Macrophages Are Key Regulators of Stem Cells during Skeletal Muscle Regeneration and Diseases by Junio Dort, Paul Fabre, Thomas Molina, Nicolas A. Dumont

“…Among these different cell types, macrophages emerged as a central actor coordinating the different cellular interactions and biological processes. …”
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Peroxisome Proliferator-Activated Receptor-γ-Mediated Polarization of Macrophages in Leishmania Infection by Marion M. Chan, Nagasuresh Adapala, Cui Chen

“…In the disease leishmaniasis, the causative protozoan parasites are harbored inside the macrophages. Leishmania species adapt strategies to make the infection chronic, keeping a balance between their own and the host's defense so as to establish an environment that is favorable for survival and propagation. …”
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Adhered macrophages as an additional marker of cardiomyocyte injury in biopsies of patients with dilated cardiomyopathy by Warmusz Oliwia, Badziński Arkadiusz, Reichman-Warmusz Edyta, Dudek Damian, Wojnicz Romuald

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Understanding the Mysterious M2 Macrophage through Activation Markers and Effector Mechanisms by Tamás Rőszer

“…Today the M2 macrophages are identified based on the expression pattern of a set of M2 markers. …”
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Unraveling the immunomodulatory and metabolic effects of bioactive glass S53P4 on macrophages in vitro by Karoliina Kajander, Nicole Nowak, Negin Vaziri, Pekka K. Vallittu, Terhi J. Heino, Jorma A. Määttä

“…Abstract Macrophage metabolism is closely linked to their phenotype and function, which is why there is growing interest in studying the metabolic reprogramming of macrophages. …”
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Apigenin inhibits NLRP3 inflammasome activation in monocytes and macrophages independently of CD38 by Knut Husø Lauritzen, Knut Husø Lauritzen, Kuan Yang, Michael Frisk, Mieke C. Louwe, Maria Belland Olsen, Maria Belland Olsen, Mathias Ziegler, William E. Louch, Bente Halvorsen, Bente Halvorsen, Pål Aukrust, Pål Aukrust, Arne Yndestad, Øystein Sandanger, Øystein Sandanger

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A Proinflammatory Effect of the β-Glucan from Pleurotus cornucopiae Mushroom on Macrophage Action by Ken-ichiro Minato, Akihiro Ohara, Masashi Mizuno

“…However, the PCPS did not induce to express both IL-12 and IL-10 mRNA in the macrophages. Next, the P. cornucopiae extract (containing mainly PCPS) treatment against mice showed significant increases in TNF and IL-1β mRNA expressions in the peritoneal macrophages of them. …”
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Role of Acetylsalicylic Acid in Cytokine Stimulation of Macrophages in Antibody-Dependent Cellular Cytotoxicity (ADCC) by M. Jäpel, H. Lötzerich, K. Rogalla

“…The action of ASA on the activity of mouse peritoneal macrophages was therefore investigated in the present study. …”
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Targeted Imaging of Tumor-Associated Macrophages by Cyanine 7-Labeled Mannose in Xenograft Tumors by Chong Jiang MD, Huawei Cai PhD, Xiaodong Peng MD, Ping Zhang PhD, Xiaoai Wu PhD, Rong Tian MD

“…Mannose receptor is considered as a hallmark of M2-oriented tumor-associated macrophages (TAMs), but its utility in TAMs was rarely reported. …”
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Tumor-associated macrophages contribute to cholangiocarcinoma progression and chemoresistance through activation of ID1 by Yinghao Guo, Shuangda Miao, Yun Jin, Qi Li, Yihang Wang, Xiaoxiao Zhang, Jiangtao Li

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The Crosstalk between Mesenchymal Stem Cells and Macrophages in Bone Regeneration: A Systematic Review by Rita Lih-Ying Shin, Chien-Wei Lee, Oscar Yuan-Jie Shen, Hongtao Xu, Oscar Kuang-Sheng Lee

“…However, the precise mechanisms by which macrophage subtypes influence bone regeneration and how MSCs communicate with macrophages have not yet been fully elucidated. …”
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Macrophages infiltration and oral potentially malignant disorders: A systematic review and meta-analysis by Lara Krusser Feltraco, Julia Rodrigues Fernandes, Leonardo Francisco Diel, Leonardo da Silva Bittencourt, Lisiane Bernardi, Marcelo Lazzaron Lamers

“…Since oral squamous cell carcinoma shows an association between macrophages and a worse prognosis, we hypothesize that macrophages could also be involved in the evolution of oral potentially malignant disorders into oral squamous cell carcinoma. …”
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Macrophage activation syndrome in a patient with systemic lupus erythematous triggered by tuberculous meningitis by Noura Alowais, Noura Zamani, Faisal Elbadawi, Hassan Ahmed, Pankhi Dutta, Aesha Sharif

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The venom of South American rattlesnakes inhibits macrophage functions and is endowed with anti-inflammatory properties by Maria C. C. de Sousa e Silva, Luis R. C. Gonçalves, Mario Mariano

“…This effect was not observed when the venom was added to cultures of thioglycollate elicited macrophages, but it was able to inhibit these macrophage functions when the cells were obtained from animals injected simultaneously with the venom and thioglycollate. …”
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Sodium butyrate regulates macrophage polarization by TGR5/β-arrestin2 in vitro by Miao Liu, Wen-jie Xie, Xu Zhang, Wei Wu, Guang Li, Lu Wang

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Expression of CD68+ Tumor associated macrophages in relation to β-catenin in carcinoma stomach by Nikhil Sharma, Ranjita Panigrahi, Prita Pradhan, Sabyasachi Parida, Saroj R. Sahoo

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Angiotensin-(1-7) and Alamandine Promote Anti-inflammatory Response in Macrophages In Vitro and In Vivo by Melissa de Carvalho Santuchi, Miriane Fernandes Dutra, Juliana Priscila Vago, Kátia Maciel Lima, Izabela Galvão, Fernando Pedro de Souza-Neto, Mario Morais e Silva, Aline Cristina Oliveira, Flávia Carvalho Bittencourt de Oliveira, Ricardo Gonçalves, Mauro Martins Teixeira, Lirlândia Pires Sousa, Robson Augusto Souza dos Santos, Rafaela Fernandes da Silva

“…However, the effects of RAS peptides on different macrophage phenotypes are still emerging. Here, we evaluated the effects of angiotensin-(1-7) (Ang-(1-7)) and the most novel RAS peptide, alamandine, on resting (M0), proinflammatory M(LPS+IFN-γ), and anti-inflammatory M(IL-4) macrophage phenotypes in vitro, as well as on specific immune cell populations and macrophage subsets into the pleural cavity of LPS-induced pleurisy in mice. …”
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Modulation of Stat-1 in Human Macrophages Infected with Different Species of Intracellular Pathogenic Bacteria by Giuditta Fiorella Schiavano, Sabrina Dominici, Laura Rinaldi, Alfonsina Mariarosaria Cangiano, Giorgio Brandi, Mauro Magnani

“…The infection of human macrophages by pathogenic bacteria induces different signaling pathways depending on the type of cellular receptors involved in the microorganism entry and on their mechanism(s) of survival and replication in the host cell. …”
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Inosine Prevents Colorectal Cancer Progression by Inducing M1 Phenotypic Polarization of Macrophages by Yuchen Ma, Xiaoli Qian, Qun Yu, Yadan Dong, Jiapeng Wang, Heng Liu, Huai Xiao

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Nucleotides Regulate Secretion of the Inflammatory Chemokine CCL2 from Human Macrophages and Monocytes by K. R. Higgins, W. Kovacevic, L. Stokes

“…The extracellular nucleotide signalling molecules UTP and ATP acting via the P2Y2 receptor are known to induce CCL2 secretion in macrophages. We confirmed this in the human THP-1 monocytic cell line showing that UTP is as efficient as LPS at inducing CCL2 at early time points (2–6 hours). …”
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