Chronic Lymphoid Leukemia Complicated with Ascites by Chemir Mamode, Patrice Beauregard, Serge Langevin, Charles-Jacques Mongeau

“…Ascites are common in malignancies of the gastrointestinal tract but are rarely associated with chronic lymphoid leukemia. …”
Get full text

A synchronous occurrence of breast cancer and pleural mesothelioma: a case report by Zaheer Ahmad, Hashir Jehanzeb, Saad Noor Hussain, M. Umar, Humna Saleem

“…Abstract Background Malignant mesotheliomas are aggressive forms of tumors arising from mesothelial cells. …”
Get full text

A study of the histopathological spectrum of thyroid neoplasms in a tertiary health care center by Rabia Parveen Siddiqui, Vanita Bhaskar, Kavita Swami, Varsha Pandey, Anubhav Chandrakar, Kasturi Mangrulkar

“…Background: Thyroid gland lesions are common and can result from systemic conditions such as Graves’ disease or localized abnormalities like nodular enlargement or tumors. Thyroid malignancies are the most prevalent endocrine cancers, accounting for approximately 92% of all endocrine malignancies. …”
Get full text

The CHK1 inhibitor prexasertib in BRCA wild-type platinum-resistant recurrent high-grade serous ovarian carcinoma: a phase 2 trial by Elena Giudice, Tzu-Ting Huang, Jayakumar R. Nair, Grant Zurcher, Ann McCoy, Darryl Nousome, Marc R. Radke, Elizabeth M. Swisher, Stanley Lipkowitz, Kristen Ibanez, Duncan Donohue, Tyler Malys, Min-Jung Lee, Bernadette Redd, Elliot Levy, Shraddha Rastogi, Nahoko Sato, Jane B. Trepel, Jung-Min Lee

Get full text

Coexisting Papillary and Clear Renal Cell Carcinoma in the Same Kidney by Murat Ustuner, Busra Yaprak, Kerem Teke, Seyfettin Ciftci, Mucahit Kart, Kursat Yildiz, Melih Culha

“…Bilateral synchronous benign and malignant renal tumors have been defined in some reports. …”
Get full text

Shedding New Light on Cutaneous Horns: A Comprehensive Review and Pitfall of Management by Leo Wan, Aileen Park, Kamran Arastu, Amor Khachemoune

“…Although the cause and pathogenesis of these lesions were long misunderstood, cutaneous horns are now generally recognised to be reactive skin growths that can result from a variety of infectious, malignant, pre-malignant, and benign conditions. Most cutaneous horns are benign, but approximately 16%–20% are malignant, with squamous cell carcinoma being the most common malignant underlying aetiology. …”
Get full text

Analysis of a mouse germ cell tumor model establishes pluripotency-associated miRNAs as conserved serum biomarkers for germ cell cancer detection by Amanda R. Loehr, Dennis M. Timmerman, Michelle Liu, Ad J. M. Gillis, Melia Matthews, Jordana C. Bloom, Peter K. Nicholls, David C. Page, Andrew D. Miller, Leendert H. J. Looijenga, Robert S. Weiss

“…Abstract Malignant testicular germ cells tumors (TGCTs) are the most common solid cancers in young men. …”
Get full text

Solid Indeterminate Nodules with a Radiological Stability Suggesting Benignity: A Texture Analysis of Computed Tomography Images Based on the Kurtosis and Skewness of the Nodule Vo... by Bruno Max Borguezan, Agnaldo José Lopes, Eduardo Haruo Saito, Claudio Higa, Aristófanes Corrêa Silva, Rodolfo Acatauassú Nunes

“…A total of 100 chest CT scans were evaluated, including 50 cases of SINRSBs and 50 cases of malignant nodules. SINRSB CT scans were performed using the same noncontrast enhanced CT protocol and equipment; the malignant nodule data were acquired from several databases. …”
Get full text

Depletion of myeloid-derived suppressor cells sensitizes murine multiple myeloma to PD-1 checkpoint inhibitors by Qiang Wang, Qing Yi, Wei Xiong, Rui Duan, Jianfei Qian, Liuling Xiao, Miao Xian, Pan Su, Chuanchao Zhang, Yabo Li, Ling Zhong, Chengyun Zheng

Get full text

Metastatic Melanoma Presenting as Intussusception in an 80-Year-Old Man: A Case Report by Sarah Alghamdi, Yumna Omarzai

“…Malignant melanoma of the gastrointestinal tract is an uncommon neoplasm that could be primary or metastatic. …”
Get full text

Solitary Fibrous Tumor of the Sigmoid Colon Masquerading as an Adnexal Neoplasm by Laura Bratton, Rabih Salloum, Wenqing Cao, Aaron R. Huber

“…Although all solitary fibrous tumors have the potential to recur or metastasize, those with malignant histologic features tend to behave more aggressively. …”
Get full text

An Intratumoral Aneurysm and an Extrarenal Synchronous Cystic Tumour in a Case of a Renal Cell Carcinoma by Supun De Silva, Lalani De Silva, Susantha De Silva, Priyani Amarathunga

“…Although few cases were reported with various vascular anomalies associated with a renal tumor, this is the first ever case to find an arteriovenous fistula with a secondary venous aneurysm located inside a malignant renal mass. Similarly, no solid RCC is reported to present with an extrarenal malignant cystic nodule. …”
Get full text

Primary multiple synchronous tumors: soft tissue sarcoma of the retroperitoneal space and metastatic prostate cancer by O. A. Mailyan, K. Yu. Kanukoev, P. G. Berezin, K. M. Nyushko, V. A. Gorbach

“…Soft tissue sarcomas are rare malignant tumors that develop in the connective tissues and remain poorly understood due to the fact that they make up less than 1% of all malignant diseases. …”
Get full text

Mismatch repair deficiency and microsatellite instability in urothelial carcinoma: a systematic review and meta-analysis by Ninet Sinaii, Guru Sonpavde, Amin H Nassar, Min Yuen Teo, Andrea B Apolo, Jonathan E Rosenberg, Giovanni Maria Iannantuono, Elias B A Chandran, Saad O Atiq, Dilara Akbulut, Nicholas I Simon, Abdul Rouf Banday, Salah Boudjadi, Sandeep Gurram, Gisela Butera, Jonathan A Coleman

Get full text

Single-cell transcriptomes of dissecting the intra-tumoral heterogeneity of breast cancer microenvironment by Peixian Chen, Kaifeng Liang, Xiaofan Mao, Qiuyuan Wu, Zhiyan Chen, Yabin Jin, Kairong Lin, Tiancheng He, Shuqing Yang, Huiqi Huang, Guolin Ye, Juntao Gao, Dan Zhou, Zhihao Zeng

“…Methods The composition of breast cancer based on the single-cell transcriptomes of 54,055 high-quality cells from clinical specimens of 4 malignant and 4 non-malignant patients were investigated. …”
Get full text

Small Renal Masses: Incidental Diagnosis, Clinical Symptoms, and Prognostic Factors by F. M. Sánchez-Martín, F. Millán-Rodríguez, G. Urdaneta-Pignalosa, J. Rubio-Briones, H. Villavicencio-Mavrich

“…Clear cell carcinoma is the most frequent cellular type of malign SRM. Conclusions. Only some SRMs are benign. …”
Get full text

Colposcopy: its importance for the prevention of cervical cancer by Dayamí Rodríguez Soto, Eneida Bravo Polanco

“…Cervical cancer, or carcinoma of the cervix, is a disease that has caused great impact in all social spheres, contributing to the high rates of morbidity and mortality throughout the world, including malignant neoplasms that develop in the lower fibromuscular portion of the uterus. …”
Get full text

Rare Cause for Sudden Right Heart Failure by Amir M. Nia, Natig Gassanov, Matthias Schmidt, Ferdinand Kuhn-Régnier, Erland Erdmann, Fikret Er

“…Right heart failure occurs daily in clinical settings, but an underlying cardiac malignant tumor is very uncommon. We report a case of a 48-year-old man presenting only with palpitations and decompensated heart failure. …”
Get full text

Modernization of cancer services in Moscow, the main challenges and possible solutions by A. P. Gnatyuk

“…Malignant neoplasms are taking second place in the structure of mortality and continue to be a major public health problem, both in the Russian Federation and in Moscow. …”
Get full text

Pharmacological activity of OST-01, a natural product from baccharis coridifolia, on breast cancer cells by HyunJun Kang, Dinh Hoa Hoang, Melissa Valerio, Khyatiben Pathak, William Graff, Alexis LeVee, Jun Wu, Mark A. LaBarge, David Frankhouser, Russell C. Rockne, Patrick Pirrotte, Bin Zhang, Joanne Mortimer, Le Xuan Truong Nguyen, Guido Marcucci

Get full text