Discrimination of Melanoma Using Laser-Induced Breakdown Spectroscopy Conducted on Human Tissue Samples by Muhammad Nouman Khan, Qianqian Wang, Bushra Sana Idrees, Geer Teng, Xutai Cui, Kai Wei

“…The results revealed that LIBS combined with chemometric methods for detection and discrimination of human malignancies is a reliable, accurate, and precise technique.…”
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Acute Tracheal Obstruction Secondary to Cervical Liposarcoma Metastasis by Haoyu Chen, Song Zhang, Haining Zhou

“…A CT scan detected an endotracheal mass causing significant obstruction, suspected to be malignant. The patient required intensive care due to respiratory distress. …”
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Primary Pure Squamous Cell Carcinoma of the Gallbladder Locally Invading the Liver, Duodenum, and Stomach: A Case Report and Literature Review by Aldrin C. Alpuerto, Maximo E. Mora, R. Jonathan Robitsek, Sebastian D. Schubl

“…Histologic evaluation of the resected mass revealed a malignant tumor with prominent keratinization, confirming the diagnosis of an invasive primary pure SCC of the gallbladder. …”
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Diagnosis and Management of Freeman-Burian Syndrome: A Case Report by Aidin Arabzadeh, Hossein Azaditalab, Hesam Alitaleshi, Mohammad Reza Abbaszadeh

“…   Abstract: Introduction: Freeman Sheldon syndrome is a rare genetic disease of varying severity with craniocarpotarsal manifestations, which has many difficulties in orthopedic management also anaesthetic concerns about intubation difficulties and malignant hyperthermia and mutch tendency of deformities for recurrence. …”
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Ovarian Fibroma as a Possible Cause of Fever of Unknown Origin by İkbal Kaygusuz, Ayla Eser, İlknur İnegöl Gümüş, İsmail Kırbaş, Kayıhan Akın, Hacer Haltas, Hasan Kafalı

“…She had a comprehensive work-up for FUO, including rheumatologic, infectious, and malignant etiologies. Magnetic resonance imaging (MRI) scans of the pelvis showed two well defined ovarian lesions, which were suggestive of an ovarian fibroma. …”
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Changes in Cytokines of the Bone Microenvironment during Breast Cancer Metastasis by Donna M. Sosnoski, Venkatesh Krishnan, William J. Kraemer, Courtenay Dunn-Lewis, Andrea M. Mastro

“…It is commonly accepted that cancer cells interact with host cells to create a microenvironment favoring malignant colonization. The complex bone microenvironment produces an ever changing array of cytokines and growth factors. …”
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Disseminated nocardiosis in a patient with AIDS and B-cell non-Hodgkin’s lymphoma: a case report by Delvis R. Reverón, David M. Flora-Noda, Lily M. Soto, Maribel Dolande, Juan Frey, Aleiram Chaurio, Bárbara D. Ruiz-Alayón, Jocays Caldera, Fhabián S. Carrión-Nessi, David A. Forero-Peña

“…Abstract Background Disseminated nocardiosis is a rare and potentially fatal disease, with a higher incidence in immunocompromised patients, such as those living with human immunodeficiency virus (HIV) or hematological malignancies, including lymphoma. Information on Nocardia spp. infection in Venezuela is limited. …”
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Fallopian Tube Hemangioma Discovered on Follow-up for Uterine Leiomyoma by Dmitrii SUMTSOV, Georgii SUMTSOV, Natalia HYRIAVENKO, Mykola LYNDIN, Kateryna SIKORA, Volodymyr KOLYSHKIN, Yulia REDKO, Igor GLADCHUK

“…Incorrect interpretation of a benign tumor at a young age can lead to unnecessary radical surgery with a resulting loss of fertility, and an unrevealed malignant process can threaten life.…”
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Targeting autophagy to enhance chemotherapy and immunotherapy in oral cancer by Xiaoli Zeng, Xiaoli Zeng, Xiaoli Zeng, Yue Chen, Yue Chen, Jing Wang, Jing Wang, Miao He, Miao He, Junyao Qiu, Yun Huang

“…Oral cancer is a highly malignant disease characterized by recurrence, metastasis, and poor prognosis. …”
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Persistent Polyclonal B Cell Lymphocytosis B Cells Can Be Activated through CD40-CD154 Interaction by Emmanuelle Dugas-Bourdages, Sonia Néron, Annie Roy, André Darveau, Robert Delage

“…The clinical course is usually benign, but it is not known whether or not PPBL might be part of a process leading to the emergence of a malignant proliferative disorder. In this study we sought to investigate the functional response of B cells from patients with PPBL by use of an optimal memory B cell culture model based on the CD40-CD154 interaction. …”
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Potential Target Antigens for a Universal Vaccine in Epithelial Ovarian Cancer by Renee Vermeij, Toos Daemen, Geertruida H. de Bock, Pauline de Graeff, Ninke Leffers, Annechien Lambeck, Klaske A. ten Hoor, Harry Hollema, Ate G. J. van der Zee, Hans W. Nijman

“…The prognosis of epithelial ovarian cancer (EOC), the primary cause of death from gynaecological malignancies, has only modestly improved over the last decades. …”
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MicroRNAs as Haematopoiesis Regulators by Ram Babu Undi, Ravinder Kandi, Ravi Kumar Gutti

“…Aberrant expression of miRNAs was observed in hematological malignancies including chronic myelogenous leukemia, chronic lymphocytic leukemia, multiple myelomas, and B cell lymphomas. …”
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Current Trends in Targeted Therapies for Glioblastoma Multiforme by Fumiharu Ohka, Atsushi Natsume, Toshihiko Wakabayashi

“…Glioblastoma multiforme (GBM) is one of the most frequently occurring tumors in the central nervous system and the most malignant tumor among gliomas. Despite aggressive treatment including surgery, adjuvant TMZ-based chemotherapy, and radiotherapy, GBM still has a dismal prognosis: the median survival is 14.6 months from diagnosis. …”
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TNG908 is a brain-penetrant, MTA-cooperative PRMT5 inhibitor developed for the treatment of MTAP-deleted cancers by Kimberly J. Briggs, Kevin M. Cottrell, Matthew R. Tonini, Alice Tsai, Minjie Zhang, Douglas A. Whittington, Wenhai Zhang, Steven A. Lombardo, Satoshi Yoda, Erik W. Wilker, Samuel R. Meier, Yi Yu, Teng Teng, Alan Huang, John P. Maxwell

“…Strong preclinical activity in multiple MTAP-deleted xenograft models, as well as demonstrated brain penetrance in preclinical models, support the potential for histology-agnostic clinical development of TNG908 in MTAP-deleted solid tumors, including CNS malignancies. TNG908 is being tested clinically in patients with MTAP-deleted tumors, including glioblastoma, in a Phase I/II clinical trial (NCT05275478).…”
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Disseminated Exfoliative Dermatitis Associated with All-Transretinoic Acid in the Treatment of Acute Promyelocytic Leukemia by Yonal Ipek, Dogru Hulya, Aktan Melih

“…All-trans retinoic acid (ATRA) is a subgroup of the retinoid family, which induces complete remission (CR) in APL by causing differentiation and apoptosis in immature malignant promyelocytes rather than inducing cell death by cytotoxicity (Warrell et al. (1993), Liu et al. (2000), and Cassinat et al. (2001)). …”
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Treatment of Liver Metastases in Patients with Neuroendocrine Tumors of Gastroesophageal and Pancreatic Origin by Ping Gu, Jennifer Wu, Elliot Newman, Franco Muggia

“…Well-to-moderately differentiated neuroendocrine tumors of gastroesophageal and pancreatic origin (GEP-NETs) with liver metastasis are a heterogeneous group of malignancies for which a range of therapeutic options have been employed. …”
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Preparation of Ca-Mg Double-Doped Mesoporous Silica Nanoparticles and Their Drug-Loading and Drug-Releasing Properties by Qian Zhang, Jiamin Huang, Chao Liu, Ruihua Chen, Tao Jiang, Yusufu Hailili, Telieke Bahetibieke, Xiaohui Tang, Mei Wang

“…Breast cancer is a common clinical malignant tumor that seriously threatens women’s physical and mental health. …”
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The Interactions between Insulin and Androgens in Progression to Castrate-Resistant Prostate Cancer by Jennifer H. Gunter, Amy A. Lubik, Ian McKenzie, Michael Pollak, Colleen C. Nelson

“…Androgen-dependant gene pathways regulate the growth and maintenance of both normal and malignant prostate tissue, and androgen-deprivation therapy (ADT) in patients exploits this dependence when used to treat recurrent and metastatic prostate cancer resulting in tumour regression. …”
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Aqp 9 and Brain Tumour Stem Cells by Guri Fossdal, Einar O. Vik-Mo, Cecilie Sandberg, Mercy Varghese, Mari Kaarbø, Emily Telmo, Iver A. Langmoen, Wayne Murrell

“…Several studies have implicated the aquaporins (aqp) 1, 4, and 9 in the pathogenesis of malignant brain tumours, suggesting that they contribute to motility, invasiveness, and oedema formation and facilitate metabolism in tumour cells under hypoxic conditions. …”
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Brain-targeting drug delivery systems: The state of the art in treatment of glioblastoma by Bo Sun, Rong Li, Ning Ji, Han Liu, Hongxiang Wang, Chao Chen, Long Bai, Jiacan Su, Juxiang Chen

“…Glioblastoma (GBM) is the most prevalent primary malignant brain tumor, characterized by a high mortality rate and a poor prognosis. …”
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