A phase-transited lysozyme coating doped with strontium on titanium surface for bone repairing via enhanced osteogenesis and immunomodulatory by Yu Zhang, Yu Chen, Yidan Shi, Hongkun Hu, Zhongyu Dai, Zhichen Liu, Xuanan Li

“…In vitro cellular experiments have demonstrated that it promotes M2 macrophage polarization and reduces inflammatory mediator production while promoting osteogenic differentiation of bone merrow mesenchymal stem cells (BMSCs). …”
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Blood molecular subtypes to guide precision treatment strategies in systemic juvenile idiopathic arthritis by In-Woon Baek, Jung Woo Rhim, Kyung-Su Park, Ki-Jo Kim

“…C1 was the most inflammatory subset with a high-risk profile for macrophage activation syndrome. The C2 subset had the most activated IL-1 and IL-18 signaling pathways. …”
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Therapeutic reduction of neurocan in murine intracerebral hemorrhage lesions promotes oligodendrogenesis and functional recovery by Hongmin Li, Samira Ghorbani, Olayinka Oladosu, Ping Zhang, Frank Visser, Jeff Dunn, Yunyan Zhang, Chang-Chun Ling, V. Wee Yong, Mengzhou Xue

“…Brain cryosections were also stained for microglia/macrophage phenotype, oligodendrocyte lineage cells and neuroblasts by immunofluorescence microscopy. …”
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Therapeutic effects of chlorogenic acid on allergic rhinitis through TLR4/MAPK/NF-κB pathway modulation by Xiaoyan Xu, Lei Wang, Guangyao Wu, Xixia Li

“…This study aimed to evaluate the therapeutic effects of CGA on inflammation in RAW264.7 macrophage cells and on AR in mice. RAW264.7 cells were treated with lipopolysaccharide (LPS) to induce inflammation and cultured with varying concentrations of CGA, a Tlr4-silenced gene (shTlr4) transfection, and the MAPK/NF-κB pathway activator diprovocim. …”
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The immune-related gene CD5 is a prognostic biomarker associated with the tumor microenvironment of breast cancer by Yi Zhao, Hengheng Zhang, Wenwen Wang, Guoshuang Shen, Miaozhou Wang, Zhen Liu, Jiuda Zhao, Jinming Li

“…TIC analysis showed that CD5 expression was positively correlated with the infiltration of CD8+ T cells, activated memory CD4+ T cells, gamma delta T cells, and M1 macrophages and negatively correlated with the infiltration of M2 macrophages. …”
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Autoimmune pulmonary alveolar proteinosis developed during treatment for systemic sclerosis: a case report by Tomoki Kozono, Kentaro Tanaka, Tomoko Yagi, Kazuto Kamikawaji, Masaki Watanabe, Azusa Iwanaga, Minako Hamada, Yoshifusa Koreeda, Hiromasa Inoue, Ikkou Higashimoto

“…Serum anti granulocyte–macrophage colony-stimulating factor (GM-CSF) antibodies were measured, and the result was positive, leading to the diagnosis of APAP. …”
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Pharmacological Inhibition of Caspase-1 Ameliorates Cisplatin-Induced Nephrotoxicity through Suppression of Apoptosis, Oxidative Stress, and Inflammation in Mice by Jung-Yeon Kim, Jae-Hyung Park, Kiryeong Kim, Jungmin Jo, Jaechan Leem, Kwan-Kyu Park

“…Moreover, increased macrophage accumulation and elevated expression of cytokines and chemokines were attenuated by caspase-1 inhibition. …”
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Effects of bronchoscopic alveolar lavage–assisted mechanical ventilation on postoperative pulmonary infection and inflammatory factors in patients undergoing lung cancer surgery by Hui Zhu, Haiyang Lu

“…The levels of inflammatory markers (high-sensitivity C-reactive protein, procalcitonin, tumor necrosis factor α, high-mobility group box 1, interleukin 6, and macrophage inflammatory protein 1α) in peripheral blood were decreased regardless of the treatment method (all P <⁠0.05). …”
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TMEM101 expression and its impact on immune cell infiltration and prognosis in hepatocellular carcinoma by Lingyun Kuang, Yilin Pang, Quangang Fang

“…The findings from CIBERSORT analysis suggest that TMEM101’s pro-tumor effect may be due to decreasing the number of anti-tumor immune cells (M1 macrophages and resting memory CD4+ T cells) and promoting M0 macrophage infiltration in the tumor microenvironment (TME). …”
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Synergic Renoprotective Effects of Combined ASC Therapy with RAAS Blockade in Experimental Advanced CKD by Marina P. C. Maires, Krislley R. Pereira, Everidiene K. V. B. Silva, Victor H. R. Souza, Flavio Teles, Paulyana F. Barbosa, Margoth R. Garnica, Felipe M. Ornellas, Irene L. Noronha, Camilla Fanelli

“…The combination of ASC and Losartan was more effective than Losartan monotherapy in reducing systolic blood pressure and glomerulosclerosis and also promoted the complete normalization of proteinuria and albuminuria, a significant reduction in renal interstitial macrophage infiltration and downregulation of renal IL-6 gene expression. …”
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Genetic diversity leads to differential inflammatory responses to cigarette smoke in mice by Md Imam Faizan, Gagandeep Kaur, Sadiya Bi Shaikh, Felix Effah, Hoshang Unwalla, Irfan Rahman

“…The study involves a comprehensive approach, including BALF cytokine analysis, evaluation of lung tissue architecture, assessment of macrophages and its associated proteins (MMP9 & MMP12) abundance. …”
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A Cornflower Extract Containing N-Feruloylserotonin Reduces Inflammation in Human Skin by Neutralizing CCL17 and CCL22 and Inhibiting COX-2 and 5-LOX by Christophe Carola, Andrew Salazar, Christin Rakers, Franck Himbert, Quoc-Tuan Do, Philippe Bernard, Joerg von Hagen

“…Thymus and Activation-Regulated Chemokine (TARC/CCL17) and Macrophage-Derived Chemokine (MDC/CCL22) are two key chemokines exerting their biological effect via binding and activating a common receptor CCR4, expressed at the surface of type 2 helper T (Th2) cells. …”
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Morphophysiological alterations caused by insertional mutagenesis of contactin 5 (Cntn5) gene in transgenic mice by A. V. Smirnov, N. A. Feofanova, G. V. Kontsevaya, M. V. Anisimova, I. I. Kovrigin, I. A. Serova, M. P. Moshkin, L. A. Gerlinskaya, N. R. Battulin

“…In this paper, we report our analysis of morphophysiological parameters of the transgenic mouse line GM9, in which a transgene designed for milk-specific expression of the human granulocyte-macrophage colony-stimulating factor (GM-CSF) gene was integrated into the intron of the Contactin 5 gene (Cntn5). …”
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From pain to meningitis: bacteria hijack nociceptors to promote meningitis by Huazhen Liu, Xingxing Kong, Yuqin Zeng, Jinyun Chen, Zhanpeng Chen, Lanlan Liu, Quan Ma, Xuhui Liu, Xuhui Liu, Shuihua Lu

“…These interactions suppress immune defenses by inhibiting macrophage activity and neutrophil recruitment, thus facilitating bacterial survival and invasion of the CNS. …”
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The effect of triple CFTR modulator therapy and azithromycin on ion channels and inflammation in cystic fibrosis by Suhad Bani Melhim, Lisa E.J. Douglas, James A. Reihill, Damian G. Downey, S. Lorraine Martin

“…Subsequent analysis by ELISA showed IL-8, IL-6, CXCL1 and granulocyte–macrophage colony-stimulating factor to be significantly reduced by treatment with ETI, but not by AZ. …”
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The Maternal Cytokine and Chemokine Profile of Naturally Conceived Gestations Is Mainly Preserved during In Vitro Fertilization and Egg Donation Pregnancies by Alicia Martínez-Varea, Begoña Pellicer, Vicente Serra, David Hervás-Marín, Alicia Martínez-Romero, José Bellver, Alfredo Perales-Marín, Antonio Pellicer

“…The main outcome measures were, firstly, to follow up plasma levels of interleukin (IL) 1beta, IL2, IL4, IL5, IL6, IL8, IL10, IL17, interferon gamma, tumor necrosis factor-alpha (TNFα), transforming growth factor-beta (TGFβ), regulated upon activation normal T-cell expressed and secreted (RANTES), stromal cell-derived factor 1 alpha (SDF1α), and decidual granulocyte-macrophage colony-stimulating factor (GM-CSF) during the three trimesters of pregnancy during the three trimesters of pregnancy; secondly, to evaluate if the cytokine and chemokine pattern of ED pregnant women differs from that of those with autologous oocytes and, thirdly, to assess if women with preeclampsia show different cytokine and chemokine profile throughout pregnancy versus women with uneventful pregnancies. …”
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The functional insight into the genetics of cardiovascular disease: results from the post-GWAS study by L. O. Bryzgalov, E. E. Korbolina, I. S. Damarov, T. I. Merkulova

“…A significant impact on binding sites of thirteen TFs including those involved in blood cells formation, hematopoiesis, macrophage function, inflammation, and vasoconstriction was found in K562 cells. 21 rSNP gene targets and 5 partners predicted by PPI were enriched for spliceosome and endocytosis KEGG pathways, endosome sorting complex and mRNA splicing REACTOME pathways. …”
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In Vitro Antiplasmodial, Cytotoxicity, and Antioxidant Activities of Lophira lanceolata (Ochnaceae): A Cameroonian Plant Commonly Used to Treat Malaria by Mounvera Abdel Azizi, Noumedem Anangmo Christelle Nadia, Yamssi Cedric, Gamago Nkadeu Guy-Armand, Ngouyamsa Nsapkain Aboubakar Sidiki, Tientcheu Noutong Jemimah Sandra, Tako Djimefo Alex Kevin, Vincent Khan Payne

“…It tested in vitro the extracts against Plasmodium falciparum 3D7 and multiresistance Dd2. Macrophage cell lines (RAW 264.7 cells) and red blood cells were used for cytotoxicity tests. …”
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Postoperative Pulmonary Hemodynamics and Systemic Inflammatory Response in Pediatric Patients Undergoing Surgery for Congenital Heart Defects by Maria Francilene S. Souza, Juliano G. Penha, Nair Y. Maeda, Filomena R. B. G. Galas, Kelly C. O. Abud, Eloisa S. Carvalho, Ana Maria Thomaz, Claudia R. P. Castro, Juliana Pereira, Antonio Augusto Lopes

“…Using logistic regression analysis, a PAP/SAPIPO>0.40 and a heightened immediate postoperative serum level of macrophage migration inhibitory factor (quartile analysis) were shown to be predictive of significant postoperative cardiopulmonary events (respective hazard ratios with 95% CIs, 5.07 (1.10–23.45), and 3.29 (1.38–7.88)). …”
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Basidiobolomycosis Simulating a Mycobacterium ulcerans Infection in a Togolese Rural Child by Bayaki Saka, Waguena Gnassingbe, Garba Mahamadou, Sefako Akakpo, Julienne Teclessou, Aurel Abilogun-Chokki, Abas Mouhari-Toure, Koussake Kombate, Palokinam Pitché

“…Histology test performed revealed hypodermic granulomatous inflammation with predominant macrophage and eosinophils. The mycological culture was not done. …”
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