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1581
Uridine-cytidine kinase 2 is correlated with immune, DNA damage repair and promotion of cancer stemness in pan-cancer
Published 2025-01-01“…There were significant correlations between UCK2 and T cells, monocytes, mast cells, and macrophages. Moreover, as expected, the immune checkpoint human leucocyte antigen (HLA) was found to be negatively related to UCK2. …”
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1582
Systemic and mammary inflammation and mammary gland development of Holstein dairy cows around dry-off and calving
Published 2025-02-01“…Mammary tissues collected in the early dry period had greater percentages of CD20+ B lymphocytes, CD172a+ macrophages, and neutrophils than tissues collected during late lactation. …”
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1583
LANCL1 as the Key Immune Marker in Neuropathic Pain
Published 2022-01-01“…Cascade reactions including mast cells, macrophages, and T cells may be an important reason for the aggravation of nerve damage.…”
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1584
Tracking Tumor Cells in Lymphatics in a Mice Xenograft Model by Magnetic Resonance Imaging
Published 2012-11-01“…Histologic findings confirmed the in vivo MRI results and revealed lymphangiogenesis, angiogenesis, infiltration of macrophages, and expression of vascular endothelial growth factor C in tumor and draining lymph nodes as well. …”
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1585
Innate Immune Response in Kidney Ischemia/Reperfusion Injury: Potential Target for Therapy
Published 2017-01-01“…This innate immune response is characterized by the activity of classical cells belonging to the immune system, such as neutrophils, macrophages, dendritic cells, lymphocytes, and also tubular epithelial cells and endothelial cells. …”
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1586
Therapeutic implications for the PD-1 axis in cerebrovascular injury
Published 2025-01-01“…In myeloid cells, PD-1 stimulation induces polarization of microglia and macrophages into an anti-inflammatory, restorative phenotype. …”
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1587
Androgen receptor dynamics in prostate cancer: from disease progression to treatment resistance
Published 2025-02-01“…The tumor microenvironment, particularly interactions with cancer-associated fibroblasts (CAFs) and tumor-associated macrophages (TAMs), further complicates treatment by promoting aggressive tumor behavior and immune evasion. …”
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1588
Significance of Hyperreflective Foci as an Optical Coherence Tomography Biomarker in Retinal Diseases: Characterization and Clinical Implications
Published 2021-01-01“…Histopathological correlates of HRF are not univocal, spacing from migrating retinal pigment epithelium cells, lipid-laden macrophages, microglial cells, and extravasated proteinaceous or lipid material. …”
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1589
Case of the Diffuse Form of Xanthogranulomatous Pyelonephritis
Published 2013-01-01“…Microscopic findings of the left kidney revealed infiltration of lymphocytes and lipid-laden macrophages (xanthoma cells) corresponding to XGP.…”
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1590
Ratio Imaging of Enzyme Activity Using Dual Wavelength Optical Reporters
Published 2002-04-01“…Using mixtures of the two probes, we have shown that the ratio of Cy5.5 to Cy3.5 fluorescence can be used to determine levels of cathepsin B in the environment of nanoparticles with macrophages in suspension. After intravenous injection, tissue fluorescence from the nondegradable Cy3.5– d -arginyl probe reflected nanoparticle accumulation, while fluorescence of the Cy5.5– l -arginyl probe was dependent on both accumulation and activation by cathepsin B. …”
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1591
Exosome-Derived microRNA: Potential Target for Diagnosis and Treatment of Sepsis
Published 2024-01-01“…This review comprehensively explores the biology of exosome-derived miRNAs, which originate from both immune cells (such as macrophages and dendritic cells) and nonimmune cells (such as endothelial and epithelial cells) and play a dynamic role in modulating pathways that affect the course of sepsis, including those related to inflammation, immune response, cell survival, and apoptosis. …”
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1592
Molecular and Cellular Pathways Contributing to Joint Damage in Rheumatoid Arthritis
Published 2020-01-01“…Although etiology of this disease is not clear, several immune pathways, involving immune (T cells, B cells, dendritic cells, macrophages, and neutrophils) and nonimmune (fibroblasts and chondrocytes) cells, participate in the secretion of many proinflammatory cytokines, chemokines, proteases (MMPs, ADAMTS), and other matrix lysing enzymes that could disturb the immune balance leading to cartilage and bone damage. …”
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1593
NF-κB signaling and the tumor microenvironment in osteosarcoma: implications for immune evasion and therapeutic resistance
Published 2025-01-01“…This research aimed to explore how NF-κB influences the recruitment and polarization of tumor-associated macrophages and myeloid-derived suppressor cells, both of which contribute to immunosuppression. …”
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1594
Metastatic Calcinosis of Aortic Valve Secondary to Renal Failure Mimicking Infective Endocarditis
Published 2016-01-01“…Later on, biopsy of her hand lesions showed extensive calcification with macrophages and giant cells. No atypia or malignancy was identified. …”
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1595
Inflammation in Diabetic Nephropathy
Published 2012-01-01“…We highlight the important role of inflammatory cells in the kidney, particularly infiltrating macrophages, T-lymphocytes and the subpopulation of regulatory T cells. …”
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1596
Total synthesis and target identification of marine cyclopiane diterpenes
Published 2024-12-01“…Preliminary mechanism of action studies shows that conidiogenone C activates IRGM1-mediate dysfunctional mitochondria autophagy to maintain mitochondria quality control of inflammatory macrophages.…”
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1597
Ways to promote the efficiency of herpetic stomatitis treatment
Published 2023-06-01“…The drug suppresses the synthesis of the virus due to the structure of inosinic acid in the polyribosomes of the cell affected by the virus, and also helps to eliminate the deficiency or dysfunction of immunity that occurred in the case of herpetic stomatitis, it affects the activity of T-cytotoxic lymphocytes and natural killers, enhances the action of neutrophil granulocytes, chemotaxis and phagocytosis of monocytes and macrophages, increases the synthesis of interleukins IL-1 and IL-2, affects the number of Ig G immunoglobulins. …”
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1598
Impact of Thrombopoietin Receptor Agonists on Pathophysiology of Pediatric Immune Thrombocytopenia
Published 2025-01-01“…Various pathophysiological mechanisms are implicated in ITP pathogenesis, including the production of autoantibodies against components of platelets (PLTs) by B-cells, the activation of the complement system, phagocytosis by macrophages mediated by Fcγ receptors, the dysregulation of T cells, and reduced bone marrow megakaryopoiesis. …”
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1599
The TIR Domain Containing Locus of Enterococcus faecalis Is Predominant among Urinary Tract Infection Isolates and Downregulates Host Inflammatory Response
Published 2014-01-01“…Infection of mouse RAW264.7 macrophages with a tcpF knock-out mutant led to elevated cytokine response compared to the isogenic wild type E. faecalis strain. …”
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1600
Gemistocytic tumor cells programmed for glial scarring characterize T cell confinement in IDH-mutant astrocytoma
Published 2025-01-01“…Integrative analysis shows that GTC-high tumors are enriched for lymphocytes and tumor associated macrophages (TAM) and express immune cell migration and activation programs. …”
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