Acute Lymphoblastic Leukemia following Lenalidomide Maintenance for Multiple Myeloma: Two Cases with Unexpected Presentation and Good Prognostic Features by Abdullah M. Khan, Jameel Muzaffar, Hermant Murthy, John R. Wingard, Jan S. Moreb

“…A recent meta-analysis has provided additional evidence that lenalidomide maintenance is associated with a higher incidence of second primary malignancies, including both hematologic and solid malignancies. …”
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IL6 Induces mtDNA Leakage to Affect the Immune Escape of Endometrial Carcinoma via cGAS-STING by Xue Zeng, Xiaosong Li, Yundong Zhang, Chaoxia Cao, Qin Zhou

“…Endometrial carcinoma (EC) is a commonly diagnosed gynecological malignancy. Interleukin-6 (IL6) plays a critical role in modulating the progression of several types of tumors, including EC. …”
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Primary Pericardial Sarcoma with Right Atrial Invasion and Multiple Bilateral Pulmonary Metastases in a Patient with Hereditary Nonpolyposis Colorectal Cancer by Eugene Wong, Lawrence J. Oh, Kazi Nahar, Adrian Lee, Stephen Clarke

“…The most common pericardial malignancy is mesothelioma. Sarcomas are soft-tissue mesenchymal malignancies originating from various parts of the body but are extremely rare in this area. …”
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Diverse Presentations of Carcinoma Erysipelatoides from a Teaching Hospital in Australia by Hui Ting Chow, Kim Tran, Ewan K. A. Millar, Jodi Lynch, Dedee F. Murrell

“…This case series describes four patients seen at our institution with a diagnosis of inflammatory breast cancer; 3 patients had a history of previously treated breast malignancy. In these cases, the emergence of a new breast lesion evaded initial diagnosis due to incomplete initial physical examination, falsely reassuring imaging results, lack of recognition that a cellulitis picture can resemble metastatic carcinoma, and inconclusive initial biopsy sections. …”
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Rapidly Growing Chondroid Syringoma of the External Auditory Canal: Report of a Rare Case by Ioannis Vasileiadis, Stylianos Kapetanakis, Aristotelis Petousis, Euthimios Karakostas, Christos Simantirakis

“…In our case, the new information is that this benign tumor could present also as a rapidly growing lesion, arising the suspicion for malignancy.…”
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Juvenile Myelomonocytic Leukemia in a Child: A Case Report of Palliative Chemotherapy and Literature Review Applied to Limited Resources Centers by Natharina Yolanda, Stefanus Gunawan, Max F. J. Mantik, Anjo J. P. Veerman

“…Juvenile myelomonocytic leukemia (JMML) is a rare hematopoietic malignancy in children, with an incidence of 1.2 per million children per year. …”
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Massive Multinodular Head and Neck Recurrence of Parotid Gland Pleomorphic Adenoma: A Case Report by Pierre Philouze, Nicolas Sigaux, Anne Frédérique Manichon, Jean-Christian Pignat, Marc Poupart

“…The optimal initial management of parotid pleomorphic adenomas reduces the risk of recurrence and malignant transformation. Surgery of recurrence can be difficult in multinodular disseminated forms. …”
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Development of Thermoresponsive Composite Hydrogel Loaded with Indocyanine Green and Camptothecin for Photochemotherapy of Skin Cancer After Surgery by Yu-Hsiang Lee, Chieh-Lin Chung

“…Skin cancer is the world’s fifth most diagnosed malignancy and is increasingly occurring in young adults. …”
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Systemic Sclerosis and Multiple Cancers of the Female Genital Tract: Prolonged Survival following Current Treatment Strategies by Georgios Androutsopoulos, Georgios Adonakis, Athanasios Tsamandas, Andreas Andonopoulos, Georgios Decavalas

“…There is an overall increased risk of malignancy in patients with systemic sclerosis. However, multiple cancers of the female genital tract in patients with SSc are a very rare event. …”
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Gastric Linitis Plastica and Peritoneal Carcinomatosis as First Manifestations of Occult Breast Carcinoma: A Case Report and Literature Review by Mara Mantiero, Giovanni Faggioni, Alice Menichetti, Matteo Fassan, Valentina Guarneri, Pierfranco Conte

“…Breast cancer is the most frequent malignancy in women, and the metastatic spread to the stomach occurs in less than 10% of the cases. …”
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Primary Small Cell Carcinoma of the Vagina by Rafael Oliveira, Mayra Coelho Bócoli, João Carlos Saldanha, Eddie Fernando Candido Murta, Rosekeila Simões Nomelini

“…The primary small cell carcinoma of the vagina is rare, and it is a highly aggressive malignancy with no consensus regarding the treatment of this tumor. …”
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A Unique Case of Intraabdominal Polyorchidism: A Case Study by Javier Otero, Natalie Ben-Yakar, Biruk Alemayehu, Steven D. Kozusko, Frank Borao, Thomas S. Vates III

“…Orchiopexy should be performed to reduce the chances of torsion, malignancy, and infertility. Conclusion. Our case is important to the literature as it is the first known case of polyorchidism with 3 SNT on the right side, located intra-abdominally, and in a patient less than 1 year of age.…”
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An Unusual Case of Mammary Paget’s Disease Diagnosed Using Dynamic Contrast-Enhanced MRI by Eleonora Gaspari, Aurora Ricci, Valeria Liberto, Angela Lia Scarano, Maria Fornari, Giovanni Simonetti

“…At clinical examination, it is characterized by skin lesions of the nipple-areola complex, almost always a sign of malignancy. In fact, it is often associated with an underlying mammary ductal carcinoma in situ (DCIS) or invasive carcinoma. …”
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Urinary Bladder Adenocarcinoma Metastatic to the Abdominal Wall: Report of a Case with Cytohistologic Correlation by Vikas Nath, Mithra Baliga

“…Primary bladder adenocarcinoma is a rare malignancy arising within glandular metaplasia and is associated with cystitis cystica and cystitis glandularis. …”
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Relationship among Tobacco Habits, Human Papilloma Virus (HPV) Infection, p53 Polymorphism/Mutation, and the Risk of Oral Squamous Cell Carcinoma by Neha Gupta, Gargi Yumnam, Chetan Sharma, Avani Patel, Ripudaman Sharma, Sachin Dev, Mahesh Ghadage

“…Background: Oral squamous cell carcinoma (OSCC) is a multifactorial malignancy influenced by various genetic and environmental factors. …”
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Seroprevalence and Biomarkers Detection of Human Herpes Virus (HHV-8) in Patients with Kaposi Sarcoma by Abdulrazzaq Neamah Zghair, Sumayah Faruq Kasim, Nazar Sh. Mohammed, Anil K. Sharma

“… Kaposi's sarcoma (KS) represents the most prevalent malignancy among untreated HIV-positive individuals. …”
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Control of Cellular Differentiation Trajectories for Cancer Reversion by Jeong‐Ryeol Gong, Chun‐Kyung Lee, Hoon‐Min Kim, Juhee Kim, Jaeog Jeon, Sunmin Park, Kwang‐Hyun Cho

“…It is found that simultaneous knockdown of these master regulators can revert colorectal cancer cells into normal‐like enterocytes by synergistically inducing differentiation and suppressing malignancy, which is validated by in vitro and in vivo experiments.…”
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Bilateral Jugular Vein and Sigmoid Sinus Thrombosis Related to an Inherited Coagulopathy: An Unusual Presentation by Özge Altıntaş, Azize Esra Gürsoy, Gözde Baran, Elnur Mehdi, Talip Asil

“…Internal jugular vein thrombosis (IJVT) is a rare condition associated with malignancy, coagulopathy, and trauma. The optimal management of any IJVT must be individualized and depends on the condition of the patient. …”
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Ocular Hypertropia Mimicking Inferior Rectus Palsy as an Atypical Presentation of Parameningeal Rhabdomyosarcoma in a Child by Alhodaly H, Aldohayan N, Alhamazani M, Alanazy T, Bazuhair MS

“…Early and accurate diagnosis is crucial for the effective management of children with such aggressive malignancy.Keywords: rhabdomyosarcoma, parameningeal, hypertropia, trauma, case report…”
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Whole-Body 18FDG-PET in an Arthritis Paraneoplastic Syndrome Revealed an Underlying Hematological Neoplasm by Serge Cammilleri, Marie Caroline Guzian, Jean-Pierre Mattei, Olivier Mundler, Sandrine Guis

“…About 4% of patients with lymphoma or leukemia suffered from rheumatologic paraneoplastic symptoms like arthralgia and about 10% of the patients with rheumatologic or neurologic clinical symptoms develop a solid cancer or hematological neoplasm. 18FDG-PET is an interesting exam to identify an underlying malignancy when a paraneoplastic syndrome is suspected; it can detect the primitive lesion and/or the metastasis lesions. …”
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