Recent Progress of Genome Study for Anaplastic Thyroid Cancer by Jieun Lee, Jung-Ah Hwang, Eun Kyung Lee

“…Anaplastic thyroid cancer (ATC) belongs to the most malignant and rapidly progressive human thyroid cancers and its prognosis is very poor. …”
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Cytogenetic Evolution of Human Ovarian Cell Lines Associated with Chemoresistance and Loss of Tumorigenicity by Stéphanie Struski, Martine Doco‐Fenzy, Michael Koehler, Ilse Chudoba, Francis Levy, Linda Masson, Nicole Michel, Evelyne Ulrich, Nadine Gruson, Jean Bénard, Gérard Potron, Pascale Cornillet‐Lefebvre

“…In order to identify genomic changes associated with a resistant phenotype acquisition, we used comparative genomic hybridization (CGH) to compare a human ovarian cell line, Igrov1, and four derived subcell lines, resistant to vincristine and presenting a reversion of malignant properties. Multicolor FISH (Multiplex‐FISH and Spectral Karyotype) and conventional FISH are also used to elucidate the karyotype of parental cell line. …”
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A Lightweight Convolutional Neural Network for Classification of Brain Tumors Using Magnetic Resonance Imaging by Mahir Kaya, Alper Özatılgan

“…Of these diseases, the deadliest is undoubtedly the brain tumor, which can occur in all age groups and can be benign or malignant. Therefore, early diagnosis and prognosis are very important. …”
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I see double! Searching for the abnormal cranial nerve in diplopia by Angela Guarnizo, Carlos Torres

“…Infections, inflammatory, vascular, degenerative, traumatic, iatrogenic and malignant pathologies can cause diplopia. The combination of medical history, physical examination and imaging is crucial for an accurate diagnosis. …”
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Depletion of Regulatory T Cells in a Mouse Experimental Glioma Model through Anti-CD25 Treatment Results in the Infiltration of Non-Immunosuppressive Myeloid Cells in the Brain by Wim Maes, Tina Verschuere, Anaïs Van Hoylandt, Louis Boon, Stefaan Van Gool

“…The recruitment and activation of regulatory T cells (Tregs) in the micro-environment of malignant brain tumors has detrimental effects on antitumoral immune responses. …”
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Cancer stem-like cells stay in a plastic state ready for tumor evolution by Jiali Xu, Houde Zhang, Zhihao Nie, Wenyou He, Yichao Zhao, Zhenhui Huang, Lin Jia, Zhiye Du, Baotong Zhang, Siyuan Xia

“…Generally, CSCs come from the malignant transformation of somatic stem cells or the de-differentiation of other cancer cells. …”
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What should every doctor know about ocular melanoma? - review of literature by Aleksandra Grzegorczyk, Magdalena Pachla, Ewa Mazur

“… The following paper aims to discuss melanoma located in the eye. Melanoma is a malignant tumor arising from melanocytes, in which a mutation has occurred in the DNA and pathological cells have developed. …”
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Novel Therapies for Aggressive B-Cell Lymphoma by Kenneth A. Foon, Kenichi Takeshita, Pier L. Zinzani

“…Aggressive B-cell lymphoma (BCL) comprises a heterogeneous group of malignancies, including diffuse large B-cell lymphoma (DLBCL), Burkitt lymphoma, and mantle cell lymphoma (MCL). …”
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Postmastectomy-Postirradiation Atypical Vascular Lesion of the Skin: Report of 2 Cases by P. S. Jayalakshmy, Aswathy P. Sivaram, Joy Augustine, P. Bindu

“…The spectrum of vascular lesions developing in breast or chest wall skin following lumpectomy or mastectomy and radiation is wide and ranges from atypical vascular lesions with a benign clinical behaviour to frankly malignant, angiosarcoma ranging histologically from well to poorly differentiated variety. …”
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Intracorneal Hematoma Showing Clinical and Dermoscopic Features of Acral Lentiginous Melanoma by Ugur Uslu, Franz Heppt, Michael Erdmann

“…Since clinical and dermoscopic examinations did not rule out a malignant skin lesion, surgical excision was performed and confirmed an intracorneal hematoma. …”
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TMEM100 Modulates TGF-β Signaling Pathway to Inhibit Colorectal Cancer Progression by Huixia Li, Chuan Cheng, Weibo You, Jiujian Zheng, Jie Xu, Peng Gao, Jianping Wang

“…Overexpression of TMEM100 inhibited the activation of the TGF-β signaling pathway, thus inhibiting malignant progression of CRC. Conclusion. TMEM100 is lowly expressed in CRC, which can suppress CRC cell growth by regulating the TGF-β signaling pathway.…”
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Granuloma Caused by Carbon Deposition in the Dermis by Rintaro Shibuya, Yuichiro Endo, Akihiro Fujisawa, Miki Tanioka, Yoshiki Miyachi

“…Previous case reports presented pencil core granuloma resembling malignant melanoma, haemangioma, or soft tissue sarcoma. …”
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Surgical Treatment of a Patient with a Solitary Thyroid Metastasis from Primary Sigmoid Adenocarcinoma: A Case Report and Literature Review by Kohei Yamahara, Toshiaki Moriki, Yuki Katsura, Kana Lee, Satoshi Ikegami

“…Malignant metastases to the thyroid are rare and even rarer from colorectal cancer (CRC). …”
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Diffuse Neurofibroma in a Patient with Unknown History of NF1 by Mahmoud A. K. Ebrahim, Mishal M. AlMutairi, Khaled M. Hindi, Jassem M. Bastaki

“…Malignant peripheral nerve sheath tumor (MPNST) is a rare disease in the parotid gland with a poor prognosis in most cases. …”
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Blocking Type I Interferon Production: A New Therapeutic Option to Reduce the HIV-1-Induced Immune Activation by Moritz Ries, Kathrin Pritschet, Barbara Schmidt

“…The promises of immune reconstitution and normal life expectancy, however, fall short for a number of patients, either through inadequate recovery of CD4+ T-cell counts or the occurrence of non-AIDS defining malignancies. In this respect, the prevalence of Epstein-Barr virus-associated Hodgkin lymphoma and human papillomavirus-related anal neoplasia is rising in aging HIV-1-infected individuals despite antiretroviral therapy. …”
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The Unexpected Diagnosis of Hepatic Tuberculosis in an Immunocompetent Patient by Nikolaos Garmpis, Christos Damaskos, Anna Garmpi, Aliki Liakea, Dimitrios Mantas

“…The differential diagnosis includes primary and metastatic liver malignancies. Our aim is to describe the rare entity of HTB via a case presentation. …”
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Plummer Vinson Syndrome: A Rare Syndrome in Male with Review of the Literature by Priyadarshini Karthikeyan, Nalini Aswath, Ramesh Kumaresan

“…As PVS is a precancerous condition with high malignant potential, early diagnosis is of utmost importance for better prognosis. …”
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Combination of Fluorescence-Guided Surgery With Photodynamic Therapy for the Treatment of Cancer by Jun He MD, Leping Yang MD, Wenjun Yi MD, Wentao Fan MD, Yu Wen MD, Xiongying Miao MD, Li Xiong MD

“…Fluorescence-guided surgery (FGS) uses a fluorescence contrast agent for in vivo tumor imaging to detect and identify both malignant and normal tissues. There are several advantages and clinical benefits of FGS over other conventional medical imaging modalities, such as its safety, effectiveness, and suitability for real-time imaging in the operating room. …”
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Pulmonary Alveolar Proteinosis by Sandeep M Patel, Hiroshi Sekiguchi, Jordan P Reynolds, Michael J Krowka

“…Previous case studies have found that the acquired form can be secondary to various autoimmune, infectious, malignant and environmental etiologies. Recent advances in the understanding of the pathophysiology of PAP demonstrate that the idiopathic form is due to antigranulocyte macrophage-colony stimulating factor antibodies. …”
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Political economics in health and implications for neurosurgery diseases by Yi Han, Yutao Huang

“…This review will discuss the effects of political-economic factors on the prevalence and treatment of neurosurgical diseases, including stroke, traumatic brain injury (TBI), intracerebral hemorrhage (ICH), and brain malignant tumors. Furthermore, the current challenges and future directions will be discussed. …”
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