The Diagnostic Value of Brush Cytology Alone and in Combination with Tumor Markers in Pancreaticobiliary Strictures by Ufuk Barış Kuzu, Bülent Ödemiş, Nesrin Turhan, Erkan Parlak, Selçuk Dişibeyaz, Nuretdin Suna, Erkin Öztaş, Muhammet Yener Akpınar, Adem Aksoy, Serkan Torun, Hakan Yıldız, Ertuğrul Kayaçetin

“…Aim. Differentiation of malignant and benign strictures constitutes a problem despite the increasing experience of the endoscopists, radiologists, and pathologists. …”
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The role of immunotherapy in the treatment of lip squamous cell carcinoma: A series of six cases and a review of the current literature by Ido Amir, Nir Tsur, Itamar Averbuch, Gideon Bachar, Noga Kurman

“…Another had a PET-avid supraclavicular node negative for malignancy. The median follow-up time since treatment initiation was 11.49 months (IQR 7.77 - 29.03). …”
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Comparison on the Efficacy between Partially Covered Self-Expandable Metal Stent with Funnel-Shaped Enlarged Head versus Uncovered Self-Expandable Metal Stent for Palliation of Gas... by Jung Wan Choe, Jong Jin Hyun, Dong-won Lee, Sang Jun Suh, Seung Young Kim, Sung Woo Jung, Young Kul Jung, Ja Seol Koo, Hyung Joon Yim, Sang Woo Lee

“…Patients with inoperable or advanced malignancy were included. Technical feasibility and clinical outcomes were compared. …”
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Boanmycin overcomes bortezomib resistance by inducing DNA damage and endoplasmic reticulum functional impairment in multiple myeloma by Jin-Xing Wang, Ling Zhang, Peng-Wei Zhang, Luo-Wei Yuan, Jian Jiang, Xiao-Hui Cheng, Wei Zhu, Yong Lei, Fa-Qing Tian

“…Abstract Background Multiple myeloma (MM) is a hematological malignancy characterized by uncontrolled proliferation of plasma cells and is currently incurable. …”
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Primary Neuroendocrine Carcinoma of Ocular Adnexa by Daisuke Yamanouchi, Toshiyuki Oshitari, Yosuke Nakamura, Jiro Yotsukura, Kaoru Asanagi, Takayuki Baba, Tomohiro Nizawa, Takashi Kishimoto, Yoko Yonemori, Satoshi Ota, Shuichi Yamamoto

“…Although primary NEC of the ocular adnexa is extremely rare, the tumor has high malignancy and readily metastasizes. Thus, combined therapy including surgery, radiotherapy, and/or chemotherapy is needed for complete management of NEC.…”
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Bladder-sparing therapy in a case report of huge muscle-invasive bladder IMT treated with 1470 nm diode laser en bloc resection followed by laparoscopic partial cystectomy by Junhao Chu, Huisheng Yuan, Zhihui Zhang, Jiajun Kan, Shishuai Duan, Zilong Wang, Zilong Wang, Zilong Wang, Muwen Wang

“…BackgroundBladder inflammatory myofibroblastic tumor (IMT) is a rare intermediate malignancy. Muscle-invasive bladder IMT is associated with a high risk of recurrence and metastasis, and bladder-sparing treatments for this condition are still under exploration. …”
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Exploring the heterogeneity of HER2 gene status and expression in non-positive breast cancer patients: insights from immunohistochemistry and fluorescence in situ hybridization by Jingmin Zhong, Beibei Gao, Qingjie Wang, Jun He, Danjv Luo, Chen Zhang, Jun Fan, Xiu Nie

“…Abstract Breast cancer became the most prevalent malignancy among women, and HER2 expression status is critical for treatment decisions. …”
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Exploring the anti-metastatic potential of sunitinib and novel analogs in colorectal cancer: insights into HIF-1α mediated metastasis by Fatemeh B. Rassouli, Maryam M. Matin, Maryam M. Matin, Farzin Hadizadeh, Farzin Hadizadeh, Masoud Nejabat, Hossein Allahverdizadeh, Hamidreza Jamali, Shahin Gharedaghi, Halimeh Hassanzadeh

“…IntroductionColorectal cancer (CRC) is a prevalent malignancy worldwide with high mortality rate. Metastasis, the primary cause of cancer-related deaths, is attributed to various factors including tumor hypoxia. …”
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Imaging Flow Cytometric Identification of Chromosomal Defects in Paediatric Acute Lymphoblastic Leukaemia by Ana P. A. Simpson, Carly E. George, Henry Y. L. Hui, Ravi Doddi, Rishi S. Kotecha, Kathy A. Fuller, Wendy N. Erber

“…Acute lymphoblastic leukaemia is the most common childhood malignancy that remains a leading cause of death in childhood. …”
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Comparing the Prognostic Value of Lactate to the Neutrophil to Lymphocyte Ratio Among Sepsis Patients: A Prospective Cohort Study by Bou Chebl R, Haidar S, Kattouf N, Assaf M, Alwan JS, Khamis MM, Abdeldaem K, Makki M, Tamim H, Abou Dagher G

“…No significant differences were found in AUCs between lactate and NLR in patients with septic shock, Lactate< 2, Lactate≥ 2, diabetes, malignancy, chronic kidney diseases, other sources of infection, albumin ≥ 30 and age ≥ 65.Conclusion: In this study, lactate but not NLR was associated with in-hospital mortality. …”
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Clinicopathological Analysis of 14 Cases of Primary Pulmonary Lymphoepithelial Carcinoma by Yixuan FANG, Anzhe WANG, Lumin SHEN, Xiao YUAN, Yu KONG

“…Background and objective Primary pulmonary lymphoepithelial carcinoma (PPLEC) is a rare form of lung malignancy, accounting for only 0.7% of all lung cancers. …”
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Mechanism of Action of Decitabine in the Treatment of Acute Myeloid Leukemia by Regulating LINC00599 by Fan Du, Ting Jin, Li Wang

“…Acute myeloid leukemia (AML) is a heterogeneous malignancy with a low long-term survival rate. The aim of this study was to investigate the effects of decitabine (DAC) treatment cell proliferation and apoptosis in AML and role of the expression of LINC00599 and, consequently, miR-135a-5p. …”
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Heterogeneity of cancer-associated fibroblast subpopulations in prostate cancer: Implications for prognosis and immunotherapy by Chen Ding, Jiange Wang, Jie Wang, Jiqiang Niu, Zhikai Xiahou, Zhou Sun, Zhenzhen Zhao, Dongyang Zeng

“…Background: Prostate cancer stands as the second most common malignancy among men, notorious for its intricate heterogeneity, especially evident in metastatic disease. …”
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MicroRNA-21 as a Regulator of Cancer Stem Cell Properties in Oral Cancer by Milica Jaksic Karisik, Milos Lazarevic, Dijana Mitic, Maja Milosevic Markovic, Nicole Riberti, Drago Jelovac, Jelena Milasin

“…Oral squamous cell carcinoma (OSCC) is a highly aggressive malignancy with poor prognosis, mainly due to the presence of cancer stem cells (CSCs), a small subpopulation of cells that contribute to therapy resistance and tumor progression. …”
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Clear Cell Carcinoma Arising from Cesarean Section Scar Endometriosis: Case Report and Review of the Literature by Sakura Ijichi, Taisuke Mori, Izumi Suganuma, Takuro Yamamoto, Hiroshi Matsushima, Fumitake Ito, Makoto Akiyama, Izumi Kusuki, Jo Kitawaki

“…The incidence of endometriosis affecting skin tissue represents only 0.5–1.0% of all endometriosis cases. A malignancy in the abdominal wall arising from endometriosis following cesarean section is even rarer; only 21 cases have previously been reported. …”
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miR-34a Regulates Multidrug Resistance via Positively Modulating OAZ2 Signaling in Colon Cancer Cells by Yong Li, Ping Gong, Ji-xue Hou, Wei Huang, Xiao-ping Ma, Yu-li Wang, Jing Li, Xiao-bin Cui, Na Li

“…Although aberrant expression of miR-34a, an essential tumor suppressor miRNA, has been frequently observed in colon cancer (CCa), whether miR-34a can regulate CCa progression by modulating other facets of this malignancy (such as multidrug resistance, MDR) remains unknown. …”
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Research on therapeutic clinical trials including immunotherapy in triple-negative breast cancer: a bibliometric analysis by Qi Xu, Xiaoyu Feng, Siyuan Qin, Yu Hong, Rui Cui, Jia Liang, Zhuya Xiao, Yuan Li

“…BackgroundBreast cancer, particularly triple-negative (TNBC), is a leading malignancy with aggressive traits and high metastasis rates. …”
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Impact of leukemia subtype and demographics on patient quality of life in 76 countries: a cross-sectional study by Sam Salek, Samantha Nier, Zack Pemberton-Whiteley, Tatyana Ionova, Giuseppe Ianni, Giovanni Tripepi, Nick York, Nicole Schroeter, Kathryn Huntley, Michael Rynne, Denis Costello, Lidija Pecova, Esther Natalie Oliva

“…BackgroundDisease-specific factors associated with decreased quality of life (QoL) in patients with leukemia have not been studied in a large-scale, global, observational study.MethodsThis cross-sectional study used the validated Hematological Malignancy Patient Reported Outcomes (HM-PRO) questionnaire to assess the impact of leukemia subtype, age, sex, and years living with the disease on QoL of patients with leukemia.ResultsOverall, 2,628 patients responded: 45.7% had chronic lymphocytic leukemia (CLL), 34.0% had chronic myeloid leukemia (CML), 11.8% had acute myeloid leukemia (AML), and 3.5% had acute lymphoblastic leukemia (ALL). …”
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Plasma Iron Levels at Early Breast Cancer Diagnosis Are Associated With Development of Secondary Metastases: A Single-Center Retrospective Cohort Study by Jasmine De Troy, Sarah-Maria Fendt, Sigrid Hatse, Patrick Neven, Ann Smeets, Annouschka Laenen, Hans Wildiers

“…Background: Breast cancer is the most common malignancy in women and the leading cause of cancer-related death. …”
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Surgical margins of the oral cavity: is 5 mm really necessary? by James Fowler, Yael Campanile, Andrew Warner, Francisco Laxague, Naif Fnais, Kevin Fung, Adrian Mendez, Danielle MacNeil, John Yoo, David Palma, Anthony Nichols

“…Abstract Background Squamous cell carcinoma is the most common malignancy of the oral cavity. Primary treatment involves surgical resection of the tumour with a surrounding margin. …”
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