Chemokines and Neurodegeneration in the Early Stage of Experimental Ischemic Stroke by Pawel Wolinski, Andrzej Glabinski

“…It was observed that neurodegeneration appears very early in that model and correlates well with migration of inflammatory lymphocytes and macrophages to the brain. Although the expression of several studied chemotactic cytokines (chemokines) was significantly increased at the early phase of ET-1 induced stroke model, no clear correlation of this expression with neurodegeneration was observed. …”
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A Case of Disseminated Mycobacterium avium Infection in a Dog in Greece by V. Kontos, E. I. Papadogiannakis, G. Mantziaras, M. Styliara, S. Kanavaki

“…Cytology of fine-needle-aspiration material, obtained from popliteal lymph node, revealed macrophages with intracytoplasmic, nonstaining, slender, rod-like structures, indicative of mycobacteria. …”
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The role of TNF-α inhibitor in glioma virotherapy: A mathematical model by Elzbieta Ratajczyk, Urszula Ledzewicz, Maciej Leszczynski, Avner Friedman

“…But the innate immune response, which includes TNF-α produced by macrophages, reduces the effectiveness of the treatment. …”
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Emerging Roles of Immune Cells in Postoperative Cognitive Dysfunction by Yue Liu, Yiqing Yin

“…Microglia, bone marrow-derived macrophages, mast cells, and T cells in the central nervous system (CNS) can be activated to secrete more cytokines, further aggravating neuroinflammation after surgery. …”
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Association of Toll-Like Receptor Signaling and Reactive Oxygen Species: A Potential Therapeutic Target for Posttrauma Acute Lung Injury by Meng Xiang, Janet Fan, Jie Fan

“…Recent studies have reported that the mechanism underlying the priming of pulmonary inflammation involves the complicated cross-talk between Toll-like receptors (TLRs) and interactions between neutrophils (PMNs) and alveolar macrophages (AMϕ) as well as endothelial cells (ECs), in which reactive oxygen species (ROS) are the key mediator. …”
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Trypanosoma cruzi Infection and Host Lipid Metabolism by Qianqian Miao, Momar Ndao

“…Several players in host lipid metabolism have been implicated in T. cruzi-host interactions in recent research, including macrophages, adipocytes, low density lipoprotein (LDL), low density lipoprotein receptor (LDLR), and high density lipoprotein (HDL). …”
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Pulmonary nocardiosis in a fat-tailed sheep by Reza Kheirandish, Masoud Sami, Reza Ghanbarpour, Soodeh Alidadi

“…Microscopically, the nodules consisted of foci of pyogranulomatous inflammation with the presence of macrophages, multinucleated (langhans- type) giant cells and eosinophilic amorphous material with rosette-shape configurations (Splendore-Hoeppli reaction). …”
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Disruption of tumor-intrinsic PGAM5 increases anti-PD-1 efficacy through the CCL2 signaling pathway by Yan Li, Hong Wang, Xiaoyang Li, Yuan He, Huiquan Liu, Dong Han, Ting Mei, Yixuan Li, Zilong Xu, Xiaoying Wei, Jianguo Wang, Peijie Zhou, Yuwen Wang, Ziye Li, Junhao Ning, Anlin Wang, Jingjing Cheng, Dong Qian

“…Mechanistically, we established an in vitro co-culture system and analyzed proteomics data to find out the bridge between tumor cell PGAM5 and tumor-associated macrophages (TAMs) in the microenvironment. Immunofluorescence, chromatin-immunoprecipitation, ELISA, mass spectrometry were conducted to explore the molecular pathway. …”
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Altered Atlas of Exercise-Responsive MicroRNAs Revealing miR-29a-3p Attacks Armored and Cold Tumors and Boosts Anti-B7-H3 Therapy by Jie Mei, Zhiwen Luo, Yun Cai, Renwen Wan, Zhiwen Qian, Jiahui Chu, Yaying Sun, Yuxin Shi, Ying Jiang, Yan Zhang, Yongmei Yin, Shiyi Chen

“…Mechanistically, miR-29a-3p targeted macrophages, fibroblasts, and tumor cells to down-regulate B7 homolog 3 (B7-H3) expression. …”
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Construction of a novel cuproptosis-related gene signature and integrative analyses in cholangiocarcinoma by Liye Wang, Pan Li, Shuai Gong, Lina Pang, Mingyu Li, Chi Zhang, Shengli Zhang, Xiaoke Zhang, Guozhong Jiang, Wei He

“…The comprehensive results showed that a low-risk score was correlated with metabolism-related pathways, high infiltration of CD8 T cells, B cells, and M1 macrophages, active immunity and less aggressive phenotypes, high chemotherapeutic sensitivity, and more benefit from immunotherapy. …”
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Anti-inflammatory effect of Angiotensin 1-7 in white adipose tissue by Nozomi Nishida, Satoru Sugimoto, Satoshi Miyagaki, Chiharu Cho, Madoka Konishi, Takeshi Goda, Mihoko Yamaguchi, Yasuhiro Kawabe, Hidechika Morimoto, Joji Kusuyama, Takuro Okamura, Masahide Hamaguchi, Jun Mori, Hisakazu Nakajima, Michiaki Fukui, Tomoko Iehara

“…Furthermore, Ang 1–7 reduced MCP-1 and TNF-α secretions in 3T3-L1 white adipocytes and RAW 264.7 macrophages, respectively, which are in vitro experimental models mimicking obesity condition. …”
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Immune microenvironment features underlying the superior efficacy of neoadjuvant immunochemotherapy over chemotherapy in local advanced gastric cancer by Ning Zhang, Chunyu Li, Zehua Zhao, Biying Jiang, Wentao Wang, Fujing Sun, Yong Zhang, Yanmei Zhu

“…Tumor tissues were evaluated for tumor-infiltrating immune cells (TIICs) using immunohistochemistry and QuPath software quantitative analysis, for detecting T, B, NK, plasma cells, and macrophages. The relationship between TIICs and different neoadjuvant treatment regimens and pathological responses was also explored.ResultsCompared with Chemo, Io+Chemo induced higher rates of pathological complete response (33.3 vs. 9.2%, p=0.001) and major pathological response (MPR) (49.2 vs. 30.8%, p=0.033). …”
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Development and characterization of a chicory extract fermented by Akkermansia muciniphila: An in vitro study on its potential to modulate obesity-related inflammation by A. Chervet, R. Nehme, C. Defois-Fraysse, C. Decombat, C. Blavignac, C. Auxenfans, B. Evrard, S. Michel, E. Filaire, J.-Y. Berthon, A. Dreux-Zigha, L. Delort, F. Caldefie-Chézet

“…We found that C-Akm extract decreased ROS generation, TNF-α and Il-6 gene expression in polarized macrophages, INFγ and IL-17A secretion in LPS-stimulated PBMCs stimulated with LPS. …”
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Expression of LAIR-1 (CD305) on Human Blood Monocytes as a Marker of Hepatic Cirrhosis Progression by María Martínez-Esparza, Antonio José Ruiz-Alcaraz, Violeta Carmona-Martínez, María Dolores Fernández-Fernández, Gonzalo Antón, María Muñoz-Tornero, Miriam Lencina, Inmaculada Pagán, Jesús de la Peña, Pilar García-Peñarrubia

“…We studied the LAIR-1 expression on liver macrophages and blood monocytes related to the progression of liver cirrhosis. …”
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Single-cell transcriptomics reveals the heterogeneity and function of mast cells in human ccRCC by Xiyu Song, Xiyu Song, Xiyu Song, Jianhua Jiao, Jianhua Jiao, Jiayang Qin, Wei Zhang, Weijun Qin, Weijun Qin, Shuaijun Ma, Shuaijun Ma

“…Furthermore, the highest level of IL1B expression was observed in macrophages in ccRCC samples, and spatial transcriptome analysis revealed the colocalization of VEGFA+ MCs with IL1B+ macrophages at the tumor–normal interface.DiscussionIn conclusion, this study revealed increased MC density in ccRCC. …”
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Integrating single-cell RNA-seq and bulk RNA-seq to explore prognostic value and immune landscapes of methionine metabolism-related signature in breast cancer by Yanxian Gao, Ziyu Feng, Hailong Zhao, Xinghai Liu, Muyu Zhu, Xiafei Yu, Xiaoan Liu, Xian Wu, Jing Tao

“…The function of APOC1 in regulating macrophage polarization was explored.…”
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Inflammatory changes in the choroid plexus following subarachnoid hemorrhage: the role of innate immune receptors and inflammatory molecules by Peter Solár, Peter Solár, Václav Brázda, Václav Brázda, Martin Bareš, Alemeh Zamani, Parisa EmamiAref, Andrea Joukal, Lucie Kubíčková, Erik Kročka, Klaudia Hašanová, Marek Joukal

“…These pro-inflammatory changes include accumulation in the choroid plexus of pro-inflammatory cytokines, innate immune receptors, and monocyte-derived macrophages.…”
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Th1 and Th17 Cells in Tuberculosis: Protection, Pathology, and Biomarkers by I. V. Lyadova, A. V. Panteleev

“…Th1 cells have been shown to contribute to TB protection by secreting IFN-γ and activating antimycobacterial action in macrophages. Th17 induce neutrophilic inflammation, mediate tissue damage, and thus have been implicated in TB pathology. …”
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Role of Inflammatory Cell Subtypes in Heart Failure by Derek Strassheim, Edward C. Dempsey, Evgenia Gerasimovskaya, Kurt Stenmark, Vijaya Karoor

“…Various types of immune cells are implicated in myocardial inflammation and include neutrophils, macrophages, eosinophils, mast cells, natural killer cells, T cells, and B cells. …”
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Contribution of Gut Bacteria to Liver Pathobiology by Gakuhei Son, Michael Kremer, Ian N. Hines

“…Receiving approximately 70% of its blood supply from the intestinal venous outflow, the liver represents the first line of defense against gut-derived antigens and is equipped with a broad array of immune cells (i.e., macrophages, lymphocytes, natural killer cells, and dendritic cells) to accomplish this function. …”
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