The role of the C5a-C5aR pathway in iron metabolism and gastric cancer progression by Qinxue Ni, Hong Yang, Hang Rao, Liyong Zhang, Mengyuan Xiong, Xiao Han, Boshao Deng, Lulu Wang, Jian Chen, Yan Shi

“…Our data suggest a pivotal role of the C5a-C5aR pathway in tumor iron management, indicating that targeting its regulatory mechanisms may pave the way for future iron-targeted therapeutic approaches in cancer treatment.…”
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Research on the quantitative relationship between stress shadow effect of multiple thick and hard key layers and surface subsidence by Jianqiao Luo, Yupeng Shen, Xin Meng, Tuo Yang

“…Abstract For a long time, the management of surface structures such as villages and rivers affected by underground coal mining has been a popular and difficult issue in coal mining. …”
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External Body Scores in Male Sakub Sheep Based on Different Physiological Age by Denis Agita Meliana, Agustinah Setyaningrum, Akhmad Sodiq, Agus Susanto

“…This information is critical for optimizing management strategies in Sakub sheep production, particularly in breeding and selection programs aimed at enhancing productivity and carcass quality. …”
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Case report: Tongue metastasis as an initial sign of clear cell renal cell carcinoma and its prognosis by Shuo Liu, Hongyun Liu, Bowen Weng, Sichuan Hou

“…This case highlights the urgent need for improved therapeutic strategies to manage symptoms and prolong survival in patients with this rare metastatic presentation.…”
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<i>In Silico</i> PASS Predictions and Exploration of Antioxidant and Anti-inflammatory Activity of <i>Citrus Karna</i> Raf. Fruit by Prasad JAMKHANDE, Mahavir GHANTE, Rajeshwar KSHIRSAGA

“…Most anti-inflammatory agents used in the management of inflammatory disorders diminish oxidative damage. …”
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The Role of Beta-hCG Progesterone and Creatine Kinase in the Early Diagnosis of Ectopic Pregnancies by Nagihan Sarı, Hatice Işık, Hatice Başar, Ali Seven, Ahmet Bostancı

“…Serum samples were taken from patients for β-hCG, progesterone and creatine kinase before any management. SPSS for Windows 11,5was used for the analysis of the data. …”
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Proximity-based solutions for optimizing autism spectrum disorder treatment: integrating clinical and process data for personalized care by Annarita Vignapiano, Annarita Vignapiano, Francesco Monaco, Francesco Monaco, Stefania Landi, Luca Steardo, Carlo Mancuso, Claudio Pagano, Gianvito Petrillo, Alessandra Marenna, Martina Piacente, Stefano Leo, Carminia Marina Ingenito, Rossella Bonifacio, Benedetta Di Gruttola, Marco Solmi, Marco Solmi, Marco Solmi, Marco Solmi, Maria Pontillo, Giorgio Di Lorenzo, Giorgio Di Lorenzo, Alessio Fasano, Alessio Fasano, Alessio Fasano, Giulio Corrivetti, Giulio Corrivetti

“…Rigorous data governance measures will ensure ethical and secure data management. This project will improve access to care, personalize treatments for better outcomes, shorten wait times, boost patient involvement, and raise ASD awareness, leading to better resource allocation. …”
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Epidemiology of snake bites and envenomations in the Bofidji Group – West, Equateur Province, Democratic Republic of the Congo by Blaise Engomba Mokekola, Jean-Paul Koto-Te-Nyiwa Ngbolua, Guy Bayeli Ilumbe, Idrissa Zabo Assumani, Aristarque Mulonda, Monizi Mawunu, Gires Mboyo Engomba, Colette Ashande Masengo, Godefroid Libono Ekamba

“…Conclusion This study underscores the need for improved healthcare infrastructure and preventive strategies to effectively manage snakebites. While traditional treatments have value, their limitations highlight the importance of integrating modern healthcare practices and educating rural populations on prevention measures. …”
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Spatial-temporal evolution of habitat quality in tropical monsoon climate region based on “pattern–process–quality” – a case study of Cambodia by Kang Junmei, Yang Fengshuo, Wang Jun, Liu Yang, Fang Dengmao, Jiang Chengcheng

“…Exploring the coupling relationship of “pattern–process–quality” is conducive to understanding the internal mechanism of habitat quality change, and is of great significance for the function maintenance and sustainable management of regional ecosystems. Existing studies mainly analyze the spatial-temporal evolution of habitat quality from the perspective of “pattern quality” and land use data. …”
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Study on Influencing Factors and Countermeasures of Elderly Nursing Services in the Elderly by Shuo Liu, Li Chen, Dandan Li, Qianqian Yang, Fangfang Liu, Yanli Cheng

“…Therefore, relevant units should strengthen the health examination of the elderly, provide high-quality medical services, make full use of health resources, and strengthen nursing management, so as to improve the quality of nursing services. …”
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The legal relevance of unilateral copyright statements on websites by D. I. Shmatkov, D. V. Pashniev, O. V. Khliestkov, S. O. Kolomiitsev

“…The choice of websites of scientific institutions is justified by two factors: the specifics of the activity, which involves the generation of large volumes of original works and the paradigm of open science which imposes new requirements on copyright management. It has been established that the use of a unilateral copyright statements is quite complex and debatable. …”
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Factors associated with fear of hypoglycaemia among the T1D Exchange Glu population in a cross-sectional online survey by Jingwen Liu, Jeoffrey Bispham, Ludi Fan, Jiat-Ling Poon, Allyson Hughes, Alicia Mcauliffe-Fogarty, Oralee Varnado, Beth Mitchell

“…Objectives Fear of hypoglycaemia (FoH) has been associated with suboptimal diabetes management and health outcomes. This study investigated factors associated with behavioural and emotional aspects of FoH among adults living with type 1 diabetes (T1D) mellitus.Design Cross-sectional study.Setting Online survey hosted on T1D Exchange Glu, an online community for patients living with T1D mellitus.Measures The Hypoglycaemia Fear Survey II-short form and the Hypoglycaemic Attitudes and Behaviour Scale were used to assess FoH. …”
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Urethral Prolapse Case Report: Surgical and Social Considerations in Senegal by Mohamed Jalloh, Jennifer Heibig, Oumar Gaye, William Ghaul, Gabrielle Yankelevich, Medina Ndoye, Mouhamadou Moustapha Mbodji, Ayun Cassell, Lamine Niang, Serigne Magueye Gueye

“…Urethral prolapse is a rare condition which can be managed successfully by surgery. Plain Language Summary. …”
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Planning analysis, planning approaches and design of the new city of Tis In line with the regional development of Makran Coast by Badil Sancholi, Maryam Karimian Bostani, Masoumeh Hafez Rezazadeh

“…The establishment of new cities and settlements and the development of economic and industrial activities on the shores of Makran, is inevitable, and since the creation and development of new cities has been one of the policies in land management in recent decades, planning and designing a new city in Regional development orientation of this region is essential. …”
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Alpelisib-Induced Diabetic Ketoacidosis and Insulin-Resistant Hyperglycemia by Michael Loke, DO, Vishal Sehgal, MD, Niraj Gupta, MD

“…The objective of this report is to describe a patient with alpelisib-induced diabetic ketoacidosis and the difficulties of management. Case Report: A 59-year-old woman was admitted to the hospital with a history of noninsulin dependent type 2 diabetes on metformin presented with diabetic ketoacidosis. …”
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Spatial Downscaling of Daily Temperature Minima Using Machine Learning Methods and Application to Frost Forecasting in Two Alpine Valleys by Sudheer Bhakare, Michael Matiu, Alice Crespi, Dino Zardi

“…Despite the decreased skills for extended forecast periods, results suggest that the CNN model’s effectiveness for spatial downscaling of minimum temperature and frost forecasting over complex terrain provides a valuable tool for frost risk management.…”
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Application of IgG-Derived Natural Treg Epitopes (IgG Tregitopes) to Antigen-Specific Tolerance Induction in a Murine Model of Type 1 Diabetes by Leslie P. Cousens, Yan Su, Elizabeth McClaine, Xin Li, Frances Terry, Robert Smith, Jinhee Lee, William Martin, David W. Scott, Anne S. De Groot

“…Implementation of these defined regulatory T cell epitopes for therapy of T1D and other autoimmune diseases may lead to a paradigm shift in disease management.…”
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Enhancing Pan evaporation predictions: Accuracy and uncertainty in hybrid machine learning models by Khabat Khosravi, Aitazaz A. Farooque, Amir Naghibi, Salim Heddam, Ahmad Sharafati, Javad Hatamiafkoueieh, Soroush Abolfathi

“…Pan Evaporation (Ep) plays a pivotal role in water resource management, particularly in arid and semi-arid regions. …”
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Epidemiological, Clinical and Paraclinical Profile of Paediatric Malaria at University Hospital Centre Amissa Bongo in Franceville, Gabon by Roméo Karl Imboumy-Limoukou, Jean Claude Biteghe-Bi-Essone, Sandrine Lydie Oyegue-Liabagui, Jean Jordan Ekogha-Ovono, D’Alva Noronha Ingrid Nascimento, Steede Seinnat Ontoua, Cherone Nancy Mbani Mpega Ntigui, Lady Charlène Kouna, Jean Bernard Lekana-Douki

“…Conclusion: Non-compliance with preventive measures and the misuse of antimalarials further complicate the clinical picture, requiring parenteral management for the most part.…”
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Risk Factors Analysis of Cutaneous Adverse Drug Reactions Caused by Targeted Therapy and Immunotherapy Drugs for Oncology and Establishment of a Prediction Model by Zimin Zhang, Mingyang Zhu, Weiwei Jiang

“…These findings have important implications for optimizing therapeutic efficacy and maintaining the quality of life of patients from the perspective of managing cutaneous adverse drug reactions. Trial Registration: ChiCTR2400088422…”
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