Unraveling ankylosing spondylitis: Exploring the genetic and immunological factors and latest treatment innovations by Nilasree Hazra, Sudeshna Sengupta, Dipannita Burman, Jyoti Sekhar Banerjee, Malavika Bhattacharya

“…Some case studies suggest that an Ayurvedic approach, including Panchakarma treatments and specific Ayurvedic medications, may be beneficial in managing AS. HLA-B27 and non-HLA genes such as IL23R, ERAP1, and RUNX3 are linked to AS susceptibility. …”
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Senescent cell depletion alleviates obesity-related metabolic and cardiac disorders by Tábatha de Oliveira Silva, Guilherme Lunardon, Caroline A. Lino, Amanda de Almeida Silva, Shiju Zhang, Maria Cláudia Costa Irigoyen, Yao Wei Lu, John D. Mably, Maria Luiza M. Barreto-Chaves, Da-Zhi Wang, Gabriela P. Diniz

“…Although senescent cells have been shown to accumulate in adipose tissue, the role of senescence in obesity-induced metabolic disorders and in cardiac dysfunction is not yet clear; therefore, the therapeutic potential of managing senescence in obesity-related metabolic and cardiac disorders remains to be fully defined. …”
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An Efficient and Hybrid Deep Learning-Driven Model to Enhance Security and Performance of Healthcare Internet of Things by Muhammad Babar, Muhammad Usman Tariq, Basit Qureshi, Zabeeh Ullah, Fahim Arif, Zahid Khan

“…In this method, we have first considered SDN architecture as a promising solution since it allows for reconfiguration over static network infrastructure and manages the distributed architecture of intelligent H-CIoT networks by keeping the data and control planes apart. …”
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Effect of Green Roofs on the Thermal Environment of Prototype Broiler Houses by Maria Angela de Souza, Fernanda Campos de Sousa, Alex Lopes da Silva, Thauane Cordeiro Soares, Charles Paranhos Oliveira, Ricardo Brauer Vigoderis, Fernando da Costa Baêta, Ilda de Fátima Ferreira Tinôco

“…The management of thermal environments in animal production facilities presents significant challenges, requiring continuous adjustments to meet animals’ physiological needs. …”
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Understanding the Rural–Rural Migration of Health Workers in Two Selected Districts of Tanzania by Nathanael Sirili, Daudi Simba

“…For the qualitative sub-study, 14 key informants that included health facilities in-charges and district health managers from the two districts were interviewed. In addition, three focus group discussions were conducted with members of the health facilities committee, in the two districts. …”
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An umbrella review of physical-activity therapy and cognitive behavioral therapy in reducing fear of falling among community-dwelling older adults: insights on intervention intensi... by Yuan Sheng, Caili Wang, Yan Wang, LunPing Pan, Mengmeng Zhang, Deshan Liu, Wei Gao

“…The umbrella review found that PAT and CBT interventions can effectively manage FOF. Comparable improvements were reported with low- and moderate-intensity PAT intervention (p < 0.0001); Significant improvements were observed with CBT immediately post-intervention, in the short-term (<6 months), and in the long-term (≥6 months) (p < 0.0001).DiscussionOur study revealed that a comprehensive intervention strategy combining low or moderate PAT with CBT interventions is more effective than isolated approaches, as it addresses the multifaceted nature of fear and fall risk. …”
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Tumor Markers in Pleural Fluid: A Comprehensive Study on Diagnostic Accuracy by Vladimir Aleksiev, Daniel Markov, Kristian Bechev

“…These findings pave the way for improved diagnostic accuracy and personalized clinical management, addressing a critical gap in the care of patients with pleural pathologies.…”
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Underutilized wild edible fungi and their undervalued ecosystem services in Africa by Gudeta W. Sileshi, Donatha D. Tibuhwa, Alec Mlambo

“…Therefore, we recommend national forestry research and development programs and international frameworks such as Reducing Emissions from Deforestation and Degradation (REDD +) to invest in the conservation, cultivation and valorisation of wild edible mushrooms to achieve sustainable forest management and the welfare of local communities.…”
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Impacts of continuing education on Primary Health Care professionals-A scoping review protocol. by Laianny Krizia Maia Pereira, José Adailton da Silva, Ricardo A de M Valentim, Thaísa G F M S Lima, Nésio Fernandes de M Junior, Alexandre R Caitano, Tatyana Souza Rosendo

“…Studies published between 2007 and 2024 will be included, and no language restrictions will be applied. The Rayyan management software will be used as a tool to support the selection of studies. …”
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Impact of tiered restrictions in December 2020 on COVID-19 hospitalisations in England: a synthetic control study by Daniel Hungerford, Benjamin Barr, Mark Green, Marta García-Fiñana, Iain Buchan, Xingna Zhang

“…Our findings suggest that regionally targeted restrictions can be effective in managing infectious diseases.…”
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Spatiotemporal dynamics of carbon sequestration capacity and its determinants in rubber plantation ecosystems of Hainan Island by Yinghe An, Zhixiang Wu, Runqing Zhang, Xiang Zhang, Zhenghong Tan, Zhongyi Sun

“…These findings provide a basis for managing and improving carbon sequestration in plantations.…”
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Beyond the fever: shotgun metagenomic sequencing of stool unveils pathogenic players in HIV-infected children with non-malarial febrile illness by Patricia Nabisubi, Stephen Kanyerezi, Grace Kebirungi, Ivan Sserwadda, Mike Nsubuga, Grace Kisitu, Patricia Ntege Nahirya, Bonny Mulindwa, George P. Akabwai, Sylvia Nantongo, Adeodata Kekitiinwa, Edgar Kigozi, Nsubuga Moses Luutu, Fred Ashaba Katabazi, Leymon Kalema, Andrew Katabalwa, Daudi Jjingo, Gerald Mboowa

“…While traditional diagnostic approaches focus on specific pathogens, shotgun metagenomic sequencing offers a comprehensive tool to explore the microbial landscape underlying NMFI in this vulnerable population ensuring effective management. Methods In this study, we employed shotgun metagenomics to analyse stool samples from HIV-infected children at the Baylor Children’s Clinic Uganda presenting with non-malarial febrile illness. …”
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Clinical Characteristics and Outcomes of COVID-19 in Children in Northern Iran by Leila Shahbaznejad, Hamed Rouhanizadeh, Mohammad Reza Navaeifar, Fatemeh Hosseinzadeh, Faeze Sadat Movahedi, Mohammad Sadegh Rezai

“…Patients’ age, gender, clinical symptoms, and signs, in addition to therapeutic management and outcomes, were reported. Results. 57 (57%) boys and 43 girls with the mean age of 104.63±79.14 months were evaluated. 20 patients (20%) were transferred to the PICU (pediatric intensive care unit), and 13 children experienced a severe form of the disease, pediatric inflammatory multisystem syndrome (PIMS). …”
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Therapeutic strategies for fungating and ulcerating breast cancers: A systematic review and narrative synthesis by Valentina Zagardo, Mandara Harikar, Gianluca Ferini

“…Background: To identify optimal therapeutic strategies for managing fungating, large or ulcerating breast tumors and highlight existing gaps in the literature. …”
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Diversity of Stemphylium spp. of onion and garlic revealed the differential pathogenicity and in vitro efficacy of different growth suppressors by Md. Morshedul Islam, Sabmira Showkat Silvi, Shila Chakraborty, Md. Atiqur Rahman Khokon

“…Additionally, SA, BA, and CHI showed growth suppressive effects and can be utilized as alternative compounds to toxic fungicides in the existing integrated disease management package in Bangladesh.…”
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Evaluation of urban water cycle health status based on DPSIRM framework and AHP-FCE-Cloud model by Jiageng Hu, Fuqiang Wang, Peiheng Liu, Subing Lü, Cheng Lü, Furong Yu

“…This study employs the Driving force-Pressure-State-Impact-Response-Management (DPSIRM) framework, using key policy implementation milestones as benchmarks to divide the timeline into three evaluation phases, thereby optimizing the urban water cycle health evaluation system. …”
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Wide-ranging and Violent Volcanic History of a Quiet Transborder Area: Volcanic Geoheritage of the Novohrad–Nógrád UNESCO Global Geopark by Szabolcs Harangi, Imre Szarvas, Réka Lukács

“…This is an evolving geopark, where continuously renewing attractions serve the geoeducation and geotourism purposes in parallel with geoheritage conservation management.…”
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L'approche écosystémique de la santé des populations : le cas de l’exposition au mercure des communautés riveraines de l’Amazonie et du nord du Québec by Sebastian Weissenberger, Delaine Sampaio da Silva, Roger Schetagne

“…In the absence of any options to reduce the mercury contamination in the affected ecosystems, the emphasis has been put on monitoring and on the management and communication of health risks. The main strategy in order to reduce the population’s exposure to methylmercury has been to influence people’s diet, without discouraging the overall consumption of fish, which has numerous health, economic and social benefits. …”
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Comparison of the Efficacies of Sacrospinous Ligament Fixation and Laparoscopic Lateral Suspension in the Treatment of Apical Prolapse: 24-Month Follow-Up Results by Engin Yurtcu, Betul Keyif, Burcu Sarigedik, Alper Basbug, Andrea Tinelli

“…Although conservative treatments provide some symptom relief, surgical interventions are more effective for managing POP. This study compares the outcomes and effectiveness of sacrospinous ligament fixation (SSLF) and laparoscopic lateral suspension (LLS) surgeries in the treatment of POP. …”
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Efficacy and safety of trabeculectomy versus peripheral iridectomy plus goniotomy in advanced primary angle-closure glaucoma: study protocol for a multicentre, non-inferiority, ran... by Keith Barton, Tin Aung, Ling Jin, Ping Lu, Xiulan Zhang, Robert N Weinreb, Yi Zhang, Li Tang, Guangxian Tang, Hengli Zhang, Aiguo Lv, Huiping Yuan, Yunhe Song, Fengbin Lin, DENNIS S C LAM, Lin Xie, Kun Hu, Xiaohong Liang, Yingzhe Zhang, Wulian Song, Xiaomin Zhu, Xinbo Gao, Sujie Fan, Yuying Peng, Mengfei Liao, Xin Nie, Ki-Ho Park

“…Minimally invasive glaucoma surgery (MIGS) plays an increasing role in the management of glaucoma due to its safer and faster recovery profile; cataract surgery-based MIGS is the most commonly performed such procedure in PACG. …”
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