Semiautomatic Algorithm for Lymph Node Analysis Corrected for Partial Volume Effects in Combined Positron Emission Tomography-Computed Tomography by Ralph A. Bundschuh, Markus Essler, Julia Dinges, Christian Berchtenbreiter, Jan Mariss, Axel Martínez-Möller, Gaspar Delso, Melanie Hohberg, Stephan G. Nekolla, Dominik Schulz, Sibylle I. Ziegler, Markus Schwaiger

“…If SUV 2.5 was used as a threshold value to distinguish between benign and malignant lesions, 11 of the 47 lesions changed from benign to malignant after the PVC. …”
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Personalized neuron-specific enolase level based on EEG pattern for prediction of poor outcome after cardiac arrest by Juliette Pelle, Estelle Pruvost-Robieux, Florence Dumas, Antonin Ginguay, Julien Charpentier, Clara Vigneron, Frédéric Pène, Jean Paul Mira, Alain Cariou, Sarah Benghanem

“…Benign EEG was associated with lower level of NSE compared to malignant and highly malignant patterns (p < 0.001). …”
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Appendiceal cancer in pregnancy and circulating tumor cells detection in the umbilical cord by Risa Kudo, Kensuke Matsumoto, Tatsuya Ishiguro, Tomoyuki Sekizuka, Koji Nishijima, Takayuki Enomoto, Kosuke Yoshihara

“…Although malignant tumors metastasizing to infant or the placenta are occasionally reported during pregnancy, the adverse effects of maternal malignant tumors on fetus have not been clarified. …”
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A novel gene signature for predicting outcome in colorectal cancer patients based on tumor cell-endothelial cell interaction via single-cell sequencing and machine learning by Lina Pang, Qingxia Sun, Wenyue Wang, Mingjie Song, Ying Wu, Xin Shi, Xiaonan Shi

“…Background: The intricate interactions between malignant cells and endothelial cells (ECs) are crucial in the progress of colorectal cancer (CRC). …”
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Protocol for assessing immune-target cell interactions using a single-cell cytotoxicity assay by Zhihao Wei, Konglan Lin, Min Huang, Shicheng Su, Yiwen Lu

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Leiomyomatosis Peritonealis Disseminata with Sarcomatous Transformation: A Rare Case Report and Literature Review by Song Xu, Jing Qian

“…Increasingly, literature supports that LPD is an iatrogenic condition. Malignant transformation of LPD is rarely reported. …”
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A Rare Case of Immunotactoid Glomerulopathy Associated with Hodgkin Lymphoma by Keiki Nagaharu, Yuka Sugimoto, Keiki Kawakami

“…In hematologic malignancies, multiple myeloma and other mature B-cell malignancies are the most common hematologic malignancies, and Hodgkin lymphoma (HL) is extremely rare. …”
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Emerging Role of PET in the Diagnosis and Staging of Lung Cancer by Geoffery Coates, Stephen J Skehan

“…FDG PET has much higher accuracy than other imaging modalities for the differentiation of benign and malignant lung nodules. The sensitivity of PET is 96% and the specificity 77% for diagnosing malignant nodules. …”
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Significance of Glutathione Peroxidase 1 and Caudal-Related Homeodomain Transcription Factor in Human Gastric Adenocarcinoma by Jing Jing Han, De Rong Xie, Li Li Wang, Ye Qing Liu, Gong Fa Wu, Qing Sun, Yan Xian Chen, Ying Wei, Zhi Quan Huang, Hai Gang Li

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A Case of Unsuspected Peritoneal Mesothelioma Occurring with Colonic Adenocarcinoma Masquerading as Peritoneal Metastases by Wei Xie, Linda K. Green, Rishi A. Patel, Syeling Lai

“…We report a case of synchronous primary colonic adenocarcinoma and malignant mesothelioma. A 61-year-old male presented with a six-month history of fatigue and weight loss. …”
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Acute Lymphoblastic Leukemia Arising in CALR Mutated Essential Thrombocythemia by Stephen E. Langabeer, Karl Haslam, David O’Brien, Johanna Kelly, Claire Andrews, Ciara Ryan, Richard Flavin, Patrick J. Hayden, Christopher L. Bacon

“…The development of acute lymphoblastic leukemia in an existing myeloproliferative neoplasm is rare with historical cases unable to differentiate between concomitant malignancies or leukemic transformation. Molecular studies of coexisting JAK2 V617F-positive myeloproliferative neoplasms and mature B cell malignancies indicate distinct disease entities arising in myeloid and lymphoid committed hematopoietic progenitor cells, respectively. …”
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STAT signaling in the pathogenesis and therapy of acute myeloid leukemia and myelodysplastic syndromes by Zoe King, Sudhamsh Reddy Desai, David A. Frank, Aditi Shastri

“…Acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS) represent complex hematopoietic malignancies characterized by ineffective hematopoiesis and dysregulated myeloid differentiation. …”
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Anticytotoxic T-Lymphocyte Antigen-4 Induced Autoimmune Hypophysitis: A Case Report and Literature Review by Deborah Majchel, Mary T. Korytkowski

“…This impacts not only malignant cells but also different host organ-systems. …”
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In Vitro Screening and Transfection Concentration Optimization of Cynomolgus Monkey IκBα-siRNA by Zhaoxing Ou, Rui Zeng, Yifan Lin, Si Zhang, Mohammad Alzogool, Peng Zeng, Yuqing Lan

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Bilateral Primary Angiosarcoma of the Breast by P. Keshav, Shruti S. Hegde

“…Primary breast sarcomas are very rare entities, accounting for 0.04% of all malignant neoplasms. Angiosarcoma of breast is infrequent and is an endothelial malignant tumor with bad prognosis because of the frequency of metastasis and recurrence. …”
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Aggressive Behaviour of Metastatic Melanoma in a Patient with Neurofibromatosis Type 1 by Robert W. Foley, Robert M. Maweni, Aurelie Fabre, David G. Healy

“…Malignant melanoma is a common skin neoplasm bearing poor prognosis when presenting with metastases. …”
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A Case of Inverted Papilloma Originating from the Middle Ear and Review of the Literature by Eray Bayindir, Fatih Mehmet Hanege, Mahmut Tayyar Kalcioglu, Tulay Zenginkinet, Serdal Celik

“…Inverted papilloma (IP) with malignant transformation is rarely seen in the middle ear. …”
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Epidemiological Patterns of Skin Disease in Saudi Arabia: A Systematic Review and Meta-Analysis by Mohammad Almohideb

“…Basal cell carcinoma and squamous cell carcinoma were the most common malignant neoplasm in Saudi Arabia (51.4% and 22.5% of the malignant neoplasm, respectively), while malignant melanoma represents only 3.8% of the malignant skin cancer. …”
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Case Study of a Parotid Gland Adenocarcinoma Dedifferentiated from Epithelial-Myoepithelial Carcinoma by Salih Aydın, Umit Taskin, Kadir Ozdamar, Kadir Yücebas, Mehmet Sar, Mehmet Faruk Oktay, Ümit Seza Tetikkurt

“…Dedifferentiation is defined as high-grade malignant tumor development out of a low-grade malignant tumor. …”
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Usefulness of Whole-Body Fluorine-18-Fluorodeoxyglucose Positron Emission Tomography in Patients with Neurofibromatosis Type 1: A Systematic Review by Giorgio Treglia, Silvia Taralli, Francesco Bertagna, Marco Salsano, Barbara Muoio, Pierluigi Novellis, Maria Letizia Vita, Fabio Maggi, Alessandro Giordano

“…FDG-PET and PET/CT are useful methods to identify malignant change in neurogenic tumors in NF1 and to discriminate malignant from benign neurogenic lesions.…”
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