Prevalence, presentation, risk factors and awareness of oral cancer: A systematic review of the Nigerian experience by Egbunah UP

“… Background: Oral cancers are malignant neoplasia of the lip and/or oral cavity that represent a major part of head and neck carcinomas (HNCs) along with laryngeal and pharyngeal carcinomas. …”
Get full text

Evolution of uncontrolled proliferation and the angiogenic switch in cancer by John D. Nagy, Dieter Armbruster

“…The major goal of evolutionary oncology is to explain how malignant traits evolve to become cancer 'hallmarks.' …”
Get full text

An Unusual Presentation of Streptococcus gallolyticus in Infective Endocarditis by Laura Torres Cruz, Maryam Barkhordarian, Neenu Antony, Muhammad Yasir, Sai Priyanka Pulipaka, Ahmad Al-Awwa, Sameh Elias

“…Through our case report, we emphasize the importance of investigating uncommon sources like cellulitis when initial malignant workup is negative in streptococcus bacteremia and further elucidate the pathophysiology of streptococcus bacterial dissemination from nonmalignancy-related sources.…”
Get full text

Premalignant Lesions in the Kidney by Ziva Kirkali, Kutsal Yorukoglu

“…Renal cell carcinoma (RCC) is the most malignant urologic disease. Different lesions, such as dysplasia in the tubules adjacent to RCC, atypical hyperplasia in the cyst epithelium of von Hippel-Lindau syndrome, and adenoma have been described for a number of years as possible premalignant changes or precursor lesions of RCC. …”
Get full text

Analysis of Signals Leading to Differentiation of Immature HL-60 after Administration of IL-4 by Simon Vassiliadis

“…At the same time, the same observation coupled with an increase in Mac-1, mature monocyte marker, is revealing ways to haematologists for converting malignant cases to normal situations. Based on previous reports that HLA-DR induction by IL-4 in the HL-60 system is mediated via the G-protein system (p21ras), this study was undertaken in order to define the intermediate signalling steps followed by this agent from the moment it is added to cultures to the differentiated cellular form obtained. …”
Get full text

Understanding the Role of Exercise in Nonalcoholic Fatty Liver Disease: ERS-Linked Molecular Pathways by Yong Zou, Zhengtang Qi

“…Exercise not only enhances hepatic tolerance to ERS but also prevents the malignant development of steatosis due to excessive ERS.…”
Get full text

Correlation analysis between disease mortality and public transportation coverage: The case of Taiwan by Wei-Ting Chen, Chung-Yu Chen

“…In addition, the negative correlation between the crude mortality rate of malignant neoplasms and the public transportation coverage during the same year in Yunlin County is −0.353, which is stronger than that for all nine regions considered, and its corresponding regression mode is valid, the β-coefficient, −0.894. …”
Get full text

Chemokines in Renal Diseases by Stephan Segerer, Peter J. Nelson

“…Therefore, it is not surprising that chemokines play important roles in a wide range of human diseases, including genetic immunodeficiencies, infections, autoimmune diseases, and malignant tumors. In this report, we have reviewed recent developments (since mid 2003) in chemokines in renal diseases. …”
Get full text

Early, integrated palliative care for people with chronic respiratory disease: lessons learnt from lung cancer by Anne M. Walker, Donald R. Sullivan, Phan Nguyen, Anne E. Holland, Natasha Smallwood

“…Lung cancer and chronic non-malignant respiratory disease cause pervasive, multifactorial suffering for patients and informal carers alike. …”
Get full text

Identifying Safeguards Disabled by Epstein-Barr Virus Infections in Genomes From Patients With Breast Cancer: Chromosomal Bioinformatics Analysis by Bernard Friedenson

“…EBV-transformed human mammary cells accelerate breast cancer when transplanted into immunosuppressed mice, but the virus can disappear as malignant cells reproduce. If this model applies to human breast cancers, then they should have genome damage characteristic of EBV infection. …”
Get full text

The Application of Convolutional Neural Network Combined with Fuzzy Algorithm in Colorectal Endoscopy for Tumor Assessment by Te-Jen Su, Feng-Chun Lee, Cheuk-Kwan Sun, Fu-Xiang Ke, Shih-Ming Wang, Ming-Chih Huang

“…The endoscopic images of the colon, which were classified into three categories of healthy (normal), benign tumor, and malignant tumor, were adopted as training data. When this method is combined with the patient’s physical data, the risk cancer can be calculated by the fuzzy algorithm. …”
Get full text

Pneumocystis carinii: A Review of an Important Opportunistic Pathogen in AIDS by M John Gill, Ron Read

“…Individuals with damaged T helper cells secondary to malignancies (eg, Hodgkin’s lymphoma), drugs (eg, cyclosporine, steroids), or certain infections (eg, human immunodeficiency virus) are at particular risk. …”
Get full text

Molecular Imaging of IGF-1R in Cancer by Yingying Sun PhD, Xilin Sun PhD, Baozhong Shen MD, PhD

“…The important role of insulin-like growth factor 1 receptor (IGF-1R) in malignant tumors has been well established. Increased IGF-1R activity promotes cancer cell proliferation, migration, and invasion and is associated with tumor metastasis, treatment resistance, poor prognosis, and shortened survival in patients with cancer. …”
Get full text

Long-Term Follow-Up in Children with Anisocoria: Cocaine Test Results and Patient Outcome by Fabienne C. Fierz, Christina Gerth-Kahlert

“…In most children with anisocoria and a positive cocaine test result, systemic investigation did not reveal any underlying etiology. The only malignant disease was diagnosed in a patient with a suspicion of Horner’s syndrome but with an inconclusive cocaine test result in our cohort.…”
Get full text

Malakoplakia associated with diarrhoea and colonic lesions after rituximab treatment by Yaqoub Alshatti, Meshaan Alenezi

“…Malakoplakia is a rare granulomatous condition that occurs due to defective lysosomal digestion during phagocytosis and can mimic inflammatory bowel disease (IBD) or malignancies, particularly in immunosuppressed patients. …”
Get full text

Pretreatment Thrombocytosis as a Prognostic Factor in Metastatic Breast Cancer by Athina Stravodimou, Ioannis A. Voutsadakis

“…An elevated platelet count is often associated with malignancies, and it has been confirmed as an adverse prognostic factor in various cancers including early stage breast cancer. …”
Get full text

Investigation of Doxorubicin Efficiency in Some Hematological Parameters in Women with Breast Cancer in Iraq by Hanan B. Saadon

“…Hematologic studies are thus very relevant in breast cancer management, its progression, and also in detection of some sequential malignancies related to breast cancer. …”
Get full text

Comparison of frontal QRS-T angle in mitral valve prolapse without arrhythmic phenotype with healthy individuals by Celal Kilit

“…The frontal QRS-T angle is a new indicator, related to malign arrhythmias and cardiac death risk in various diseases. …”
Get full text

The Role of mTOR Inhibitors in Liver Transplantation: Reviewing the Evidence by Goran B. Klintmalm, Björn Nashan

“…Despite the success of liver transplantation, long-term complications remain, including de novo malignancies, metabolic syndrome, and the recurrence of hepatitis C virus (HCV) and hepatocellular carcinoma (HCC). …”
Get full text

Ovarian Epithelial Cancer Stem Cells by Irena Conic, Irena Dimov, Desanka Tasic-Dimov, Biljana Djordjevic, Vladisav Stefanovic

“…The etiology and early events in the progression of these carcinomas are among the least understood of all major human malignancies. Compared to the CSCs of other cancer types, the identification and study of EOC stem cells (EOCSCs) is rather difficult due to several major obstacles: the heterogeneity of tumors comprising EOCs, unknown cells of origin, and lack of knowledge considering the normal ovarian stem cells. …”
Get full text