Promising Remission with Reduced Bevacizumab and Pembrolizumab Dosage in a Patient with AT-rich Interaction Domain 1A Mutated Ovarian Clear-cell Carcinoma Refractory to Chemotherap... by Cheng-Wei Huang, Ruo-Han Tseng

“…Immune checkpoint inhibitors may play a new role in the treatment of these malignancies. Genetic analyses revealed a significant proportion of ovarian clear-cell carcinoma carrying the AT-rich interaction domain 1A protein (ARID1A) mutation. …”
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Biology of extracellular vesicles and the potential of tumor-derived vesicles for subverting immunotherapy of cancer by Theresa L Whiteside

“…Plasma of patients with cancer contains variably elevated numbers of tumor-derived sEV called “TEX,” which differ from circulating sEV produced by non-malignant cells by the immunosuppressive phenotype and the molecular/genetic content. …”
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Clinicopathological Features of Inflammatory Myofibroblastic Tumor in the Breast by Shifei Liu, Rui Yuan, Yulan Jin, Chunyan He, Xingzheng Zheng, Yang Zhan

“…Inflammatory myofibroblastic tumor (IMT) is a mesenchymal spindle cell tumour with low malignant potential which is extremely rare in breasts. …”
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Hypovitaminosis D in patients with oral leukoplakia: insights from a cross-sectional study by Andrea Maturana-Ramirez, Andrea Maturana-Ramirez, Juan Aitken-Saavedra, Dante Mora-Ferraro, Gabriel Rojas-Zúñiga, Iris Espinoza-Santander, Gonzalo Rojas-Alcayaga, Ana Ortega-Pinto, Montserrat Reyes, Diego Lazo, Egardo Caamanão

“…This opens the possibility of future research on vitamin D as a chemopreventive agent in the malignant transformation of OL, and to evaluate the relationship between smoking and hypovitaminosis D.…”
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Resolution of oncogene-induced senescence markers in HPV-infected cervical cancer tissue by Ashraf I. Khasawneh, Sofian Al Shboul, Nisreen Himsawi, Amani Al Rousan, Nisreen Abu Shahin, Mohammed El-Sadoni, Ahmad Alhesa, Ala’ Abu Ghalioun, Suzan Khawaldeh, Bayan Shawish, Salem Abu Mahfouz, Mais Al-Shayeb, Shatha Abo Dawoud, Raghad Tlilan, Mohammad Nuseir, Moureq R. Alotaibi, Ola Abu Al Karsaneh, Fida Asali, Marcos Yébenes Mayordomo, Raghda Barham, Rame Khasawneh, Tareq Saleh

“…Similarly, Lamin B1 expression was observed in 89% of tumor cells in malignant tissue on average, compared to 60% in CIN samples. …”
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Integrated single-cell and bulk transcriptome analysis of R-loop score-based signature with regard to immune microenvironment, lipid metabolism and prognosis in HCC by Long Chen, Houzhi Yang, Xianfu Wei, Xianfu Wei, Jianchao Liu, Xiuxin Han, Chao Zhang, Yongheng Liu, Yan Zhang, Yao Xu, Yiqin Li, Guowen Wang, Jinyan Feng

“…Dysregulated R-loops, three-stranded nucleic acid structures associated with genome instability, play a key role in the malignant characteristics of various tumors. However, the detailed role and mechanism of R-loops in HCC progression remain elusive and require further exploration. …”
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Primary Gallbladder Small Lymphocytic Lymphoma as a Rare Postcholecystectomy Finding by Kyriakos Psarras, Nikolaos Symeonidis, Euthymia Vlachaki, Minas Baltatzis, Georgios Papatolios, Efstathios Pavlidis, Christina Mouratidou, Ioannis Venizelos, Theodoros Pavlidis, Athanasios Sakantamis, Christina Nikolaidou

“…In many of these cases the presenting symptoms were mimicking symptomatic gallstone disease and the diagnosis was made postoperatively, especially when the preoperative imaging results were far from suspicious for malignant disease. Patients and Methods. We report a case of primary lymphoma of the gallbladder in an 85-year-old man with gallstone disease, who was admitted for elective cholecystectomy 2 months after an episode of acute cholecystitis and pancreatitis. …”
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Bile Duct Adenoma with Oncocytic Features by E. J. Johannesen, Zihao Wu, Jason-Scott Holly

“…Oncocytic bile duct neoplasms are rare and the majority are malignant. A 61-year-old male with a diagnosis of colorectal adenocarcinoma was undergoing surgery when a small white nodule was discovered on the surface of the right lobe of his liver. …”
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Nocardiose disseminada by Tiago Costa, Luís Rocha, Luciana Silva, Inês Rato, Sara Pinto

“…Nocardiosis, caused by various species of Nocardia, poses diagnostic and therapeutic challenges due to its diverse clinical presentations that often mimic other infections and malignancies. We present the case of a 72-year-old woman with a history of autoimmune hepatitis and diabetes mellitus (DM) who initially presented with fever, headaches, and confusion. …”
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Multifocal Extranodal Involvement of Diffuse Large B-Cell Lymphoma by Devrim Cabuk, Y. Taha Gullu, Ilknur Basyigit, Ozgur Acikgoz, Kazım Uygun, Kursat Yildiz, Fusun Yildiz

“…Endobronchial involvement of extrapulmonary malignant tumors is uncommon and mostly associated with breast, kidney, colon, and rectum carcinomas. …”
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Establishment and characterization of three gemcitabine-resistant human intrahepatic cholangiocarcinoma cell lines by Jiandong Li, Yanxin Hu, Jiayao Zhang, Weiguang Zhang, Jianhua Yu, Baochun Lu

“…Abstract Intrahepatic cholangiocarcinoma (ICC) is a highly malignant liver tumor associated with a dismal prognosis, largely due to chemotherapy resistance. …”
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Lingual Thyroid Excision with Transoral Robotic Surgery by Elif Ersoy Callıoglu, Kazım Bozdemir, Bulent Ulusoy, Tolga Oguzhan, M. Hakan Korkmaz

“…Usually follow-up without treatment is preferred except for obstructive symptoms, bleeding, and suspicion of malignity. Main symptoms are dysphagia, dysphonia, bleeding, dyspnea, and obstructive sleep apnea. …”
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PRIMARY MULTIPLE MALIGNAT TUMORS MOST COMMON LOCALIZATIONS CANCER - CANCER STUDY CLINICS by G. V. Goncharenko

“…There were registered 1054 patients with malignant tumors. Of these 128 (12.14%) and had the PMN, of that number, 8 patients had triple the localization of cancer. …”
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The role of laminins in cancer pathobiology: a comprehensive review by Elena Nonnast, Emilia Mira, Santos Mañes

“…Understanding the complex roles of LMs in cancer biology, as well as their differential expression patterns in malignancies, could provide new diagnostic tools for predicting disease outcomes and pave the way for innovative therapeutic strategies, such as targeting LM-receptor interactions or modulating ECM dynamics to impede tumor growth and metastasis.…”
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CDCA7 enhances STAT3 transcriptional activity to regulate aerobic glycolysis and promote pancreatic cancer progression and gemcitabine resistance by Dijie Zheng, Yazhu Deng, Lu Deng, Zhiwei He, Xinghao Sun, Yanyu Gong, Binbin Shi, Deqin Lu, Chao Yu

“…Abstract Cell division cycle associated 7 (CDCA7) plays a role in various malignancies, especially pancreatic cancer (PC). However, its expression pattern and functional significance in PC require further research. …”
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SLE and Non-Hodgkin’s Lymphoma: A Case Series and Review of the Literature by Prajwal Boddu, Abdul S. Mohammed, Chandrahasa Annem, Winston Sequeira

“…Lymphoma represents a relatively well-recognized malignant phenomenon associated with lupus. The cause and effect relationships of lymphoma in SLE have been subject to extensive scrutiny with several studies reporting on clinic-pathologic characteristics and risk factors predicting lymphoma development in SLE. …”
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Unveiling DNA methylation: early diagnosis, risk assessment, and therapy for endometrial cancer by Minzhen Li, Minzhen Li, Zhili Xia, Ruiyu Wang, Ruiyu Wang, Mingrong Xi, Mingrong Xi, Minmin Hou, Minmin Hou

“…Endometrial cancer (EC), one of the most common gynecologic malignancies worldwide, poses a significant burden particularly among young women, with poor treatment outcomes and prognosis for advanced and recurrent patients. …”
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Transplant oncology and anti-cancer immunosuppressants by Dejun Kong, Jinliang Duan, Shaofeng Chen, Zhenglu Wang, Zhenglu Wang, Jiashu Ren, Jianing Lu, Tao Chen, Zhuolun Song, Di Wu, Yuan Chang, Zhongqian Yin, Zhongyang Shen, Zhongyang Shen, Zhongyang Shen, Zhongyang Shen, Hong Zheng, Hong Zheng, Hong Zheng, Hong Zheng

“…However, long-term immunosuppressive therapy is required to prevent allogeneic graft rejection, which inadvertently elevates the risk of post-transplant malignancies, especially for liver transplant recipients with a prior history of liver cancer. …”
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MYST3/CREBBP Rearranged Acute Myeloid Leukemia after Adjuvant Chemotherapy for Breast Cancer by Arjun Gupta, Mrinal M. Patnaik, Harris V. Naina

“…Although rare, clinicians and patients must be aware that therapy related malignancies, specifically acute myeloid leukemia (AML), can occur as a complication of adjuvant chemotherapy for breast cancer. …”
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Fecaloma causing small bowel obstruction in the absence of risk factors: a case report by Youssef Ahmad, Umer Siddiqui, Ayman Ahmed, Aiswarya Sudheer, Tejaswi Chetla, Inayat Shergill, Fadi Souleiman

“…Abstract Background Small bowel obstruction is a common surgical emergency typically caused by adhesions, hernias, and malignancies. However, ileal fecalomas represent an exceptionally rare etiology, with few cases reported in literature. …”
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