Heart failure with mildly reduced ejection fraction: retrospective study of ejection fraction trajectory risk by Robert J.H. Miller, Majid Nabipoor, Erik Youngson, Gynter Kotrri, Nowell M. Fine, Jonathan G. Howlett, Ian D. Paterson, Justin Ezekowitz, Finlay A. McAlister

“…Categorizing HFmrEF patients based on LVEF trajectory provides meaningful clinical information and may assist clinicians with management decisions.…”
Get full text

Multi-generational adaptation to Solanum nigrum increases reproduction and decreases microbial diversity of Aphis gossypii by Peng Wang, Peng Wang, Yu-Xi Jing, Ya-Jie Ma, Ya-Jie Ma, Dan Wang, Yong-Pan Shan, Hongyan Hu, Changcai Wu, Xian-Peng Song, Xiangliang Ren, Xiangliang Ren, Xiangliang Ren, Yan Ma, Yan Ma, Yan Ma, Xiaoyan Ma, Xiaoyan Ma, Xiaoyan Ma

“…These findings provide a theoretical foundation for the scientific management of A. gossypii and S. nigrum in the fields.…”
Get full text

Cryptic species and hybridisation in corals: challenges and opportunities for conservation and restoration by Riginos, Cynthia, Popovic, Iva, Meziere, Zoe, Garcia, Vhon, Byrne, Ilha, Howitt, Samantha M., Ishida, Hisatake, Bairos-Novak, Kevin, Humanes, Adriana, Scharfenstein, Hugo, Richards, Thomas, Briggs, Ethan, Clark, Vanessa, Lei, Chuan, Khan, Mariam, Prata, Katharine E.

“…The conservation and management of coral reef ecosystems will benefit from accurate assessments of reef-building coral species diversity. …”
Get full text

تفکیک سهم تغییر اقلیم و فعالیت‌های انسانی بر تغییرات دبی رودخانه با استفاده از رویکرد تحلیل حساسیت هیدرولوژیکی مبتنی بر فرضیه بودیکو مطالعه موردی: شوره‌زار دشت قزوین... by سارا حشمتی, بیژن نظری, محمد رضا نیکو

Get full text

Global research trends in Chinese medicine for the treatment of non-alcoholic fatty liver disease (NAFLD): A bibliometric study by Kangjie li, Jie Wang, Ming Dang, Runxin Ren, Maomao Fu, Jing Wang, Qiao Zhang, Chongbo Zhao

“…Recent studies have also highlighted TCM's ability to regulate gut microbiota, offering a promising avenue for NAFLD management. To better understand the evolving role of TCM in treating NAFLD, a comprehensive analysis of existing research is necessary. …”
Get full text

Risk factors for methotrexate treatment failure in tubal ectopic pregnancy: a retrospective cohort study by Linru Fu, Xinyan Liu, Zhao Tian, Zhe Du, Xinyi Wang, Xiuqi Wang, Xiaodong Li, Tao Xu, Zhijing Sun

“…Methotrexate (MTX) is a noninvasive and effective medical management option for TEP, but failure rates range from 10 to 36%, posing challenges in clinical practice. …”
Get full text

The Role of Open and Distance Learning (ODL) in Promoting Access to Women's Education in Northwestern Nigeria: A Case Study of the National Open University of Nigeria (NOUN) by Shehu Usman Adamu, Bala Kwata Waziri, Adewale Adesina, Babangida Iro

“…Faculties of Agric, Arts, Education Law and Management had enrolment figures of 134 (0.52%), 634 (2.53%), 3,921 (15.4%8), 98 (0.38%), 2,954 (11.66%) respectively while Faculty of Social Sciences had 3,311 (13.07%). …”
Get full text

Assessing Facial Thermal Nociceptive Response in Female Dogs After Elective Ovariohysterectomy Anesthetized with Isoflurane and Treated with Cannabidiol and Meloxicam Analgesia by Alejandro Casas-Alvarado, Patricia Mora-Medina, Ismael Hernández-Avalos, Julio Martínez-Burnes, Agatha Miranda-Cortes, Adriana Domínguez-Oliva, Daniel Mota-Rojas

“…Pain management requires the identification of certain indicators to recognize pain. …”
Get full text

Diagnóstico y tratamiento de los trastornos de la presión intracraneal: Documento de consenso del Grupo de Estudio de Cefaleas de la Sociedad Española de Neurología by J. García-Ull, N. González-García, M. Torres-Ferrús, D. García-Azorín, I.F.J. Molina-Martínez, I. Beltrán-Blasco, S. Santos-Lasaosa, G. Latorre, A.B. Gago-Veiga, J.M. Láinez, J. Porta-Etessam, C. Nieves-Castellanos, A. Mínguez-Olaondo, A. López-Bravo, S. Quintas, N. Morollón, S. Díaz-Insa, R. Belvís, P. Irimia

“…Therefore, the Spanish Society of Neurology's Headache Study Group considered it necessary to prepare this consensus document with the inclusion of diagnostic and therapeutic algorithms to facilitate and improve their management in clinical practice.This document was created by a committee of experts of the Spanish Society of Neurology's Headache Study Group based on a systematic review of the literature, incorporating the experience of the participants, and establishing practical recommendations with levels of evidence and grades of recommendation.…”
Get full text

EDF1 accelerates ganglioside GD3 accumulation to boost CD52-mediated CD8+ T cell dysfunction in neuroblastoma by Di Li, Meng Li, Zhenjian Zhuo, Huiqin Guo, Weixin Zhang, Yile Xu, Hai-Yun Wang, Jiabin Liu, Huimin Xia, Huiran Lin, Jue Tang, Jing He, Lei Miao

Get full text

Associations of arthritis with functional disability and depressive symptoms in general US adults: NHANES 1988–1994 and 1999–2018 by Xiaoting Liu, Yunzhen Huang, Jinjing Fu, Mayila Mohedaner, Danzengzhuoga, Gan Yang, Zhenqing Yang, Xueqin Li, Xinye Ma, Qiqi Zhang, Zuyun Liu, Xifeng Wu, Zhimin Ying

“…Above findings seek to highlight the need for comprehensive physical and mental health management in individuals with arthritis. Methods We designed a cross‐sectional study utilizing multivariable logistic regression models to examine the associations. …”
Get full text

Weight-based enoxaparin thromboprophylaxis in young trauma patients: analysis of the CLOTT-1 registry by Sarah Lombardo, Ram Nirula, Elliott R Haut, Scott Brakenridge, Brandon Bruns, Charles E Wade, M Margaret Knudson, Thomas Scalea, Todd W Costantini, Lisa Marie Knowlton, David Spain, Ernest E Moore, Michelle K McNutt, Matthew J Martin, Andrew J Kerwin, George C Velmahos, Bruce Crookes, Marta McCrum, Lucy Kornblith, Mark D Cipolle, Laszlo N Kiraly, David J Milia, Alicia Mohr, Frederick Rogers, Sherry Sixta, Jade Nunez

“…Further studies need to evaluate these findings across a wider age and comorbidity spectrum.Level of evidence Level IV, therapeutic/care management.…”
Get full text

The fibronectin-targeting PEG-FUD imaging probe shows enhanced uptake during fibrogenesis in experimental lung fibrosis by Thomas J. Harr, Nikesh Gupta, Babita Rahar, Kristen Stott, Yadira Medina-Guevara, Metti K. Gari, Angie T. Oler, Ivy Sohee McDermott, Hye Jin Lee, Morteza Rasoulianboroujeni, Ashley M. Weichmann, Amir Forati, Kelsey Holbert, Trevor S. Langel, Kade W. Coulter, Brian M. Burkel, Bianca R. Tomasini-Johansson, Suzanne M. Ponik, Jonathan W. Engle, Reinier Hernandez, Glen S. Kwon, Nathan Sandbo, Ksenija Bernau

“…Abstract Progressive forms of interstitial lung diseases, including idiopathic pulmonary fibrosis (IPF), are deadly disorders lacking non-invasive biomarkers for assessment of early disease activity, which presents a major obstacle in disease management. Excessive extracellular matrix (ECM) deposition is a hallmark of these disorders, with fibronectin being an abundant ECM glycoprotein that is highly upregulated in early fibrosis and serves as a scaffold for the deposition of other matrix proteins. …”
Get full text

Differentially expressed microRNAs in pre-transplant lung biopsies target immune checkpoint proteins and can predict primary graft dysfunction in lung transplantation by Vitale Miceli, Pia Ferrigno, Claudio Centi, Claudia Carcione, Gioacchin Iannolo, Valentina Agnese, Giovanna Lo Iacono, Rosa Liotta, Pier Giulio Conaldi, Massimo Pinzani, Lavinia De Monte, Alessandro Bertani

“…Additionally, the use of compounds that can modulate the function of these molecules could be evaluated for the management of LTx patients.…”
Get full text

Effect of Dam Emplacement and Water Level Changes on Sublacustrine Geomorphology and Recent Sedimentation in Jackson Lake, Grand Teton National Park (Wyoming, United States) by Michael M. McGlue, John R. Dilworth, Hillary L. Johnson, Samuel J. Whitehead, J. Ryan Thigpen, Kevin M. Yeager, Edward W. Woolery, Summer J. Brown, Sarah E. Johnson, Cooper S. Cearley, Gillian M. Clark, T. Spencer Dixon, Ryan C. Goldsby, Autumn L. Helfrich, Bailee N. Hodelka, Edward L. Lo, Leandro Domingos-Luz, Nicholas E. Powell, Giliane G. Rasbold, William R. Swanger

“…Results from this study illustrate the influence of dam installation on sublacustrine geomorphology and sedimentation, which has implications for lake management and ecosystem services. Further, this study demonstrates that Jackson Lake contains an expanded, untapped sedimentary archive recording environmental changes in the American West.…”
Get full text

Therapeutic effects of composite probiotics derived from fermented camel milk on metabolic dysregulation and intestinal barrier integrity in type 2 diabetes rats by Tabusi Manaer, Tabusi Manaer, Tabusi Manaer, Tabusi Manaer, Jialehasibieke Sailike, Xin Sun, Baheban Yeerjiang, Baheban Yeerjiang, Baheban Yeerjiang, Baheban Yeerjiang, Xinhua Nabi, Xinhua Nabi, Xinhua Nabi, Xinhua Nabi

“…These findings highlight the therapeutic potential of CPCM in T2DM management and probiotics’ role in metabolic health.…”
Get full text

Minimal Invasive Versus Open Surgery for Colorectal Liver Metastases: A Multicenter German StuDoQ|Liver Registry-Based Cohort Analysis in Germany by Simon Moosburner, MD, Chiara Kettler, Karl H. Hillebrandt, MD, Moritz Blank, Hannes Freitag, Sebastian Knitter, MD, Felix Krenzien, MD, Nora Nevermann, MD, Igor M. Sauer, MD, Dominik P. Modest, MD, Georg Lurje, MD, Robert Öllinger, MD, Wenzel Schöning, MD, Jens Werner, MD, Maximilian Schmeding, MD, Johann Pratschke, MD, Nathanael Raschzok, MD, members of StuDoQ|Liver of Deutsche Gesellschaft für Allgemein- und Viszeralchirurgie/StuDoQ

“…Retrospective cohort study using the prospectively recorded German Quality management registry for liver surgery. Propensity-score matching was performed to account for variance in the extent of resection and patient demographics. …”
Get full text

Multiparametric MRI along with machine learning predicts prognosis and treatment response in pediatric low-grade glioma by Anahita Fathi Kazerooni, Adam Kraya, Komal S. Rathi, Meen Chul Kim, Arastoo Vossough, Nastaran Khalili, Ariana M. Familiar, Deep Gandhi, Neda Khalili, Varun Kesherwani, Debanjan Haldar, Hannah Anderson, Run Jin, Aria Mahtabfar, Sina Bagheri, Yiran Guo, Qi Li, Xiaoyan Huang, Yuankun Zhu, Alex Sickler, Matthew R. Lueder, Saksham Phul, Mateusz Koptyra, Phillip B. Storm, Jeffrey B. Ware, Yuanquan Song, Christos Davatzikos, Jessica B. Foster, Sabine Mueller, Michael J. Fisher, Adam C. Resnick, Ali Nabavizadeh

“…Early prediction of treatment responsiveness and suitability for immunotherapy has the potential to improve clinical management and outcomes. Here, we present a radiogenomic analysis of pLGGs, integrating MRI and RNA sequencing data. …”
Get full text

H. pylori-Associated Gastritis, Gastritis after H. pylori Eradication and H. pylori-Negative Gastritis: Algorithm of Diagnosis and Treatment (Literature Review and Resolution of... by V. T. Ivashkin, I. V. Maev, T. L. Lapina, Yu. A. Kucheryavyy, S. R. Abdulkhakov, O. P. Alekseeva, S. A. Alekseenko, D. N. Andreev, I. G. Bakulin, N. V. Bakulina, D. S. Bordin, Z. M. Galeeva, N. N. Dekhnich, N. V. Korochanskaya, R. O. Kuvaev, M. A. Livzan, M. F. Osipenko, S. S. Pirogov, V. I. Simanenkov, O. A. Storonova, A. S. Tertychnyy, A. S. Trukhmanov, Yu. P. Uspenskiy, I. B. Khlynov, V. V. Tsukanov

“…Aim: to provide the basic points of the Expert Panel of the Russian Gastroenterological Association with discussion of measures to improve diagnostics, treatment and management of chronic gastritis patients.Key points. …”
Get full text

Early and high-volume administration of sodium bicarbonate in sepsis-associated acute kidney injury in patients with malignancies, during continuous renal replacement therapy by Lamei Ouyang, Yin Pan, Ya-Fei Wu, Qiang Tang, Dao-Feng Wang, Ning Lou

“…The goal is to provide valuable clinical data for the management of cancer patients with sepsis-associated acute kidney injury (SAKI).Materials and methods A retrospective study was performed on 88 patients who were admitted to the ICU and received continuous renal replacement therapy (CRRT) for acute renal failure secondary to sepsis at the Cancer Center of Sun Yat-sen University from March 2010 to October 2021. …”
Get full text