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3561
Targeting glycolysis: exploring a new frontier in glioblastoma therapy
Published 2025-01-01“…Glioblastoma(GBM) is a highly malignant primary central nervous system tumor that poses a significant threat to patient survival due to its treatment resistance and rapid recurrence.Current treatment options, including maximal safe surgical resection, radiotherapy, and temozolomide (TMZ) chemotherapy, have limited efficacy.In recent years, the role of glycolytic metabolic reprogramming in GBM has garnered increasing attention. …”
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3562
Sudden Cardiac Death: The Most Feared but Potentially Preventable Presentation of Wolff-Parkinson-White Syndrome
Published 2021-01-01“…The prognosis is usually good, but there is a lifetime risk of malignant arrhythmias and sudden cardiac death. Case Summary. …”
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3563
Delirium in geriatric population referred to a geriatric clinic in a rural medical college: A retrospective study
Published 2024-12-01“…Other causes included malignancies, septicemia, and lung diseases. Hyponatremia was notably prevalent, especially among males (75%) in the 70–79 years’ age group. …”
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3564
Exercise as an Adjuvant Therapy for Hematopoietic Stem Cell Mobilization
Published 2016-01-01“…Hematopoietic stem cell transplant (HSCT) using mobilized peripheral blood hematopoietic stem cells (HSPCs) is the only curative strategy for many patients suffering from hematological malignancies. HSPC collection protocols rely on pharmacological agents to mobilize HSPCs to peripheral blood. …”
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3565
Heberferón®’s economic feasibility in patients with high-grade brain tumors without therapeutic options
Published 2024-07-01“…<br /><strong>Conclusions:</strong> the economic feasibility of using Heberferón® was evident, when comparing it with other products to treat patients with highly malignant brain tumors without therapeutic options.…”
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3566
Broadening horizons: research on ferroptosis in lung cancer and its potential therapeutic targets
Published 2025-01-01“…Lung cancer is one of the leading malignancies worldwide in terms of incidence and mortality, and its complex biological mechanisms and resistance make treatment challenging. …”
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3567
Convergence of nanotechnology and artificial intelligence in the fight against liver cancer: a comprehensive review
Published 2025-01-01“…Abstract Liver cancer is one of the most challenging malignancies, often associated with poor prognosis and limited treatment options. …”
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3568
RPL39 Was Associated With Sex Differences in Pulmonary Arterial Hypertension
Published 2025-01-01“…Pulmonary arterial hypertension (PAH) is a malignant cardiovascular disease with a complex etiology, in which several types of cells play important roles. …”
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3569
Non-useful Papanicolaou smears. Analysis of their causes in the first semester 2005 in Cienfuegos city, Cuba
Published 2008-12-01“…It is the first cause of mortality among malignant neoplasias in the female reproductive apparatus. …”
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3570
Viral mimicry evasion: a new role for oncogenic KRAS mutations
Published 2025-02-01“…This response has been shown to have strong cancer therapeutic potential, including by enhancing the effectiveness of immune checkpoint inhibition (ICI) therapies, and may represent a tumor suppression mechanism that needs to be overcome for malignant transformation to proceed. In a recent study, Zhou and colleagues identify KRAS, a frequently mutated oncogene, as a negative regulator of dsRNA and viral mimicry in an ICI‐resistant colorectal cancer model. …”
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3571
AIDS-Related Non-Hodgkin's Lymphoma in the Era of Highly Active Antiretroviral Therapy
Published 2012-01-01“…In economically developed countries, AIDS-related lymphoma (ARL) accounts for a large proportion of malignances in HIV-infected individuals. Since the introduction of highly active anti-retroviral therapy (HAART) in 1996, epidemiology and prognosis of ARL have changed. …”
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3572
Application of an improved LightGBM hybrid integration model combining gradient harmonization and Jacobian regularization for breast cancer diagnosis
Published 2025-01-01“…Abstract Cancer, as a shocking disease, is one of the most common malignant tumors among women, posing a huge threat to the physical health and safety of women worldwide. …”
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3573
Breast Cancer. A Characterization in the Decade from 1996-2005.
Published 2007-12-01“…<p><strong>Background:</strong> Breast Cancer constitutes a health problem in Cuba due to it is the first cause and localization of death for malignant tumors in females. This situation has been considered by our health Minister as a number one priority of investigation. …”
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3574
Advanced Alveolar Soft Part Sarcoma Treated with Pazopanib over Three Years
Published 2017-01-01“…Alveolar soft part sarcoma (ASPS) is a rare malignant tumor that generally occurs in adolescents and young adults. …”
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3575
Knockdown MTDH Inhibits Glioma Proliferation and Migration and Promotes Apoptosis by Downregulating MYBL2
Published 2022-01-01“…Glioma is a malignant tumor that often occurs in the adult central nervous system. …”
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3576
Unusual Site for a White Nodule on the Palatine Tonsil: Presentation, Differential Diagnosis, and Discussion
Published 2021-01-01“…For instance, the differential diagnosis of a white lesion on the palatine tonsil can range from benign to malignant lesions. Oral lymphoepithelial cysts commonly arise as painless, yellowish nodules on the floor of the mouth and the ventral or lateral surface of the tongue. …”
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3577
tRNA-Uridine Aminocarboxypropyltransferase DTW Domain Containing 2 Suppresses Colon Adenocarcinoma Progression
Published 2023-01-01“…Dysregulated expression of DTWD1 has been reported in several malignancies, nevertheless, the role of DTWD2 in cancers remains completely unknown. …”
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3578
Mechanisms by which Human Cells Bypass Damaged Bases during DNA Replication after Ultraviolet Irradiation
Published 2002-01-01“…The resulting chromosomal instability in surviving cells will contribute to malignant transformation.…”
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3579
Classification of Melanoma Cancer Using Deep Convolutional Neural Networks
Published 2024-12-01“…This study investigates the application of machine learning techniques to diagnose skin lesions, focusing on differentiating between benign moles and malignant melanoma. A Convolutional Neural Network (CNN) model was developed to explore machine learning's efficacy in this context. …”
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3580
miRNAs and Melanoma: How Are They Connected?
Published 2012-01-01“…It is characterized as a complex disease, originated from a malignant transformation of melanocytes. …”
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Article