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181
Bacteriophages: Uncharacterized and Dynamic Regulators of the Immune System
Published 2019-01-01“…Despite tremendous advances in our comprehension of how the gut microbiota is involved in human health and interacts with the mammalian immune system, most studies are incomplete as they typically do not consider bacteriophages. …”
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182
LncRNAs: New Players in Apoptosis Control
Published 2014-01-01“…The discovery that the mammalian genome is largely transcribed and that almost half of the polyadenylated RNAs is composed of noncoding RNAs has attracted the attention of the scientific community. …”
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183
AhR governs lipid metabolism: the role of gut microbiota
Published 2025-01-01“…The Aryl Hydrocarbon Receptor (AhR) is widely present in mammalian bodies, showing high affinity for various exogenous substances such as polycyclic aromatic hydrocarbons (PAHs) and coumarin. …”
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184
From Prion Diseases to Prion-Like Propagation Mechanisms of Neurodegenerative Diseases
Published 2013-01-01“…We will then describe the recent reports on mammalian synthetic prions and recombinant prions that strongly support the protein-only hypothesis. …”
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185
CD4 expression controls epidermal stem cell balance
Published 2025-02-01“…Abstract The balance of stem cell populations is essential for the maintenance, renewal, and repair of the mammalian epidermis. Here, we report that CD4, which is a typical marker of helper T cells, monocytes, macrophages, and dendritic cells, is also expressed on murine K5+ keratinocytes. …”
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186
Fluo-Cast-Bright: a deep learning pipeline for the non-invasive prediction of chromatin structure and developmental potential in live oocytes
Published 2025-01-01“…Abstract In mammalian oocytes, large-scale chromatin organization regulates transcription, nuclear architecture, and maintenance of chromosome stability in preparation for meiosis onset. …”
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187
IQUB mutation induces radial spoke 1 deficiency causing asthenozoospermia with normal sperm morphology in humans and mice
Published 2025-01-01“…Protein mass spectrometry, western blotting, and bioinformatic analyses were performed to identify critical components of mammalian RS1 to model its structure and explore the pathological mechanism of IQUB deficiency. …”
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188
Cardiac repair using regenerating neonatal heart tissue-derived extracellular vesicles
Published 2025-02-01“…Abstract Neonatal mammalian hearts are capable of regenerating by inducing cardiomyocyte proliferation after injury. …”
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189
A Heating and Cooling Stage With Fast Temporal Control for Biological Applications
Published 2024-01-01“…We envision that this device could benefit the communities using model and non-model organisms with physiological temperatures different from typical mammalian cell culture incubation in biomedical research.…”
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190
Genes and light: many years later
Published 2017-07-01“…Belyaev and discusses his studies of photoperiodic changes on mammalian reproduction and embryonic development in the realm of modern data. …”
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191
Reversion of Hormone Treatment Resistance with the Addition of an mTOR Inhibitor in Endometrial Stromal Sarcoma
Published 2014-01-01“…Hormone treatment is widely used in ESS but primary or acquired resistance is common. The mammalian target of rapamycin (mTOR) pathway has been suggested to play a key role in the mechanisms of hormone resistance. …”
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192
The Role of mTOR Inhibitors in Liver Transplantation: Reviewing the Evidence
Published 2014-01-01“…Clearly there is a need for better immunosuppressive agents that maintain similar rates of efficacy and renal function whilst minimizing adverse effects. The mammalian target of rapamycin (mTOR) inhibitors with a mechanism of action that is different from other immunosuppressive agents has the potential to address some of these issues. …”
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193
Protocol for the purification and analysis of nuclear UFMylated proteins
Published 2025-03-01“…Here, we present a technique to isolate nuclei and purify UFMylated proteins under denaturing non-reducing conditions from commonly used mammalian cell line models such as hTERT-RPE1, HEK293, U2OS, and HCT116 cells. …”
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194
Conditional Inactivation of HIF-1 Using Intrabodies
Published 2008-01-01“…Conditional expression of HIF intrabodies in mammalian cells interfered with binding to pVHL and inhibited hypoxia induced activation of endogenous target genes. …”
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195
Adult Hippocampal Neurogenesis in Alzheimer’s Disease: An Overview of Human and Animal Studies with Implications for Therapeutic Perspectives Aimed at Memory Recovery
Published 2022-01-01“…The mammalian hippocampal dentate gyrus is a niche for adult neurogenesis from neural stem cells. …”
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196
Pathway and molecular mechanisms for malachite green biodegradation in Exiguobacterium sp. MG2.
Published 2012-01-01“…However, due to its negative impact on the environment and carcinogenic effects to mammalian cells, there is a significant interest in developing microbial agents to degrade this type of recalcitrant molecules. …”
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197
Axon regeneration: an issue of translation
Published 2024-12-01“…In the mammalian central nervous system (CNS), adult neurons fail to regenerate spontaneously upon axon injury, which leads to a permanent and irreversible loss of neuronal functions. …”
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198
Prediction of hemolytic peptides and their hemolytic concentration
Published 2025-02-01“…These models train on 1926 peptides with experimentally determined HC50 against mammalian RBCs. Analysis indicates that hydrophobic and positively charged residues were associated with higher hemolytic activity. …”
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199
Heme Oxygenase-1: A Critical Link between Iron Metabolism, Erythropoiesis, and Development
Published 2011-01-01“…The first mature cells to arise in the developing mammalian embryo belong to the erythroid lineage. This highlights the immediacy of the need for red blood cells during embryogenesis and for survival. …”
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200
Distinct roles for intra- and extracellular siderophores during Aspergillus fumigatus infection.
Published 2007-09-01“…Our findings reveal distinct cellular and disease-related roles for intra- and extracellular siderophores during mammalian Aspergillus infection.…”
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