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381
An Assay System for Plate-based Detection of Endogenous Peptide:N-glycanase/NGLY1 Activity Using A Fluorescence-based Probe
Published 2025-01-01“…Cytosolic peptide: N-glycanase (PNGase/NGLY1 in mammals), an amidase classified under EC:3.5.1.52, is a highly conserved enzyme across eukaryotes that catalyzes the removal of N-glycans from glycoproteins, converting N-glycosylated asparagine residues into aspartic acid. …”
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382
Immunofluorescence for Detection of TOR Kinase Activity In Situ in Photosynthetic Organisms
Published 2024-12-01“…However, at the tissue/cell-specific level, there is a huge gap in plants due to the lack of alternative techniques for the evaluation of TOR activity as there are for other organisms such as mammals. Here, we describe an in vivo protocol to detect S6K phosphorylation in tissues/cells of model photosynthetic organisms such as Arabidopsis thaliana and Chlamydomonas reinhardtii. …”
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383
Consistent individual positions within roosts in Spix’s disc-winged bats
Published 2023-11-01“…In social bats, we would expect a similar consistent arrangement for groups at roost-sites, which is where these mammals spend the largest portion of their lives. …”
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384
Impervious surface cover and number of restaurants shape diet variation in an urban carnivore
Published 2025-01-01“…The highest contributor to coyote diet overall was anthropogenic food followed by small mammals. The most frequently detected species were domestic chicken, pocket gopher (Thomomys bottae), domestic pig, and raccoon (Procyon lotor). …”
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385
Structure-activity relationship and in silico docking analysis of dicarboximide fungicides on 17β-hydroxysteroid dehydrogenase 1 of human, rat, and pig
Published 2025-01-01“…Dicarboximide fungicides, including captafol, captan, cyclohexylthiophthalimide, folpet, and procymidone, represent a distinct category of fungicides. 17β-Hydroxysteroid dehydrogenase 1 (17β-HSD1) catalyzes the conversion of estrone to estradiol in mammals. Yet, the impact of these fungicides on 17β-HSD1 activity remains unknown. …”
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386
Generation of transgenic chicken through ovarian injection
Published 2025-01-01“…Abstract Background Traditional DNA microinjection methods used in mammals are difficult to apply to avian species due to their unique reproductive characteristics. …”
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387
Frequency of Trypanosoma cruzi Infection in Synanthropic and Wild Rodents Captured in a Rural Community in Southeast of Mexico
Published 2018-01-01“…T. cruzi infect a great variety of domestic and wild mammals; rodents are considered one of the most important reservoirs of the parasite in the transmission cycles of T. cruzi. …”
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388
The Wildcat That Lives in Me: A Review on Free-Roaming Cats (<i>Felis catus</i>) in Brazil, Focusing on Research Priorities, Management, and Their Impacts on Cat Welfare
Published 2025-01-01“…In Australia, for example, cats are responsible for the decline in many vertebrate populations and extinction of several native mammals. However, in Brazil, few studies have explored either direct impacts of predation on wildlife, or other indirect impacts, such as competition for resources, niche overlap, hybridization, and disease transmission. …”
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389
Camel tick species distribution in Saudi Arabia and United Arab Emirates using MaxEnt modelling
Published 2024-08-01“…Ticks are important vectors and reservoirs of pathogens causing zoonotic diseases in camels and other livestock, rodents and other small mammals, birds and humans. Hyalomma dromedarii is the most abundant tick species in Saudi Arabia and United Arab Emirates (UAE) affecting primarily camels, and to a lesser extent, other livestock. …”
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390
Xenopus laevis neural stem progenitor cells exhibit a transient metabolic shift toward glycolysis during spinal cord regeneration
Published 2025-01-01“…Spinal cord injury (SCI) results in severe disruption of communication between the brain and body, causing motor, sensory, and autonomic dysfunctions. While SCI in mammals leads to permanent impairment due to limited regenerative capacity, certain non-mammalian species, such as Xenopus laevis larval stages, exhibit remarkable regenerative abilities. …”
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391
Molecular Modulation of Fetal Liver Hematopoietic Stem Cell Mobilization into Fetal Bone Marrow in Mice
Published 2020-01-01“…The current review holds great potential to deeply understand the molecular regulations of HSCs in the fetal liver and bone marrow in mammals, which will be helpful to efficiently expand HSCs in vitro.…”
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392
Maternal exposure to polystyrene nanoplastics during gestation and lactation caused fertility decline in female mouse offspring
Published 2025-01-01“…Overall, maternal exposure to PS-NPs induced profound and enduring effects on the reproductive functions of female offspring, raising critical alarms regarding the multigenerational reproductive toxicity risks associated with nanoplastic exposure in mammals.…”
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393
Functional Metaplasticity of Hippocampal Schaffer Collateral-CA1 Synapses Is Reversed in Chronically Epileptic Rats
Published 2017-01-01“…Spatial learning and associating spatial information with individual experience are crucial for rodents and higher mammals. Hence, studying the cellular and molecular cascades involved in the key mechanism of information storage in the brain, synaptic plasticity, has led to enormous knowledge in this field. …”
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394
Characterization and functional analysis of chicken hnRNP protein
Published 2025-03-01“…While the role of hnRNP proteins in modulating interferon signaling and virus replication in mammals has been extensively studied, the impact of chicken hnRNPs on innate immune response and Infectious Bursal Disease Virus (IBDV) replication remains largely unexplored. …”
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395
What ‘unexplored’ means: mapping regions with digitized natural history records to look for ‘biodiversity blindspots’
Published 2025-01-01“…We examined global records of accessible natural history voucher collections (with publicly available data and reliable locality data) for terrestrial and freshwater vascular plants, fungi, freshwater fishes, birds, mammals, and herpetofauna (amphibians and reptiles) and highlight areas of the world that would be considered undersampled and sometimes called ‘unexplored’ (i.e., have relatively low, or no evidence of, past sampling efforts) under typical Western-scientific descriptions. …”
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396
Mice with NOP2/sun RNA methyltransferase 5 deficiency die before reaching puberty due to fatal kidney damage
Published 2024-12-01“…However, our knowledge of the biological functions of NSUN5 in mammals is very limited. Therefore, in this study, we investigate the role of NSUN5 in mice.Methods In the present research, we built a mouse model (Nsun5-/-) using the CRISPR/Cas9 system to investigated the specific role of NSUN5.Results We observed that Nsun5-/- mice had a reduced body weight compared to wild-type mice. …”
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397
PRMT7: A Pivotal Arginine Methyltransferase in Stem Cells and Development
Published 2021-01-01“…To date, nine PRMT family members, namely, PRMT1, 2, 3, 4, 5, 6, 7, 8, and 9, have been identified in mammals. Among them, PRMT7 is a type III PRMT that can only catalyze the formation of monomethylarginine and plays pivotal roles in several kinds of stem cells. …”
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398
Three concepts: an academic ecologist’s view
Published 2024-12-01“…Anthropodependent biotic communities include not only agricultural plants, but also a full spectrum of organisms, from bacteria to mammals. It is pointed out that there is a contradiction between the idea of preserving biodiversity in ecosystems and the high productivity of certain significantly dominant populations. …”
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399
Effects of Selenium Supplement on B Lymphocyte Activity in Experimental Autoimmune Thyroiditis Rats
Published 2021-01-01“…Thyroid is the organ with the highest selenium content in mammals, and selenium is an essential micronutrient that has close relationship with thyroid autoimmunity. …”
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400
Individual differences in developmental trajectory leave a male polyphenic signature in bulb mite populations
Published 2023-12-01“…Instead, we suggest that juveniles mitigate their increased mortality risk by expediating ontogeny to forego the development of costly morphology and mature quicker but as a defenceless scrambler. If, like in mammals and birds where early-life stress effects are extensively studied, we account for such pre-adult viability selection in coldblooded species, it would allow us to (i) better characterise natural selection on trait development like male polyphenisms, (ii) understand how it can affect the response to other selections in adulthood, and (iii) understand how such trait dynamics influence, and are influenced by, population dynamics. …”
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