Mitohormesis : la clé de voûte de la résistance thérapeutique des cellules cancéreuses by Boët, Emeline, Saland, Estelle, Skuli, Sarah, Griessinger, Emmanuel, Sarry, Jean-Emmanuel

“…A large body of literature highlights the importance of energy metabolism in the response of haematological malignancies to therapy. In this review, we are particularly interested in acute myeloid leukaemia, where mitochondrial metabolism plays a key role in response and resistance to treatment. …”
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Sarcomatoid renal pelvis carcinoma: A case report by Xuechao Zhang, Yanan Jin, Weiran Zhang, Yawei Zhang, Haifeng Wang

“…Sarcomatoid carcinoma is a malignant tumor of epithelial origin, some of the cells of which are differentiated in a sarcomatoid direction and are highly invasive. …”
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Pseudomyxoma Peritonei in a Case of Carcinoma Cervix: Subtle Finding With Implications on Management and Prognosis by Sarita Kumari, Suvidya Singh

“…It has important implications on prognosis depending on whether seen in conjunction with a benign or a malignant tumor. In the current report, we describe a case of PMP in a case of advanced endocervical adenocarcinoma of the cervix which was managed surgically.…”
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Hydatid Cyst of the Rib: A New Case and Review of the Literature by A. Chafik, A. Benjelloun, A. El Khadir, R. El Barni, A. Achour, M. A. Ait Benasser

“…The disease often takes the appearance of abscess or malignant lesion. We report a case of a 35-year-old man with a hydatid cyst of the rib complicated with cutaneous fistula. …”
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Bilateral Paget’s Disease of the Breast—Case Report of Long-Time Misdiagnosed Tumors with Underlying Ductal Carcinomas and Review of the Literature by Dietrich Barth

“…We report on a 72-year old patient with a history of 2.5 years without any malignant findings, followed by the identification of a bilateral Paget’s disease with bilateral breast cancers. …”
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VSL#3 Probiotic Upregulates Intestinal Mucosal Alkaline Sphingomyelinase and Reduces Inflammation by Isaac Soo, Karen L Madsen, Qassim Tejpar, Beate C Sydora, Richard Sherbaniuk, Benedetta Cinque, Luisa Di Marzio, Maria Grazia Cifone, Claudio Desimone, Richard N Fedorak

“…Reduced levels of alkaline sphingomyelinase have been found in premalignant and malignant intestinal epithelia and in ulcerative colitis tissue. …”
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Stage IV Small Lymphocytic Lymphoma Presenting with Unilateral Vision Loss by Christopher Le, Adam Jacob, Devarajan Iyengar, John Dedousis, Antonios Tsompanidis

“…Small lymphocytic lymphoma (SLL) is a manifestation of chronic lymphocytic leukemia (CLL) in which malignant B-cell lymphocytes accumulate in the lymph nodes or bone marrow. …”
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Askin's Tumor: A Dual Case Study by Bikash Shrestha, Bhupendra Nath Kapur, Kavita Karmacharya, Sunita Kakkar, Ranjit Ghuliani

“…It is a subset of Ewing sarcoma characterized histologically by the presence of small round blue cells. It is a highly malignant tumor with guarded prognosis, which is dependent upon the extension of tumor at the time of diagnosis. …”
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Two Case Reports of Benign Testicular Mesothelioma and Review of the Literature by Cristobal Ramirez Sevilla, Carme Admella Salvador, Josep Feliu Canaleta, Juan Llopis Manzanera, Miguel Angel Barranco Sanz, Juan Antoni Romero Martin, Sergi Bernal Salguero

“…At the testicles the mesothelioma had been reported first in 1957 like a malignant non-germ-cells tumor. The objective is to present two case reports of benign testicular mesothelioma and review of the literature.…”
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Toll-like receptor 2-mediated ERK activation significantly upregulates interleukin-6 expression in M2-polarized macrophages by Jo Wol Soon, Kim Sung Dae, Jeong Soo Kyung, Oh Su Jung, Baik Ji Sue, Seo Ji An, Baek Jeong-Hwa, Lee Chang Geun, Kang Young-Rok, Jeong Min Ho, Park Moon-Taek

“…M2-polarized macrophages and interleukin (IL)-6 significantly alter the tumor microenvironment and promote the malignant behaviors of tumor cells. This study aimed to establish M2-type macrophages from THP-1 cells, which are human leukemia monocytes, and investigate the significance of toll-like receptor 2 (TLR2) signaling in IL-6 production.…”
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Elevated Carbohydrate Antigen 19-9 in Patients with True (Epithelial) Splenic Cysts – Rare or Undiscovered? by Michal Soudack, Alon Ben-Nun, Chaim Toledano

“…However, its limitation is its nonspecificity, because elevated levels may be encountered in other gastrointestinal disorders, both benign and malignant. The following case is a patient with a true (epithelial) splenic cyst with elevated serum levels of carbohydrate antigen 19-9.…”
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Biliary Adenofibroma: A Rare Liver Tumor with Transition to Invasive Carcinoma by Ayham Alshbib, Krzysztof Grzyb, Trygve Syversveen, Henrik Mikael Reims, Kristoffer Lassen, Sheraz Yaqub

“…Biliary adenofibroma is a rare benign liver tumor with potential for malignant transition. It has a bile duct origin characterized by a complex tubulocystic biliary epithelium with fibrous stroma. …”
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Beyond gluten-free diet: a critical perspective on phase 2 trials on non-dietary pharmacological therapies for coeliac disease by Davide Scalvini, Chiara Scarcella, Giulia Mantica, Erica Bartolotta, Stiliano Maimaris, Erica Fazzino, Federico Biagi, Federico Biagi, Annalisa Schiepatti, Annalisa Schiepatti

“…Moreover, a tiny minority of coeliac patients can develop pre-malignant/malignant complications of coeliac disease, a group of conditions, that despite being rare, are still burdened by a poor prognosis due to the lack of effective therapies. …”
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Increased aPKC Expression Correlates with Prostatic Adenocarcinoma Gleason Score and Tumor Stage in the Japanese Population by Anthony S. Perry, Bungo Furusato, Raymond B. Nagle, Sourav Ghosh

“…Increased aPKC staining was observed in malignant prostate cancer, in comparison to benign tissue. …”
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Concurrent squamous cell carcinoma and warthin tumor - A rare encounter by Sakshi Deorah, Shivanjali Raghuvanshi, Sharon John, Krachi Agarwal, Shalini Gupta

“…Oral cancer ranks sixth most common malignant neoplasm worldwide, with Squamous Cell Carcinoma being the predominant type observed in the head and neck region. …”
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Unusual Case of Anaplastic Large Cell Lymphoma Presenting as a Breast Mass in a Patient with no History of Breast Implants by Yana Ivashkevich, Yaroslav Chernov, Denis Chinenov, Evgeniy Shpot, Alexander A. Bessonov, Arthy Yoga, Kirill A. Lyapichev, Sergej Konoplev

“…Adenocarcinoma is the most common malignant neoplasm involving breast tissue. In contrast to carcinomas, the other types of malignant neoplasms involving the breast are relatively uncommon. …”
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PPAR Agonists for the Prevention and Treatment of Lung Cancer by Sowmya P. Lakshmi, Aravind T. Reddy, Asoka Banno, Raju C. Reddy

“…Lung cancer is the most common and most fatal of all malignancies worldwide. Furthermore, with more than half of all lung cancer patients presenting with distant metastases at the time of initial diagnosis, the overall prognosis for the disease is poor. …”
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Collection and Transplantation of Peripheral Blood Stem Cells in Children: A Single-Center Experience by Cengiz Zeybek, Orhan Gürsel, Ahmet Bolat, İbrahim Eker, Erman Atas, Ahmet Emin Kürekçi

“… Background/Aims: As a source of hematopoietic stem cells, peripheral blood stem cells have been used more frequently in both malignant and non-malignant diseases. There are some difficulties in the collection of PBSC from children compared to adults such as vascular access and, extracorporeal circuit volume, especially in small children.Methods: In this study, we present our experience in 63 children who underwent peripheral blood stem cell collection and transplantation between November 2016 and September 2023. …”
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Prognostic Factors for Cancer-Specific Survival and Disease-Free Interval of Dogs with Mammary Carcinomas by Elaine da Silva Soares, Fabrício Luciani Valente, Carolina Camargos Rocha, Carlos Eduardo Real Pereira, Thaís Barroso Sarandy, Fabiano Luiz Dulce de Oliveira, Sabrina Loise de Morais Calado, Andréa Pacheco Batista Borges

“…To contribute to the understanding of the biological behavior of this neoplasm, 385 cases were analyzed, 89% malignant, 4% benign, and 7% non-neoplastic lesions. …”
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Proteogenomic analysis reveals Arp 2/3 complex as a common molecular mechanism in high risk pancreatic cysts and pancreatic cancer by A. K. M. Firoj Mahmud, Dina Gamaleldin Mansour Aly, Yelin Zhao, Mikael Benson, Martin Smelik, Oleg Sysoev, Hui Wang, Xinxiu Li

“…These findings suggest that the Arp2/3 complex-associated genes can serve as potential biomarkers for predicting the malignant transformation of pancreatic cysts, opening new avenues for targeted therapies and early detection strategies.…”
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