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101
A Systematic Review of Deep Learning Methods Applied to Ocular Images
Published 2019-11-01“…On the one hand, these methods have achieved an outstanding performance in the detection of ocular diseases such as: diabetic retinopathy, glaucoma, diabetic macular degeneration and age-related macular degeneration. …”
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102
Significance of Hyperreflective Foci as an Optical Coherence Tomography Biomarker in Retinal Diseases: Characterization and Clinical Implications
Published 2021-01-01“…Despite this, HRF can be considered OCT biomarkers for disease progression, treatment response, and prognosis in several retinal diseases, including diabetic macular edema, age-related macular degeneration (AMD), retinal vascular occlusions, and inherited retinal dystrophies. …”
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103
Effect of Intravitreal Ranibizumab in the Treatment of Peripapillary Choroidal Neovascularisation
Published 2011-01-01“…Intravitreal ranibizumab therapy is widely used in treatment of subfoveal choroidal neovascularisation (CNV) in age-related macular degeneration. We wanted to study the effect of intravitreal ranibizumab therapy in peripapillary CNV. …”
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104
High-Resolution Optical Coherence Tomography Retinal Imaging: A Case Series Illustrating Potential and Limitations
Published 2011-01-01“…The series comprised four selected cases (one case each) of age-related macular degeneration (ARMD), diabetic retinopathy (DR), central retinal artery occlusion (CRAO), and branch retinal vein occlusion (BRVO). …”
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105
Nonsteroidal Anti-Inflammatory Drugs for Retinal Disease
Published 2013-01-01“…For example, therapeutic effects on diabetic retinopathy and age-related macular degeneration may now be achievable. We provide an updated review on the scientific rationale and clinical use of NSAIDs for retinal disease.…”
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106
Ocular diseases of the anterior segment and adnexa in the elderly
Published 2024-02-01“…High blood pressure (37.4%) and age-related macular degeneration (27.6%) were evident. Decreased visual acuity occurred in 69.1% and cataract was the predominant disease (43.9%). …”
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107
Cell Therapy for Retinal Dystrophies: From Cell Suspension Formulation to Complex Retinal Tissue Bioengineering
Published 2019-01-01“…Retinal degeneration is an irreversible phenomenon caused by various disease conditions including age-related macular degeneration (AMD) and retinitis pigmentosa (RP). …”
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108
Recent Advances and the Mechanism of Astaxanthin in Ophthalmological Diseases
Published 2022-01-01“…This article reviews the function and the potential mechanism of AST in dry eye syndrome, keratitis, cataract, diabetic retinopathy, age-related macular degeneration, high intraocular pressure, and other ocular diseases. …”
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109
Lutein and inflammation: a comprehensive review of its mechanisms of action
Published 2025-01-01“…Additionally, it discusses lutein’s beneficial impact on macular degeneration and eye diseases, showcasing its potential as a natural, plant-based therapeutic agent.…”
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110
Lutein, Zeaxanthin, and meso-Zeaxanthin in the Clinical Management of Eye Disease
Published 2015-01-01“…Observational studies have reported that increased dietary intake and higher serum levels of lutein and zeaxanthin are associated with lower risk of age-related macular degeneration (AMD), especially late AMD. Randomized, placebo-controlled clinical trials have demonstrated that xanthophyll supplementation increases macular pigment levels, improves visual function, and decreases the risk of progression to late AMD, especially neovascular AMD. …”
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111
Therapeutic Effect of Oral Bisphosphonates on Choroidal Neovascularization in the Human Eye
Published 2010-01-01“…Choroidal neovascularization (CNV) is often associated with age-related macular degeneration (AMD) and pathological myopia (PM). …”
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112
Inhibiting the alternative pathway of complement by reducing systemic complement factor B: Randomized, double-blind, placebo-controlled phase 1 studies with Sefaxersen
Published 2025-03-01“…These clinical results support the ongoing Phase 2 development for geographic atrophy secondary to age-related macular degeneration and Ph 2/3 development for IgA nephropathy.…”
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113
Overexpression of MiR-183/96/182 Triggers Retina-Like Fate in Human Bone Marrow-Derived Mesenchymal Stem Cells (hBMSCs) in Culture
Published 2019-01-01“…Retinal degeneration is considered as a condition ensued by different blinding disorders such as retinitis pigmentosa, age-related macular degeneration, and diabetic retinopathy, which can cause loss of photoreceptor cells and also lead to significant vision deficiencies. …”
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114
Systems Biology Profiling of AMD on the Basis of Gene Expression
Published 2013-01-01“…Genetic pathways underlying the initiation and progression of age-related macular degeneration (AMD) have not been yet sufficiently revealed, and the correlations of AMD’s genotypes, phenotypes, and disease spectrum are still awaiting resolution. …”
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115
Anti-VEGF Treatment Strategies for Wet AMD
Published 2012-01-01“…Over the past few years, antivascular endothelial growth factor (VEGF) therapy has become a standard treatment for neovascular age-related macular degeneration (AMD). During this time, treatment strategies have evolved from a monthly dosing schedule to individualized regimens. …”
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116
Focal Choroidal Elevations: Localized Pigment Epithelial Contour Alterations due to Isolated Choroidal Vessels
Published 2019-01-01“…FCE were observed in 25 patients with age-related macular degeneration (ARMD), in 5 patients with high myopia, and in 8 patients with age-related choroidal atrophy (ARCA). …”
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117
Histological Characterization of the Dicer1 Mutant Zebrafish Retina
Published 2015-01-01“…DICER1 was recently shown to have another function of silencing the toxicity of Alu RNAs in retinal pigment epithelium (RPE) cells, which are involved in the pathogenesis of age related macular degeneration. In this study, we characterized a Dicer1 mutant fish line, which carries a nonsense mutation (W1457Ter) induced by N-ethyl-N-nitrosourea mutagenesis. …”
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118
Sustained Intraocular Pressure Rise after the Treat and Extend Regimen at 3 Years: Aflibercept versus Ranibizumab
Published 2020-01-01“…Patients. 789 patients (1021 eyes; 602 males) enrolled in T&E using aflibercept/ranibizumab for diabetic macular edema (DME), wet age-related macular degeneration (AMD), or macular edema in retinal vein occlusion (RVO). …”
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119
Management of Uveitis-Related Choroidal Neovascularization: From the Pathogenesis to the Therapy
Published 2014-01-01“…Its pathogenesis is supposed to be similar to the wet age related macular degeneration: hypoxia, release of vascular endothelial growth factor, stromal cell derived factor 1-alpha, and other mediators seem to be involved in the uveitis-related choroidal neovascularization. …”
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120
Examining the Choroid in Ocular Inflammation: A Focus on Enhanced Depth Imaging
Published 2014-01-01“…The choroid is the vascular layer that supplies the outer retina and is involved in the pathogenesis of several ocular conditions including choroidal tumors, age related macular degeneration, central serous chorioretinopathy, diabetic retinopathy, and uveitis. …”
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