-
4061
Investigating the impact of microbiome-changing interventions on food decision-making: MIFOOD study protocol
Published 2025-01-01“…Key inclusion criteria are 18–60 years of age and exclusion criteria are type 2 diabetes, psychiatric disease, and Magnetic Resonance Imaging (MRI) contraindications. …”
Get full text
Article -
4062
Treatment time and learning curve analysis of 1.5 T MR-Linac workflows led by radiation oncologists or therapists
Published 2025-03-01“…Adapt-to-Position, ATP) magnetic resonance guided radiotherapy (MRgRT) on a 1.5 Tesla MR-Linac. …”
Get full text
Article -
4063
Cardiovascular risk burden, dementia risk and brain structural imaging markers: a study from UK Biobank
Published 2024-02-01“…Background Cardiovascular risk burden is associated with dementia risk and neurodegeneration-related brain structure, while the role of genetics and incident cardiovascular disease (CVD) remains unclear.Aims To examine the association of overall cardiovascular risk burden with the risk of major dementia subtypes and volumes of related brain regions in a large sample, and to explore the role of genetics and CVD onset.Methods A prospective study among 354 654 participants free of CVD and dementia (2006–2010, mean age 56.4 years) was conducted within the UK Biobank, with brain magnetic resonance imaging (MRI) measurement available for 15 104 participants since 2014. …”
Get full text
Article -
4064
Age-related differences in long-term potentiation-like plasticity and short-latency afferent inhibition and their association with cognitive function
Published 2024-02-01“…Background The neurophysiological differences in cortical plasticity and cholinergic system function due to ageing and their correlation with cognitive function remain poorly understood.Aims To reveal the differences in long-term potentiation (LTP)-like plasticity and short-latency afferent inhibition (SAI) between older and younger individuals, alongside their correlation with cognitive function using transcranial magnetic stimulation (TMS).Methods The cross-sectional study involved 31 younger adults aged 18–30 and 46 older adults aged 60–80. …”
Get full text
Article -
4065
Determining the incidence, risk factors and biological drivers of irritable bowel syndrome (IBS) as part of the constellation of postacute sequelae of SARS-CoV-2 infection (PASC) o...
Published 2025-01-01“…Both samples will undergo a novel method to quantitate humoral and mucosal immune responses to host-derived faecal communities in conjunction with magnetic bead-based separation and high-depth shotgun microbial sequencing. …”
Get full text
Article -
4066
A New Transformation Method of the T<sub>2</sub> Spectrum Based on Ordered Clustering—A Case Study on the Pore-Throat Utilization Rule of Supercritical CO<sub>2</sub> Flooding in L...
Published 2025-01-01“…Nuclear magnetic resonance (NMR) and high-pressure mercury injection (HPMI) have been widely used as common characterization methods of pore-throat. …”
Get full text
Article -
4067
Altered medial temporal lobe subregion volumes in systemic lupus erythematosus patients with neuropsychiatric symptoms
Published 2025-01-01“…Abstract Background Systemic lupus erythematosus (SLE) often presents with neuropsychiatric (NP) involvement, including cognitive impairment and depression. Past magnetic resonance imaging (MRI) research in SLE patients showed smaller hippocampal volumes but did not investigate other medial temporal lobe (MTL) regions. …”
Get full text
Article -
4068
Predicting Axillary Lymph Node Metastasis in Young Onset Breast Cancer: A Clinical-Radiomics Nomogram Based on DCE-MRI
Published 2025-01-01“…Precisely forecasting axillary lymph node metastasis (ALNM) is essential for customizing treatment plans and enhancing patient results.Objective: This research sought to create and verify a clinical-radiomics nomogram that combines radiomic features from Dynamic Contrast-Enhanced Magnetic Resonance Imaging (DCE-MRI) with standard clinical predictors to improve the accuracy of predicting ALNM in young breast cancer patients.Methods: We performed a retrospective analysis at one facility, involving the creation and validation of a nomogram in two stages.At first, a medical model was developed utilizing conventional indicators like tumor dimensions, molecular classifications, multifocal presence, and MRI-determined ALN status.A more detailed clinical-radiomics model was subsequently developed by integrating radiomic characteristics derived from DCE-MRI images.These models were created using logistic regression analyses on a training dataset, and their effectiveness was assessed by measuring the area under the receiver operating characteristic curve (AUC) in a separate validation dataset.Results: The clinical-radiomics nomogram surpassed the clinical-only model, recording an AUC of 0.892 in the training dataset and 0.877 in the validation dataset.Significant predictors included MRI-reported ALN status and select radiomic features, which markedly enhanced the model’s predictive capacity.Conclusion: Integrating radiomic features with clinical predictors in a nomogram significantly improves ALNM prediction in young onset breast cancer, providing a valuable tool for personalized treatment planning. …”
Get full text
Article -
4069
Comparative study of arthroscopic autologous cancellous bone grafting and medial malleolar osteotomy combined with autologous periosteal iliac bone grafting for the treatment of os...
Published 2025-01-01“…Compared the surgical time of the two groups; the visual analog scale (VAS) scores, American Orthopaedic Foot & Ankle Society (AOFAS) scores, and ankle joint mobility were used preoperatively, and at 3 months and 1 year postoperatively to assess clinical efficacy; the magnetic resonance observation of cartilage repair tissue (MOCART) 2.0 ankle scores were evaluated at early postoperatively and 1 year postoperatively to assess cartilage repair. …”
Get full text
Article -
4070
Aspergillus fumigatus Influences Gasdermin-D-Dependent Pyroptosis of the Lung via Regulating Toll-Like Receptor 2-Mediated Regulatory T Cell Differentiation
Published 2021-01-01“…Flow cytometry was used to detect splenic CD4+CD25+FOXP3+ Tregs. Using magnetic beads to extract CD4+ T cells from mice spleen, the effects of A. fumigatus conidia or TLR2 inhibitor (C29) to differentiate CD4+ T cells in vitro were tested. …”
Get full text
Article -
4071
Anterior Controllable Antedisplacement and Fusion (ACAF) for Cervical Stenosis Patients With Hyperextension Injury: A Retrospective Study
Published 2025-02-01“…All patients underwent x‐ray, computed tomography (CT), and magnetic resonance imaging (MRI) before and after surgery. …”
Get full text
Article -
4072
Stimulation of DC-CIK with PADI4 Protein Can Significantly Elevate the Therapeutic Efficiency in Esophageal Cancer
Published 2019-01-01“…The tumor growth was measured with magnetic resonance imaging (MRI). Results. Following incubation with lysate from PADI4-overexpressing cells, the ratio of CD40+ DCs increased by 17.5%. …”
Get full text
Article -
4073
Myofibrillogenesis Regulator-1 in Smooth Muscle Cells Modulates Inflammation Signaling Pathways via Regulating ROCK1 Ubiquitination and Degradation to Impact Aortic Dissection
Published 2025-02-01“…Hang Yin,1– 5,* Xiaoxing Li,6,* Dazhou Lu,1– 5,* Xin Zhao,7,* Zeyu Yang,1– 5 Zerui Wang,1– 5 Feng Xu,1– 5 Yuguo Chen,1– 5 Chuanbao Li1– 5 1Department of Emergency Medicine, Qilu Hospital of Shandong University, Jinan, People’s Republic of China; 2Shandong Provincial Clinical Research Center for Emergency and Critical Care Medicine, Institute of Emergency and Critical Care Medicine of Shandong University, Chest Pain Center, Qilu Hospital of Shandong University, Jinan, People’s Republic of China; 3Key Laboratory of Emergency and Critical Care Medicine of Shandong Province, Key Laboratory of Cardiopulmonary-Cerebral Resuscitation Research of Shandong Province, Shandong Provincial Engineering Laboratory for Emergency and Critical Care Medicine, Qilu Hospital of Shandong University, Jinan, People’s Republic of China; 4Shandong Key Laboratory: Magnetic Field-Free Medicine & Functional Imaging (MF), Qilu Hospital of Shandong University, Jinan, People’s Republic of China; 5NMPA Key Laboratory for Clinical Research and Evaluation of Innovative Drug, Qilu Hospital of Shandong University, Jinan, People’s Republic of China; 6Department of Geriatrics, Qilu Hospital, Shandong University, Jinan, Shandong, People’s Republic of China; 7Department of Cardiovascular Surgery, Qilu Hospital of Shandong University, Jinan 250012, Shandong, People’s Republic of China*These authors contributed equally to this workCorrespondence: Chuanbao Li; Yuguo Chen, Department of Emergency Medicine, Qilu Hospital of Shandong University, Jinan, People’s Republic of China, Email bao2460@126.com; chen919085@sdu.edu.cnBackground: Aortic dissection (AD) is a life-threatening cardiovascular emergency and currently lacks effective drug treatment. …”
Get full text
Article -
4074
Evaluation of Metabolic Characteristics of Brain Tumours Utilising 31-Phosphorus MR Spectroscopy in 3T MRI: A Cross-sectional Study
Published 2025-01-01“…Introduction: The characterisation of brain tumours is predominantly based on Magnetic Resonance Imaging (MRI) for structural details and invasive histopathology for certainty. …”
Get full text
Article -
4075
PLL-g-HPA Hydrogel Loaded Human Umbilical Cord Mesenchymal Stem Cells Promote Burn Wound Healing in Rat Model by Regulating Inflammation Response
Published 2025-01-01“…Therefore, the aim of this study was to evaluate the therapeutic effect of hUC-MSCs combined with PLL-g-HPA hydrogel on full thickness burn injury in rat model.Methods: The PLL-g-HPA hydrogel was developed and characterized by Scanning Electron Microscopy (SEM), Fourier-Transform Infrared Spectroscopy (FTIR), Hydrogen-1 nuclear magnetic resonance (H-NMR). The cytotoxicity to human foreskin fibroblasts (HFF) were assessed by CCK-8 assay and live/dead quantification and antibacterial activity against Escherichia coli and Staphylococcus aureus was also detected by colony forming unit. …”
Get full text
Article -
4076
Efficacy of non-invasive brain stimulation interventions on cognitive impairment: an umbrella review of meta-analyses of randomized controlled trials
Published 2025-02-01“…Repetitive transcranial magnetic stimulation (rTMS) significantly enhanced short-term global cognition (standardized mean difference [SMD], 0.44; 95% CI 0.02–0.86), language (SMD, 1.64; 95% CI 1.22–2.06), executive function (SMD, 1.64; 95% CI 0.18–0.83), and long-term global cognition (SMD, 0.29; 95% CI 0.07–0.50). …”
Get full text
Article -
4077
Can ChatGPT4-vision identify radiologic progression of multiple sclerosis on brain MRI?
Published 2025-01-01“…We aimed to compare the performance of GPT4V to pretrained U-Net and vision transformer (ViT) models for the identification of the progression of multiple sclerosis (MS) on magnetic resonance imaging (MRI). Methods Paired coregistered MR images with and without progression were provided as input to ChatGPT4V in a zero-shot experiment to identify radiologic progression. …”
Get full text
Article -
4078
Radiogenomics and machine learning predict oncogenic signaling pathways in glioblastoma
Published 2025-01-01“…Advanced imaging techniques, particularly magnetic resonance imaging (MRI), are crucial in assessing GBM. …”
Get full text
Article -
4079
End-to-End Stroke Imaging Analysis Using Effective Connectivity and Interpretable Artificial Intelligence
Published 2025-01-01“…The goal of this pipeline is to define an efficient brain representation for connectivity in stroke data derived from magnetic resonance imaging. Ultimately, this representation is used within a directed graph convolutional architecture and investigated with explainable artificial intelligence (AI) tools, offering a more detailed understanding of how stroke alters communication within the brain. …”
Get full text
Article -
4080
Phytochemical and Bioactivity Evaluation of Bee Pollen and Androecia of <i>Castanea</i>, <i>Salix</i>, and <i>Quercus</i> Species
Published 2024-12-01“…<i>N</i><sup>1</sup>,<i>N</i><sup>5</sup>,<i>N</i><sup>10</sup>-tricaffeoylspermidine was isolated, and its structure was elucidated by nuclear magnetic resonance (NMR) and high-resolution mass spectrometry (HRMS). …”
Get full text
Article