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201
How Hippo Signaling Pathway Modulates Cardiovascular Development and Diseases
Published 2018-01-01“…The canonical Hippo tumor suppressor pathway in mammalian cells is primarily composed of the MST1/2-SAV1-LATS1/2-MOB1-YAP/TAZ cascade. …”
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202
Assessment of comminution capacity related to molar intercuspation in catarrhines using a chewing simulator
Published 2022-08-01“…Mammalian molars play a central role during chewing, or food comminution, through cyclic dental occlusion. …”
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203
1987-2017 : Regard sur l’évolution de l’histoire des origines
Published 2018-03-01“…The reconstructions of environments largely based on palaeobiota, are now supplemented by geochemical studies of the enamel of mammalian teeth (reconstruction of diets), but also of the sediments (highlighting phases of aridity, by example). …”
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204
The Effect of Decreasing Temperature on Arthropod Diversity and Abundance in Horse Dung Decomposition Communities of Southeastern Massachusetts
Published 2012-01-01“…Dung from large mammalian herbivores provides a concentrated food resource, rich in bacteria, nitrogen, and many forms of carbon that support a diverse community of arthropods. …”
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205
Muscular TOR knockdown and endurance exercise ameliorate high salt and age-related skeletal muscle degradation by activating the MTOR-mediated pathway.
Published 2025-01-01“…Therefore, the current findings confirm that the muscle TOR gene plays an important role in endurance exercise against HSD-induced age-related skeletal muscle degeneration, as it determines the activity of the mammalian target of rapamycin(MTOR)/SIR2/PGC-1α and MTOR/ATG2/PGC-1α pathways in skeletal muscle.…”
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206
Comprehensive Insight of Neurodegenerative Diseases and The Role of Neurotoxin Agents — Glutamate
Published 2020-04-01“…The increased concentration of extracellular glutamate has been reported to play a key role in most of the neurodegenerative diseases, such as Parkinson’s disease and Alzheimer’s disease, even though its importance as an amino acid neurotransmitter in mammalian. Glutamate toxicity, which can be caused by excessive intake of monosodium glutamate (MSG), is the major contributor to pathological neuronal cell death. …”
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207
Glutathione: A Key Regulator of Extracellular Matrix and Cell Death in Intervertebral Disc Degeneration
Published 2024-01-01“…GSH is one of the most abundant thiol antioxidants in mammalian cells, which functions directly and indirectly by scavenging peroxides through the GSH redox system. …”
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208
Cryo-electron tomography pipeline for plasma membranes
Published 2025-01-01“…The pipeline provides efficient, distributable, low-cost sample preparation and enables targeted structural studies of identified proteins at the plasma membrane of mammalian cells.…”
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209
Novel Arsenic Nanoparticles Are More Effective and Less Toxic than As (III) to Inhibit Extracellular and Intracellular Proliferation of Leishmania donovani
Published 2014-01-01“…Arsenic (III) at a relatively higher concentration (30 μg/mL) has been shown to have antileishmanial activity, but this concentration is reported to be toxic in several experimental mammalian systems. Nanosized metal (0) particles have been shown to be more effective than their higher oxidation state forms. …”
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210
Anticholinesterase Toxicity and Oxidative Stress
Published 2006-01-01“…They exert their toxicity in mammalian system primarily by virtue of acetylcholinesterase (AChE) inhibition at the synapses and neuromuscular junctions, leading into the signs of hypercholinergic preponderance. …”
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211
Research Progress on Biomaterials for Spinal Cord Repair
Published 2025-02-01“…Unfortunately, the adult mammalian spinal cord displays little regenerative capacity after injury. …”
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212
INFORMATION SUPPORT OF RESEARCH ON TRANSCRIPTIONAL REGULATORY MECHANISMS: AN ONTOLOGICAL APPROACH
Published 2014-12-01“…The pilot version of the knowledge base on the transcriptional regulation of eukaryotic genes includes: (1) description of basic terms related to transcription regulation and relationships between them; (2) hierarchical classification of transcription regulators; (3) classification of phases and steps of transcription; (4) a database of transcriptional regulators of three mammalian species (human, mouse, and rat); and (5) dictionaries for molecular processes involved in transcriptional regulation. …”
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213
Potential Role of Gene Regulator NFAT5 in the Pathogenesis of Diabetes Mellitus
Published 2020-01-01“…Nuclear factor of activated T cells 5 (NFAT5), a Rel/nuclear factor- (NF-) κB family member, is the only known gene regulator of the mammalian adaptive response to osmotic stress. Exposure to elevated glucose increases the expression and nuclear translocation of NFAT5, as well as NFAT5-driven transcriptional activity in vivo and in vitro. …”
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214
Chronic Fluoxetine Treatment Suppresses Plasticity (Long-Term Potentiation) in the Mature Rodent Primary Auditory Cortex In Vivo
Published 2014-01-01“…We conclude that chronic fluoxetine treatment fails to enhance LTP in the mature rodent thalamocortical auditory system, results that bring into question the notion that SSRIs act as general facilitators of synaptic plasticity in the mammalian forebrain.…”
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215
Observations of amphibian, reptile and some mammal species in the area of Šaleška jezera near Velenje during the 2015–2017 period
Published 2018-06-01“…New records on the occurrence of 9 amphibian, 7 reptilian and 9 mammalian species were made in the region during our field work carried out from 2015 to 2017. …”
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216
The spatial buildup of nonlinear compression in the cochlea
Published 2025-01-01“…In the mammalian cochlea, the transduction from vibrations to inner hair cell receptor currents is preceded by a stage of mechanical pre-processing that involves a rapid, strongly nonlinear compression. …”
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217
Single-cell RNA sequencing reveals the heterogeneity and interactions of immune cells and Müller glia during zebrafish retina regeneration
Published 2025-12-01“…Our study reveals the cell heterogeneity and crosstalk of immune cells and MG in zebrafish retinal repair, and may provide valuable insights into future mammalian retina regeneration.…”
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218
Pathogenic and therapeutic roles of extracellular vesicles in sepsis
Published 2025-02-01“…Extracellular vesicles (EVs) released by mammalian cells and bacteria have been shown to play important roles in intercellular communication and progression of various diseases. …”
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219
Differential Toxicity of DNA Adducts of Mitomycin C
Published 2010-01-01“…This review focuses on differential biological effects of individual adducts in various mammalian cell cultures, observed in the authors' laboratories. …”
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220
Strategies for Regenerating Striatal Neurons in the Adult Brain by Using Endogenous Neural Stem Cells
Published 2011-01-01“…However, recent studies have shown that new neurons are continuously generated by endogenous neural stem cells in the subventricular zone (SVZ) of the adult mammalian brain, including the human brain. Because some of these new neurons migrate to the injured striatum and differentiate into mature neurons, such new neurons may be able to replace degenerated neurons and improve or repair neurological deficits. …”
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