Macrophage Extracellular Traps: Current Opinions and the State of Research regarding Various Diseases by Weizhen Weng, Zuoyu Hu, Yunfeng Pan

“…Some studies found that macrophages can produce extracellular traps (ETs) under various conditions of stimulation. …”
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Moesin integrates cortical and lamellar actin networks during Drosophila macrophage migration by Besaiz J. Sánchez-Sánchez, Stefania Marcotti, David Salvador-Garcia, María-del-Carmen Díaz-de-la-Loza, Mubarik Burki, Andrew J. Davidson, Will Wood, Brian M. Stramer

“…Here we exploit Drosophila macrophage (hemocyte) developmental dispersal to reveal that these cells maintain both a lamellar actin network at their cell front and a cortical actin network at the rear. …”
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PGC-1α activation to enhance macrophage immune function in mycobacterial infections. by Joel R Frandsen, Zhihong Yuan, Brahmchetna Bedi, Zohra Prasla, Seoung-Ryoung Choi, Prabagaran Narayanasamy, Ruxana T Sadikot

“…Both PGC-1α and TFAM regulate mitochondrial biogenesis and activity, and their disruption is linked to inflammatory signaling and altered macrophage function. We show that NTM causes macrophage mitochondrial damage and disrupted bioenergetics. …”
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HMGB1 Promotes Systemic Lupus Erythematosus by Enhancing Macrophage Inflammatory Response by Mudan Lu, Shanshan Yu, Wei Xu, Bo Gao, Sidong Xiong

“…Further study demonstrated that increased HMGB1 expression deteriorated the severity of SLE via enhancing macrophage inflammatory response. Moreover, we found that receptor of advanced glycation end products played a critical role in HMGB1-mediated macrophage inflammatory response. …”
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The role of natural products targeting macrophage polarization in sepsis-induced lung injury by Yake Li, Sinan Ai, Yuan Li, Wangyu Ye, Rui Li, Xiaolong Xu, Qingquan Liu

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Bioluminescence and Magnetic Resonance Imaging of Macrophage Homing to Experimental Abdominal Aortic Aneurysms by Noriyuki Miyama, Monica M. Dua, Geoffrey M. Schultz, Hisanori Kosuge, Masahiro Terashima, Laura J. Pisani, Ronald L. Dalman, Michael V. McConnell

“…Macrophage infiltration is a prominent feature of abdominal aortic aneurysm (AAA) progression. …”
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Vaginal Microbial Environment Skews Macrophage Polarization and Contributes to Cervical Cancer Development by Guannan Zhou, Fangyue Zhou, Yuanyuan Gu, Menglei Zhang, Ganrong Zhang, Fang Shen, Keqin Hua, Jingxin Ding

“…The tube formation assay disclosed the function of Peptostreptococcus anaerobius-treated macrophages on angiogenesis. In vivo assays were also established to explore the impact of Peptostreptococcus anaerobius-treated macrophages on tumor migration. …”
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The Role of T Cells and Macrophages in Asthma Pathogenesis: A New Perspective on Mutual Crosstalk by Xueyi Zhu, Jie Cui, La Yi, Jingjing Qin, Wuniqiemu Tulake, Fangzhou Teng, Weifeng Tang, Ying Wei, Jingcheng Dong

“…Asthma is associated with innate and adaptive immunity mediated by immune cells. T cell or macrophage dysfunction plays a particularly significant role in asthma pathogenesis. …”
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Nanoporosity of Alumina Surfaces Induces Different Patterns of Activation in Adhering Monocytes/Macrophages by Natalia Ferraz, Jaan Hong, Matteo Santin, Marjam Karlsson Ott

“…The present study shows that alumina nanotopography affects monocyte/macrophage behavior. Human mononuclear cells cultured on alumina membranes with pore diameters of 20 and 200 nm were evaluated in terms of cell adhesion, viability, morphology, and release of proinflammatory cytokines. …”
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Profiling the Resident and Infiltrating Monocyte/Macrophages during Rejection following Kidney Transplantation by Jie Wang, Peiling Luo, Jingjie Zhao, Junhua Tan, Feifan Huang, Ruiying Ma, Peng Huang, Meiying Huang, Yuming Huang, Qiuju Wei, Liuzhi Wei, Zechen Wang, Lingzhang Meng

“…By conducting a single-cell RNA analysis, the type and status of monocyte/macrophages in kidney transplantation were described, in which monocyte/macrophages were observed to form two different subpopulations: resident and infiltrating monocyte/macrophages. …”
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Increased Expression of Visfatin in Monocytes and Macrophages in Male Acute Myocardial Infarction Patients by Cheng-An Chiu, Teng-Hung Yu, Wei-Chin Hung, Li-Fen Lu, Fu-Mei Chung, I-Ting Tsai, Chih-Ying Yang, Chia-Chang Hsu, Yung-Chuan Lu, Jer-Yiing Houng, Yau-Jiunn Lee, Chao-Ping Wang

“…Furthermore, visfatin was strongly appeared in lipid rich coronary rupture plaques and macrophages. These results suggest another explanation about leukocytes mediated visfatin that may play a pathogenesis role in coronary vulnerable plaques rupture.…”
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Pathogenic Roles of Macrophage Migration Inhibitory Factor during Dengue Virus Infection by Yung-Chun Chuang, Hong-Ru Chen, Trai-Ming Yeh

“…In this review, we focus on the possible pathogenic effects of a pleiotropic cytokine, macrophage migration inhibitory factor (MIF), on the pathogenesis of DENV infection. …”
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Effect of dual targeting procyanidins nanoparticles on metabolomics of lipopolysaccharide-stimulated inflammatory macrophages by Shanshan Tie, Lijuan Zhang, Bin Li, Shanghua Xing, Haitao Wang, Yannan Chen, Weina Cui, Shaobin Gu, Mingqian Tan

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Secretome of polarized macrophages: potential for targeting inflammatory dynamics in spinal cord injury by Andreia Monteiro, Susana Monteiro, Nuno A. Silva

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Macrophage-derived extracellular vesicles as new players in chronic non-communicable diseases by Fengjuan Lin, Huiyu Luo, Jiexian Wang, Qing Li, Longying Zha

Subjects: “…macrophage-derived extracellular vesicles…”
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Polydatin retards the progression of osteoarthritis by maintaining bone metabolicbalance and inhibiting macrophage polarization by Qi Sun, Xin-Yu Nan, Hui Wang, Shuo Pan, Gang Ji, Ya-Feng Guo, Ya-Heng Zhao, Gao-Cen Li, Shao-Shi Guo, Lu-Feng Lin, Yu-Jie Jin, Xue Li Zhang, Chang-Cheng Liu, Guo-Bin Liu

“…In addition, paeoniflorin markedly suppresses the transmission of the NF-κB signaling pathway and reverses M1 polarization in macrophages induced by IL-1β.ConclusionTaken together, PD might be a potential therapeutic agent for the prevention and treatment of osteoarthritis.…”
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HIF1α-Induced Glycolysis Metabolism Is Essential to the Activation of Inflammatory Macrophages by Ting Wang, Huiying Liu, Guan Lian, Song-Yang Zhang, Xian Wang, Changtao Jiang

“…Previous studies have demonstrated that HIF1α participates in the M1 polarization of macrophages. To clarify the mechanism of HIF1α-induced polarization of M1 macrophage, myeloid-specific HIF1α overexpression (Lysm HIF1α lsl) mice were employed and the bone marrow-derived and peritoneal macrophages were isolated. …”
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Nanocarriers and macrophage interaction: from a potential hurdle to an alternative therapeutic strategy by Naths Grazia Sukubo, Paolo Bigini, Annalisa Morelli

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Mesenchymal Stem Cell-Educated Macrophages Ameliorate LPS-Induced Systemic Response by Yaoqin Hu, Chaojin Qin, Guoping Zheng, Dengming Lai, Huikang Tao, Yan Zhang, Guanguan Qiu, Menghua Ge, Lanfang Huang, Lina Chen, Baoli Cheng, Qiang Shu, Jianguo Xu

“…Mouse peritoneal macrophages were cocultured with ASCs in a Transwell system for 2 days to educate macrophages. …”
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Effects of esculentoside A on turnour necrosis factor production by mice peritoneal macrophages by Fang Jun, Zheng Qin Yue, Wang Hong Bin, Ju Dian Wen, Yi Yang Hua

“…In order to study the mechanism of the anti-inflammatory effect of EsA, it was determined whether TNF production from macrophages was altered by EsA under lipopolysaccharide (LPS) stimulated conditions. …”
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