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141
Linear and structural stability of a cell division process model
Published 2006-01-01“…The paper investigates the linear stability of mammalian physiology time-delayed flow for three distinct cases (normal cell cycle, a neoplasmic cell cycle, and multiple cell arrest states), for the Dirac, uniform, and exponential distributions. …”
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142
Stage-specific function of sphingolipid synthases in African trypanosomes
Published 2025-02-01“…IPC synthesis occurs exclusively in the procyclic insect stage (PCF), EPC is limited to the mammalian bloodstream form (BSF), and SM is synthesized throughout the life cycle. …”
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143
Loss of LRRK2 activity induces cytoskeleton defects and oxidative stress during porcine oocyte maturation
Published 2025-01-01“…However, the roles of LRRK2 during mammalian oocyte maturation are still largely unclear. …”
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144
Antimicrobial resistance in wild game mammals: a glimpse into the contamination of wild habitats in a systematic review and meta-analysis
Published 2025-01-01“…Methods This study aimed to describe the prevalence of antibiotic-resistant bacteria in mammalian wild game, following the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines. …”
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145
The Central Role and Possible Mechanisms of Bacterial DNAs in Sepsis Development
Published 2020-01-01“…Bacterial DNAs are different from mammalian DNAs; the latter are heavily methylated. …”
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146
Near-infrared fluorogenic RNA for in vivo imaging and sensing
Published 2025-01-01“…One of these fluorophores, DFQL-1T, exhibits photostable NIR fluorescence when bound to Squash, enabling RNA visualization in living mammalian cells and mice. With Squash:DFQL-1T complexes, we generate RNA-based sensors for detecting non-coding RNAs and small molecule targets in living mammalian cells and in mice. …”
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147
Mitochondrial Dynamics: Functional Link with Apoptosis
Published 2012-01-01“…In this paper, we briefly summarize current knowledge of the role of mitochondrial dynamics in apoptosis and cell pathophysiology in mammalian cells.…”
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148
Visualization of the Dynamics of Gene Expression in the Living Mouse
Published 2004-01-01“…Using this technology, we have determined the rate of gene induction and repression, the level of target gene activity in response to different doses of inducer, and the schedule of induction during early embryogenesis of both the endogenous and the experimentally manipulated programs of mammalian gene expression associated with the HD/Hdh locus. …”
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149
Influenza A virus in dairy cattle: infection biology and potential mammary gland-targeted vaccines
Published 2025-01-01“…This review explores general aspects of influenza A virus (IAV) biology, its interactions with mammalian hosts, and discusses the key considerations for developing vaccines to prevent or curtail IAV infection in the bovine mammary gland and its spread through milk.…”
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150
Anaerobic fungi: Neocallimastigomycota
Published 2010-12-01“…Next-generation sequencing has also allowed more detailed investigation of the ecology and diversity of these fungi, and it is apparent that several new taxa beyond the six genera already named exist within the digestive tracts of mammalian herbivores, with others potentially inhabiting other anaerobic niches. …”
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151
Characterization of a chitinase from Trichinella spiralis and its immunomodulatory effects on allergic airway inflammation in mice
Published 2025-01-01“…Methods Recombinant Trichinella spiralis chitinase (rTs-chit) was expressed in Escherichia coli BL21, and its structural homology to murine acidic mammalian chitinase (AMCase) was comprehensively analyzed. …”
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152
Genotoxicity Revaluation of Three Commercial Nitroheterocyclic Drugs: Nifurtimox, Benznidazole, and Metronidazole
Published 2009-01-01“…The lack of effects on mammalian cells for MTZ is confirmed also in MN assay whereas MN induction is observed for NFX and BNZ. …”
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153
Cardiovascular Development and the Colonizing Cardiac Neural Crest Lineage
Published 2007-01-01“…Although it is well established that transgenic manipulation of mammalian neural crest-related gene expression and microsurgical removal of premigratory chicken and Xenopus embryonic cardiac neural crest progenitors results in a wide spectrum of both structural and functional congenital heart defects, the actual functional mechanism of the cardiac neural crest cells within the heart is poorly understood. …”
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154
Primitive to visceral endoderm maturation is essential for mouse epiblast survival beyond implantation
Published 2025-01-01“…These findings offer new insights into the molecular regulation of early mammalian development.…”
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155
BRCA1 is involved in sustaining rapid antler growth possibly via balancing of the p53/endoplasmic reticulum stress signaling pathway
Published 2025-01-01“…Interestingly deer antlers, arguably the fastest regenerating mammalian tissue, have not been reported, thus far, to grow malignant tumors. …”
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156
The concepts of Ludwik Fleck and their application to the eukaryotic cell cycle
Published 2017-12-01“…These are (a) the G1-phase restriction point as a regulatory element of the mammalian cell cycle, (b) the Rate Change Point proposed to exist in fission yeast, and (c) the proposal that a large number of genes are expressed in a cell-cycle-dependent manner. …”
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157
Effector Caspases and Leukemia
Published 2011-01-01“…Caspases, a family of aspartate-specific cysteine proteases, play a major role in apoptosis and a variety of physiological and pathological processes. Fourteen mammalian caspases have been identified and can be divided into two groups: inflammatory caspases and apoptotic caspases. …”
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158
Functions of Fasciculation and Elongation Protein Zeta-1 (FEZ1) in the Brain
Published 2010-01-01“…Fasciculation and elongation protein zeta-1 (FEZ1) is a mammalian ortholog of the Caenorhabditis elegans UNC-76 protein that possesses four coiled-coil domains and a nuclear localization signal. …”
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159
Alternative Cell Death Pathways and Cell Metabolism
Published 2013-01-01“…While necroptosis has for long been viewed as an accidental mode of cell death triggered by physical or chemical damage, it has become clear over the last years that necroptosis can also represent a programmed form of cell death in mammalian cells. Key discoveries in the field of cell death research, including the identification of critical components of the necroptotic machinery, led to a revised concept of cell death signaling programs. …”
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160
The Role of Targeted Therapy in Metastatic Renal Cell Carcinoma
Published 2007-01-01“…The most clinically developed targeted therapies in advanced RCC are those that target the vascular endothelial growth factor (VEGF) ligand or receptor (VEGFR) and therapy directed against the mammalian target of rapamycin (mTOR). Sutent and sorafenib are orally available inhibitors of the VEGFR and platelet derived growth factor receptor (PDGFR). …”
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