Sodium butyrate regulates macrophage polarization by TGR5/β-arrestin2 in vitro by Miao Liu, Wen-jie Xie, Xu Zhang, Wei Wu, Guang Li, Lu Wang

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Expression of CD68+ Tumor associated macrophages in relation to β-catenin in carcinoma stomach by Nikhil Sharma, Ranjita Panigrahi, Prita Pradhan, Sabyasachi Parida, Saroj R. Sahoo

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Angiotensin-(1-7) and Alamandine Promote Anti-inflammatory Response in Macrophages In Vitro and In Vivo by Melissa de Carvalho Santuchi, Miriane Fernandes Dutra, Juliana Priscila Vago, Kátia Maciel Lima, Izabela Galvão, Fernando Pedro de Souza-Neto, Mario Morais e Silva, Aline Cristina Oliveira, Flávia Carvalho Bittencourt de Oliveira, Ricardo Gonçalves, Mauro Martins Teixeira, Lirlândia Pires Sousa, Robson Augusto Souza dos Santos, Rafaela Fernandes da Silva

“…However, the effects of RAS peptides on different macrophage phenotypes are still emerging. Here, we evaluated the effects of angiotensin-(1-7) (Ang-(1-7)) and the most novel RAS peptide, alamandine, on resting (M0), proinflammatory M(LPS+IFN-γ), and anti-inflammatory M(IL-4) macrophage phenotypes in vitro, as well as on specific immune cell populations and macrophage subsets into the pleural cavity of LPS-induced pleurisy in mice. …”
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Modulation of Stat-1 in Human Macrophages Infected with Different Species of Intracellular Pathogenic Bacteria by Giuditta Fiorella Schiavano, Sabrina Dominici, Laura Rinaldi, Alfonsina Mariarosaria Cangiano, Giorgio Brandi, Mauro Magnani

“…The infection of human macrophages by pathogenic bacteria induces different signaling pathways depending on the type of cellular receptors involved in the microorganism entry and on their mechanism(s) of survival and replication in the host cell. …”
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Nucleotides Regulate Secretion of the Inflammatory Chemokine CCL2 from Human Macrophages and Monocytes by K. R. Higgins, W. Kovacevic, L. Stokes

“…The extracellular nucleotide signalling molecules UTP and ATP acting via the P2Y2 receptor are known to induce CCL2 secretion in macrophages. We confirmed this in the human THP-1 monocytic cell line showing that UTP is as efficient as LPS at inducing CCL2 at early time points (2–6 hours). …”
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The Effect of Lithium on Inflammation-Associated Genes in Lipopolysaccharide-Activated Raw 264.7 Macrophages by Raymond T. Makola, Vusi G. Mbazima, Matlou P. Mokgotho, Vincent S. Gallicchio, Thabe M. Matsebatlela

“…Moreover, lithium inhibits NF-κB activity by lowering nuclear translocation of NF-κB in LPS-activated macrophages. This is the first study to associate Tollip, Traf-3, and IκB-α mRNA expression with lithium effect on NF-κB activity in LPS-activated Raw 264.7 macrophages. …”
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Blimp-1 orchestrates macrophage polarization and metabolic homeostasis via purine biosynthesis in sepsis by Wenjuan Peng, Qiushi Qin, Rui Li, Yujia Liu, Lan Li, Yue Zhang, Liuluan Zhu

“…This study aimed to elucidate the role of Blimp-1 in macrophage polarization and metabolism during sepsis. …”
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Monocyte and Macrophage in Follicular Liquid: Predictive Markers of Embryo Quality in Women with Obesity and Infertility by Evgeny D. Merkulov, Anastasia V. Prozorova, Iuliia G. Samoilova, Dmitry A. Svarovsky, Kira A. Sidorenkova, Liudmila V. Spirina, Marina N. Stakheeva, Oxana S. Timofeeva, Ilya A. Petrov

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Oxidized LDL Induces Alternative Macrophage Phenotype through Activation of CD36 and PAFR by Francisco J. Rios, Marianna M. Koga, Mateus Pecenin, Matheus Ferracini, Magnus Gidlund, S. Jancar

“…Since PAFR in macrophages is associated with suppressor function, we examined the effect of oxLDL on macrophage phenotype. …”
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Optimized Method to Generate Well-Characterized Macrophages from Induced Pluripotent Stem Cells by Qimin Hai, Peter Bazeley, Juying Han, Gregory Brubaker, Jennifer Powers, Claudia M. Diaz-Montero, Jonathan D. Smith

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Retinal Surface Macrophage Changes in Thyroid Eye Disease before and after Treatment with Teprotumumab by Oscar Otero-Marquez, Mona Fayad, Alexander Pinhas, Toco Y. P. Chui, Richard B. Rosen, Harsha S. Reddy

“…Retinal surface macrophages play key roles in the regulation of immune response, maintenance of vitreous clarity, and tissue repair. …”
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Plasma macrophage colony-stimulating factor levels during cardiopulmonary bypass with extracorporeal circulation by Y. Denizot, P. Fixe, E. Cornu, N. Nathan

“…Elevated circulating concentrations of macrophage colony-stimulating factor (M-CSF) are reported during thrombocytopenia and leukopenia of different origins. …”
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Cholecystokinin Inhibits Inducible Nitric Oxide Synthase Expression by Lipopolysaccharide-Stimulated Peritoneal Macrophages by Rafael Simone Saia, Fabíola Leslie Mestriner, Giuliana Bertozi, Fernando Queiróz Cunha, Evelin Capellari Cárnio

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Role of lysosomal enzymes released by alveolar macrophages in the pathogenesis of the acute phase of hypersensitivity pneumonitis by J. L. Pérez-Arellano, M. N. Barrios, T. Martín, M. L. Sánchez, J. M. González Buitrago, A. Jiménez

“…Hydrolytic enzymes are the major constituents of alveolar macrophages (AM) and have been shown to be involved in many aspects of the inflammatory pulmonary response. …”
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Reducing M2 macrophage in lung fibrosis by controlling anti-M1 agent by Fatemeh Bahram Yazdroudi, Alaeddin Malek

“…The numerical simulations indicate that without control, M2 macrophage levels increase and stabilize, contributing to fibrosis. …”
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Dual-mode-driven nanomotors targeting inflammatory macrophages for the MRI and synergistic treatment of atherosclerosis by Min Wei, Qiaoji Jiang, Shuang Bian, Pengzhao Chang, Bangbang Li, Changzhou Shi, Yangang Zhu, Yanchen Wang, Pingfu Hou, Jingjing Li

“…Near-infrared (NIR) laser irradiation promoted the photothermal conversion of Gd-MCNs to generate the thermal propulsion of nanomotor and photothermal ablation of inflammatory macrophages. Meanwhile, the modification of AntiCD36 to bind with inflammatory macrophages further promotes the targeting effect. …”
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Inflammation and ER Stress Downregulate BDH2 Expression and Dysregulate Intracellular Iron in Macrophages by Susu M. Zughaier, Brandon B. Stauffer, Nael A. McCarty

“…Macrophages play a very important role in host defense and in iron homeostasis by engulfing senescent red blood cells and recycling iron. …”
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Placental malaria infection is associated with downregulation of STAT-6 and ANG-1 in decidual macrophages by Fred Owino, Fred Owino, Fred Owino, Caroline Kijogi, Caroline Kijogi, Caroline Kijogi, Omu Anzala, Omu Anzala, Edwin Walong, Obiero Jael, Steven G. Nyanjom, Agola Lelo Eric, Bernard N. Kanoi, Bernard N. Kanoi, Jesse Gitaka, Jesse Gitaka

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Nonylphenol exposure increases the risk of Hirschsprung’s disease by inducing macrophage M1 polarization by Xuefeng Yang, Chengyan Tang, Daiwei Zhu, Xingrong Xia, Qing Du, Lu Huang, Jianguo Liu, Yuanmei Liu

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The injectable hydrogel loading cannabidiol to regulate macrophage polarization in vitro for the treatment of chronic enteritis by Ye Wang, Xingming Ji, Xinyi Wang, Mengyu Sun, Cheng Li, Dongmei Wu

“…Results: Our study found that GelMA + CBD with biosafety, could make CBD be slowly released, and effectively inhibit the M1-type polarization of macrophages in vitro, and promote the M2-type polarization. …”
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