The plasma metabolome of juvenile idiopathic arthritis varies according to subtype and underlying inflammatory status by Jooa Kwon, Melanie R. Neeland, Justine A. Ellis, Jane Munro, Richard Saffery, Boris Novakovic, Toby Mansell

“…Methods Targeted nuclear magnetic resonance (NMR) metabolomic profiles of plasma of 72 children with JIA and 18 controls were assessed cross-sectionally. …”
Get full text

Modulation of Acupuncture at Quchi (LI 11) and Waiguan (SJ 5) acupoints on LTP-like Plasticity by Qianqian SUN, Guo YU, Huitian ZHANG, Xiaokuo HE

“…Motor evoked potential (MEP) amplitudes induced by transcranial magnetic stimulation (TMS) over the bilateral M1 were measured throughout the whole treatment process, including before acupuncture (15 min), the needle in situ (30 min) and the needle removal (20 min), the unilateral acupuncture effect on LTP-like plasticity induced by PAS was explored. …”
Get full text

Enriched rehabilitation on brain functional connectivity in patients with post-stroke cognitive impairment by Yaping Huai, Weiwei Yang, Yichen Lv, Kui Wang, Hongyu Zhou, Yiqing Lu, Xiaoyun Zhang, Yaze Wang, Jibing Wang, Xin Wang

“…We investigated the altered resting-state functional connectivity (RSFC) with the right dorsolateral prefrontal cortex (DLPFC) in patients with PSCI following ER training through functional magnetic resonance imaging (fMRI). Additionally, twenty people undergoing routine physical examinations in the outpatient department of our hospital were selected as the healthy control (HC) group.ResultsBefore training, both groups of PSCI patients exhibited significant impairment in overall cognitive function, attention function, and executive function compared to the HC group. …”
Get full text

Thermal Performance Analysis of Nanofluids for Heat Dissipation Based on Fluent by Junqiang Xu, Zemin Shang, Shan Qing

“…Among them, CuO-H₂O demonstrates excellent heat transfer performance due to its high thermal conductivity, Fe₃O₄-H₂O offers potential for further optimization by combining thermal and magnetic properties, and Al₂O₃-H₂O exhibits strong chemical stability, making it suitable for a wide range of applications. …”
Get full text

Towards quantitative reconstruction of past monsoon precipitation based on tetraether membrane lipids in Chinese loess by J. Guo, J. Guo, M. Ziegler, L. Fuchs, Y. Sun, F. Peterse

“…Furthermore, the DC records show that precipitation amount on the CLP varies at both the precession scale and the obliquity scale, as opposed to the primarily precession-scale variations in speleothem <span class="inline-formula"><i>δ</i>¹⁸</span>O and <span class="inline-formula"><i>δ</i>²</span>H<span class="inline-formula">_wax</span> at Yuanbao and the 100 kyr cycle in other loess proxies, such as magnetic susceptibility, which rather indicates the relative intensity of the EAM. …”
Get full text

Dynamic selectout and voting-based federated learning for enhanced medical image analysis by Saeed Iqbal, Adnan N Qureshi, Musaed Alhussein, Khursheed Aurangzeb, Atif Mahmood, Saaidal Razalli Bin Azzuhri

“…We assess our approach on a dataset of medical images, including magnetic resonance imaging scans, and find that the FL model performs noticeably better (F1 Score = 0.968, Sensitivity = 0.977, Specificity = 0.945, and AUC = 0.950). …”
Get full text

Effect of straw retention and mineral fertilization on P speciation and P-transformation microorganisms in water- extractable colloids of a Vertisol by S. Bai, S. Bai, Y. Ge, D. Yao, Y. Wang, J. Tan, J. Tan, S. Zhang, Y. Peng, X. Jiang

“…Here, a fixed field experiment (<span class="inline-formula">∼</span> 13 years) in a Vertisol was performed to explore the impacts of straw retention and mineral fertilization on inorganic P, organic P, and P-transformation microorganisms in bulk soils and WECs through a sequential extraction procedure, P K-edge X-ray absorption near-edge structure (XANES), <span class="inline-formula">³¹</span>P nuclear magnetic resonance (NMR), and metagenomics analysis. …”
Get full text

Titanium nanotubes modulate immunophenotyping and cytokine secretion of T cells via IL-17A: a bioinformatic analysis and experimental validation by Jingju Yin, Jingju Yin, Jingju Yin, Jingju Yin, Yunyang Liao, Yunyang Liao, Yunyang Liao, Yunyang Liao, Shaofeng Liu, Shaofeng Liu, Shaofeng Liu, Shaofeng Liu, Bangwei Che, Hanghang Zhu, Hanghang Zhu, Bingbing Yang, Bingbing Yang, Bingbing Yang, Bingbing Yang, Bin Shi, Bin Shi

“…The proliferation and expressions of the main transcription factors and cytokines of T-cells were detected. Magnetic bead sorting of CD3+ T cells and transcriptome sequencing were performed to explore the signaling pathways and key immune factors that may influence the related immune responses.ResultsBioinformatics analysis showed that healthy peri-implant tissues were enriched by the most of T-cell subtypes. …”
Get full text

Microplastic analysis in soils: A comparative assessment by Stoyana Peneva, Quynh Nhu Phan Le, Davi R. Munhoz, Olivia Wrigley, Flora Wille, Heidi Doose, Crispin Halsall, Paula Harkes, Michael Sander, Melanie Braun, Wulf Amelung

“…We compared analytical protocols for MiP quantification in soil, consisting of Digital, Fluorescence, Fourier-transform infrared (FTIR), and Raman Microscopy as well as quantitative Pyrolysis-Gas Chromatography-Mass Spectroscopy (Py-GC-MS) and 1-proton nuclear magnetic resonance (1H NMR) spectroscopy as detection techniques. …”
Get full text

Functionality of endothelial cells differentiated from porcine epiblast stem cells, bone marrow-derived mesenchymal stem cells and adipose-derived mesenchymal stem cells by Yeon-Ji Lee, In-Won Lee, Tae-Suk Kim, Bo-Gyeong Seo, Sang-Ki Baek, Cheol Hwangbo, Joon-Hee Lee

“…Cells differentiated from these stem cells were isolated using CD-31 positive (+) magnetic-activated cell sorting (MACS) and then proliferated in M199 medium. …”
Get full text

Investigating the impact of microbiome-changing interventions on food decision-making: MIFOOD study protocol by Meghedi Vartanian, Konrad Jakob Endres, Yee Teng Lee, Silke Friedrich, Marie-Theres Meemken, Imke Schamarek, Kerstin Rohde-Zimmermann, Robin Schürfeld, Lina Eisenberg, Anja Hilbert, Frauke Beyer, Michael Stumvoll, Julia Sacher, Arno Villringer, Julia F. Christensen, A. Veronica Witte

“…Key inclusion criteria are 18–60 years of age and exclusion criteria are type 2 diabetes, psychiatric disease, and Magnetic Resonance Imaging (MRI) contraindications. …”
Get full text

Treatment time and learning curve analysis of 1.5 T MR-Linac workflows led by radiation oncologists or therapists by J.M. Westerhoff, F.J. Raaijmakers, L.A. Daamen, E.N. de Groot-van Breugel, L.T.C. Meijers, J.R.N. van der Voort van Zyp, J.J.C. Verhoeff, S. Mook, H.M. Verkooijen, M.P.W. Intven

“…Adapt-to-Position, ATP) magnetic resonance guided radiotherapy (MRgRT) on a 1.5 Tesla MR-Linac. …”
Get full text

Cardiovascular risk burden, dementia risk and brain structural imaging markers: a study from UK Biobank by Ting Li, Jing Chen, Yan Zheng, Klodian Dhana, Geng Zong, Yuan Ma, Trudy Voortman, Wei Gan, Yaying Cao, Yonghua Hu, Changzheng Yuan, Jie Shen, Gaohong Zhu, Chengwu Feng

“…Background Cardiovascular risk burden is associated with dementia risk and neurodegeneration-related brain structure, while the role of genetics and incident cardiovascular disease (CVD) remains unclear.Aims To examine the association of overall cardiovascular risk burden with the risk of major dementia subtypes and volumes of related brain regions in a large sample, and to explore the role of genetics and CVD onset.Methods A prospective study among 354 654 participants free of CVD and dementia (2006–2010, mean age 56.4 years) was conducted within the UK Biobank, with brain magnetic resonance imaging (MRI) measurement available for 15 104 participants since 2014. …”
Get full text

Age-related differences in long-term potentiation-like plasticity and short-latency afferent inhibition and their association with cognitive function by Tong Wang, Ying Shen, Tianjiao Zhang, Chuan He, Qian Lu, Jie Song, Manyu Dong, Yilun Qian, Sisi Huang, Jing Teng

“…Background The neurophysiological differences in cortical plasticity and cholinergic system function due to ageing and their correlation with cognitive function remain poorly understood.Aims To reveal the differences in long-term potentiation (LTP)-like plasticity and short-latency afferent inhibition (SAI) between older and younger individuals, alongside their correlation with cognitive function using transcranial magnetic stimulation (TMS).Methods The cross-sectional study involved 31 younger adults aged 18–30 and 46 older adults aged 60–80. …”
Get full text

Determining the incidence, risk factors and biological drivers of irritable bowel syndrome (IBS) as part of the constellation of postacute sequelae of SARS-CoV-2 infection (PASC) o... by Erika Austhof, Kelly M Heslin, Xiaoxiao Sun, Kristen Pogreba Brown, Caitlyn M McFadden, Caroline Scranton, Ivan Vujkovic-Cviji, Dominic Rodriguez, Laura Falk, Gayatri Arani, Victoria Obergh, Kate Bessey, Kerry Cooper

“…Both samples will undergo a novel method to quantitate humoral and mucosal immune responses to host-derived faecal communities in conjunction with magnetic bead-based separation and high-depth shotgun microbial sequencing. …”
Get full text

Abdominal synthetic CT generation for MR-only radiotherapy using structure-conserving loss and transformer-based cycle-GAN by Chanwoong Lee, Chanwoong Lee, Young Hun Yoon, Young Hun Yoon, Young Hun Yoon, Jiwon Sung, Jun Won Kim, Yeona Cho, Jihun Kim, Jaehee Chun, Jin Sung Kim, Jin Sung Kim, Jin Sung Kim

“…PurposeRecent deep-learning based synthetic computed tomography (sCT) generation using magnetic resonance (MR) images have shown promising results. …”
Get full text

A New Transformation Method of the T₂ Spectrum Based on Ordered Clustering—A Case Study on the Pore-Throat Utilization Rule of Supercritical CO₂ Flooding in L... by Yanchun Su, Chunhua Zhao, Xianjie Li, Xiujun Wang, Jian Zhang, Bo Huang, Xiaofeng Tian, Mingxi Liu, Kaoping Song

“…Nuclear magnetic resonance (NMR) and high-pressure mercury injection (HPMI) have been widely used as common characterization methods of pore-throat. …”
Get full text

Altered medial temporal lobe subregion volumes in systemic lupus erythematosus patients with neuropsychiatric symptoms by Z. Makdad Najeeb, P. C. Sundgren, A. Jönsen, K. Zervides, J. Lätt, T. Salomonsson, J. Nystedt, P. Nilsson, A. Bengtsson, G. Kuchcinski, L. E. M. Wisse

“…Abstract Background Systemic lupus erythematosus (SLE) often presents with neuropsychiatric (NP) involvement, including cognitive impairment and depression. Past magnetic resonance imaging (MRI) research in SLE patients showed smaller hippocampal volumes but did not investigate other medial temporal lobe (MTL) regions. …”
Get full text

Predicting Axillary Lymph Node Metastasis in Young Onset Breast Cancer: A Clinical-Radiomics Nomogram Based on DCE-MRI by Dong X, Meng J, Xing J, Jia S, Li X, Wu S

“…Precisely forecasting axillary lymph node metastasis (ALNM) is essential for customizing treatment plans and enhancing patient results.Objective: This research sought to create and verify a clinical-radiomics nomogram that combines radiomic features from Dynamic Contrast-Enhanced Magnetic Resonance Imaging (DCE-MRI) with standard clinical predictors to improve the accuracy of predicting ALNM in young breast cancer patients.Methods: We performed a retrospective analysis at one facility, involving the creation and validation of a nomogram in two stages.At first, a medical model was developed utilizing conventional indicators like tumor dimensions, molecular classifications, multifocal presence, and MRI-determined ALN status.A more detailed clinical-radiomics model was subsequently developed by integrating radiomic characteristics derived from DCE-MRI images.These models were created using logistic regression analyses on a training dataset, and their effectiveness was assessed by measuring the area under the receiver operating characteristic curve (AUC) in a separate validation dataset.Results: The clinical-radiomics nomogram surpassed the clinical-only model, recording an AUC of 0.892 in the training dataset and 0.877 in the validation dataset.Significant predictors included MRI-reported ALN status and select radiomic features, which markedly enhanced the model’s predictive capacity.Conclusion: Integrating radiomic features with clinical predictors in a nomogram significantly improves ALNM prediction in young onset breast cancer, providing a valuable tool for personalized treatment planning. …”
Get full text

Comparative study of arthroscopic autologous cancellous bone grafting and medial malleolar osteotomy combined with autologous periosteal iliac bone grafting for the treatment of os... by Xinyu Tang, Xinkun Han, Haitao Fu, Youliang Shen, Dongfang Zhang, Qinwei Guo, Chao Qi

“…Compared the surgical time of the two groups; the visual analog scale (VAS) scores, American Orthopaedic Foot & Ankle Society (AOFAS) scores, and ankle joint mobility were used preoperatively, and at 3 months and 1 year postoperatively to assess clinical efficacy; the magnetic resonance observation of cartilage repair tissue (MOCART) 2.0 ankle scores were evaluated at early postoperatively and 1 year postoperatively to assess cartilage repair. …”
Get full text