Reduction of nitric oxide release from alveolar macrophages by a lipocortin peptide by A. M. Kamal, T. D. Tetley, I. R. Witherden, S. F. Smith

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Macrophage-inherited exosome excise tumor immunosuppression to expedite immune-activated ferroptosis by Yan Liu, Junjie Liu, Qin Wang, Kun Zhang, Chunyan Zhu, Duo Wang, Guanhua Qiu, Xiaoqi Zhu, Chao Fang

“…Background Immunosuppressive tumor microenvironment (ITM) remains an obstacle that jeopardizes clinical immunotherapy.Methods To address this concern, we have engineered an exosome inherited from M1-pheototype macrophages, which thereby retain functions and ingredients of the parent M1-phenotype macrophages. …”
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Single-Cell Transcriptome Analysis Profile of Meniscal Tissue Macrophages in Human Osteoarthritis by Jingbin Zhou, Zhihong Zhao, Chen He, Feng Gao, Yu Guo, Feng Qu, Yujie Liu

“…Here, we have used single-cell RNA sequencing analysis to gain insight into the heterogeneity and functional specialization of human knee macrophages. We also compared the gene expression profiles of macrophages in healthy people and OA patients and found the characteristic changes of special macrophages in the OA knee. …”
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Tumor Cells and Tumor-Associated Macrophages: Secreted Proteins as Potential Targets for Therapy by Marc Baay, Anja Brouwer, Patrick Pauwels, Marc Peeters, Filip Lardon

“…The interaction between tumor cells and macrophages provides opportunities for therapy. This paper will discuss secreted proteins as targets for intervention.…”
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Perpetuation of inflammation associated with experimental arthritis: the role of macrophage activation by neutrophilic myeloperoxidase by Monique P. Gelderman, Rodney Stuart, David Vigerust, Steven Fuhrmann, Doris L. Lefkowitz, Robert C. Allen, Stanley S. Lefkowitz, Susan Graham

“…This study addresses a previously unrecognized interaction between neutrophilic-myeloperoxidase (MPO) and macrophages (MΦ) which could explain the perpetuation of inflammation associated with RA. …”
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Pharmacological inhibition of key metabolic pathways attenuates Leishmania spp infection in macrophages. by Elaine Carvalho de Oliveira, Rafael Tibúrcio, Gabriela Duarte, Amanda Lago, Léon de Melo, Sara Nunes, Gustavo Gastão Davanzo, Ana Júlia Martins, Bruno Vinagre Ribeiro, Deborah Mothé, Juliana B P Menezes, Patrícia Veras, Natalia Tavares, Pedro M Moraes-Vieira, Cláudia Ida Brodskyn

“…Macrophages represent a fundamental component of the innate immune system that play a critical role in detecting and responding to pathogens as well as danger signals. …”
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Metabolic and epigenetic regulation of macrophage polarization in atherosclerosis: Molecular mechanisms and targeted therapies by Pinglian Yang, Xiaoling Rong, Zhechang Gao, Jiaojiao Wang, Zhiping Liu

Subjects: “…Macrophage polarization…”
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ANKRD22 participates in the proinflammatory activities of macrophages in the colon cancer tumor microenvironment by Xiaoying Wang, Keqing Yang, Bin Yang, Rui Wang, Yongliang Zhu, Tianhui Pan

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Upregulation of TCPTP in Macrophages Is Involved in IL-35 Mediated Attenuation of Experimental Colitis by Baoren Zhang, Chenglu Sun, Yanglin Zhu, Hong Qin, Dejun Kong, Jingyi Zhang, Bo Shao, Xiang Li, Shaohua Ren, Hongda Wang, Jingpeng Hao, Hao Wang

“…The expression of TCPTP in macrophages (RAW264.7, BMDMs) and intestinal tissues after IL-35 treatment was detected. …”
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LPS Counter Regulates RNA Expression of Extracellular Proteases and Their Inhibitors in Murine Macrophages by Andreas Hald, Birgitte Rønø, Leif R. Lund, Kristoffer L. Egerod

“…Regardless of the exact situation, macrophage activation and migration are intimately connected to extracellular matrix degradation. …”
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Identification of Macrophage Genotype and Key Biological Pathways in Circulating Angiogenic Cell Transcriptome by Bert R. Everaert, Steven J. Van Laere, Robrecht Lembrechts, Vicky Y. Hoymans, Jean-Pierre Timmermans, Christiaan J. Vrints

“…The CACiv transcriptome strongly related to tissue macrophages, and more specifically to regulatory M2c macrophages. …”
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Macrophages Are Key Regulators of Stem Cells during Skeletal Muscle Regeneration and Diseases by Junio Dort, Paul Fabre, Thomas Molina, Nicolas A. Dumont

“…Among these different cell types, macrophages emerged as a central actor coordinating the different cellular interactions and biological processes. …”
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Peroxisome Proliferator-Activated Receptor-γ-Mediated Polarization of Macrophages in Leishmania Infection by Marion M. Chan, Nagasuresh Adapala, Cui Chen

“…In the disease leishmaniasis, the causative protozoan parasites are harbored inside the macrophages. Leishmania species adapt strategies to make the infection chronic, keeping a balance between their own and the host's defense so as to establish an environment that is favorable for survival and propagation. …”
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Adhered macrophages as an additional marker of cardiomyocyte injury in biopsies of patients with dilated cardiomyopathy by Warmusz Oliwia, Badziński Arkadiusz, Reichman-Warmusz Edyta, Dudek Damian, Wojnicz Romuald

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Understanding the Mysterious M2 Macrophage through Activation Markers and Effector Mechanisms by Tamás Rőszer

“…Today the M2 macrophages are identified based on the expression pattern of a set of M2 markers. …”
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Targeted SPP1 Inhibition of Tumor‐Associated Myeloid Cells Effectively Decreases Tumor Sizes by Benan Kartal, Christopher S. Garris, Hyung Shik Kim, Rainer H. Kohler, Jasmine Carrothers, Elias A. Halabi, Yoshiko Iwamoto, Anne‐Gaëlle Goubet, Yuxuan Xie, Pratyaksha Wirapati, Mikaël J. Pittet, Ralph Weissleder

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The transcriptome of MHV‐infected RAW264.7 cells offers an alternative model for macrophage innate immunity research by Yun Liu, Ting‐Ting Feng, Wei Tong, Zhi Guo, Xia Li, Qi Kong, Zhi‐Guang Xiang

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Unraveling the immunomodulatory and metabolic effects of bioactive glass S53P4 on macrophages in vitro by Karoliina Kajander, Nicole Nowak, Negin Vaziri, Pekka K. Vallittu, Terhi J. Heino, Jorma A. Määttä

“…Abstract Macrophage metabolism is closely linked to their phenotype and function, which is why there is growing interest in studying the metabolic reprogramming of macrophages. …”
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A Proinflammatory Effect of the β-Glucan from Pleurotus cornucopiae Mushroom on Macrophage Action by Ken-ichiro Minato, Akihiro Ohara, Masashi Mizuno

“…However, the PCPS did not induce to express both IL-12 and IL-10 mRNA in the macrophages. Next, the P. cornucopiae extract (containing mainly PCPS) treatment against mice showed significant increases in TNF and IL-1β mRNA expressions in the peritoneal macrophages of them. …”
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Role of Acetylsalicylic Acid in Cytokine Stimulation of Macrophages in Antibody-Dependent Cellular Cytotoxicity (ADCC) by M. Jäpel, H. Lötzerich, K. Rogalla

“…The action of ASA on the activity of mouse peritoneal macrophages was therefore investigated in the present study. …”
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