Oral Oncology: Two elective courses for advanced undergraduates - An Argentine teaching experience by Gerardo Gilligan, María Fernanda Galindez Costa, Eduardo Piemonte, Jerónimo Lazos, René Panico

“…This study presents our experience with an innovative undergraduate program focusing on Oral Oncology and Oral Potentially Malignant Disorders. Two elective courses were integrated into the curriculum, featuring contributions from Oral Medicine and Pathology experts across several Latin American countries via virtual platforms. …”
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TRIZ Theory and the Method of Cancer Document Selection for Chemical Complexes and Innovation Schemes of Meta-Analysis with Lymphomas as an Example by Yan Huiquan, Lyu Penghui, Wang Ling, Yu Zhiming

“…In the face of the growing incidence of malignant tumors (about 3.929 million, data issued in January 2019) and the death rate (about 2.338 million, data issued in January 2019) and the limitation of the application of informatics in cancer treatment, this paper tried to use TRIZ theory to deduce new ideas about cancer treatments, perform literature analysis on schemes, and make retrieval strategy for meta-analyses on cancer therapy. …”
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Protective Effects of Chronic Intermittent Hypobaric Hypoxia Pretreatment against Aplastic Anemia through Improving the Adhesiveness and Stress of Mesenchymal Stem Cells in Rats by Jing Yang, Li Zhang, Handong Wang, Zan Guo, Yixian Liu, Yi Zhang, Chuan Wang, Quanhai Li

“…Aplastic anemia (AA) is a common malignant blood disease, and chronic intermittent hypobaric hypoxia (CIHH) has a beneficial effect against different diseases. …”
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PPAR-γ Agonists and Their Effects on IGF-I Receptor Signaling: Implications for Cancer by A. Belfiore, M. Genua, R. Malaguarnera

“…It is now well established that the development and progression of a variety of human malignancies are associated with dysregulated activity of the insulin-like growth factor (IGF) system. …”
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Hepatic sinusoidal obstruction syndrome (SOS) associated with checkpoint inhibitor therapy by Marianna Litterio, Nicole Marchetti, Francesco Carubbi, Marianna Tudini, Luciano Mutti, Claudio Ferri

“…Recently, immune checkpoint inhibitors (ICIs) have revolutionised the treatment of many solid organ malignancies. Furthermore, as their use has become more widespread, rare toxicities have emerged. …”
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Amino Acid-Mediated Metabolism: A New Power to Influence Properties of Stem Cells by Jilan Liu, Xianyun Qin, Dongfeng Pan, Bin Zhang, Feng Jin

“…The balance in AA metabolism is responsible for maintaining the functionality of noncancer stem cells, and altering the levels of AAs can influence the malignant biological behavior of cancer stem cells. …”
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Recent Insights into Antibiotic Resistance in Helicobacter pylori Eradication by Wenming Wu, Yunsheng Yang, Gang Sun

“…Antibiotics have been useful in the treatment of H. pylori-related benign and malignant gastroduodenal diseases. However, emergence of antibiotic resistance often decreases the eradication rates of H. pylori infections. …”
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Deep learning-integrated MRI brain tumor analysis: feature extraction, segmentation, and Survival Prediction using Replicator and volumetric networks by Deependra Rastogi, Prashant Johri, Massimo Donelli, Seifedine Kadry, Arfat Ahmad Khan, Giuseppe Espa, Paola Feraco, Jungeun Kim

“…Abstract The most prevalent form of malignant tumors that originate in the brain are known as gliomas. …”
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Costello Syndrome and Umbilical Ligament Rhabdomyosarcoma in Two Pediatric Patients: Case Reports and Review of the Literature by Carlos Sánchez-Montenegro, Alejandra Vilanova-Sánchez, Saturnino Barrena-Delfa, Jair Tenorio, Fernando Santos-Simarro, Sixto García-Miñaur, Pablo Lapunzina, Leopoldo Martínez-Martínez

“…Costello syndrome is a poorly known disorder in pediatric oncology but their predisposition to malignancies implies the need for a new perspective on early diagnosis and aggressive medical and surgical treatment.…”
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Dynamic Metabolic Changes during the First 3 Months after 90Y-Ibritumomab Tiuxetan Radioimmunotherapy by Miwako Takahashi, Toshimitsu Momose, Keitaro Koyama, Motoshi Ichikawa, Mineo Kurokawa, Kuni Ohtomo

“…To elucidate the time course of tumor metabolism during the first 3 months after 90Y-ibritumomab tiuxetan radioimmunotherapy (RIT) in patients with refractory malignant lymphoma. Materials and Methods. Seven patients with recurrent follicular lymphoma underwent FDG-PET imaging before and after 1-, 4-, and 12-week RIT with 90Y-ibritumomab tiuxetan. …”
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Loss of Sirtuin 7 impairs cell motility and proliferation and enhances S-phase cell arrest after 5-fluorouracil treatment in head and neck cancer by Marta Halasa, Syeda Afshan, Anna Wawruszak, Agata Borkowska, Klaudia Brodaczewska, Alicja Przybyszewska-Podstawka, Joanna Kalafut, Marzena Baran, Adolfo Rivero-Müller, Andrzej Stepulak, Matthias Nees

“…Abstract Sirtuin 7 (SIRT7), a member of the sirtuin family of NAD+-dependent deacetylases, plays a vital role in cancer, exhibiting context-dependent functions across various malignancies. Our study investigates the role of SIRT7 depletion in head and neck squamous cell carcinoma (HNSCC) progression. …”
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Metastatic Prostate Cancer to the Left Temporal Bone: A Case Report and Review of the Literature by Erynne A. Faucett, Hal Richins, Rihan Khan, Abraham Jacob

“…Breast, lung, and prostate cancers are the three most common malignancies to metastasize to the temporal bone. Still, metastatic prostate cancer of the temporal bone is a rare finding, with approximately 21 cases reported in the literature and only 2 cases discovered more than 10 years after initial treatment of the primary. …”
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Stem Cell Hierarchy and Clonal Evolution in Acute Lymphoblastic Leukemia by Fabian Lang, Bartosch Wojcik, Michael A. Rieger

“…Acute lymphoblastic leukemia (ALL) is a highly malignant cancer of the lymphoid system in the bone marrow with a dismal prognosis after relapse. …”
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Plasmacytoid Urothelial Carcinoma of the Bladder Metastatic to the Stomach: A Case Report by Philippe Nabbout, James Furr, Murugan Paari, Gennady Slobodov

“…Rereadings revealed that the initial bladder and gastric malignancies were also plasmacytoid carcinoma, indicating that, the patient had since 2004, a PUC of the bladder that spread to the stomach and peritoneal cavity. …”
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Lymphomatoid Granulomatosis Treated Successfully with Rituximab in a Renal Transplant Patient by Cindy Castrale, Wael El Haggan, Françoise Chapon, Oumedaly Reman, Thierry Lobbedez, Jean Philippe Ryckelynck, Bruno Hurault de Ligny

“…Lymphomatoid granulomatosis (LYG) in renal transplant recipients is rare multisystemic angiocentric lymphoproliferative disorder with significant malignant potential. Here, we describe LYG in a 70-year-old renal allograft recipient who, 4 years after transplantation, on tacrolimus and mycophenolate mofetil and prednisone maintenance immunosuppression, complained of low-grade fever, persistent headache and gait disturbance. …”
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Establishing a radiomics model using contrast-enhanced ultrasound for preoperative prediction of neoplastic gallbladder polyps exceeding 10 mm by Dong Jiang, Yi Qian, Yijun Gu, Ru Wang, Hua Yu, Zhenmeng Wang, Hui Dong, Dongyu Chen, Yan Chen, Haozheng Jiang, Yiran Li

“…CEUS has a high accuracy rate in diagnosing the benign or malignant nature of gallbladder space-occupying lesions, which can significantly reduce the preoperative waiting time for related examinations and provide more reliable diagnostic information for clinical practice. …”
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Monoamine neurotransmitters in breast cancer: Progression, immunomodulation, and therapeutic strategies by Saeed Mahdianipur, Mahafarin Maralani, Homa Davoodi

“…They also affect peripheral tissues and inflammation, playing a crucial role in the biology of various malignancies, including breast cancer, the most common cancer among women worldwide. …”
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PPARγ as a Novel Therapeutic Target in Lung Cancer by Aravind T. Reddy, Sowmya P. Lakshmi, Raju C. Reddy

“…Its involvement in adipocyte differentiation and glucose and lipid homeostasis is well-recognized, but accumulating evidence now suggests that PPARγ may also function as a tumor suppressor, inhibiting development of primary tumors and metastases in lung cancer and other malignancies. Besides having prodifferentiation, antiproliferative, and proapoptotic effects, PPARγ agonists have been shown to prevent cancer cells from acquiring the migratory and invasive capabilities essential for successful metastasis. …”
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Clinicopathological study of masses of nasal cavity and paranasal sinuses and its correlation with radiology by Soumya Sahu, Garima Malpani, Amit V. Varma, Kamal Malukani, Bela Sharda

“…Results: Among the 128 cases examined, 98 (76.56%) were identified as non-neoplastic lesions, 14 (10.93%) as benign neoplasms, and 16 (12.50%) as malignant lesions through HPE. The male-to-female ratio stood at 1.2:1. …”
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Imaging Reporters for Proteasome Activity Identify Tumor- and Metastasis-Initiating Cells by Amanda C. Stacer, Hanxiao Wang, Joseph Fenner, Joseph S. Dosch, Anna Salomonnson, Kathryn E. Luker, Gary D. Luker, Alnawaz Rehemtulla, Brian D. Ross

“…Tumor-initiating cells, also designated as cancer stem cells, are proposed to constitute a subpopulation of malignant cells central to tumorigenesis, metastasis, and treatment resistance. …”
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