Using Mathematical Modeling as a Resource in Clinical Trials by Evans K. Afenya

“…These models predict that malignant cells in the marrow and peripheral blood exhibit the tendency to evolve toward population levels that enable them to replace normal cells in these compartments in the untreated case. …”
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Colorectal Polyposis and Immune-Based Therapies by Pearl Jacobson-Brown, Manuela G Neuman

“…The progression from precancerous (adenomatous) colon polyps to malignant colorectal cancer involves the complex actions of various cytokines on T cell proliferation, cell-cell adhesion, apoptosis and host immunity. …”
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Acral Melanoma: A Review of Its Pathogenesis, Progression, and Management by Soo Hyun Kim, Hensin Tsao

“…Acral melanoma is a distinct subtype of cutaneous malignant melanoma that uniquely occurs on ultraviolet (UV)-shielded, glabrous skin of the palms, soles, and nail beds. …”
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Advancements and Future Directions of Dual-Target Chimeric Antigen Receptor T-Cell Therapy in Preclinical and Clinical Studies by Chenyun Zhang, Haizhou Liu

“…In recent years, chimeric antigen receptor T-cell (CAR-T) therapy has made groundbreaking progress in the treatment of various cancer types, particularly hematological malignancies. In the meantime, various preclinical and clinical studies have extensively explored dual-target CAR-T therapies which can be designed to recognize two antigens simultaneously based on the immunophenotype of tumor cells. …”
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Safety of Cyclophosphamide Therapy in Autoimmune Rheumatic Diseases by Ramaswamy Subramanian, Himanshu Pathak, Vinod Ravindran

“…However, its use may be limited by the toxicities including its adverse effects on gonads in the childbearing age group, severe infections, hemorrhagic cystitis, and malignancies associated with prolonged usage. As a result, mycophenolate, azathioprine, and rituximab have gained popularity over CYC as an induction and maintenance agent in many AIRDs. …”
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NFIB-Mediated lncRNA PVT1 Aggravates Laryngeal Squamous Cell Carcinoma Progression via the miR-1301-3p/MBNL1 Axis by Tian Tang, Feng Zeng

“…Laryngeal squamous cell carcinoma (LSCC) is one of the most common malignant tumors of head and neck cancers. In the past decades, although the therapy strategies of LSCC have made considerable improvement, the terrible outcomes of LSCC still bring an enormous burden to the world health care system. …”
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Levamisole-Induced immune phenomenon and its various clinical manifestations in children: Two case reports along with review of literature by Anu Punnen Kocheril, T Sathish Kumar, Dharshini Sathishkumar

“…In literature, levamisole-induced immune manifestations were described mostly in association with its use in treatment of rheumatoid arthritis, malignancies, and recently, in relation to the use of illicit cocaine contaminated with levamisole among adults. …”
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Results of endoscopic treatment of early colorectal cancer by M. Yu. Agapov, N. A. Taran, O. G. Polushin, K. V. Stegny

“…At following accepted criteria (high or moderate grade of tumor differentiation, absence of malignant cells at the crust line, absence of vessel invasion, absence of secondary foci, submucosal invasion of no more than 1000 µm or 2-nd Haggit level) no local relapses or metastatic lesions after endoscopic tumor removal were detected.Conclusions. …”
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A Rare Case Report: Primary Vulvar Adenocarcinoma of Mammary Gland Type by Dai X, Lei H, Jie R

“…This case underscores the importance of specific markers like TRPS1 in accurately diagnosing rare vulvar malignancies and guiding effective treatment strategies. …”
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Efficacy and safety of dupilumab in a patient with metastatic clear cell renal cell carcinoma by César Ferreira, Egídio Freitas, Tiago Torres

“…In summary, although the initial findings are promising, comprehensive research is essential to ensure the optimal management of AD in patients with a history of malignancies.…”
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Unexpected cause of headache in a patient with Noonan syndrome: aseptic meningitis by Hacer Efnan Melek Arsoy, Öner Özdemir, Ümmügülsüm Dikici, Ece Tüsüz Önata, Recep Polat

“…Malignancies, autoimmune diseases, viral and fungal infections, as well as aseptic meningitis due to certain drugs are frequently seen. …”
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Application of cellular microstructural diffusion MRI (cell size imaging) in rectal lesions: a preliminary study by Peisi Kou, Liangjie Lin, Ying Li, Hui Qin, Kun Zhang, Wenhua Zhang, Juan Li, Yong Zhang, Jingliang Cheng

“…It could be helpful in differentiating malignant and benign lesions, distinguishing AC from MC, and in predicting the TB status.…”
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Anticancer effects of ABTL0812, a clinical stage drug inducer of autophagy-mediated cancer cell death, in glioblastoma models by Andrea Mancini, Alessandro Colapietro, Loredana Cristiano, Alessandra Rossetti, Vincenzo Mattei, Giovanni Luca Gravina, Giovanni Luca Gravina, Héctor Perez-Montoyo, Marc Yeste-Velasco, Jose Alfon, Carles Domenech, Claudio Festuccia

“…BackgroundGlioblastoma multiforme (GBM) is the most malignant adult brain tumor. Current standard of care treatments have very limited efficacy, being the patients´ overall survival 14 months and the 2-year survival rate less than 10%. …”
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The Prevalence of Dermoscopy Use Among Dermatology Residents in Riyadh, Saudi Arabia: Cross-Sectional Study by Abdullah Almeziny, Rahaf Almutairi, Amal Altamimi, Khloud Alshehri, Latifah Almehaideb, Asem Shadid, Mohammed Al Mashali

“…Dermoscopy is an evidence-based practice used to enhance the early detection of skin malignancies and to help distinguish between various skin conditions, including pigmented and nonpigmented skin malignancies. …”
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Role of Positron Emission Tomography-Computed Tomography Scan in Reaching Definite Diagnosis in Patients With Fever of Unknown Origin and Inflammation of Unknown Origin in Rheumato... by Koreli UY, Torun ES, Adaş M

“…PET/CT’s high sensitivity implies that negative results can reliably exclude malignancies in most cases. However, due to its low specificity, positive test may not always imply a serious underlying condition. …”
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Cancer mortality trends after implementation of the national programme for dispensarization of certain groups of the adult population: a population-based study from arkhangelsk, no... by L. E. Valkova, M. L. Levit, V. M. Merabishvili, A. Yu. Pankrateva, M. V. Krupina, D. M. Dubovichenko, A. V. Agaeva, A. Yu. Ryzhov, E. F. Potekhina, M. Yu. Valkov

“…Anonymous data about patients with malignant neoplasms of the colon, rectum, lung, breast, cervix, uterus, ovaries, prostate gland, kidney undergoing examination (screening) at the first stage of the DCGAP from 2006 to 2019 were extracted from the ARCR database. …”
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Black posterior vitreous detachment: A 10-year historical cohort of pigmented uveal tumors by Vicktoria Vishnevskia-Dai, Hila Goldberg, Michael Ostrovsky, Ofira Zloto, Rachel Shemesh

“…Conclusion: A pigmentary form of PVD may accompany both benign and malignant pigmented uveal tumors, affecting a wide range of patients. …”
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CYFIP2: potential pancreatic cancer biomarker and immunotherapeutic target by Cong Xiao, Xiaojuan Zhang, Bobo Hou, Ping Wan, Zhenjun Cao, Xuefeng Rao

“…Abstract Objective It has been shown that the CYFIP2 (Cytoplasmic FMR1-interacting protein 2) gene is apoptosis p53-dependent and is associated with poor prognosis in malignant tumors such as gastric cancer and other and cervical cancer. …”
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Identification of Potential Biomarkers and Metabolic Changes in the Serum of Breast Lump Patients Among Kelantanese Based on 1H NMR Metabolomics by Ahmad Zulkefly, Wan Norlina Wan Azman, Julia Omar, Nurul Syakima Ab Mutalib, Desy Fitrya Syamsumir, M Maulidiani, Faridah Abas, Maya Mazuwin Yahya, Muhamad Syahmi Yamin, Wan Faiziah Wan Abdul Rahman, Tengku Ahmad Damitri Al-Astani Tengku Din

“…Serum samples from healthy controls, benign breast lump patients, and malignant breast lump patients were analyzed using proton nuclear magnetic resonance spectroscopy (1H NMR). …”
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Metastatic Renal Cell Carcinoma Presenting as Gastric Ulcer: Case Report and Literature Review by Alhareth Al Juboori, Satinder Kaur, Atigadda Reddy

“…Renal cell carcinoma (RCC) accounts for approximately 3% of all adult malignancies. True gastrointestinal metastases, specifically to gastric wall, have been rarely observed. …”
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