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3401
Altered Expression of Cellular Bcl-2 in the Progression of Hamster Cholangiocarcinogenesis
Published 2012-01-01“…Bcl-2 is an intracytoplasmic and membrane-associated apoptosis suppressor, and its overexpression is closely associated with survival of malignant tumors, in particular their aggressive behavior and poor prognosis. …”
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3402
Circumscribed Morphea and Breast Asymmetry in an Adolescent
Published 2014-01-01“…It can mimic benign and malignant breast disorders justifying the benefit for early tissue biopsy. …”
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3403
A Radiograph Dataset for the Classification, Localization, and Segmentation of Primary Bone Tumors
Published 2025-01-01“…Abstract Primary malignant bone tumors are the third highest cause of cancer-related mortality among patients under the age of 20. …”
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3404
Cellular Senescence as a Target in Cancer Control
Published 2011-01-01“…Recent findings suggest that cellular senescence is a natural mechanism to prevent undesired oncogenic stress in somatic cells that has been lost in malignant tumors. Given that the ultimate goal of cancer research is to find the definitive cure for as many tumor types as possible, exploration of cellular senescence to drive towards antitumor therapies may decisively influence the outcome of new drugs. …”
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3405
BIOMARKERS, NEOANGIOGENESIS AND GROWTH FACTORS IN PANCREATIC CANCER
Published 2019-09-01“…Pancreatic cancer (PC) is a lethal malignant tumor characterized by a rapid progression, invasiveness and resistance to radiochemotherapy. …”
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3406
Characterization of a pleomorphic rhabdomyosarcoma cell line
Published 2025-01-01“…Results of the novel functional BH1522 tests corroborate published tumor sequencing data that demonstrated alterations in receptor tyrosine kinase/MAPK, PI3K/AKT and mutated p53 as suspected drivers of malignant growth.…”
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3407
Serum CEACAM1 Elevation Correlates with Melanoma Progression and Failure to Respond to Adoptive Cell Transfer Immunotherapy
Published 2015-01-01“…Malignant melanoma is a devastating disease whose incidences are continuously rising. …”
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3408
The amount of DNA and RNA in primary cancer cells and their metastases
Published 2024-08-01“…The aim of this study is to determine the content of DNA and RNA in cells of primary cancer and its metastases through microspectrophotometric analysis of malignant cells collected from 30 patients with primary and metastatic oncological processes. …”
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3409
Emerging nanomedicine strategies for hepatocellular carcinoma therapy
Published 2024-09-01“…Abstract Hepatocellular carcinoma (HCC) is a prevalent malignant tumor with a range of risk factors, including viral infections, alcoholic liver disease, exposure to fungal toxins, obesity, and type 2 diabetes. …”
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3410
Hypopigmented mycosis fungoides: an important differential diagnosis of hypochromias in childhood
Published 2025-01-01“…Early recognition of HMF is crucial for proper management and to avoid complications associated with malignant evolution.…”
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3411
Combined Effect of Lentinan and Cisplatin on Cytokines IL-6, TNF-α, and TGF-β in Tumor Therapy
Published 2019-01-01“…Many cytokines have shown positive effect on different malignancies in clinical trials. Studies have shown that such cytokines as IL6, TNF-α, and TGF-β play a quite important role in the formation of tumor microenvironment. …”
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3412
Bilateral reconstruction of the mandibular body with symphyseal preservation using a single fibula free flap: operative technique
Published 2022-07-01“…Abstract Background Mandibular osteonecrosis may occur in 5% of the patients who undergo radiotherapy for the treatment of head and neck malignancies. Resection and microvascular reconstruction is the treatment of choice in complicated osteoradionecrosis, however multifocal presentation may complicate the management of the disease given the poor quality and limited availability of adequate recipient vessels. …”
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3413
Vulvar Metastasis in Renal Cell Carcinoma: A Case Report Highlighting the Aggressive Nature of Clear Cell Renal Cell Carcinoma
Published 2024-12-01“…Vulvar cancer is one of the rarest gynecological malignancies. The development of this condition can be associated with either dysplasia linked to human papillomavirus (HPV), primarily affecting younger women, or vulvar dermatoses such as lichen sclerosus, which predominantly affect older women. …”
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3414
MicroRNAs in pancreatic cancer drug resistance: mechanisms and therapeutic potential
Published 2025-01-01“…Pancreatic cancer (PC) remains one of the most lethal malignancies, primarily due to its intrinsic resistance to conventional therapies. …”
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3415
A Lip Lump: An Unexpected Histological Diagnosis of a Lip Schwannoma
Published 2017-01-01“…If recurrence does occur one needs to consider whether complete enucleation was achieved or whether malignant transformation has occurred.…”
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3416
Focused ultrasound for treatment of peripheral brain tumors
Published 2023-04-01“…Malignant brain tumors are the leading cause of cancer-related death in children and remain a significant cause of morbidity and mortality throughout all demographics. …”
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3417
The molecular mechanism of gemcitabine in inhibiting the HIF-1α/VEGFB/FGF2/FGFR1 signaling pathway for ovarian cancer treatment
Published 2025-01-01“…Abstract Ovarian cancer is a common malignant tumor in women, exhibiting a certain sensitivity to chemotherapy drugs like gemcitabine (GEM). …”
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3418
Sirtuin 1: A Dilemma in Transplantation
Published 2020-01-01“…However, the potential ability of sirtuin 1 to induce malignancies raises some concerns about its overexpression in clinic. …”
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3419
Successful Modified Therapy in a Patient with Probable Infection-Associated Hemophagocytic Lymphohistiocytosis
Published 2019-01-01“…In adults, HLH is typically a complication of infections, autoimmune diseases, and malignancies. While the disease is often fatal, classic management of HLH revolves around early diagnosis and initiation of protocolized therapy. …”
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3420
Detection of breast cancer lesions using APT weighted MRI: a systematic review
Published 2025-01-01“…APT MRI had the ability to distinguish between benign and malignant lesions with an AUC as high as 0.959. There is a positive correlation between APT signal intensity and tumor grade/stage as well as Ki-67, whereas no correlation was found with ER/PR/Her-2 receptor status. …”
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