TRIPLE), the signal increase exceeds 10 times for some lines, thus making chirped 2D TRIPLE experiments feasible even for broad peaks in manageable acquisition times.</p>…”
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Immuno-Inflammatory Characteristics in Low Severity COVID-19 Patients with Digestive Symptoms by Caihan Duan, Shengyan Zhang, Jian Wang, Wei Qian, Chaoqun Han, Xiaohua Hou

“…Prevention and clinical management of this type should be taken into consideration.…”
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Overnight oximetry in children undergoing adenotonsillectomy: a single center experience by C. Carrie Liu, Kathleen H. Chaput, Valerie Kirk, Warren Yunker

“…This study investigates whether factors influence surgeons in selecting patients for home-based sleep oximetry, how the study findings are used in patient management, and whether abnormal oximetry findings are associated with post-operative complications. …”
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Improving diagnostic precision in thyroid nodule segmentation from ultrasound images with a self-attention mechanism-based Swin U-Net model by Changan Yang, Muhammad Awais Ashraf, Mudassar Riaz, Pascal Umwanzavugaye, Kavimbi Chipusu, Kavimbi Chipusu, Hongyuan Huang, Yueqin Xu

“…This method represents a significant step toward more reliable and precise diagnostics in thyroid disease management, with potential implications for enhanced patient outcomes in clinical practice.…”
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Polypore fungi as a flagship group to indicate changes in biodiversity – a test case from Estonia by Kadri Runnel, Otto Miettinen, Asko Lõhmus

“…Four broad ecological patterns are described: (1) polypore assemblage organization in natural forests follows major soil and tree-composition gradients; (2) landscape-scale polypore diversity homogenizes due to draining of peatland forests and reduction of nemoral broad-leaved trees (wooded meadows and parks buffer the latter); (3) species having parasitic or brown-rot life-strategies are more substrate-specific; and (4) assemblage differences among woody substrates reveal habitat management priorities. Our update reveals extensive overlap of polypore biota throughout North Europe. …”
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Scoping review of brucellosis in Cameroon: Where do we stand, and where are we going? by Christopher G Laine, Abel Wade, H Morgan Scott, Rosina C Krecek, Angela M Arenas-Gamboa

“…Cameroon has an opportunity to build public and animal health infrastructure, leading the way for central Africa in the management and future eradication of brucellosis.…”
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Comprehensive Monitoring Research on the Effect of Roof Cutting and Pressure Release: A Case Study of the Jiulishan Coal Mine in China by Lei Huang, Shengli Yang, Yanchun Xu, Yaqi Luo, Hongzhi Yuan

“…The longwall panel of the Jiulishan coal mine is affected by floor-confined water, while the roof rock weighting makes the production management of some longwall panels difficult. This has caused engineering methods of roof cutting and pressure release to be considered. …”
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ASSESSING THE RESULTS OF TRAINING IN DIGITAL ENTREPRENEURSHIP IN THE AGE OF HIGH AND DEEP TECH by Oleg Kaminsky, Julia Yereshko, Sergii Kyrychenko, Maryna Duchenko

“…In addition, we are seeing a shift in the basic skills needed in science, research and development, engineering, IT, management, entrepreneurship, and more. These skills are transformed in accordance with the technological restructuring of productive forces, at the same time, educational activity is characterized by some lag in its development. …”
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Biomimetic bioreactor for potentiated uricase replacement therapy in hyperuricemia and gout by Bin Yang, Bin Yang, Guihu Luo, Tailei Nie, Zhenglan Ban, Quanxin Ning, Jialin Zhang, Xiangru Liu, Yanhua Lin, Xiaochun Xie, Qianyun Chen, Han Zhong, Ying Huang, Pan Liao, Yan Liu, Chenyang Guo, Chuanxu Cheng, Erwei Sun, Erwei Sun

“…IntroductionUricase replacement therapy is a promising approach for managing hyperuricemia and gout but is hindered by challenges such as short blood circulation time, reduced catalytic activity, and excessive hydrogen peroxide (H2O2) production. …”
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U-shaped association between TC/HDL-C ratio and osteoporosis risk in older adults by Chuanwei Zhao, Xiaochun Zhang, Xu Zhang, Bo Zhao, Yane Yang, Mu Lin, Wenli Qiao, Zeyao Hu, Haijie Yang

“…Further longitudinal studies are required to validate these findings and determine optimal lipid management strategies for osteoporosis prevention.…”
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Inside the impulsive brain: a narrative review on the role of neurobiological, hormonal and genetic factors influencing impulsivity in psychiatric disorders by Hannah Raji, Susha Dinesh, Sameer Sharma

“…Substantial contributions from neurotransmitters like dopamine and serotonin to impulsive behavior underscore the imperative need for genetic and neurochemical investigations to identify factors crucial for effective management. Interconnections between stress, impulsivity, and decision-making are accentuated, particularly in mood disorders. …”
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Clerodendrum volubile Ethanol Leaf Extract: A Potential Antidote to Doxorubicin-Induced Cardiotoxicity in Rats by Olufunke Esan Olorundare, Adejuwon Adewale Adeneye, Akinyele Olubiyi Akinsola, Daniel Ayodele Sanni, Mamoru Koketsu, Hasan Mukhtar

“…Overall, CVE may play a significant therapeutic role in the management of DOX-induced cardiotoxicity in humans.…”
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Impact of underweight status on mortality in sepsis patients: a meta-analysis by Jiaan Chen, Fan Zhang, Li Liang, Xuming Pan, Jiancheng Zhang, Guangjun Jin

“…Physicians should pay more attention to the management of underweight sepsis patients.Systematic review registrationhttps://www.crd.york.ac.uk/PROSPERO/display_record.php?…”
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Awareness, attitude, and acceptance of newborn screening for sickle cell disease among health workers and caregivers at primary healthcare centers in Gwagwalada Area Council, Feder... by Isa Hezekiah A, Chisomaga Ifeanyi Oparaugo, Grace Doyin Ajetomobi, Ayomide Esther Fasina, Reuben Ikechukwu Chianumba, Obiageli Eunice Nnodu, Obiageli Eunice Nnodu

“…The majority, 175 (59.1%) of the caregivers strongly agreed that NBS for SCD helps in the early detection and management of SCD, while 7 (2.4%) disagreed. Notably 272 (90.4%) of the caregivers had secondary and tertiary education. …”
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Magnetohydrodynamic nanofluids flow and heat transfer with radiative heat flux and exothermic chemical reactions by Md. Mehedi Hasan, M.J. Uddin, Salah A. Faroughi

“…Nanofluids are highly effective in optimizing thermal management in engineering systems. The complex and multifaceted properties of nanofluids require in-depth exploration that transcends their immediate technological and environmental applications. …”
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Tracking pygmy blue whale diving behaviour and validation of foraging areas defined from horizontal movement data by Michele Thums, Luciana C. Ferreira, Andrew Davenport, Micheline Jenner, Luciana Möller, Grace Russell, Robert D. McCauley, Curt Jenner

“…Our test of movement models to define foraging is extremely useful given its common usage in ecology and our spatial delineation of foraging areas assists with conservation management.…”
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Chitosan oligosaccharides maintained postharvest quality and increased shelf life of mango by Nishat Nitu, Md. Sefat Ullah, Prianka Howlader, Md. Nazmul Mehedi, Habiba Meem, Santosh Bose

“…It exhibits very short shelf life mainly due to high respiration rate, susceptible to various storage pathogens and mechanical injuries at the time of postharvest management which lead to reduce the quality. However, the experiment was carried out to investigate the chitosan oligosaccharides (COS) coating effects on postharvest quality and shelf life of mango varieties. …”
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Endovascular Treatment of Mirror Aneurysms in Subarachnoid Hemorrhage Patients: Single Stage or Multiple Stage? by Yunfei Song, Guoqiang Song, Guijing Liu, Limei Mao, Xiuhu An, Chao Peng, Jian Li, Yan Chen, Hongwen Li, Changkai Hou, Bangyue Wang, Yan Zhao, Xiangdong Wang, Gangfeng Yin, Xinyu Yang

“…In the single‐stage cohort, all 114 aneurysms in 57 patients were managed during a single session. During the 2‐year follow‐up, it was observed that 49 patients achieved a modified Rankin Scale score ≤2. …”
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Quantitative Changes in Vascular and Neural Fibers Induced by Subretinal Fluid Excluding the Peripapillary Region in Patients with Chronic Central Serous Chorioretinopathy by Esra Kızıldağ Özbay, Şenol Sabancı, Mehmet Fatih Küçük, Muhammet Kazım Erol

“…These findings suggest that SRF contributes to broader retinal alterations and supports the need for early detection and management of CSCR to prevent long-term visual impairment.…”
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