Glucose metabolism impairment in major depressive disorder by Fanhao Meng, Jing Wang, Long Wang, Wei Zou

“…Major depressive disorder (MDD) is a common mental disorder with chronic tendencies that seriously affect regular work, life, and study. …”
Get full text

Randomization and placebo effects in clinical trials of major depressive disorder by James A. Rogers, Stephen Senn

Get full text

Study of Life Events and Quality of Life in Patients of Major Depressive Disorder by Alkesh Patil, Aparna Sengupta, Ashwini Mule, Sagar Karia

“…Objectives: The aim of this research was to study the relationship of major depressive disorder with quality of life and stressful life events in adults. …”
Get full text

Oxidative alterations in exfoliated oral mucosa cells of patients with major depressive disorder by Lukas Mendes de Abreu, Cintia Rodrigues da Silva, Ana Laura Ferreira Bortoleto, Giovana Barros Nunes, Matheus Martins Gracia, Rafael Akira Tzanno Murayama, Daniel Galera Bernabé, Gisele Zoccal Mingoti

Subjects: “…Major depressive disorder…”
Get full text

Treatments for partial remission of major depressive disorder: a systematic review and meta-analysis by Marlies E Brouwer, Gert J Geurtsen, Damiaan A J P Denys, Joost Gülpen, Eva A M van Dis, Claudi L Bockting

“…Question Partial remission of major depressive disorder (MDD) is a debilitating and distressing clinical state related to chronicity, morbidity and relapse. …”
Get full text

Classification of schizophrenia, bipolar disorder and major depressive disorder with comorbid traits and deep learning algorithms by Xiangning Chen, Yimei Lu, Joan Manuel Cue, Mira V. Han, Vishwajit L. Nimgaonkar, Daniel R. Weinberger, Shizhong Han, Zhongming Zhao, Jingchun Chen

“…In this study, we use polygenic risk scores (PRSs) of 42 traits comorbid with schizophrenia (SCZ), bipolar disorder (BIP), and major depressive disorder (MDD) to evaluate their utilities. …”
Get full text

Differentiation value of miR-26b for major depressive disorder, schizophrenia, generalized anxiety disorder by Lingming Kong, Xiaoli Zhu, Liyi Zhang, Shengdong Chen

“…Introduction: First episode and drug naive schizophrenia (SZ) patients comorbid with major depressive episode and generalized anxiety disorder (GAD) comorbid with major depressive disorder (MDD) are common in clinical practice, overlapping symptomatology during first presentation of MDD, SZ and GAD challenged the diagnostic process. …”
Get full text

Effect of vortioxetine versus venlafaxine on cognitive functions in adults with major depressive disorder: A randomized-controlled trial by Chayan K. Manna, Rajeev Ranjan, Pankaj Kumar, Shamshad Ahmad, Santanu Nath

Subjects: Get full text

Beneath the surface: unveiling the gut–brain axis in anorexia and depression by Fatima Shahid, Zain Afridi, Muhammad Ali, Muhammad Nabeel Saddique, Javed Iqbal, Anurag Jha

Subjects: Get full text

Using multiomic integration to improve blood biomarkers of major depressive disorder: a case-control studyResearch in context by Amazigh Mokhtari, El Chérif Ibrahim, Arnaud Gloaguen, Claire-Cécile Barrot, David Cohen, Margot Derouin, Hortense Vachon, Guillaume Charbonnier, Béatrice Loriod, Charles Decraene, Ipek Yalcin, Cynthia Marie-Claire, Bruno Etain, Raoul Belzeaux, Andrée Delahaye-Duriez, Pierre-Eric Lutz

“…Summary: Background: Major depressive disorder (MDD) is a leading cause of disability, with a twofold increase in prevalence in women compared to men. …”
Get full text

Individualized resting-state functional connectivity abnormalities unveil two major depressive disorder subtypes with contrasting abnormal patterns of abnormality by Keke Fang, Lianjie Niu, Baohong Wen, Liang Liu, Ya Tian, Huiting Yang, Ying Hou, Shaoqiang Han, Xianfu Sun, Wenzhou Zhang

“…Abstract Modern neuroimaging research has recognized that major depressive disorder (MDD) is a connectome disorder, characterized by altered functional connectivity across large-scale brain networks. …”
Get full text

Interactions between ABC gene polymorphisms and processing speed in predicting depression severity by Meijiang Jin, Lei Ji, Maojia Ran, Yan Bi, Hang Zhang, Yuanmei Tao, Hanmei Xu, Shoukang Zou, Hong Zhang, Tao Yu, Li Yin

Subjects: “…Major depressive disorder (MDD)…”
Get full text

Beneficial and harmful effects of duloxetine versus placebo, ‘active placebo’ or no intervention for adults with major depressive disorder: a systematic review with meta-analysis and trial sequential analysis of randomised clinical trials by Christian Gluud, Marija Barbateskovic, Joanna Moncrieff, Faiza Siddiqui, Janus C Jakobsen, Mathias Maagaard, Sophie Juul, Johanne Juul Petersen, Caroline Barkholt Kamp, Mark Abie Horowitz, Kiran Kumar Katakam

“…Objectives To assess the beneficial and harmful effects of duloxetine versus ‘active placebo’, placebo or no intervention for adults with major depressive disorder.Design Systematic review with meta-analysis and trial sequential analysis of randomised trials.Data sources Cochrane Central Register of Controlled Trials, MEDLINE, Embase, PsycINFO and other relevant databases up until January 2023. …”
Get full text

Dynamic Impact of the Sleep Disorder, Depression and Anxiety on the Cognitive Function in the First-Episode Depressive Patients by Zhang W, Zhou N, Li J

Subjects: “…major depressive disorder…”
Get full text

Understanding adolescent depression in Singapore: a qualitative study by Ngar Yee Poon, Cheryl Bee-Lock Loh

“…Methods: Semi-structured interviews were conducted with 14 adolescents, aged between 13 and 19 years, who were diagnosed and treated for diagnostic and statistical manual of mental disorders, 5th edition major depressive disorder and clinically judged to have recovered at the time of recruitment. …”
Get full text

EVALUATION OF THE THERAPEUTIC EFFECTS OF SALVIA ROSMARINUS ESSENTIAL OIL ON NERVOUS SYSTEM DISORDERS by Malina Mihaela Visternicu, Viorica Rarinca, Vasile Burlui, Alin Ciobica

“…This review explores the therapeutic potential of rosemary in alleviating nervous system disorders such as Alzheimer's disease (AD), major depressive disorder (MDD), epilepsy, Parkinson's disease (PD), addiction, and attention-deficit hyperactivity disorder (ADHD). …”
Get full text

Dhat Syndrome: Epidemiology, Risk Factors, Comorbidities, Diagnosis, Treatment, and Management by Yukino N. Strong, Angel Li, Michael E. White, Abrahim N. Razzak, Danyon J. Anderson, Alan D. Kaye, Edwin W. Herron, Nazih P. Khater, Elyse M. Cornett, Ivan Urits

“…Treatment for Dhat syndrome is the same as treatments for major depressive disorder.…”
Get full text

Prediction of individual patient outcomes to psychotherapy vs medication for major depression by Devon LoParo, Boadie W. Dunlop, Charles B. Nemeroff, Helen S. Mayberg, W. Edward Craighead

“…Abstract Treatments for major depressive disorder (MDD) include antidepressant medications and evidence-based psychotherapies, which are approximately equally efficacious. …”
Get full text

LSD and psilocybin for chronic nociplastic pain: A narrative review of the literature supporting the use of classic psychedelic agents in chronic pain by J Van Der Walt, R Parker

“…The new wave of research into psychedelics for major depressive disorder provides an opportunity to investigate and understand the potential for incorporating these drugs into chronic pain management pathways. …”
Get full text

Bupropion Mediated Effects on Depression, Attention Deficit Hyperactivity Disorder, and Smoking Cessation by Austin Clark, Brendan Tate, Bretton Urban, Ryan Schroeder, Sonja Gennuso, Shahab Ahmadzadeh, David McGregor, Brook Girma, Sahar Shekoohi, Alan D. Kaye

“…Our review demonstrates that bupropion is superior to placebo and non-inferior to SSRIs such as escitalopram in treating major depressive disorder. More research is needed to determine positive patient-centered outcomes such as increases in quality of life. …”
Get full text