Basal Cell Carcinoma Masked in Rhinophyma by Daniele De Seta, Francesca Yoshie Russo, Elio De Seta, Roberto Filipo

“…Rhinophyma can lead to a significant facial disfigurement and severe emotional distress, but it is not only an aesthetic problem, since rare cases of simultaneous presence of malignant tissue are described in the literature. The case of an 84-year-old farmer affected by basal cell carcinoma (BCC) and diagnosed in the context of rhinophyma is presented. …”
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Bromodomain-Containing Protein 4: A Dynamic Regulator of Breast Cancer Metastasis through Modulation of the Extracellular Matrix by Jude Alsarraj, Kent W. Hunter

“…Metastasis is an extremely complex process that accounts for most cancer-related deaths. Malignant primary tumors can be removed surgically, but the cells that migrate, invade, and proliferate at distant organs are often the cells that prove most difficult to target therapeutically. …”
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PROTAC-based therapeutics for targeting HPV oncoproteins in head and neck cancers by Nobendu Mukerjee, Dattatreya Mukherjee

“…This targeted approach not only potentially reduces the side effects associated with conventional treatments but also directly interrupts the cancer-promoting activities of these proteins, offering a promising avenue for more effective and less invasive treatment of HPV-associated malignancies.…”
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Hemophagocytic lymphohistiocytosis secondary to refractory acute myeloid leukemia resolved after second line treatment with azacitidine plus venetoclax by Claudio Fozza

“…Secondary HLH typically occurs in conjunction with severe infections, malignancies or autoimmune disorders and intensive chemotherapy, potentially complicating treatment of acute myeloid leukemia (AML) in around 10% of cases. …”
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ERYTHROCYTE SEDEMENTATION RATE:A USEFUL TOOL IN DIAGNOSTIC APPROACH by Muhammad Usman

“…Although it doesn’t enjoy the status of being called a diagnostic test,even then it is in continuous use as a good indicator in conditions like infections and inflammations; for screening and prognosis of certain diseases and also for monitoring the course of an existing disease.It is a good indicator to estimate the quantitative change in plasma that may occur in a lot of clinical conditions ranging from simple to much serious disorders such as inflammation, infection, pregnancy, obesity and even malignancies. In certain hematological conditions such as polycythaemia, sickle cell anaemia, leukemia, hypoproteinaemia as well as few other conditions like hyper viscosity, congestive heart failure etc. …”
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Ossifying Fibroma of Mandible - A Case Report by Gargi Jadaun, A. Bhagwandas Rai, Saeeda Kharodia, Viral Gadhiya

“…Owing to multiplicity of features, tendency of recurrence, and possibility of malignant transformation, the diagnosis, treatment, and post-operative management of ossifying fibroma are always a challenge. …”
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THE GENUS AS, A POTENTIAL SOURCE OF ANTICANCER AGENT: AN UPDATED REVIEW

“…As a consequence, cancer  treatment is a global priority. A cell may acquire malignant characteristics by learning how to avoid  apoptosis. …”
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Historical management of equine resources in France from the Iron Age to the Modern Period: a cross disciplinary approach by Pierre Clavel, Jean Dumoncel, Clio Der Sarkissian, Andaine Seguin-Orlando, Laure Calvière-Tonasso, Stephanie Schiavinato, Lorelei Chauvey, Aude Perdereau, Jean-Marc Aury, Patrick Wincker, Vedat Onar, Benoît Clavel, Sébastien Lepetz, José Braga, Xuexue Liu, Antoine Fages, Naveed Khan, Oscar Estrada, Duha Alioglu, Charleen Gaunitz, Maude Barme, Pierre Bodu, Monique Olive, Olivier Bignon-Lau, Jean-Christophe Castel, Myriam Boudadi-Maligne, Nicolas Boulbes, Alice Bourgois, Franck Decanter, Sylvain Foucras, Stéphane Frère, Armelle Gardeisen, Gaëtan Jouanin, Charlotte Méla, Nicolas Morand, Ariadna Nieto Espinet, Olivier Putelat, Julie Rivière, Opale Robin, Marilyne Salin, Silvia Valenzuela-Lamas, Christian Vallet, Jean-Hervé Yvinec, Ludovic Orlando

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Zosteriform cutaneous metastases: A rare occurrence in ductal carcinoma breast after mastectomy by Roshany Sakthibalan, Trishna Vaishali Muthurathinam, Roshni Menon

“…This case highlights the importance of considering CM in a patient with lesions of zosteriform distribution, as early diagnosis aids in preventing the delay in treatment of underlying malignancies.…”
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Paraneoplastic syndrome with intestinal pseudo-obstruction in a patient with small cell lung carcinoma: a case report and literature review by Xiao-Jun Ren, Zhao-Hong Shi, Ying-Xia Cheng, Yun Luo

“…Paraneoplastic chronic intestinal pseudo-obstruction (CIPO) is a rare manifestation associated with small cell lung carcinoma and other malignancies. In this report, we present a challenging case involving a 60-year-old man with small cell lung carcinoma who developed symptoms of intestinal pseudo-obstruction, including abdominal distention, pain, and obstipation. …”
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Two Cases of Miliary Tuberculosis and Increasing Level of CA-125 by M Alimagham, S Aminiafshar, SMM H Moghaddam, S Shokuhi

“…Two cases of miliary tuberculosis and elevated levels of cancer antigen 125 Ovarian carcinoma is one of the most dangerous malignancies in women. The serum level of cancer antigen (CA) 125, as a tumour marker, is useful in the diagnosis of ovarian cancer. …”
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Current Endoscopic and Surgical Management of Pancreatic Cystic Lesions: A Comprehensive Review by Kunzah A. Syed, Elham Afghani, Kelly J. Lafaro

“…For these significant lesions, accurate characterization of cyst type and prediction of the risk of malignant progression are crucial for specific management, such as deciding to monitor a lesion or pursue surgical intervention. …”
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Radical Surgery of Only the Anterior Elements of the Spine at the Posterior Element Fusion Level due to Metastatic Thyroid Cancer by Ryuto Tsuchiya, Kazuki Fujimoto, Kazuhide Inage, Sumihisa Orita, Yasuhiro Shiga, Hiroto Kamoda, Kazuyo Yamauchi, Miyako Suzuki, Jun Sato, Koki Abe, Hirohito Kanamoto, Masahiro Inoue, Hideyuki Kinoshita, Masaki Norimoto, Tomotaka Umimura, Masao Koda, Takeo Furuya, Junichi Nakamura, Kazuhisa Takahashi, Seiji Ohtori

“…Similar situations may occur in cases involving other malignant tumor metastases or spinal primary tumors. …”
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Identification of Two Novel Immune Subtypes Characterized by Distinct Prognosis and Tumor Microenvironment in Osteosarcoma by Shunhan Yao, Meiling Deng, Xiaojing Du, Qingfeng Chen, Rongzhi Huang

“…Osteosarcoma is a kind of primary malignant tumor of bone. In recent years, its therapeutic effect and prognostic survival are dissatisfactory. …”
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Smooth Muscle Tumor Originating in the Pleura: A Case Report and Updated Literature Review by Santiago Fabián Moscoso Martínez, Vadim Zarubin, Geethapriya Rajasekaran Rathnakumar, Alireza Zarineh

“…She underwent an interventional radiology guided percutaneous core biopsy of the lesion, which disclosed a “Smooth Muscle Tumor of Undetermined Malignant Potential (SMT-UMP).” A video-assisted thoracoscopic surgery (VATS) was performed for diagnosis and treatment purposes. …”
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Neutrophils in Cancer: Two Sides of the Same Coin by Eileen Uribe-Querol, Carlos Rosales

“…Tumor-associated neutrophils (TANs) have relevant roles in malignant disease. Indeed neutrophils may be potent antitumor effector cells. …”
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Multifocal Osteonecrosis Secondary to Chronic Alcohol Ingestion by Kazu Matsumoto, Hiroyasu Ogawa, Haruhiko Akiyama

“…Multifocal osteonecrosis is caused by the several conditions including corticosteroid treatment, coagulation disorders, connective tissue disorders including systemic lupus erythematosus (SLE), inflammatory bowel disease, renal transplantation, and underlying malignancies. Alcohol abuse is one of the risk factors for osteonecrosis, and alcohol-induced osteonecrosis is 5% among all the osteonecrosis. …”
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Rare Benign Large Lymphoid Colonic Polyp by Yousef Alshamali, Ahmad Al Taleb, Talal Al-Taweel

“…Benign lymphoid polyp is a rare condition posing a diagnostic challenge as it can be misinterpreted as a malignant lesion.…”
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To Live or to Die: Prosurvival Activity of PPARγ in Cancers by Y. Lynn Wang, Qi Miao

“…We discuss the following five aspects of the nuclear hormone receptor and its agonists: (1) relative expression of PPARγ in human tumor versus normal tissues; (2) receptor-dependent proneoplastic effects; (3) impact of PPARγ and its agonists on tumors in animal models; (4) clinical trials of thiazolidinediones (TZDs) in human malignancies; (5) TZDs as chemopreventive agents in epidemiology studies. …”
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Nephron-Sparing Surgery for Adenocarcinoma in a Renal Allograft by Fernando Vázquez Alonso, Enrique Cardozo Rodríguez, Ignacio Puche Sanz, Jose Francisco Flores Martin, Jose Miguel Molina Hernandez, Raquel Berrio Campos, Javier Vicente Prados, Antonio Medina Benitez, Jose Manuel Cózar Olmo

“…The incidence of malignant tumors in recipients of renal allografts is higher than in the general population. …”
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