Prognostic Factors and Nomogram for Malignant Brainstem Ependymoma: A Population‐Based Retrospective Surveillance, Epidemiology, and End Results Database Analysis by Xiaoyu Ji, Siyuan Yang, Dejing Cheng, Wenbo Zhao, Xuebo Sun, Fang Su

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Case report: A rare case of chondrosarcoma-like malignant giant cell tumor in adolescent rib: diagnostic challenges and treatment by Zhuolin Qin, Longqian Li, Tao Jing, Cheng Wang

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Was It an Adrenocortical Adenoma or an Adrenocortical Carcinoma? Limitation of the Weiss Scoring System in Determining the Malignant Potential of Adrenocortical Tumor: Report on Two Cases by Cheuk-Lik Wong, Chun-Kit Fok, Yuk-Kit Chan, Vicki Ho-Kee Tam, Lai-Ming Fung

“…Adrenocortical carcinoma (ACC) is a rare endocrine malignancy. An accurate diagnosis of ACC is of paramount importance as it greatly impacts the management and prognosis of a patient. …”
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The Prophylactic Use of Lipid Emulsion Therapy in the Excision of Invasive Malignant Melanoma under Local Anaesthetic in a Morbidly Obese Patient by K. S. Sharma, P. Lim, T. M. Brotherston, P. Smith

“…We present the first reported case of the prophylactic use of lipid emulsion therapy in the removal of an extensive, circumferential malignant melanoma in a morbidly obese patient, under local anaesthetic. …”
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MELK prevents radiofrequency ablation-induced immunogenic cell death and antitumor immune response by stabilizing FABP5 in hepatocellular malignancies by Bu-Fu Tang, Wang-Ting Xu, Shi-Ji Fang, Jin-Yu Zhu, Rong-Fang Qiu, Lin Shen, Yang Yang, Qiao-You Weng, Ya-Jie Wang, Jia-Yi Ding, Xiao-Jie Zhang, Wei-Qian Chen, Li-Yun Zheng, Jing-Jing Song, Biao Chen, Zhong-Wei Zhao, Min-Jiang Chen, Jian-Song Ji

“…Conclusion MELK is a therapeutic target by regulating RFA efficacy in HCC, and targeting MELK via RGD-LNPs provides new insight into improving RFA efficacy in HCC clinical treatment and combating the malignant progression of liver cancer.…”
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Dual-positive gastric cancer: an extremely malignant subtype of gastric cancer with high serum alpha-fetoprotein and carcinoembryonic antigen concentrations by Weixun Xie, Chengyu Hu, Hongming Liu, Zelai Wu, Bixian Luo, Xiaoying Wu, Xiaoying Wu, Chuanlei Tuo, Ziyin Deng, Han Liang, Yong Liu, Weihua Gong, Weihua Gong

“…BackgroundAlpha-fetoprotein-producing gastric cancer (AFPGC) is a highly malignant subtype of gastric cancer, but solely alpha-fetoprotein may fail to accurately predict the prognosis. …”
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FKBP4 Accelerates Malignant Progression of Non-Small-Cell Lung Cancer by Activating the Akt/mTOR Signaling Pathway by Wen Meng, Jingfei Meng, Hong Jiang, Xing Feng, Dongshan Wei, Qingsong Ding

“…FKBP4 serves as an oncogene to promote malignant processes in NSCLC, and it has the potential to be used as a biological marker and therapeutic target for NSCLC.…”
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Diagnostic Value of Software-Based Image Fusion of Computed Tomography and F18-FDG PET Scans in Patients with Malignant Lymphoma by B. Henninger, D. Putzer, D. Kendler, C. Uprimny, I. Virgolini, E. Gunsilius, R. Bale

“…Sensitivity and specificity for detecting malignant lymphoma were 90% and 76% for CT and 94% and 91% for PET, respectively. …”
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Simultaneous presentation of malignant acanthosis nigricans and palmar fasciitis with polyarthritis syndrome in a patient of ovarian neoplasm: A rare manifestation by Jayati Dave, Sunanda Mahajan, Ankita Maheshwari, Abhishek Gupta

Subjects: “…malignant acanthosis nigricans…”
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Cyclooxygenase 2 (COX2) and Peroxisome Proliferator-Activated Receptor Gamma (PPARG) Are Stage-Dependent Prognostic Markers of Malignant Melanoma by Stefanie Meyer, Thomas Vogt, Michael Landthaler, Anna Berand, Albrecht Reichle, Frauke Bataille, Andreas H. Marx, Anne Menz, Arndt Hartmann, Leoni A. Kunz-Schughart, Peter J. Wild

“…Using tissue microarrays (TMAs) we studied COX2/PPARG immunoreactivity in a broad spectrum of tumors focussing on clinicopathological correlations and the outcome of patients with malignant melanoma (MM). TMA-1 contained normal and tumor tissues (n=3448) from 47 organs including skin neoplasms (n=323); TMA-2 88 primary MM, 101 metastases, and 161 benign nevi. …”
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Age-related features of some plasminogen activation system components content and activity in the blood of benign and malignant uterine body tumors by I. V. Kaplieva, G. V. Zhukova, V. R. Zakharchenko, E. M. Frantsiyants, E. V. Verenikina, Yu. A. Pogorelova, P. S. Kachesova, Yu. Yu. Kozel, N. A. Maximova, M. G. Ilchenko, E. I. Agarkova, A. S. Egorova

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Thyroid Nodules Located in the Lower Pole Have a Higher Risk of Malignancy than Located in the Isthmus: A Single-Center Experience by Gulhan Duman, Baris Sariakcali

“…Unlike the other localization studies, we found a higher risk of malignancy in the lower and similarly upper thyroid poles. …”
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Colorectal Malignancy in a Prospective Irish Inflammatory Bowel Disease Population 15 Years Since Diagnosis: Comparison with the EC-IBD Cohort by Mary Shuhaibar, Colm O’Morain

“…Patients who developed malignancies were logged electronically with verification of the site and histology. …”
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STAT5B::RARα-positive acute promyelocytic leukemia: Role of next generation sequencing in detection of a rare malignancy by Indranil Dey, Sushant Vinarkar, Mayur Parihar, Deepak Kumar Mishra

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Early and high-volume administration of sodium bicarbonate in sepsis-associated acute kidney injury in patients with malignancies, during continuous renal replacement therapy by Lamei Ouyang, Yin Pan, Ya-Fei Wu, Qiang Tang, Dao-Feng Wang, Ning Lou

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The prognostic value of circulating tumor DNA in malignant melanoma patients treated with immune checkpoint inhibitors: a systematic review and meta-analysis by Lei Liu, Shufu Hou, Aiping Zhu, Bing Yan, Linchuan Li, Dandan Song

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The effect of culture media and seeding densities on the human malignant testicular germ cell line (NT2/D1) growth pattern by Rawabi S. Altuwayjiri, Ibtesam S. Almami

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Role of Serum and Ultrasonometric Markers in the Early Diagnosis of Malignant Transformation of Periductal Liver Fibrosis in Patients with <i>Opisthorchis Felineus</i> Infection by A. Е. Kovshirina, O. S. Fedorova, Yu. V. Kovshirina, V. A. Petrov

“…Аim: to study the role of serum and ultrasonometric markers in the early diagnosis of malignant transformation of periductal fibrosis of the liver during the formation of cholangiocarcinoma against the background of chronic invasion of Opisthorchis felineus, in the population of endemic regions.Methods. …”
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Ominous Occurrence of Spinal Intradural Primary Malignant Peripheral Nerve Sheath Tumor Four Decades following Radiation Therapy for Testicular Seminoma by Osmond C. Wu, Berje H. Shammassian, Arunit J. S. Chugh, Aparna Harbhajanka, Manish K. Kasliwal

“…Primary intradural malignant peripheral nerve sheath tumor (MPNST) is an extremely rare diagnosis and is associated with an extremely poor prognosis. …”
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The added value of shear wave elastography when combined to conventional ultrasonography and fine-needle aspiration cytology in detection of malignant thyroid nodule by Ahmed Adel Abdallah, Maha Zaki Mahmoud, Mohamed Salah Hassouna, Khaled Elkaffas, Ahmad Mohamed Eltelety, Sameh M. Zamzam

“…Although the minority of thyroid nodules is malignant, invasive diagnostic procedures are often necessary. …”
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