Compassionate Use of Omadacycline in a Down Syndrome Pre-Schooler With Critically Ill Atypical Pneumonia Caused by Macrolide-Resistant Mycoplasma Pneumoniae by Wu D, Xie FJ, Wang YJ, Jiang XH, Zhang GL, Zhang H, Zhu YC, Zhang Y, Tang YJ, Lin YL, Xu JX, Zhang JN, Liu BW, Kang K, Gao Y

“…The superior efficacy and safety of OMC in the management of critically ill atypical pneumonia caused by macrolide-resistant MP were comprehensively documented in this Down syndrome pre-schooler, which merits future well-designed studies to validate our findings, enhance understanding of the features of OMC, and further expand its clinical application in preschool-aged patients.Keywords: omadacycline, pre-schooler, down syndrome, macrolide-resistant mycoplasma pneumoniae, atypical pneumonia, targeted next generation sequencing, aetiological identification, antimicrobial resistance gene detection…”
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Factors That Affect the Sensitivity of Imaging Modalities in Primary Hyperparathyroidism by Minting Zhu, Yang He, Tingting Liu, Bei Tao, Weiwei Zhan, Yifan Zhang, Jing Xie, Xi Chen, Hongyan Zhao, Lihao Sun, Jianmin Liu

“…Exploring the factors that affect the sensitivity of these imaging modalities is important for the surgical management of PHPT patients. Methods. Clinical data of 352 PHPT patients hospitalized in our center from January 2011 to December 2015 were retrospectively collected to evaluate the sensitivity of 3 imaging modalities in the preoperative localization of parathyroid lesions. …”
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Comparison of the mid-infrared spectra and prediction equations developed from morning and evening milk samples from twice-a-day milked dairy cows by M. Frizzarin, E. Hayes, A. Casa, D.P. Berry

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Gender Analysis, Milk Value Chain, Kabale Uganda. Kabale: Kabale University. by Tugume, Samuel

“…Encourage women's groups for collective ownership and management of breeding stock. There is a need to Invest in infrastructure to reduce women's workload and free up their time for dairy activities. …”
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Estimation of inelastic skeletal storativity based on SAR-derived land subsidence and groundwater variation in Beijing Plain, China by Chenxia Li, Yanbing Wang, Jie Yu, Huili Gong, Xiaojuan Li, Xiyue Yang, Haowen Cheng, Xiaohuan Li, Kemiao Shao

“…The Si estimated in the study area can be utilized to accurately deduce the regional water level shifts, thereby aiding in the efficient and sustainable management of groundwater resources.…”
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Characteristics and quality of biofloc in vannamei shrimp culture with different carbon sources by Muhammad Faris Allam, Julie Ekasari, Ichsan Achmad Fauzi, Wiyoto Wiyoto

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Presentations on How to Finance Iran's Higher Education Based on the Global Study Model by Ehsan Ehteshamnejad, Mehdi Pakzad Bonab, Mehdi Ramezani

“…The dual financing makes university managers to simultaneously implement reports on maintaining and improving the academic level of the university, along with increasing the amount of wealth creation. …”
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Field Deployment of a Mobile Biosafety Laboratory Reveals the Co-Circulation of Dengue Viruses Serotype 1 and Serotype 2 in Louga City, Senegal, 2017 by Idrissa Dieng, Maryam Diarra, Moussa Moïse Diagne, Martin Faye, Marie Henriette Dior Ndione, Yamar Ba, Mamadou Diop, El Hadji Ndiaye, Paolo Marinho de Andrade Zanotto, Boly Diop, Mamadou Ndiaye, Abdoulaye Bousso, Ndongo Dia, Mawlouth Diallo, Aliou Barry, Gamou Fall, Cheikh Loucoubar, Amadou Alpha Sall, Ousmane Faye, Oumar Faye

“…Interestingly, it also proved the reliability and usefulness of the MBS-Lab for expedient outbreak response at the point of need, which allows early cases management.…”
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Tax on Vacant Houses and Housing Price Bubble in Shiraz by Sara Parang, zahra dehghan shabani, Ebrahim Hadian, Ali Asgary

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Spot Versus 24-Hour Urine Osmolality Measurement in Autosomal Dominant Polycystic Kidney Disease: A Diagnostic Test Study by Ayub Akbari, Sriram Sriperumbuduri, Shreepryia Mangalgi, Vijay Joshi, Manish Sood, Amos Buh, Mohan Biyani, Christopher McCudden, Gregory L. Hundemer, Pierre Antoine Brown

“…The method employed to determine urine osmolality may impact clinical decision-making in the management of patients with adult polycystic kidney disease.…”
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GIS-based modeling and analytical approaches for groundwater quality suitability for different purposes in the Egyptian Nile Valley, a case study in Wadi Qena by Hanaa A. Megahed, Abd El-Hay A. Farrag, Amira A. Mohamed, Mahmoud H. Darwish, Mohamed A. E. AbdelRahman, Heba El-Bagoury, Paola D’Antonio, Antonio Scopa, Mansour A. A. Saad

“…The study lists corrective measures to improve groundwater quality using monitoring systems, efficient irrigation techniques, localized desalination, artificial recharge projects, stricter waste management and agricultural policies that will minimize sources of contamination. …”
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Agro-Ecological Assessment of Lands in Behshahr County for Lentil (Lens culinaris Medik.) Cultivation by Karim Reyahi, Hossein Kazemi, Afshin Soltani, Fardin Sadeghzadeh

“…However, in many cases, agricultural systems have low production, which is related to management issues. Also, the climatic capabilities of the regions are sometimes effective as a limiting factor in crop production. …”
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SHoes for Adolescent PatEllofemoral pain: study protocol for the SHAPE Australian community-based, randomised clinical trial by Kim L Bennell, Kade L Paterson, Rana S Hinman, Jo-Anne Manski-Nankervis, Adam Bryant, Karen Elaine Lamb, Peixuan Li, Sam Shearer, Anurika P De Silva

“…‘Minimalist’ shoes can reduce patellofemoral joint forces in adults; and may therefore be a promising low burden management approach for patellofemoral pain. This article outlines the protocol for a randomised clinical trial (RCT) that aims to determine if minimalist footwear improves pain, function and other symptoms compared with motion control shoes, in adolescents with patellofemoral pain.Methods and analysis This is a 3-month, pragmatic, two-arm parallel group, comparative effectiveness, superiority RCT conducted in Melbourne, Australia. …”
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Prevalence of anaemia and the associated factors among hospitalised people living with HIV receiving antiretroviral therapy in Southwest China: a cross-sectional study by Jie Yuan, Hai Long, Min Liu, Juan He, Jue Liu, Yu Wu, Wenzhan Jing, Min Du, Manna Zhang, Yaping Wang, Su Song, Siqi Liu, Guiying Cao, Yuedong Liang, Xiaoxin Xie, Yanhua Fu

“…Determination of anaemia predictors, early detection and timely management of anaemia are crucial to prevent anaemia progression.…”
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mTOR downregulation promotes anti-inflammatory responses via the CCL3-CCR5 axis in hypoxic retinopathy by Tae Kwon Moon, Im Kyeung Kang, Kyoung Jin Lee, Ji Hyun Kim, Hee Jong Kim, A. Reum Han, Ha-Na Woo, Joo Yong Lee, Jun-Sub Choi, Keerang Park, Heuiran Lee

“…Notably, the virus lowered CCL3 expression in Müller cells and reduced the presence of CCR5-positive microglia in vivo, indicating its effectiveness in targeted inflammation management via the CCL3-CCR5 pathway. These findings thus highlight the potential of AAV2-shmTOR to exert anti-inflammatory effects by influencing the mTOR and subsequent CCL3-CCR5 pathways in hypoxic retinopathies, presenting a novel therapeutic approach for retinal diseases marked by hypoxia-driven inflammation.…”
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CAM/TMA-DPH as a promising alternative to SYTO9/PI for cell viability assessment in bacterial biofilms by Tinatini Tchatchiashvili, Tinatini Tchatchiashvili, Mateusz Jundzill, Mateusz Jundzill, Mike Marquet, Kamran A. Mirza, Kamran A. Mirza, Mathias W. Pletz, Mathias W. Pletz, Oliwia Makarewicz, Oliwia Makarewicz, Lara Thieme, Lara Thieme

“…The consistency of CAM/TMA-DPH staining across different bacterial species underscores its potential to advance studies on biofilm and contribute to the development of more effective anti-biofilm treatments, which is essential for clinical management of biofilm-associated infections.…”
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Unravelling the prognostic and operative role of intratumoural microbiota in non‐small cell lung cancer: Insights from 16S rRNA and RNA sequencing by Fuling Mao, Zixuan Hu, Ruifeng Shi, Hongbing Zhang, Zihe Zhang, Yongwen Li, Xuanguang Li, Penghu Gao, Jinhui Li, Minghui Liu, Hongyu Liu, Jun Chen

“…Furthermore, Peptococcus may be significant in adverse NSCLC prognoses and serve as a potential biomarker for patient management and cancer screening. Key points Four phyla, five classes, nine orders, 17 families and 36 genera have been found associated with NSCLC prognosis. …”
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Can invasive interventions be avoided with a holistic swallowing therapy program in older patients in intensive care units: percutaneous endoscopic gastrostomy tubes or oral intake... by Çağla Eliküçük, Fatma Esen Aydinli, Nazan Has Selmi, Cansu Uzunoğlu, Murathan Köksal, Volkan Öter, Belgin Akan, Erdal Birol Bostanci, Güldeniz Argun

“…Significant gaps exist regarding the evidence for the evaluation and management of dysphagia in older patients. This study aimed to diagnose swallowing disorders and highlight the importance of swallowing therapy in older patients in intensive care units (ICUs).Materials and methodsTwenty-five older patients (12 men, 13 women, mean age 67.22 ± 24.03 years) hospitalized in the ICUs with complaints of dysphagia were analyzed prospectively. …”
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Associations of fasting plasma glucose and glycosylated hemoglobin levels at less than 24 weeks of gestation with hypertensive disorders of pregnancy: the BOSHI study by Seiya Izumi, Noriyuki Iwama, Hirotaka Hamada, Taku Obara, Mami Ishikuro, Michihiro Satoh, Takahisa Murakami, Masatoshi Saito, Takayoshi Ohkubo, Takashi Sugiyama, Shinichi Kuriyama, Nobuo Yaegashi, Kazuhiko Hoshi, Yutaka Imai, Hirohito Metoki, the BOSHI Study Group

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The impact of integrated genomic analysis on molecular classifications and prognostic risk stratification in endometrial cancer: a Chinese experience by Qian Zheng, Qian Zheng, Qian Zheng, Di Shao, Jin Shu, Jin Shu, Jin Shu, Qin Zhang, Qin Zhang, Qin Zhang, Min Huang, Dong Wang, Dong Wang, Dong Wang, Dongling Zou, Dongling Zou, Dongling Zou

“…Conclusively, large-scale NGS has revolutionized EC management by facilitating rapid molecular subtype identification, guiding tailored adjuvant therapies, targeted treatments, and immunotherapies, and efficiently screening for Lynch syndrome, thereby significantly improving patient outcomes.…”
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