Saving Death: Apoptosis for Intervention in Transplantation and Autoimmunity by Alice Li, Okechukwu Ojogho, Alan Escher

“…The role of apoptosis in immunological homeostasis has been inferred from several findings, for example, induction of tolerance after injection of apoptotic cells and the capacity of APCs like macrophages and DCs to induce and maintain tolerance after phagocytosis of dead cells. …”
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ZNF521 Is Correlated with Tumor Immune Cell Infiltration and Act as a Valuable Prognostic Biomarker in Gastric Cancer by Li Li, Zheng-Hui Liu, Hui-Ju Wang, Lei Wang, Guo-Qing Ru, Yuan-Yu Wang

“…The expression of ZNF521 was correlated with infiltrating levels of CD4+ T and CD8+ T cells, macrophages, neutrophils, and dendritic cells in gastric cancer, which also correlated with diverse immune marker sets. …”
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PD-L1 knockout or ZG16 overexpression inhibits PDAC progression and modulates TAM polarization by Hui Meng, Manman Nan, Yizhen Li, Yi Ding, Xiaokun Fang, Weiqian Ma, Mingzhi Zhang

“…Both methods promoted the polarization of tumor-associated macrophages (TAMs) to the M1 phenotype, as indicated by increased levels of the M1 marker CD11c+ in vitro and in vivo. …”
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HIV-1 Trans Infection of CD4+ T Cells by Professional Antigen Presenting Cells by Charles R. Rinaldo

“…Since the 1990s we have known of the fascinating ability of a complex set of professional antigen presenting cells (APCs; dendritic cells, monocytes/macrophages, and B lymphocytes) to mediate HIV-1 trans infection of CD4+ T cells. …”
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Glucocorticosteroid in Treatment of Severe Pneumonia by Felinda Ariani, Kaixiong Liu, Zhang Jing, Jieming Qu

“…The balance between inflammatory mediators is key for the outcome of the pulmonary infection; elimination of invading pathogen was marked by the release of cytokines and other inflammatory mediators from alveolar macrophages and glucocorticoid steroids (GCs) acting on the inflammatory component. …”
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Hemophagocytic Syndrome Associated with Mycoplasma pneumoniae Pneumonia by Yuji Koike, Nao Aoki

“…Furthermore, a peripheral blood smear showed an increased number of monocytes/macrophages with erythrophagocytosis. Treatment with clarithromycin and prednisolone, which was initiated soon after the diagnosis, was successful. …”
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Innate Immune Memory: The Latest Frontier of Adjuvanticity by Elfi Töpfer, Diana Boraschi, Paola Italiani

“…Upon infection or vaccination, monocytes/macrophages can be functionally reprogrammed so as to display an enhanced defensive response against unrelated infections. …”
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Live Combined Bacillus subtilis and Enterococcus faecium Ameliorate Murine Experimental Colitis by Immunosuppression by S. Chen, Y. Fu, L. L. Liu, W. Gao, Y. L. Liu, S. H. Fei, Y. Tan, K. F. Zou

“…Live combined Bacillus subtilis and Enterococcus faecium ameliorate murine experimental colitis by immunosuppression manifested by downregulation of TLRs, macrophages, Th1, and Th2 but upregulation of Tregs.…”
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The Role of CARD9 Deficiency in Neutrophils by Ruanmei Sheng, Xiaoming Zhong, Zhiwen Yang, Xuemin Wang

“…Of note, CARD9, a myeloid cell-specific signaling protein that mainly expresses in macrophages and dendritic cells, is also present in neutrophils, emerging as a critical mediator for intercellular communication. …”
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Innate Immune Cells in Liver Inflammation by Evaggelia Liaskou, Daisy V. Wilson, Ye H. Oo

“…In order to achieve this, the liver innate immune system is equipped with multiple cellular components; monocytes, macrophages, granulocytes, natural killer cells, and dendritic cells which coordinate to exert tolerogenic environment at the same time detect, respond, and eliminate invading pathogens, infected or transformed self to mount immunity. …”
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Free Radical Scavenging Capacities and Alleviating Actions of Polysaccharides Extract of Termitomyces le-testui on Methylprednisolone-Induced Immunodepression in Rats by Foncham Evans Ngwenah, Kada Sanda Antoine, Salah Martin, Tume Christopher, Oumar Mahamat

“…The result of the study showed that the polysaccharide T. le-testui increases the phagocytic index, energy metabolism of macrophages, spleen index, and nitric oxide in a concentration-dependent manner in immunosuppressed animals. …”
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Rare cause of chronic cough in a young healthcare worker - A case of exogenous lipoid pneumonia! by Nandini Dikshit, Mansi Gupta, Neha Nigam, Alok Nath

“…ELP was diagnosed after carefully evaluating the radiological findings, reviewing the clinical history, and finding supportive evidence of lipid-laden alveolar macrophages in her broncho-alveolar lavage fluid. It is vital to uphold a heightened clinical suspicion for non-infectious etiologies in non-resolving pneumonia and investigate the patient thoroughly before resorting to empirical treatments.…”
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Histopathological and Immunohistochemical Evaluation of African Swine Fever Pigs in Bali Province by Monica Septiani, Vetnizah Juniantito, Bambang Pontjo Priosoeryanto

“…Immunohistochemistry consistently showed p54 viral antigen distribution in mononuclear cells/macrophages across various organs, with the spleen and lymph nodes being dominant sites in 12 pigs (100%). …”
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Studies on the Anti-Inflammatory Effect and Its Mechanisms of Sophoridine by Xiumei Huang, Bo Li, Lianzhong Shen

“…Excessive inflammatory response in vitro model was developed by using lipopolysaccharide (LPS) to stimulate the mouse peritoneal macrophages and HL-60 cells to produce IL-6 and IL-8. …”
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Tumor-Related Exosomes Contribute to Tumor-Promoting Microenvironment: An Immunological Perspective by Wuzhen Chen, Jingxin Jiang, Wenjie Xia, Jian Huang

“…They can interfere with the maturation of DC cells, impair NK cell activation, induce myeloid-derived suppressor cells, and educate macrophages into protumor phenotype. They can also selectively induce effector T cell apoptosis via Fas/FasL interaction and enhance regulatory T cell proliferation and function by releasing TGF-β. …”
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New opinion on the issue of proton pump inhibitor-refractory gastroesophageal reflux disease by Yu. V. Yevsyutina, A. S. Trukhmanov

“…There is a disorder of the immune response as a disbalance between cellular and humoral components of immunity at GERD, that can be determined as phenotype of macrophages (М1 or М2), and other immune and non-immune cells.Conclusion. …”
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Urinothorax Caused by Xanthogranulomatous Pyelonephritis by Waiel Abusnina, Hazim Bukamur, Zeynep Koc, Fauzi Najar, Nancy Munn, Fuad Zeid

“…Its pathogenesis generally involves calculus obstructive uropathy and its histopathology is characterized by replacement of the renal parenchyma with lipid filled macrophages. This often manifests as an enlarged, nonfunctioning kidney that may be complicated by abscess or fistula. …”
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Overview of (1→3)-β-D-glucan immunobiology by David L. Williams

“…It is now established that (1→3)-β-D-glucans are recognized by macrophages and, perhaps, neutrophils and natural killer cells via a (1→3)-β-glucan specific receptor. …”
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Diagnosis of feline infectious peritonitis by immunohistochemistry and histopathology methods: a case report based on diagnostic approach by Mehmet Burak Ateş, Gökhan Akçakavak, Zeynep Çelik, Özgür Özdemir

“…Immunoreactivity was detected in the cytoplasm of macrophages in the liver, around both pyrogranulomas and granulomas. …”
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Transplantation Tolerance Induced in Humans at the Fetal or the Neonatal Stage by Jean-Louis Touraine, Kamel Sanhadji

“…The latter tolerance relies upon clonal deletion from the T-cell repertoire, and it results from the contact between thymocytes of donor origin and dendritic cells or macrophages also deriving from donor stem cells. The former tolerance does not imply clonal deletion of T-cells with host reactivity. …”
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