Vitamin D Receptor, Retinoid X Receptor, Ki-67, Survivin, and Ezrin Expression in Canine Osteosarcoma by John Davies, Heather Heeb, Rama Garimella, Kimberly Templeton, David Pinson, Ossama Tawfik

“…Canine osteosarcoma (OS) is an aggressive malignant bone tumor. Prognosis is primarily determined by clinical parameters. …”
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Cancer-associated fibroblasts promote pro-tumor functions of neutrophils in pancreatic cancer via IL-8: potential suppression by pirfenidone by Tomohiko Yagi, Shunsuke Kagawa, Shohei Nogi, Atsuki Taniguchi, Masashi Yoshimoto, Kanto Suemori, Yasuo Nagai, Shuto Fujita, Shinji Kuroda, Satoru Kikuchi, Yoshihiko Kakiuchi, Fuminori Teraishi, Kosei Takagi, Toshiaki Ohara, Hiroshi Tazawa, Toshiyoshi Fujiwara

“…PFD suppresses IL-8 secretion from CAF-stimulated neutrophils and mitigates the malignant traits of pancreatic cancer cells. Conclusion CAFs activate neutrophils and enhance the malignant phenotype of pancreatic cancer. …”
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Computer-tomography features of hemodynamics in hepatocellular carcinoma foci depend on the stage of histological differentiation by U. N. Tumanova, N. I. Yashina, Ye. A. Dubova, G. G. Karmazanovsky, A. I. Schegolev

“…Computer tomography scores should be applied as additional criteria of the tumor malignant potential and for estimation of treatment efficacy as well.…”
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Progress of research on management of skin graft-versus-host disease following allogeneic hematopoietic stem cell transplantation (异基因造血干细胞移植皮肤急性移植物抗宿主病管理的研究进展)... by FU Yuxin (符玉欣), ZHOU Ting (周婷)

“…Hematopoietic stem cell transplantation (HSCT) is an important method for the treatment of malignant and non-malignant refractory hematologic diseases. …”
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Risk Factors for Breast Cancer in the Female Population by Yoenny Peña García, Maikel Maceo González, Diamela Ávila Céspedes, Licet Utria Velázquez, Yohandra Más López

“…<strong>Introduction:</strong> breast cancer is the excessive growth of malignant cells in the breast tissue. In Cuba, this condition is the first cause of incidence and mortality among female sex malignant neoplasms. …”
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Giant Protruding Nodular Fasciitis of the Anterior Chest Wall Clinically Mimicking a Soft Tissue Sarcoma by Hideyuki Kinoshita, Tsukasa Yonemoto, Hiroto Kamoda, Yoko Hagiwara, Toshinori Tsukanishi, Sumihisa Orita, Kazuhide Inage, Naoya Hirosawa, Seiji Ohtori, Takeshi Ishii

“…The tumor appeared clinically malignant as it was protruding and had doubled in size within a few weeks, reaching approximately 8×6 cm. …”
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Evolution of drug therapy in patients with resectable gastric and esophageal‑gastric junction cancer by M. V. Sedova, M. A. Batov, V. S. Tretyak, A. A. Kolomeytseva, V. M. Khomyakov, N. N. Volchenko, A. A. Fedenko, A. D. Kaprin

“…Gastric cancer (GC) is the fifth most common malignant neoplasm in the world among all malignant tumors. …”
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Evaluation of Pathology Results of Patients with a History of Breast Cancer who were Operated on for Gynecological Pathologies or Prophylaxis by Necim Yalcin, Isin Ureyen, Aysun Alci, Mustafa Gokkaya, Alper Kahraman, Gorker Sel, Gulsum Ekin Sari, Tayfun Toptaş

“…The pathology revealed malignant/premalignant disease in seven (12.2%) patients. …”
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NOP2/Sun RNA Methyltransferase 4 Regulates the Mammalian Target of Rapamycin Signaling Pathway to Promote Hepatocellular Carcinoma Progression by Congren Wang, Shaoying Ke, Shaoze Lin, Conglin Lin, Zhibing Cai, Lingju Hong, Qunxiong Pan

“…The influence that NSUN4 exerted on HCC malignant progression could be reduced by the inhibitor of the mTOR pathway. …”
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AMPK: An energy sensor for non-small cell lung cancer progression and treatment by Zhi-Ting Zhong, Xu-Yan Wang, Ying Pan, Ke Zhou, Jing-Hui Chen, Yu-Qi Gao, Bo Dai, Zhi-Ling Zhou, Rui-Qi Wang

“…AMP-activated protein kinase (AMPK) is a key regulator of energy balance and homeostasis, and its dysregulation is a common feature in various malignancies, particularly in NSCLC with mutations in Liver kinase B1 (LKB1). …”
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Targeting BCMA in multiple myeloma: designs, challenges, and future directions by Yi Hu, Yuetao Xie, Xiaodong Wang, Lufeng Yang, He Geng, Zugang Yi, Yao Zhang, Lin Ma, Fang Chen

“…Abstract Chimeric antigen receptor (CAR) T cell therapy has emerged as a groundbreaking immunotherapy, demonstrating significant efficacy in treating B cell malignancies. In the context of multiple myeloma (MM), B cell maturation antigen (BCMA) has been identified as a critical target, driving the development of CAR T cell therapies designed to address this plasma cell cancer. …”
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Thioredoxin 1 in Prostate Tissue Is Associated with Gleason Score, Erythrocyte Antioxidant Enzyme Activity, and Dietary Antioxidants by Terrence M. Vance, Gissou Azabdaftari, Elena A. Pop, Sang Gil Lee, L. Joseph Su, Elizabeth T. H. Fontham, Jeannette T. Bensen, Susan E. Steck, Lenore Arab, James L. Mohler, Ming-Hui Chen, Sung I. Koo, Ock K. Chun

“…Greater Gleason score of malignant tissue corresponds to a greater difference in Trx 1 levels between malignant and benign tissue (P=0.04). …”
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T Cell Histiocyte Rich Large B Cell Lymphoma Presenting as Hemophagocytic Lymphohistiocytosis: An Uncommon Presentation of a Rare Disease by Uroosa Ibrahim, Gwenalyn Garcia, Amina Saqib, Shafinaz Hussein, Qun Dai

“…T cell histiocyte rich large B cell lymphoma (THRLBCL) is a rare subtype of non-Hodgkin’s lymphoma characterized by malignant B cells with reactive T lymphocytes. The pathophysiology is thought to involve cytokine-mediated evasion of T cell immune response by malignant B cells. …”
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New Insights in the Pathogenesis of HPV Infection and the Associated Carcinogenic Processes: The Role of Chronic Inflammation and Oxidative Stress by Simona Roxana Georgescu, Cristina Iulia Mitran, Madalina Irina Mitran, Constantin Caruntu, Maria Isabela Sarbu, Clara Matei, Ilinca Nicolae, Sandra Milena Tocut, Mircea Ioan Popa, Mircea Tampa

“…To this date, over 150 genotypes are known and are classified into two major groups, low-risk and high-risk strains, depending on the ability of the virus to induce malignant transformation. The host’s immunity plays a central role in the course of the infection; therefore, it may not be clinically manifest or may produce various benign or malignant lesions. …”
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Intermediate between Idiopathic Hypereosinophilia and Chronic Eosinophilic Leukemia: A Report of Two Hypereosinophilic Cases with Possible Novel Molecular Mutations by Jui Choudhuri, Mohammad Eskandari, Yang Shi, Yanhua Wang

“…To distinguish a reactive eosinophilia from its malignant counterpart is challenging. Establishing clonality of the eosinophils is crucial and considered the determining factor for establishing a diagnosis. …”
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Helicobacter pylori reduces METTL14-mediated VAMP3 m6A modification and promotes the development of gastric cancer by regulating LC3C-mediated c-Met recycling by Xixi Cui, Mingjie Chang, Yuqiong Wang, Jiayi Liu, Zenghui Sun, Qiyu Sun, Yundong Sun, Juchao Ren, Wenjuan Li

“…Abstract Helicobacter pylori (H. pylori) plays an important role in the malignant transformation of the gastric mucosa from chronic inflammation to cancer. …”
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Bernese Periacetabular Osteotomy in a Hip Extra-Articular Resection Followed by Reconstruction Using an Extracorporeal Irradiated Acetabulum Autograft with Megaprosthesis, for Prox... by Victor Barro, Roberto Velez, Daniel Pacha, Jordi Giralt, Isabel Roca, Marius Aguirre

“…Osteosarcoma is the most common primary malignant tumour of bone. The oncologic surgery of a proximal femur osteosarcoma affecting the hip joint can be very challenging. …”
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Eribulin Provides a Remarkable Effect in Trabectedin-Resistant Myxoid Liposarcoma by Hironari Tamiya, Hideaki Sabe, Katsunari Yamashita, Yoshinori Imura, Toru Wakamatsu, Satoshi Takenaka

“…Adriamycin-based chemotherapy is commonly used for malignant soft tissue sarcoma including myxoid liposarcoma. …”
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Mendelian randomization analysis reveals genetic evidence for a causal link between inflammatory bowel disease and uterine cervical neoplasms by Chunge Cao, Xiaorui Sun, Xiaohu Chen, Ying Zhang, Chaoyan Yue

“…The inverse-variance weighted (IVW) method was employed as primary analysis approach.ResultsIBD (IVW odds ratio = 1.127, 95% confidence interval = 1.016–1.251; p = 0.024) and CD (IVW odds ratio = 1.119, 95% confidence interval = 1.023–1.224; p = 0.014) exhibited a significant causal effect on malignant cervical carcinoma. Sensitivity analyses confirmed these findings.ConclusionGenetically predicted IBD and CD are risk factors for the development of malignant cervical carcinoma. …”
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DNA Methyltransferase Inhibition Promotes Th1 Polarization in Human CD4+CD25high FOXP3+ Regulatory T Cells but Does Not Affect Their Suppressive Capacity by Sija Landman, Marjan Cruijsen, Paulo C. M. Urbano, Gerwin Huls, Piet E. J. van Erp, Esther van Rijssen, Irma Joosten, Hans J. P. M. Koenen

“…In vivo studies in patients with hematological malignancies that were treated with 5-azacytidine (Vidaza) supported the in vitro findings. …”
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