Out-of- hospital mortality in the municipality of Cienfuegos, 2016 by Orlando Morera Álvarez, Daylin Madruga Jiménez, Liliana Caridad Romero Castro

“…<br /><strong>Results</strong>: 86.4 % of deaths occurred at home, with a male predominance (50.4 %), and of people 65 years of age and older. Malignant tumors were the leading cause of death (rate of 79.1 x 10,000 inhabitants), followed by heart disease.…”
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Advances in adjuvant therapy for operable N2 non-small cell lung cancer: a narrative review by Lei Liu, Yilong Mao, Leilei Guo, Chencong Li, Yiqian Wang

“…Non-small cell lung cancer (NSCLC) is still the disease with the highest incidence rate among malignant tumors, in which NSCLC under N2 stage has obvious survival differences among different patients due to its high heterogeneity. …”
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Evaluation of Geomorphological Capabilities in Kermanshah Province in Locating Sensitive and Important Centers with Passive Defense Approach by zahra heidari, asadolah heqazi, shahram rostaei, siros fakhri

“…Given Iran's ongoing role in the Middle East and the constant threat of external threats, it is imperative that I take action on the critical and important steps of my country Of the measures that can prevent the occurrence of malignancies , Kermanshah region due to its geographical location and proximity to Iraq as well as its complex morphology include high mountainous lands, relatively wide valleys and plains, geological structural diversity and With the immediate approach, Identify these natural features It creates the right places With passive defense approach To establish these centers. …”
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Renal Cell Carcinoma in Fistulizing Crohn’s Disease Patient Who Received Anti-TNF α Therapy by Abdullah Mohammed Albishi, Rafaat Chakik, Mohammed Bazeed

“…These chronic inflammatory diseases are associated with an increased risk for both intestinal and different types of extra-intestinal malignancies. In this case report, we describe the condition of a 29-year-old Saudi male diagnosed with fistulizing ileal Crohn’s disease 7 years ago. …”
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The Effect of Economic Factors on Coffee Consumption in Rukungiri District, South-Western Uganda by moses Agaba

“…Rukungiri District production and marketing department has pursued campaigns to educate the public about the health benefits of coffee, including its high antioxidant content, potential to prevent certain malignancies, and potential to lower type 2 diabetes risk. …”
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Cilostazol protective effect on nedaplatin-induced genotoxicity in cultured human lymphocytes by Karem H. Alzoubi, Abeer M. Rababa’h, Omar F. Khabour, Fian Nuseir

“…Background: Nedaplatin has demonstrated remarkable efficacy in combating various malignancies. However, the administration of nedaplatin has been associated with the induction of DNA damage within normal cells. …”
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mRNA vaccines in the context of cancer treatment: from concept to application by Qiang Fu, Xiaoming Zhao, Jinxia Hu, Yang Jiao, Yunfei Yan, Xuchen Pan, Xin Wang, Fei Jiao

“…Among the diverse immunotherapy strategies, mRNA vaccines have ushered in a new era for the therapeutic management of malignant diseases, primarily due to their impressive impact on the COVID-19 pandemic. …”
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Protracted Clonal Trajectory of a JAK2 V617F-Positive Myeloproliferative Neoplasm Developing during Long-Term Remission from Acute Myeloid Leukemia by Stephen E. Langabeer, Karl Haslam, Maria Anne Smyth, John Quinn, Philip T. Murphy

“…Alternatively, both malignancies possibly evolved from a common precursor defined by a predisposition mutation with divergent evolution into MPN through acquisition of the JAK2 V617F and AML through acquisition of different mutations. …”
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Sepsis-Induced Takotsubo Cardiomyopathy Leading to Torsades de Pointes by Nirav Patel, Abhishek Shenoy, George Dous, Haroon Kamran, Nabil El-Sherif

“…Though traditionally elicited by physical and emotional triggers leading to transient left ventricular dysfunction, our case suggests that it may also be triggered by a urinary tract infection and lead to severe QT prolongation and a malignant ventricular arrhythmia in TdP.…”
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Characterization of an Implicitly Resistively-Loaded Monopole Antenna in Lossy Liquid Media by Colleen J. Fox, Paul M. Meaney, Fridon Shubitidze, Lincoln Potwin, Keith D. Paulsen

“…Microwave tomographic imaging of the breast for cancer detection is a topic of considerable interest because of the potential to exploit the apparent high-dielectric property contrast between normal and malignant tissue. An important component in the realization of an imaging system is the antenna array to be used for signal transmission/detection. …”
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Cyclin E1/CDK2 activation defines a key vulnerability to WEE1 kinase inhibition in gynecological cancers by Daehwan Kim, Heekyung Chung, Wen Liu, Kangjin Jeong, Tugba Y. Ozmen, Furkan Ozmen, Matthew J. Rames, Sangyub Kim, Xiao Guo, Nathan Jameson, Petrus R. de Jong, Steven Yea, Laurie Harford, Jiali Li, Cara A. Mathews, Deborah B. Doroshow, Vincent J. Charles, Doris Kim, Kimberlee Fischer, Ahmed A. Samatar, Adrian Jubb, Kevin D. Bunker, Kimberly Blackwell, Fiona Simpkins, Funda Meric-Bernstam, Gordon B. Mills, Olivier Harismendy, Jianhui Ma, Mark R. Lackner

“…Abstract Upregulation of Cyclin E1 and subsequent activation of CDK2 accelerates cell cycle progression from G1 to S phase and is a common oncogenic driver in gynecological malignancies. WEE1 kinase counteracts the effects of Cyclin E1/CDK2 activation by regulating multiple cell cycle checkpoints. …”
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Identification of Associations with Dermatologic Diseases through a Focused GWAS of the UK Biobank by Jason C. Klein, Ruchika Mahapatra, Gary C. Hon, Richard C. Wang

“…We perform a focused analysis of the UK Biobank for 13 dermatologic conditions, including malignant melanoma, melanoma in situ, squamous cell carcinoma, basal cell carcinoma, actinic keratosis, seborrheic keratosis, psoriasis, lichen planus, systemic lupus erythematosus, hyperhidrosis, pilonidal cyst, sebaceous cyst, and lipoma. …”
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Network Pharmacology Reveals Polyphyllin II as One Hit of Nano Chinese Medicine Monomers against Nasopharyngeal Carcinoma by Meng-Zhe Yang, Bei-Bei Zhang, Jian-Chun Huang, Xian-Yu Bai, Zhen-Qiang Liang, Xiang Yi, Ning Xu, Yuan-Jiao Huang, Ai-Jun Jiao

“…Nasopharyngeal carcinoma (NPC) is a malignant tumor in southern China, and nano Traditional Chinese Medicine (TCM) represents great potential to cancer therapy. …”
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Inefficacy of treatment modalities of oral lichen planus: Evidence-based results by Namrata Sengupta, Sachin C. Sarode, Gargi S. Sarode, Rahul Anand, Dharmarajan Gopalakrishnan

“…Long-term untreated symptoms of OLP increases the malignant transformation rate. Hence, many studies have investigated and reported the efficacy of various therapeutic agents in managing the clinical symptoms of OLP. …”
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Delineating Molecular Mechanisms of Squamous Tissue Homeostasis and Neoplasia: Focus on p63 by Kathryn E. King, Linan Ha, Tura Camilli, Wendy C. Weinberg

“…In vitro keratinocytes and murine transgenic and transplantation models have been invaluable in elucidating the contribution of altered p63 levels to cancer development, and studies have identified the roles for ΔNp63 isoforms in keratinocyte survival and malignant progression, likely due in part to their transcriptional regulatory function. …”
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Chronic Lymphocytic Leukemia and Myelofibrosis by Fares Darawshy, Arieh Ben-Yehuda, Karine Atlan, Deborah Rund

“…Chronic lymphocytic lymphoma (CLL) can be associated with several malignancies, but rarely with myelofibrosis. Only isolated case reports in the literature described the association between CLL and primary myelofibrosis (PMF) in the same patient. …”
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The Influence of Monoamine Oxidase Variants on the Risk of Betel Quid-Associated Oral and Pharyngeal Cancer by Ping-Ho Chen, Bin Huang, Tien-Yu Shieh, Yan-Hsiung Wang, Yuk-Kwan Chen, Ju-Hui Wu, Jhen-Hao Huang, Chun-Chia Chen, Ka-Wo Lee

“…Betel quid (BQ) and areca nut (AN) (major BQ ingredient) are group I human carcinogens illustrated by International Agency for Research on Cancer and are closely associated with an elevated risk of oral potentially malignant disorders (OPMDs) and cancers of the oral cavity and pharynx. …”
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Bone‐Targeted Fluoropeptide Nanoparticle Inhibits NF‐κB Signaling to Treat Osteosarcoma and Tumor‐Induced Bone Destruction by Lin Li, Guangyu Rong, Xin Gao, Yiyun Cheng, Zhengwang Sun, Xiaopan Cai, Jianru Xiao

“…Abstract Osteosarcoma is a malignant bone cancer usually characterized by symptoms of bone loss due to pathologically enhanced osteoclast activity. …”
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Targeting Bone Metabolism in Patients with Advanced Prostate Cancer: Current Options and Controversies by Tilman Todenhöfer, Arnulf Stenzl, Lorenz C. Hofbauer, Tilman D. Rachner

“…Novel agents targeting the Wnt inhibitors dickkopf-1 and sclerostin are currently under investigation for the treatment of osteoporosis and malignant bone disease. New antineoplastic drugs such as abiraterone, enzalutamide, and Radium-223 are capable of further delaying SREs in patients with advanced PC. …”
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Bacteria as Precision Tools for Cancer Therapy by Carmen Michán, José Prados, Juan‐Luis Ramos

“…These bacterial ‘killer’ genes were then assayed for their potential to target and control malignant cells in human cancers. The identification of the bacteriomes in different human organs and tissues, coupled with the observation that bacteria tend to accumulate near tumours, has opened new avenues for anti‐cancer strategies. …”
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