Advances in small extracellular vesicles: roles in the tumor microenvironment and epithelial ovarian cancer diagnosis and treatment by Liang Peng, Yi Lai, Baodi Cao

“…In addition, sEVs show significant promise as biomarkers and therapeutic agents for the treatment and management of this malignancy. This review explores recent advancements in the understanding of sEVs within the TME and their potential applications in the diagnosis and treatment of EOC.…”
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Bilateral Asynchronous Renal Cell Carcinoma with Metastatic Involvement of the Tongue by Naseem Ghazali, Charlotte Davis, A. W. Barrett, John V. Tighe

“…Due to end-stage primary pulmonary malignancy, and poor function of the remaining kidney, immunotherapy was unsuitable. …”
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Clinicopathologic characteristics, therapeutic modalities and survival outcomes of plasmablastic lymphoma: A real-world study by Yan-Hua Zheng, Kun Xie, Hong-Yuan Shen, Zhuo Wan, Shan Gao, Wen-Rui Sun, Guang-Xun Gao, Li Liu, Juan Feng

“…Patients who suffered from previous malignancy had a significant survival disadvantage compared to those without previous cancer. …”
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The Suppression of Signal Transducer and Activator of Transcription-3 in A549 human Lung Carcinoma Cells Induced by Marine Sponge Callyspongia aerizusa by Hadisaputri YE, Nurhaniefah AA, Mutakin M, Hendriani R, Rezano A, Sopyan I, Yusnaini Y, Asikin Y, Abdulah R

“…Moreover, IL-6 and HIF-1α mRNA expression levels decreased during 24 hours, while VEGF mRNA had a slight decrease compared to untreated cells.Conclusion: In conclusion, the ergosteroids present in marine sponge C. aerizusa extract signified a remarkable reduction in malignancy, migration, and invasion capabilities in A549 lung carcinoma cells. …”
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Unforeseen Hodgkin Lymphoma Hidden behind Hypercalcemia by Moutaz Ghrewati, Balraj Singh, Parminder Kaur, Michael Maroules

“…As one of the leading causes of hypercalcemia, malignancy is an essential consideration when patients present with such symptomology. …”
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Tuberculous Lymphadenitis Mimicking Nodal Metastasis in Follicular Variant Papillary Thyroid Carcinoma by Marc Gregory Yu, Jenny Maureen Atun

“…Preoperative workup suggested a thyroid malignancy with nodal metastasis. He underwent total thyroidectomy with node dissection where histopathology confirmed follicular variant- (FV-) PTC. …”
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T Cell-Tumor Interaction Directs the Development of Immunotherapies in Head and Neck Cancer by A. E. Albers, L. Strauss, T. Liao, T. K. Hoffmann, A. M. Kaufmann

“…Immunosurveillance is exerted mostly by cytotoxic T-lymphocytes (CTLs) while specific immune suppression is associated with tumor malignancy and progression. In squamous cell carcinoma of the head and neck, the presence, activity, but also suppression of tumor-specific CTL have been demonstrated. …”
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Shikonin Induces Glioma Necroptosis, Stemness Decline, and Impedes (Immuno)Proteasome Activity by Xianyun Qin, Lu Zhang, Jilan Liu, Yan Lu, Fuyao Zhou, Feng Jin

“…Gliomas, the most prevalent primary intracranial tumors, exhibit notable features such as heightened malignancy, rapid recurrence, and elevated mortality rates. …”
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Novel Treatment of Small-Cell Neuroendocrine of the Vagina by Kathryn Kostamo, Mishka Peart, Nathalie McKenzie, Conisha Holloman, S. J. Carlan, Li Ge, John Maksem

“…Primary vaginal small-cell neuroendocrine carcinoma is an extremely rare and highly aggressive malignancy. Eighty-five percent of patients die within one year of diagnosis from metastatic disease despite multimodal therapy. …”
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Mesonephric-like adenocarcinoma of the uterine corpus with focal sarcomatous differentiation: A case report by Serika Kanao, Makoto Urano, Kazuhisa Fujita, Fumi Utsumi, Kazuhiro Sugihara, Kiyosumi Shibata

“…A diagnosis is made at an advanced stage in comparison with other histological types of uterine corpus cancer, and the prognosis is reportedly poor with high-level malignancy. In addition, there are few case reports of mesonephric-like adenocarcinoma of the uterine corpus with sarcoma. …”
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Severe Lactic Acidosis in a Patient with B-Cell Lymphoma: A Case Report and Review of the Literature by Farn Huei Chan, Daniel Carl, Laurel J. Lyckholm

“…The pathogenesis of malignancy-induced lactic acidosis is not well understood; however associated factors include increased glycolysis, increased lactate production by cancer cells, and decreased hepatic clearance of lactate. …”
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Synchronous Occurrence of Primary Breast Carcinoma and Primary Colon Adenocarcinoma by Gurkan Yetkin, Fevzi Celayir, Ismail Ethem Akgun, Ramazan Ucak

“…Mammography and ultrasonography were performed for the cause of these findings, and suspicious lesions of malignancy were seen in the left breast. Invasive ductal carcinoma was detected in core needle biopsy samples from lesions. …”
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A Rare Tumor of Nasal Cavity: Glomangiopericytoma by Aysegul Verim, Cigdem Kalaycik Ertugay, Cigdem Tepe Karaca, Pembegul Gunes, Shahrouz Sheidaei, Cagatay Oysu

“…Glomangiopericytoma is categorized as a borderline low malignancy tumor by WHO classification. Long-term follow-up with systemic examination is necessary due to high risk of recurrence.…”
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Chemotherapy for Metastatic Gastric Cancer by Sung Eun Kim, Moo In Park, Myung Hun Lee

“…Gastric cancer is the fourth most common malignancy in Korea and remains the fifth and seventh leading cause of cancer death in males and females, respectively. …”
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Upper endoscopic findings in patients attending the endoscopy unit of al-azhar assiut university hospital: 2019–2020 by Hamdy M. Moustafa, Ahmed Q. Mohamed, Safwat S. Sawy, Amel A. Moustafa

“…Upper endoscopy has effective diagnostic and therapeutic functions; it can be used in patients with signs or symptoms suggestive of upper gastrointestinal (GI) disease, surveillance for upper gastrointestinal tract (GIT) malignancy in high-risk population, and also stoppage of upper GIT bleeding. …”
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MALT Lymphoma of the Bladder: A Case Report and Review of the Literature by Prashant Vempati, Miriam A. Knoll, Mahfood Alqatari, James Strauchen, Adriana K. Malone, Richard L. Bakst

“…In conclusion, primary MALT lymphoma of the bladder represents a rare malignancy with excellent prognosis if detected at an early stage. …”
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Variant Guillain-Barré Syndrome in a Patient with Non-Hodgkin’s Lymphoma by R. H. Bishay, J. Paton, V. Abraham

“…A discussion regarding common and uncommon neuropathies in haematological malignancies is made, with a brief review of the anecdotal evidence supporting a paraneoplastic association with GBS or its variant forms in the setting of lymphoma.…”
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Case Study: Chronic Recurrent Multifocal Osteomyelitis in the Femoral Diaphysis of a Young Female by Jeffrey S. Quon, Anne K. Dzus, David A. Leswick

“…Although CRMO has a benign course and responds well to anti-inflammatory medications, it can have a very aggressive clinical and imaging presentation overlapping with infectious osteomyelitis and malignancy. Therefore, radiologists and clinicians need to be aware of its clinical and imaging presentation to avoid morbidity associated with more aggressive treatment. …”
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Severe Primary Raynaud’s Disease Treated with Rituximab by Mohammed Shabrawishi, Abdurahman Albeity, Hani Almoallim

“…There were no symptoms of underlying autoimmune disease or malignancy, and autoimmune, serology, and immunology test results were normal; a biopsy of her left little finger was negative for vasculitis. …”
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Focal Xanthogranulomatous Pyelonephritis with Pulmonary Lesions on the Background of Type Two Diabetes Mellitus by Ahmad Enshaei, Arash A. Boora, Diana Taheri, Zahra Changizi, Nahid Bahmani

“…Imaging studies revealed several pulmonary lesions and a large mass of the right kidney which was indistinguishable from renal malignancy. After surgical resection of the right kidney, the lesion is pathologically diagnosed to be a focal Xanthogranulomatous pyelonephritis. …”
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