Involvement of Stat1 in the Phagocytosis of M. avium by Sabrina Dominici, Giuditta Fiorella Schiavano, Mauro Magnani, Costantina Buondelmonte, Angela Gabriela Celeste, Giorgio Brandi

“…Mycobacterium avium is an intracellular pathogen preferentially infecting human macrophages where they activate the JAK/STAT1 pathway. …”
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Role of Oxidants in Interstitial Lung Diseases: Pneumoconioses, Constrictive Bronchiolitis, and Chronic Tropical Pulmonary Eosinophilia by William N. Rom

“…These etiologic agents are phagocytosed by alveolar macrophages or bronchial epithelial cells and release chemotactic factors that recruit inflammatory cells to the lung. …”
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Immune-Stimulatory and Therapeutic Activity of Tinospora cordifolia: Double-Edged Sword against Salmonellosis by Sultan Alsuhaibani, Masood A. Khan

“…The immune-stimulating potential of AETC or METC was determined by measuring the cytokine levels in the culture supernatants of treated murine J774 macrophages. Antibacterial activity of AETC or METC was determined by treating S. typhimurium-infected macrophages and BALB/C mice. …”
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ANALYSIS OF IMMUNITY IN OSTEOSARCOMA AS A BASIS FOR DEVELOPMENT FOLLOWING THERAPY by Ferdiansyah Mahyudin, Mouli Edward, Muhammad Hardian Basuki, Kadek Seta Prawira

“…Predictors which used to determine osteosarcoma from non-invasive (stage IIB) to invasive (stage III), through the ratio of macrophages-1 (M-1) which are pro-inflammatory (anti-cancer) with macrophages-2 (M-2) which have anti-inflammatory characteristic (pro cancer) is not clear yet. …”
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The role of IFN-γ/CXCL10 axis in Mycoplasma pneumonia infection by Yanxia Zou, Feng Huang, Jiying Sun, Yidan Zheng, Ge Dai, Ting Wang, Canhong Zhu, Yongdong Yan, Renzheng Wang, Zhengrong Chen

“…Moreover, numbers of macrophages, predominantly with a M1 phenotype, were significantly increased in BALFs of children of MPP. …”
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Single‐cell sequencing reveals the features of adaptive immune responses in the liver of a mouse model of dengue fever by Yizhen Yuan, Qian Chen, Zhe Li, Fangzhou Cai, Dan Li, Wei Wang

“…The reason may be that the excessive immune response in the severe group at the late stage of DENV infection induces the polarization of macrophages into M2 type, and the macrophages then inhibit T cell immunity through the TGF‐β signaling pathway. …”
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TREM2 promotes the formation of a tumor-supportive microenvironment in hepatocellular carcinoma by Hanrui Guo, Meiling Wang, Caiya Ni, Chun Yang, Chunxue Fu, Xiaoman Zhang, Xueling Chen, Xiangwei Wu, Jun Hou, Lianghai Wang

“…Methods HCC was experimentally induced in wild-type (WT) and Trem2-deficient (Trem2 −/−) mice, and clinical sample analysis and in vitro studies on macrophages were conducted. HCC cells were treated with conditioned medium from WT or Trem2 −/− macrophages, and their malignant phenotypes and underlying mechanisms were analyzed. …”
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Connexin 37 Regulates the Kv1.3 Pathway and Promotes the Development of Atherosclerosis by Minqi Liao, Lihua Chen, Jiongbin Lu, Guangzhu Liang, Yongzhao Yao, Shumin Ouyang, Yanhua Yang, Zhengwei Jian, Suxia Guo

“…Cx37 and Kv1.3 were highly expressed in macrophages of AS mice, and the expression of Kv1.3 and CCL7 decreased after Cx37 was silenced, and the proliferation of macrophages was also decreased. …”
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Unveiling the Mechanisms for Decreased Glutathione in Individuals with HIV Infection by Devin Morris, Carlos Guerra, Clare Donohue, Hyoung Oh, Melissa Khurasany, Vishwanath Venketaraman

“…We observed lower levels of intracellular GSH in macrophages from individuals with HIV compared to healthy subjects. …”
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Microenvironment Influence of a Novel Bioengineered Wound Product, APIS®: A Preliminary In Vitro Analysis of Inflammatory Marker and Growth Factor Secretion by Isaac Rodriguez, Tricia Conti, Nina Bionda

“…This decreased the overall MMP-9/TIMP-1 ratio secreted from macrophages seeded on the BWP compared to the controls. …”
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The Controversial Role of Microglia in Malignant Gliomas by Jun Wei, Konrad Gabrusiewicz, Amy Heimberger

“…Malignant gliomas contain stroma and a variety of immune cells including abundant activated microglia/macrophages. Mounting evidence indicates that the glioma microenvironment converts the glioma-associated microglia/macrophages (GAMs) into glioma-supportive, immunosuppressive cells; however, GAMs can retain intrinsic anti-tumor properties. …”
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LR12 Promotes Liver Repair by Improving the Resolution of Inflammation and Liver Regeneration in Mice with Thioacetamide- (TAA-) Induced Acute Liver Failure by Yongjuan Wang, Xiaoli Xie, Hongqun Liu, Huimin Liu, Huiqing Jiang

“…In vitro, the supernatant from TAA+LR12-treated macrophages promoted the proliferation of LO2 cells. …”
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Force-bearing phagocytic adhesion rings mediate the phagocytosis of surface-bound particles by Subhankar Kundu, Kaushik Pal, Arghajit Pyne, Xuefeng Wang

“…It remains elusive how macrophages detach these surface-bound particles during phagocytosis. …”
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Palovarotene Can Attenuate Heterotopic Ossification Induced by Tendon Stem Cells by Downregulating the Synergistic Effects of Smad and NF-κB Signaling Pathway following Stimulation... by Junchao Huang, Jialiang Lin, Congbin Li, Bo Tang, Haijun Xiao

“…The inflammatory microenvironment dominated by macrophages also plays an important role in the course of HO. …”
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Single cell transcriptomics in blood of patients with chronic obstructive pulmonary disease by Yeonjeong Heo, Jeeyoung Kim, Seok-Ho Hong, Woo Jin Kim

“…Conclusions Using scRNA-seq, we found differences in cell type distribution, especially in monocyte/ macrophages. Several upregulated and downregulated genes were found in the monocyte/macrophages of the COPD group.…”
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The Expression and Clinical Significance of Different Forms of Mer Receptor Tyrosine Kinase in Systemic Lupus Erythematosus by Huaqun Zhu, Xiaolin Sun, Lei Zhu, Fanlei Hu, Lianjie Shi, Zhanguo Li, Yin Su

“…To investigate the expression and clinical significance of trans-membrane MerTK (mMer) on circulating CD14+ monocytes/macrophages and soluble MerTK (sMer) levels in plasma in systemic lupus erythematosus (SLE). …”
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A Role for Peroxisome Proliferator-Activated Receptors in the Immunopathology of Schistosomiasis? by Barrie J. Anthony, Jeremy T. Allen, Yuesheng S. Li, Donald P. McManus

“…In general, they are anti-inflammatory and promote Th2 type responses, and they are associated with the alternative activation of macrophages. Interestingly, helminth infections, such as the schistosome blood flukes that cause schistosomiasis, are characterised by a Th2 response and the accumulation of alternative activated macrophages. …”
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SDZ MRL 953, A Novel Synthetic Lipid a Analogue, Induces Tolerance to the Lethal Effects of Endotoxin and Enhances Nonspecific Immunity by Charles Lam, Eberhard Schütze, Emmanuel Quakyi, Ekke Liehl, Peter Stütz

“…It was found that macrophages from endotoxin-tolerant mice produced only a fraction of the TNF released by cells from control groups in response to LPS. …”
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sNASP Mutation Aggravates to the TLR4-Mediated Inflammation in SLE by TAK1 Pathway by Yatao Bao, Meng Lian, Yong Chen, Xiaotian Gu, Kunyu Cao, Xiaoping Du, Jiyu Ju

“…Here, we stimulated mouse peritoneal macrophages with different concentrations of lipopolysaccharide. …”
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Upregulating Nonneuronal Cholinergic Activity Decreases TNF Release from Lipopolysaccharide-Stimulated RAW264.7 Cells by Yi Lv, Sen Hu, Jiangyang Lu, Ning Dong, Qian Liu, Minghua Du, Huiping Zhang

“…Therefore, we explored whether LPS continuous stimulation could upregulate the nonneuronal cholinergic activity in macrophages and whether increasing autocrine ACh could decrease TNF release from the macrophages. …”
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