Nonylphenol exposure increases the risk of Hirschsprung’s disease by inducing macrophage M1 polarization by Xuefeng Yang, Chengyan Tang, Daiwei Zhu, Xingrong Xia, Qing Du, Lu Huang, Jianguo Liu, Yuanmei Liu

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The injectable hydrogel loading cannabidiol to regulate macrophage polarization in vitro for the treatment of chronic enteritis by Ye Wang, Xingming Ji, Xinyi Wang, Mengyu Sun, Cheng Li, Dongmei Wu

“…Results: Our study found that GelMA + CBD with biosafety, could make CBD be slowly released, and effectively inhibit the M1-type polarization of macrophages in vitro, and promote the M2-type polarization. …”
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Human placental extract improves liver cirrhosis in mice with regulation of macrophages and senescent cells by Natsuki Ishikawa, Yusuke Watanabe, Yuichirou Maeda, Tomoaki Yoshida, Naruhiro Kimura, Hiroyuki Abe, Akira Sakamaki, Hiroteru Kamimura, Takeshi Yokoo, Kenya Kamimura, Atsunori Tsuchiya, Shuji Terai

“…The results showed that HPE strongly polarized macrophages to the M2 phenotype, especially in macrophage-rich regions in the liver. …”
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Antibodies directed to antigens secreted by murine epithelioid macrophages modulate BCG-induced granulomata by Mario Mariano, Tania Aguiar, Celia R. W. Carneiro, Edilberto Postol, Venânclo A. F. Alves, Ricardo Ribeiro-dos-Santos

“…The authors have previously shown that epithelioid cells isolated from mice secrete a factor, called macrophage deactivating factor (MDF), that promptly deactivates superoxide release by activated macrophages and neutrophils. …”
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FDFT1 inhibits macrophage M1 polarization and promotes colorectal cancer progression by GAO Yuan, HUANG Yulan, ZHAO Kun

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Lancemaside A from Codonopsis lanceolata Modulates the Inflammatory Responses Mediated by Monocytes and Macrophages by Eunji Kim, Woo Seok Yang, Ji Hye Kim, Jae Gwang Park, Han Gyung Kim, Jaeyoung Ko, Yong Deog Hong, Ho Sik Rho, Song Seok Shin, Gi-Ho Sung, Jae Youl Cho

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Oxidized Lipoproteins Suppress Nitric Oxide Synthase in Macrophages: Study of Glucocorticoid Receptor Involvement by K. E. Matthys, P. G. Jorens, B. Marescau, M. Rosseneu, H. Bult, A. G. Herman

“…Activated cholesterol-laden macrophages in atherosclerotic lesions are believed to influence the progression of this disease. …”
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Electroacupuncture Regulates Macrophage Polarization to Alleviate the Neuropathic Pain Induced by Spared Nerve Injury by Shi G, Hao X, Tu JF, Chen W, Fu Y, Ma X, Liu C, Li H

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Auriculotherapy Modulates Macrophage Polarization to Reduce Inflammatory Response in a Rat Model of Acne by Guang Zuo, Yidan Gao, Guangtong Lu, Ming Bu, Jun Liu, Juncha Zhang, Xisheng Fan, Hao Chen, Xuesong Wang, Yanfen She

“…Meanwhile, the three interventions reduced M1-type macrophages and increased M2-type macrophages; only APS could reduce the expression of TLR2/NF-κB signaling pathway. …”
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Identification of Differentially Expressed lncRNAs in a CpG ODN-Activated Macrophage by Ying Zheng, Xi Luo, Zailong Qin, Zhiguang Zhou

“…A macrophage is an important component of innate immunity which can be activated by infection. …”
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Effects of natural products on macrophage immunometabolism: A new frontier in the treatment of metabolic diseases by Jiani Li, Chen Guo, Xiaofei Yang, Weinan Xie, Wenjing Mi, Chenglong Hua, Cheng Tang, Han Wang

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Characterization of Macrophage Phenotypes in Three Murine Models of House-Dust-Mite-Induced Asthma by Christina Draijer, Patricia Robbe, Carian E. Boorsma, Machteld N. Hylkema, Barbro N. Melgert

“…Key innate immune cells in the lungs are macrophages. Depending on the signals they receive, macrophages can at least have an M1, M2, or M2-like phenotype. …”
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Comparative Evaluation of Permissiveness to Dengue Virus Serotype 2 Infection in Primary Rodent Macrophages by Jeanette Prada-Arismendy, Verónica Rincón, Jaime E. Castellanos

“…This work evaluated the in vitro permissiveness of mouse, rat, hamster and guinea pig macrophages to infection by dengue virus 2 (DENV2). …”
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α-Synuclein fibrils enhance HIV-1 infection of human T cells, macrophages and microglia by Lia-Raluca Olari, Sichen Liu, Franziska Arnold, Julia Kühlwein, Marta Gil Miró, Ajeet Rijal Updahaya, Christina Stürzel, Dietmar Rudolf Thal, Paul Walther, Konstantin M. J. Sparrer, Karin M. Danzer, Jan Münch, Frank Kirchhoff

“…Here, we show that α-synuclein and (to a lesser extent) Aβ fibrils associated with neurological diseases enhance HIV-1 entry and replication in human T cells, macrophages, and microglia. Additionally, an HIV-1 Env-derived amyloidogenic peptide accelerated amyloid formation by α-synuclein and Aβ peptides. …”
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A thorny pathway of macrophage activating factor (GcMAF): from bench to bedside by A. A. Ostanin, S. S. Kirikovich, E. V. Dolgova, А. S. Proskurina, E. R. Chernykh, S. S. Bogachev

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Androgen metabolism and inhibition of interleukin-1 synthesis in primary cultured human synovial macrophages by M. Cutolo, S. Accardo, B. Villaggio, A. Barone, A. Sulli, E. Balleari, C. Bason, L. Felli, O. M. Granata, R. Amodio, L. Castagnetta

“…The presence of androgen receptors on synovial macrophages in human normal and rheumatoid synovial tissues has been described previously. …”
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ADAM-10 Regulates MMP-12 during Lipopolysaccharide-Induced Inflammatory Response in Macrophages by Yan Jiang, Qiming Gong, Jinmei Huang, Yuanxun Gong, Qiang Tang, Dalong Wei, Qianli Tang, Jingjie Zhao, Jian Song, Lingzhang Meng

“…In this study, we investigated the regulatory mechanism of ADAM-10 in the lipopolysaccharide-promoted proliferation (LPS) of the macrophage inflammatory response. Differentially expressed or regulated proteins were identified in interfered ADAM-10 (sh ADAM-10) macrophages using tandem mass tag (TMT) proteomics. …”
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Identification and Functional Analysis of EPOR+ Tumor-Associated Macrophages in Human Osteosarcoma Lung Metastasis by Yanxing Li, Ming Li, Rong Wei, Junlong Wu

“…Background. Tissue-resident macrophages can be educated to tumor-associated macrophages (TAMs) by the tumor microenvironment and many types of macrophages express erythropoietic receptor (EPOR); However, little is known about the expression of EPOR on TAMs and the identity of EPOR+ TAMs in osteosarcoma lung metastasis has thus far remained elusive. …”
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The injury effect of osteopontin in sepsis-associated lung injury by Qian Wang, Zhicai Yu, Zhixin Song, Xue Lu, Zhu Li, Dandan Pi, Jing Li, Feng Xu

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Prediction of ADMET profile and anti-inflammatory potential of chamuangone by Sompot Jantarawong, Puripat Wathanaphanit, Pharkphoom Panichayupakaranant, Yutthana Pengjam

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