Unique Aspects of Cryptochrome in Chronobiology and Metabolism, Pancreatic β-Cell Dysfunction, and Regeneration: Research into Cysteine414-Alanine Mutant CRY1 by Satoshi Okano

“…CRYs play indispensable roles in the generation of circadian rhythm in mammals. Transgenic mice (Tg mice), ubiquitously expressing mouse CRY1 having a mutation in which cysteine414 (the zinc-binding site of CRY1) being replaced with alanine, display unique phenotypes in their circadian rhythms. …”
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Morphologic Examination of Ossicula Auditus in Different Ruminants by İsmail Demircioğlu, Funda Aksünger Karaavci

“…In addition, the bone that exists as os lenticulare in humans exists as processus lenticulare in most mammals. Objective To our knowledge, no in‐depth study has been published on the ossicula auditus of gazelles. …”
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Revisiting two hypotheses on the “domestication syndrome” in light of genomic data by A. S. Wilkins

“…Domesticated mammals of many different species share a set of physical and physiological traits that are not displayed by any of their wild progenitors. …”
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Renal Tubular Cells from Hibernating Squirrels are Protected against Cisplatin Induced Apoptosis by Swati Jain, Alkesh Jani

“…Hibernating 13-lined ground squirrels are characterized by tolerance of severe hypothermia and hypoperfusion during torpor, followed by periodic warm reperfusion during IBA, conditions which are lethal to nonhibernating mammals. The aim of the present study was to determine whether protection from apoptosis was specific to torpor arousal cycles during hibernation or will also apply to cisplatin treatment on squirrel renal tubular cells (RTECs) that were procured during hibernation. …”
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Human-Terrestrial Wildlife Conflict in Ethiopia: A Systematic Review by Getahun Shanko, Bekele Tona

“…The literature focused mainly on larger mammals, led by Ethiopian authors, and excluded the social dimensions of HWC. …”
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Animal Models of Diabetic Retinopathy: Summary and Comparison by Angela Ka Wai Lai, Amy C. Y. Lo

“…The advantages and disadvantages of using different animals, ranging from zebrafish, rodents to other higher-order mammals, are also discussed. Until now, there is no single model that displays all the clinical features of DR as seen in human. …”
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Population structure of Clinostomum complanatum (Trematoda: Digenea) with new data on haplotype diversity of flukes from Slovakia and Italy by Juhásová Ľudmila, Bazsalovicsová Eva Čisovská, Caffara Monica, Radačovská Alžbeta, Gustinelli Andrea, Dinisová Lucia, Syrota Yaroslav, Králová-Hromadová Ivica

“…The fluke Clinostomum complanatum, a parasite of piscivorous birds, but also reptiles and rarely mammals, has established several foci in the western Palaearctic regions. …”
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Mice develop obesity and lose myocardial metabolic flexibility months after exertional heat stroke by Jamal M. Alzahrani, Ashley J. Smuder, Bryce J. Gambino, Cristina Delgado, Michael T. Rua, Ryan N. Montalvo, Finleigh P. Fitton, Deborah A. Morse, Thomas L. Clanton

“…These results demonstrate that a single exposure to severe exertional heat illness can induce long-lasting and unexpected health consequences in mammals and increased vulnerability to secondary metabolic stressors.…”
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The Leech Nervous System: A Valuable Model to Study the Microglia Involvement in Regenerative Processes by Françoise Le Marrec-Croq, Francesco Drago, Jacopo Vizioli, Pierre-Eric Sautière, Christophe Lefebvre

“…During pathologies in mammals, inflammatory processes implicate the resident microglia and the infiltration of blood cells including macrophages. …”
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Stable Long-Term Culture of Human Distal Airway Stem Cells for Transplantation by Yueqing Zhou, Yujia Wang, Dandan Li, Ting Zhang, Yu Ma, Wei Zuo

“…There is a population of p63+/Krt5+ distal airway stem cells (DASCs) quiescently located in the airway basal epithelium of mammals, responding to injury and airway epithelial regeneration. …”
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Species Differences in Paraoxonase Mediated Hydrolysis of Several Organophosphorus Insecticide Metabolites by Russell L. Carr, Mary Beth Dail, Howard W. Chambers, Janice E. Chambers

“…PON1 activity is present in most mammals and previous research established that PON1 activity differs depending on the species. …”
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Neuroinflammation as Fuel for Axonal Regeneration in the Injured Vertebrate Central Nervous System by Ilse Bollaerts, Jessie Van houcke, Lien Andries, Lies De Groef, Lieve Moons

“…Lastly, we shed light on the impact of aging processes on the regenerative capacity in the CNS of mammals and zebrafish. As aging not only affects the CNS, but also the immune system, the regeneration potential is expected to further decline in aged individuals, an element that should definitely be considered in the search for novel therapeutic strategies.…”
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Detection of chimeric alpha-defensin transcripts and peptides in mouse Paneth cells by Steven Timmermans, Steven Timmermans, Charlotte Wallaeys, Charlotte Wallaeys, Somara De Beul, Somara De Beul, Natalia Garcia-Gonzales, Natalia Garcia-Gonzales, Claude Libert, Claude Libert

“…IntroductionIn mammals, Paneth cells, located in the crypts of the small intestine, produceantimicrobial peptides that serve to keep the intestinal microbiome under control. a-Defensins are the primary antimicrobial peptides produced by these cells.MethodsWe used 148 publicly available bulk RNA-seq samples on purified PCs, proteomics on enriched purified PC proteins and Defa peptide activity assays to detect all Defa transcrips, including potential chimeric transcrips.ResultsWe identified 28 expressed Defa genes in mice, with up to 85% of Paneth cell RNA reads mapping to these genes. …”
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The long non-coding RNA Cerox1 is a post transcriptional regulator of mitochondrial complex I catalytic activity by Tamara M Sirey, Kenny Roberts, Wilfried Haerty, Oscar Bedoya-Reina, Sebastian Rogatti-Granados, Jennifer Y Tan, Nick Li, Lisa C Heather, Roderick N Carter, Sarah Cooper, Andrew J Finch, Jimi Wills, Nicholas M Morton, Ana Claudia Marques, Chris P Ponting

“…Cerox1 function is conserved across placental mammals: human and mouse orthologues effectively modulate complex I enzymatic activity in mouse and human cells, respectively. …”
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Zebrafish as a model for human epithelial pathology by Ahmed Abu-Siniyeh, Moayad Khataibeh, Walid Al-Zyoud, Majed Al Holi

“…Zebrafish possess significant cellular and functional homology with mammals, which facilitates the investigation of various diseases, including inflammatory bowel disease, nonalcoholic fatty liver disease, and polycystic kidney disease. …”
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Flora i fauna rezerwatu przyrody Jezioro Kiełpińskie i sąsiednich starorzeczy w strefie podmiejskiej Warszawy by Jerzy Romanowski, Paweł Boniecki, Anita Kaliszewicz, Marek Kloss, Izabella Olejniczka

“…A large number of protected species of plants and vertebrates were recorded in the area, including amphibians, birds, and mammals that are of particular importance to the European community, such as the fire-bellied toad, little bittern, western marsh harrier, beaver, and otter. …”
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Bats as an Important Source of Antimicrobial-Resistant Bacteria: A Systematic Review by Julio D. Soto-López, Manuel Diego-del Olmo, Pedro Fernández-Soto, Antonio Muro

“…<b>Background/Objectives</b>: Bats are the second-largest known order of mammals, accounting for about twenty percent of the species described to date. …”
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Collagen V Is a Potential Substrate for Clostridial Collagenase G in Pancreatic Islet Isolation by Hiroki Shima, Akiko Inagaki, Takehiro Imura, Youhei Yamagata, Kimiko Watanabe, Kazuhiko Igarashi, Masafumi Goto, Kazutaka Murayama

“…The enzymatic activity of collagenase G appears to be more important for pancreatic islet isolation in large mammals such as pigs and humans.…”
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Plate rod in humerus fracture in Caracara plancus: Challenges and outcomes of a case by J.R. Leitão, I.R. Rosado, T.T.P. Menezes, M.G. Lopes, E.G.L. Alves

“…Although commonly used in mammals, this technique has not yet been documented in avian medicine. …”
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Natural Catalytic Antibodies in Norm, Autoimmune, Viral, and Bacterial Diseases by Georgy A. Nevinsky, Valentina N. Buneva

“…Different mechanisms of Abz production can be proposed for healthy externally immunized and for autoimmune mammals during the development of pathology.…”
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