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Ferroptosis in Macrophage Impairment in Sepsis
Published 2022-01-01“…Regulating the function of macrophages may be a potential method for the treatment of sepsis. …”
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Macrophage Heterogeneity in Respiratory Diseases
Published 2013-01-01“…Macrophages are among the most abundant cells in the respiratory tract, and they can have strikingly different phenotypes within this environment. …”
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PPARs in Alveolar Macrophage Biology
Published 2007-01-01“…PPARs, most notably PPAR-γ, play a crucial role in regulating the activation of alveolar macrophages, which in turn occupy a pivotal place in the immune response to pathogens and particulates drawn in with inspired air. …”
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Macrophage Polarisation in the Tumour Microenvironment: Recent Research Advances and Therapeutic Potential of Different Macrophage Reprogramming
Published 2025-01-01“…In the tumour microenvironment, however, macrophages are often reprogrammed into tumour-associated macrophages (TAMs), which promote tumour growth, metastasis, and therapeutic resistance. …”
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Transcriptional analysis of murine biliary atresia identifies macrophage heterogeneity and subset-specific macrophage functions
Published 2025-01-01Subjects: Get full text
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Characteristics of Suppressor Macrophages Induced by Mycobacterial and Protozoal Infections in relation to Alternatively Activated M2 Macrophages
Published 2012-01-01“…In the advanced stages of mycobacterial infections, host immune systems tend to change from a Th1-type to Th2-type immune response, resulting in the abrogation of Th1 cell- and macrophage-mediated antimicrobial host protective immunity. …”
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The Evolving Roles of Macrophages in Organ Transplantation
Published 2019-01-01“…However, emerging evidence suggests macrophages as crucial mediators of acute and chronic allograft immunopathology. …”
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Role of macrophage in intervertebral disc degeneration
Published 2025-01-01“…To gain a deeper understanding of the inflammatory microenvironment of intervertebral disc degeneration, this review will summarize the role of macrophages in the pathological process of intervertebral disc degeneration, analyze the regulatory mechanisms involving macrophages, and review therapeutic strategies targeting macrophage modulation for the treatment of intervertebral disc degeneration. …”
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Macrophage-Based Therapies for Atherosclerosis Management
Published 2020-01-01“…In this review, we focused on the systematical summary of the macrophage-based therapies in AS management, including macrophage autophagy, polarization, targeted delivery, microenvironment-triggered drug release, and macrophage- or macrophage membrane-based drug carrier. …”
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The Role of Macrophages in the Pathogenesis of Celiac Disease
Published 2024-10-01Subjects: Get full text
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Role of Macrophages in the Pathogenesis of Atopic Dermatitis
Published 2013-01-01“…In AD, macrophages are known to accumulate in acutely and chronically inflamed skin. …”
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Macrophages in Tumor Microenvironments and the Progression of Tumors
Published 2012-01-01“…Two distinct subsets of macrophages have been proposed, including classically activated (M1) and alternatively activated (M2) macrophages. …”
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Iron Reduces M1 Macrophage Polarization in RAW264.7 Macrophages Associated with Inhibition of STAT1
Published 2017-01-01“…Iron metabolism in inflammation has been mostly characterized in macrophages exposed to pathogens or inflammatory conditions. …”
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Macrophage-derived neutrophil chemotactic factor is involved in the neutrophil recruitment inhibitory activity present in the supernatants of LPS-stimulated macrophages
Published 1996-01-01“…In a previous study, we demonstrated the presence of a neutrophil recruitment inhibitory factor (NRIF) in the supernatants of LPS-stimulated macrophages. Recently, the purification of a 54 kDa protein, identified as the macrophage-derived neutrophil chemotactic factor (MNCF) was reported. …”
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FXR activation reduces the formation of macrophage foam cells and atherosclerotic plaque, possibly by down regulating hepatic lipase in macrophages
Published 2025-02-01Subjects: Get full text
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Macrophage Migration Inhibitory Factor in Protozoan Infections
Published 2012-01-01“…Macrophage migration inhibitory factor (MIF) is a cytokine that plays a central role in immune and inflammatory responses. …”
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Autophagy in Macrophages: Impacting Inflammation and Bacterial Infection
Published 2014-01-01“…This review focuses on the intimately linked molecular mechanisms that help govern the autophagic pathway and macrophage innate immune responses.…”
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Dysregulated Functions of Lung Macrophage Populations in COPD
Published 2018-01-01“…In addition, we discuss the differences in the responses between alveolar macrophages and interstitial macrophages/monocytes in the disease and propose how the field should advance to better understand the implications of lung macrophage functions in COPD.…”
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