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3201
Role of Epstein-Barr Virus and Human Papilloma Virus in the Development of Oropharyngeal Cancer: A Literature Review
Published 2022-01-01“…It was found that, among the carcinogenic mechanisms of HPV, E6 and E7 proteins are responsible for the malignization process, inhibiting tumor suppressors p53 and pRb. …”
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3202
Anti-tumor role and molecular mechanism of vanillic acid
Published 2025-01-01“…Abstract Vanillic Acid (VA) is an aromatic acid extracted from traditional Chinese medicine such as Angelica sinensis and Panax ginseng, which has demonstrated potent anti-cancer activity, inhibiting the onset and progression of various malignant tumors. This review highlights the principal mechanism by which VA exerts its anticancer activity, including apoptosis induction, specifically promoting the generation of intracellular reactive oxygen species (ROS), which in turn triggers mitochondrial apoptosis. …”
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3203
Invasion of glioma cells through confined space requires membrane tension regulation and mechano-electrical coupling via Plexin-B2
Published 2025-01-01“…Abstract Glioblastoma (GBM) is a malignant brain tumor with diffuse infiltration. Here, we demonstrate how GBM cells usurp guidance receptor Plexin-B2 for confined migration through restricted space. …”
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3204
Unusual Length of Pedicle: Pedunculated Squamous Papilloma of Uvula Causing Unusual Dysphagia of Long Duration in a Child of 10 Years
Published 2014-01-01“…Benign oropharyngeal tumors are far less common compared to malignant tumors. Oropharyngeal papilloma is present in adults. …”
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3205
Demanding Diagnosis of Splenic Angiosarcoma as Cause of Delayed Treatment of Spontaneous Splenic Rupture: A Case Report and Literature Review
Published 2017-01-01“…Primary splenic angiosarcoma is a very rare mesenchymal malignant tumor associated with a poor prognosis due to its high metastatic potential. …”
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3206
Malakoplakia of the Pancreas with Simultaneous Colon Involvement: Case Report and Review of the Literature
Published 2015-01-01“…More studies are necessary to determine the probability of malignancies arising in association with malakoplakia, in order to devise appropriate treatment protocols.…”
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3207
Chondrosarcoma Arising from the Posterior Iliac Crest Extending into the Spinal Canal
Published 2021-01-01“…Chondrosarcoma is a malignant tumor characterized by the production of a cartilage matrix. …”
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3208
Tumoral Prostate Shows Different Expression Pattern of Somatostatin Receptor 2 (SSTR2) and Phosphotyrosine Phosphatase SHP-1 (PTPN6) According to Tumor Progression
Published 2009-01-01“…Also, SSTR2 is expressed in stromal cells. In malignant prostate tissue, SHP-1 was diminished in 28/45 cases or absent in 12/45 cases, whereas SSTR2 epithelial was diminished in 38/45 cases or lost in only 2/45 cases. …”
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3209
Concurrent Cemento-Osseous Dysplasia and Osteogenic Sarcoma: Report of Two Cases
Published 2012-01-01“…Cemento-osseous dysplasia (COD) represents a rare group of benign fibroosseous disorders, while osteogenic sarcoma (OS) on the hand, is a malignant tumour of ominous prognosis. A combination of COD and OS is rare and sparsely reported in literature. …”
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3210
Treatment of Bleeding Diathesis Associated with a Heparin-Like Anticoagulant in Plasma Cell Neoplasia Using Protamine
Published 2018-01-01“…With further investigation, this strategy could be applicable in other hematological malignancies with bleeding diathesis, chiefly if the pathophysiology of the HLAC is precisely defined.…”
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3211
Recurrent Villous Adenoma with High-Grade Dysplasia Arising in a Urethral Diverticulum
Published 2009-01-01“…The lesion recurred at one year without evidence of malignant transformation. We also present a brief literature review of urothelial villous adenomas.…”
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3212
Changes in hormone receptor when breast cancer metastasizes to the colon: case report and literature review
Published 2025-01-01“…CT and colonoscopy results revealed a malignant tumor in the ascending colon, and the patient underwent surgery. …”
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3213
Drug-Induced Hypersensitivity Syndrome: A Clinical, Radiologic, and Histologic Mimic of Lymphoma
Published 2018-01-01“…The clinical history, imaging, and biopsy findings initially raised concern for a malignant process, with a differential diagnosis including classic Hodgkin’s lymphoma and T-cell lymphoma. …”
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3214
Antiapoptotic Molecule Survivin in Transplantation: Helpful or Harmful?
Published 2018-01-01“…However, survivin’s potential ability to induce malignancies makes some concerns about its use in clinic. …”
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3215
A Diagnostic Dilemma: Waldenström's Macroglobulinemia/Plasma Cell Leukemia
Published 2012-01-01“…Disease symptoms can be due to infiltration of bone marrow and other tissue sites by malignant lymphoplasmacytic cells or due to the effects of elevated serum IgM levels. …”
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3216
Giant Condyloma Acuminatum of Vulva in an HIV-Infected Woman
Published 2017-01-01“…The disease is usually locally aggressive and destructive with a potential for malignant transformation. The causative organism is human papilloma virus. …”
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3217
The Role of Beta HPV Types and HPV-Associated Inflammatory Processes in Cutaneous Squamous Cell Carcinoma
Published 2020-01-01“…Beta HPV types are components of the normal flora; however, under the influence of certain cofactors, the virus may trigger a malignant process. Dysregulation of the immune system (chronic inflammation and immunosuppression), environmental factors (ultraviolet radiation), and genetic factors are the most important cofactors involved in beta HPV-related carcinogenesis. …”
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3218
Aseptic Meningitis as an Immune-Related Adverse Event after Pembrolizumab
Published 2019-01-01“…The management of patients with advanced malignancies is challenging, although recent advances with immunotherapy have shown better outcomes. …”
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3219
Swine Acute Diarrhea Syndrome Coronavirus: An Overview of Virus Structure and Virus–Host Interactions
Published 2025-01-01“…SADS-CoV, a recently identified <i>Rhinolophus</i> bat coronavirus HKU2-associated swine coronavirus, is a malignant pathogen that causes acute diarrhea, severe diarrhea, and weight loss in infected piglets. …”
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3220
MENINGIOMAS IN DOGS: EPIDEMIOLOGY, ADVANCEMENTS IN DIAGNOSTIC IMAGING AND THERAPEUTIC OPTIONS
Published 2025-01-01“…However, challenges persist in managing tumor recurrence and malignant forms, highlighting a need for further research into genetic markers and new therapeutic approaches. …”
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