Hepatoma cell-derived exosomal SNORD52 mediates M2 macrophage polarization by activating the JAK2/STAT6 pathway by Yaqiong Zhang, Bo Li, Wanhong Gu, Linna Fan, Xiaofan Wang, Meifen Xu, Minqi Zhu, Chong Jin

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Tp53 determines the spatial dynamics of M1/M2 tumor-associated macrophages and M1-driven tumoricidal effects by Yi-Jing Hsiao, Min-Shu Hsieh, Gee-Chen Chang, Yin-Chen Hsu, Chia-Yu Wang, Yan-Ming Chen, Yi-Ling Chen, Pan-Chyr Yang, Sung-Liang Yu

“…Abstract The spatial role of M1 and M2 tumor-associated macrophages (M1/M2 TAMs) in precision medicine remains unclear. …”
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GP73-mediated secretion of PKM2 and GP73 promotes angiogenesis and M2-like macrophage polarization in hepatocellular carcinoma by Shujie Wang, Tongjia Zhang, Yue Zhou, Zitao Jiao, Kejia Lu, Xinyi Liu, Wei Jiang, Zhe Yang, Hui Li, Xiaowei Zhang

“…Extracellular PKM2 and GP73 synergistically promoted angiogenesis and polarization of M2-type macrophages, thereby leading to malignant progression and sorafenib resistance in HCC. …”
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Ablation of the deubiquitinating enzyme cylindromatosis (CYLD) augments STAT1-mediated M1 macrophage polarization and fosters Staphylococcus aureus control by Christina Schmidt, Kunjan Harit, Stephan Traidl, Michael Naumann, Thomas Werfel, Thomas Werfel, Lennart M. Roesner, Lennart M. Roesner, Gopala Nishanth, Dirk Schlüter, Dirk Schlüter

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The injury effect of osteopontin in sepsis-associated lung injury by Qian Wang, Zhicai Yu, Zhixin Song, Xue Lu, Zhu Li, Dandan Pi, Jing Li, Feng Xu

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Prediction of ADMET profile and anti-inflammatory potential of chamuangone by Sompot Jantarawong, Puripat Wathanaphanit, Pharkphoom Panichayupakaranant, Yutthana Pengjam

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The immune landscape of fetal chorionic villous tissue in term placenta by Brianna M. Doratt, Heather E. True, Heather E. True, Suhas Sureshchandra, Suhas Sureshchandra, Qi Qiao, Qi Qiao, Monica Rincon, Nicole E. Marshall, Ilhem Messaoudi

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Rap1 and mTOR signaling pathways drive opposing immunotoxic effects of structurally similar aryl-OPFRs, TPHP and TOCP by Bilin Zhao, Shuang Zheng, Gaoxiang Yang, Zhijun He, Jiewei Deng, Lijuan Luo, Xinyan Li, Tiangang Luan

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The Autoimmune Profiles in the Etiopathogenesis of Granulomatous Lobular Mastitis by Lu Xie, Jiamei Feng, Qingqian Gao, Wenchao Qu, Shijun Shao, Jiaye Sun, Xueqing Wu, Hua Wan

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CD44-Receptors-Mediated Multiprong Targeting Strategy Against Breast Cancer and Tumor-Associated Macrophages: Design, Optimization, Characterization, and Cytologic Evaluation by Hussain Z, Abdulrahim Abdul Moti L, Jagal J, Thu HE, Khan S, Kazi M

“…In this research, we aimed to design a multiprong targeting strategy for concurrent action against different phenotypes of BC (MCF-7 and SK-BR-3) and tumor-associated macrophages (TAMs) for relapse-free treatment of BC.Methods: Paclitaxel (PTX) and tamoxifen (TMX) co-loaded chitosan (CS) nanoparticles (NPs) were prepared using the ionic-gelation method and optimized using the Design Expert® software by controlling different material attributes. …”
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Inhibition of RAC1 activator DOCK2 ameliorates cholestatic liver injury via regulating macrophage polarisation and hepatic stellate cell activation by Jianli Qiu, Yitong Qu, Yinli Li, Cancan Li, Junling Wang, Lu Meng, Xiaojin Jing, Jiangping Fu, Yan Xu, Yuna Chai

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Q11, a CYP2E1 inhibitor, exerts anti-hepatocellular carcinoma effect by inhibiting M2 macrophage polarization by Cunzhen Zhang, Yan Fang, Mengxue Guo, Liming Tang, Yurong Xing, Jun Zhou, Yuanyuan Guo, Yuhan Gu, Qiang Wen, Na Gao, Haiwei Xu, Hailing Qiao

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β-receptor blocker enhances anti-tumor immunity via inhibiting lactate-induced norepinephrine metabolism of macrophages during malignant pleural effusion by Ru Zhang, Weijia Wang, Aitian Li, Huishang Wang, Xiaoyan Liu, Feifei Fan, Ying Wang, Huanyu Zhang, Jingxia Chang, Yinyin Zhang, Hongmin Wang, Lijun Miao, Bo Huang, Li Yang, Li Yang, Li Yang, Yi Zhang, Yi Zhang, Yi Zhang, Yi Zhang, Yi Zhang

Subjects: “…macrophage…”
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Involvement of Proteasome and Macrophages M2 in the Protection Afforded by Telmisartan against the Acute Myocardial Infarction in Zucker Diabetic Fatty Rats with Metabolic Syndrome by C. Di Filippo, C. Rossi, B. Ferraro, R. Maisto, A. De Angelis, F. Ferraraccio, A. Rotondo, M. D’Amico

“…This study investigated the involvement of proteasome and macrophages M2 in the protection afforded by telmisartan against the acute myocardial infarction in Zucker diabetic fatty (ZDF) rats with metabolic syndrome. …”
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cAMP analogues downregulate the expression of granulocyte macrophage colony-stimulating factor (GM-CSF) in human bone marrow stromal cells in vitro by G. Bug, J. Aman, C. Huber, C. Peschel, H. G. Derigs

“…The stimulation of granulocyte macrophage-colony stimulating factor (GM-CSF) by interleukin-1 (IL-1) has been shown to be counteracted in different mesenchymal cell systems by cyclic adenosine monophosphate (cAMP) agonists. …”
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Liposome-Encapsulated Bioactive Guttiferone E Exhibits Anti-Inflammatory Effect in Lipopolysaccharide-Stimulated MH-S Macrophages and Cytotoxicity against Human Cancer Cells by Jean Paul Dzoyem, Shashank Reddy Pinnapireddy, Hugues Fouotsa, Jana Brüßler, Frank Runkel, Udo Bakowsky

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Macrophages facilitate tumor cell PD‐L1 expression via an IL‐1β‐centered loop to attenuate immune checkpoint blockade by Cheng Xu, Yu Xia, Bai‐Wei Zhang, Emmanuel Kwateng Drokow, Hua‐Yi Li, Sen Xu, Zhen Wang, Si‐Yuan Wang, Ping Jin, Tian Fang, Xiao‐Ming Xiong, Pu Huang, Ning Jin, Jia‐Hong Tan, Qing Zhong, Yu‐Xin Chen, Qi Zhang, Yong Fang, Fei Ye, Qing‐Lei Gao

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GAMG alleviates liver fibrosis through inducing ferroptosis in inflammatory macrophages via the IRF1/SLC7A11 signaling pathway by Qing Pang, Shuai Zhou, Yong Wang, Hongtao Pan, Zhixin Wang, Xilaing Qin, Chao Zhu, Shilei Chen, Huichun Liu, Xiaosi Hu, Hao Jin

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Altered Macrophage and Dendritic Cell Response in Mif−/− Mice Reveals a Role of Mif for Inflammatory-Th1 Response in Type 1 Diabetes by Yuriko Itzel Sánchez-Zamora, Imelda Juarez-Avelar, Alicia Vazquez-Mendoza, Marcia Hiriart, Miriam Rodriguez-Sosa

“…Macrophage migration inhibitory factor (Mif) is highly expressed in type 1 diabetes mellitus (T1DM). …”
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Protective Effect of Sex Hormone-Binding Globulin against Metabolic Syndrome: In Vitro Evidence Showing Anti-Inflammatory and Lipolytic Effects on Adipocytes and Macrophages by Hiroki Yamazaki, Akifumi Kushiyama, Hideyuki Sakoda, Midori Fujishiro, Takeshi Yamamotoya, Yusuke Nakatsu, Takako Kikuchi, Sunao Kaneko, Hirotoshi Tanaka, Tomoichiro Asano

“…In this study, using adipocytes and macrophages, we focused on the in vitro effects of SHBG on inflammation as well as lipid metabolism. …”
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