High Prevalence of Human Papillomavirus in Colorectal Cancer in Hispanics: A Case-Control Study by Raul D. Bernabe-Dones, Maria Gonzalez-Pons, Alejandro Villar-Prados, Mercedes Lacourt-Ventura, Heriberto Rodríguez-Arroyo, Sharon Fonseca-Williams, Francisco E. Velazquez, Yaritza Diaz-Algorri, Sofia M. Lopez-Diaz, Nayra Rodríguez, Yasuhiro Yamamura, Marcia Cruz-Correa

“…Based on the high incidence of HPV-associated malignancies among Puerto Rican Hispanics, this study aimed to assess the prevalence of HPV infection and viral integration in colorectal tissues in order to evaluate its putative role in colorectal cancer (CRC). …”
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Identification of Aberrantly Expressed miRNAs in Gastric Cancer by Dan Liu, Xiaowei Hu, Hongfeng Zhou, Guangyue Shi, Jin Wu

“…Here, we report a miRNA profile of gastric cancer and provide new perspective to understand this malignant disease. This novel information suggests the potential roles of these miRNAs in the diagnosis, prognosis biomarkers, or therapy targets of gastric cancer.…”
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Insights into expression and localization of HPV16 LCR-associated transcription factors and association with LCR activity in HNSCC by Nikita Aggarwal, Divya Janjua, Apoorva Chaudhary, Udit Joshi, Tanya Tripathi, Chetkar Chandra Keshavam, Joni Yadav, Arun Chhokar, Alok Chandra Bharti

“…Human papillomavirus (HPV)-positive head and neck squamous cell carcinoma (HNSCC) encompasses a heterogeneous group of malignancies characterized by diverse clinical manifestations. …”
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Myeloid-derived suppressor cells exhibit distinct characteristics in bone marrow and blood of individuals with diffuse large B-cell lymphoma by Paris Efstratiou, Athina Damianaki, Aglaia Kavidopoulou, Polymnia Ioannidou, Effrosyni Markaki, Ioannis Moysis Skianis, Electra Tsagliotis, Vasilia Kaliafentaki, Angelos Mattheakakis, Maria Ximeri, Eleftherios Manouras, Matthieu Lavigne, Panayotis Verginis, Panayotis Verginis, Panayotis Verginis, Christina Kalpadakis

“…Antitumor immune surveillance is the key feature of tumour progression and response to treatment in various malignancies, such as lymphomas. Myeloid derived suppressor cells (MDSCs) are bone marrow (BM)-derived cells with potent suppressive properties, implicated in T cell inhibition and tumour dissemination. …”
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The Neuro-Inflammatory-Vascular Circuit: Evidence for a Sex-Dependent Interrelation? by Catherine Gebhard, Catherine Gebhard, Susan Bengs, Susan Bengs, Achi Haider, Achi Haider, Michael Fiechter, Michael Fiechter, Michael Fiechter

“…This newly suggested sex-dependent brain-heart interrelation was further supported by the discovery that bone marrow activity, a surrogate parameter of inflammation, represents a potential bridging link between amygdalar activity and cardiovascular pathology by fueling inflammatory processes that promote atherosclerotic disease. Such malignant cascade of events might account, at least in part, for the excess female mortality seen in women with coronary artery disease and calls for sex-specific research toward pharmacologic or behavioral modulators to improve cardiovascular outcomes, particularly in women. …”
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International Consensus Diagnostic Criteria for Autoimmune Pancreatitis and Its Japanese Amendment Have Improved Diagnostic Ability over Existing Criteria by Masahiro Maruyama, Takayuki Watanabe, Keita Kanai, Takaya Oguchi, Takashi Muraki, Hideaki Hamano, Norikazu Arakura, Shigeyuki Kawa

“…We compared the diagnostic abilities of the ICDC and JPS 2011 with those of the Japanese diagnostic criteria 2006 (JPS 2006), Korean diagnostic criteria (Korean), Asian diagnostic criteria (Asian), and HISORt diagnostic criteria in 110 patients with AIP and 31 patients with malignant pancreatic cancer. Results. The ICDC achieved the highest diagnostic ability in terms of accuracy (95.0%), followed by JPS 2011 (92.9%), Korean (92.2%), HISORt (88.7%), Asian (87.2%), and JPS 2006 (85.1%). …”
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Primary Diffuse Large B-Cell Lymphoma of the Liver in a Patient with Sjogren Syndrome by Vadim Gorodetskiy, Wolfram Klapper, Natalya Probatova, Vladimir Vasilyev

“…Sjögren’s syndrome (SS) has the highest incidence of malignant lymphoproliferative disorders transformation among autoimmune diseases. …”
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Validity and Advantages of Three-Dimensional High-Frequency Ultrasound in Dermatological Evaluation by Misaki Kinoshita-Ise, Taiichiro Ida, Tatsuro Iwasaki, Hideaki Iwazaki, Kazuyuki Yokota, Hoshito Taguchi, Manabu Ohyama

“…<b>Results:</b> Three-dimensional images were successfully obtained from skin tumors, including basal cell carcinoma, subungual squamous cell carcinoma, Bowen’s disease, and malignant melanoma, as well as inflammatory hair loss diseases including alopecia areata in different disease phases and lichen planopilaris. …”
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Intracranial ewings sarccoma mimicking middle 1/3rd parasagittal meningioma by Sharad Pandey, Pankaj Kumar, Purnima Paliwal, Achal Saxena, Sumit Deshpande, N. Monica

“…Abstract Background Ewing sarcoma is a malignant tumor arising in bone and soft tissue in children and young adults. …”
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Mitigation of doxorubicin-induced liver toxicity in mice breast cancer model by green tea and Moringa oleifera combination: Targeting apoptosis, inflammation, and oxidative stress by Abdulrahman H. Laftah, Nawfal Alhelfi, Sadeq K. Al Salait, Ammar B. Altemimi, Mohammad Reza Tabandeh, Efstathia Tsakali, Jan F.M. Van Impe, Ahmed A. Abd El-Maksoud, Tarek Gamal Abedelmaksoud

“…This study evaluated the effect of green tea and Moringa oleifera extracts (at 1 % and 2 % concentration) on DOX-treated breast cancer mice. 36 Balb/C female mice with breast cancer were split into healthy mice, 4 T1 cell cancer-induced, and Doxorubicin-induced malignancies. Assessments included weight, tumor size, liver enzymes, antioxidant enzymes, oxidative stress markers, pro-inflammatory cytokines, gene expressions for apoptosis and inflammation (BAX, BCL2, NLRP3, NFKB), and liver tissues were histopathologically examined. …”
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Early Detection of Oncological Diseases of the Digestive System (Guidelines of the Russian Gastroenterological Association and the Russian Association of Oncologists for Primary Ca... by V. T. Ivashkin, I. V. Mayev, A. D. Kaprin, M. Yu. Agapov, D. N. Andreev, A. S. Vodoleev, M. Yu. Zharkova, M. P. Korolev, Yu. A. Kucheryavyi, T. L. Lapina, M. V. Mayevskaya, A. V. Okhlobystin, Ch. S. Pavlov, A. V. Paraskevova, S. S. Pirogov, E. A. Poluektova, D. E. Rumyantseva, A. S. Trukhmanov, P. V. Tsarkov, A. A. Sheptulin, O. S. Shifrin

“…The present guidelines intended for primary care physicians are aimed at facilitating early diagnosis of malignant tumours of the digestive system, which can significantly improve the immediate and long-term results of their treatment.General provisions. …”
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A new NCL-targeting aptamer-drug conjugate as a promising therapy against esophageal cancer by Xue Zheng, Ying Wang, Huaiyu Duan, Junqi Hou, Shiming He

“…Abstract Esophageal cancer (EC) is one of the most common highly malignant tumors of the digestive system, with a poor prognosis under current treatment regimens. …”
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Cytochrome P450 Metabolism of Betel Quid-Derived Compounds: Implications for the Development of Prevention Strategies for Oral and Pharyngeal Cancers by Che-Yi Lin, Tien-Szu Pan, Chun-Chan Ting, Shih-Shin Liang, Shu-Hung Huang, Hsiu-Yueh Liu, Edward Cheng-Chuan Ko, Chung-Wei Wu, Jen-Yang Tang, Ping-Ho Chen

“…Betel quid (BQ) products, with or without tobacco, have been classified by the International Agency for Research on Cancer (IARC) as group I human carcinogens that are associated with an elevated risk of oral potentially malignant disorders (OPMDs) and cancers of the oral cavity and pharynx. …”
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Diagnostic challenges in the diagnosis and treatment of ovarian cancer in Lynch syndrome by Agnieszka Protasiuk, Agata Żak, Rafał Sierzpowski, Patrycja Tymoszuk, Bartosz Kasperek, Katarzyna Augustowska

“… Introduction and purpose Lynch syndrome (LS), also known as hereditary nonpolyposis colorectal cancer (HNPCC), is an autosomal dominant genetic disorder characterized by a significantly increased risk of developing various malignancies, including ovarian cancer. This study aims to analyse the risk of ovarian cancer development in patients with Lynch syndrome and to compare the diagnostic and therapeutic approaches for this neoplasm in the context of sporadic cases. …”
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Using a Herd Profile to Determine Age-Specific Prevalence of Bovine Leukemia Virus in Michigan Dairy Herds by Ronald J. Erskine, Paul C. Bartlett, Todd M. Byrem, Chelsea L. Render, Catherine Febvay, Jessica T. Houseman

“…Enzootic bovine leukosis is a contagious disease of cattle caused by the retrovirus, bovine leukemia virus (BLV) and is the most common cause of malignant neoplasm in cattle. In order to facilitate surveillance of this disease in dairy herds, we developed a method to combine ELISA of milk collected during routine production testing with a prescribed sampling of cows that is independent of the proportion of cows within each lactation. …”
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Epithelial–Mesenchymal Transition Suppression by ML210 Enhances Gemcitabine Anti-Tumor Effects on PDAC Cells by Keisuke Takemura, Kyohei Ikeda, Hayato Miyake, Yoshio Sogame, Hiroaki Yasuda, Nobuhiro Okada, Kazumi Iwata, Junichi Sakagami, Kanji Yamaguchi, Yoshito Itoh, Atsushi Umemura

“…Since EMT is a major malignant phenotype of PDAC, our findings may lead to the advancement of PDAC therapy, especially in the prevention of postoperative recurrence.…”
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Maltoma of Thyroid: A Rare Thyroid Tumour by Navisha Latheef, Vijendra Shenoy, M. Panduranga Kamath, Mahesh Chandra Hegde, A. Raghavendra Rao

“…Primary thyroid lymphomas constitute up to 5% of all thyroid malignancies and can be divided into non-Hodgkin’s lymphomas (NHLs) of B- and T-cell types, as well as Hodgkin’s lymphomas. …”
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Classification of Melanoma and Nevus in Digital Images for Diagnosis of Skin Cancer by Muhammad Qasim Khan, Ayyaz Hussain, Saeed Ur Rehman, Umair Khan, Muazzam Maqsood, Kashif Mehmood, Muazzam A. Khan

“…The mortality rate because of this disease is higher than all other skin-related consolidated malignancies. The number of cases is growing among young people, but if it is diagnosed at an earlier stage, then the survival rates become very high. …”
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Primary large B-cell lymphoma of the central nervous system misdiagnosed as autoimmune encephalitis: a case report by Aihui Ren, Guanwen Zeng, Riling Chen, Zhixing Cao, Wenyan Zhuo, Yubin Liang, Yubin Liang

“…Primary central nervous system lymphomas (PCNSL) are rare, constituting 2 - 3% of intracranial malignancies. A 49-year-old male presented with a 20-day history of dizziness and a 15-day history of right-sided weakness. …”
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Global Research Landscape and Intellectual Structure of Boron Neutron Capture Therapy Research: A Review Based on Scientometric Tools by Elmira Janavi, Maryamm Emami, Manoj Kumar Verma

“…Boron Neutron Capture Therapy (BNCT) is a non-invasive therapeutic technique for treating invasive malignant tumors. A tremendous amount of research is published in this area every year, and it needs to be analyzed and evaluated to measure the growth and trends of the research. …”
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