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861
Microglia Play a Major Role in Direct Viral-Induced Demyelination
Published 2013-01-01“…Microglia are the resident macrophage-like populations in the central nervous system (CNS). …”
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862
Change in Ocular Surface Staining during Eyelid Warming Is Related to Tear Cytokine Levels
Published 2022-01-01“…Decreasing concentrations of granulocyte macrophage colony-stimulating factor (GM-CSF, mean effect −2.98, p=0.024), IL-8 (IL-8/CXCL8, mean effect −1.35, p=0.026), and macrophage migration inhibitory factor (MIF, mean effect −2.44, p=0.033) were related to increasing OSS. …”
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863
The Actin-Bundling Protein L-Plastin: A Critical Regulator of Immune Cell Function
Published 2012-01-01“…L-plastin has been identified as an important component in cellular processes critical for neutrophil, macrophage, osteoclast, eosinophil, and T- and B-lymphocyte biology. …”
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864
Myeloid ACAT1/SOAT1: a novel regulator of dyslipidemia and retinal neovascularization
Published 2025-01-01“…We show that OIR-induced activation of macrophage/microglial cells, retinal inflammation, and pathological RNV are mediated by increases in cholesterol ester (CE) formation due to activation of the acyl-CoA: Cholesterol Acyltransferase 1/Sterol O-Acyltransferase 1 (ACAT1/SOAT1) enzyme.…”
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865
Lactobacillus gasseri LGV03-derived indole-3-lactic acid ameliorates immune response by activating aryl hydrocarbon receptor
Published 2025-01-01“…To better understand the interaction between female genital tract microbiome and immune function, the immunomodulatory activities of L. gasseri LGV03 were investigated in zebrafish models of neutropenia, macrophage and T cells deficiency. L. gasseri LGV03 showed higher potent activities in ameliorating vinorelbine-induced neutropenia, macrophage and T cells deficiency, and significantly enhanced mRNA expressions of cytokines TNF-α, TNF-β and IFN-α. …”
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866
Effects of the Glutamine Administration on T Helper Cell Regulation and Inflammatory Response in Obese Mice Complicated with Polymicrobial Sepsis
Published 2020-01-01“…Also, expressions of inflammatory cytokines and macrophage infiltration markers in adipose tissues and lungs were elevated. …”
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867
Preventive Effect of Salicylate and Pyridoxamine on Diabetic Nephropathy
Published 2016-01-01“…Salicylate showed beneficial effects on diabetic nephropathy similar to those of pyridoxamine, which include lowering blood glucose levels and inhibiting macrophage infiltration into the kidneys. Attenuation of macrophage infiltration into the kidneys and upregulation of antiglycating enzyme glyoxalase 1 gene expression were found only in the salicylate treatment group. …”
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868
Antiallodynic Effects of Cannabinoid Receptor 2 (CB2R) Agonists on Retrovirus Infection-Induced Neuropathic Pain
Published 2019-01-01“…Multicolor flow cytometry was used to determine the effects of CB2R agonists on macrophage activation and T-lymphocyte infiltration into dorsal root ganglia (DRG) and lumbar spinal cord (LSC). …”
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869
Targeting OAS3 for reversing M2d infiltration and restoring anti-tumor immunity in pancreatic cancer
Published 2024-12-01“…Abstract Abundant infiltration of tumor-associated macrophages (TAMs) within the tumor stroma plays a pivotal role in inducing immune escape in pancreatic cancer (PC). …”
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870
Cytokines and Water Distribution in Anorexia Nervosa
Published 2021-01-01“…Following blood collection, 27 cytokines and chemokines were quantified using multiplex ELISA-based technology: Eotaxin, Eotaxin-3, granulocyte-macrophage colony-stimulating factor (GM-CSF), interferon- (IFN-) γ, interleukin- (IL-) 1α, IL-1β, IL-2, IL-4, IL-5, IL-6, IL-7, IL-8, IL-10, IL-12/IL-23p40, IL-12p70, IL-13, IL-15, IL-16, IL-17A, interferon γ-induced protein- (IP-) 10, macrophage inflammatory protein- (MIP-) 1α, MIP-1β, monocyte chemoattractant protein- (MCP-) 1, MCP-4, thymus and activation-regulated chemokine (TARC), TNF-α, and TNF-β. …”
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871
Chemokine Profiles Are Affected in Serum of Patients with Acute Rejection of Kidney Allograft
Published 2021-01-01“…On the other hand, adding of monocytes/macrophages to a culture of renal epithelial cells suppressed the release of CXCL10 and CXCL11 attracting T lymphocytes. …”
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872
Alterations in Adipose Tissue and Adipokines in Heterozygous APE1/Ref-1 Deficient Mice
Published 2024-12-01“…Histological and immunohistochemical analyses revealed hypertrophic adipocytes and macrophage infiltration in WAT, while Oil Red O staining demonstrated enhanced ectopic fat deposition in the liver of APE1/Ref-1+/- mice. …”
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873
ICAM1 blockade improves ischemic muscle reperfusion in diabetic mice
Published 2025-01-01“…This was associated with an increased macrophage infiltration and an impaired myocyte differentiation. …”
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874
The Role of TAMs in Tumor Microenvironment and New Research Progress
Published 2022-01-01“…Tumor-associated macrophages (TAMs) are an important part of tumor microenvironment (TME) and play a key role in TME, participating in the process of tumor occurrence, growth, invasion, and metastasis. …”
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875
Pivotal Roles of GM-CSF in Autoimmunity and Inflammation
Published 2015-01-01“…Granulocyte macrophage-colony stimulating factor (GM-CSF) is a hematopoietic growth factor, which stimulates the proliferation of granulocytes and macrophages from bone marrow precursor cells. …”
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876
集落刺激因子促进豚鼠体内造血的研究
Published 1991-01-01“…给11只Harty豚鼠腹腔内注射胎盘条件培养液(HPCM)0.5ml/d,共10天,周围血白细胞总数明显升高,以中性粒细胞升高为主.6只BALB/C小鼠腹腔内注射HPCMOo.3ml/d,共7天,粒-巨噬祖细胞(granulocy-macrophage colng-formung unit,CFU-GM)产率明显升高,是对照组给的2.l倍.结果提示,胎盘条件培养液来源的集落刺激因子,在体内能促进CFU-GM增殖,担升周围血白细胞和中性粒细胞.…”
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877
The Role of MIF in Type 1 and Type 2 Diabetes Mellitus
Published 2014-01-01“…Both processes are orchestrated by inflammatory cytokines, including the macrophage migration inhibitory factor (MIF). To date, MIF has been implicated in both types of diabetes; therefore, understanding the role of MIF could affect our understanding of the autoimmune or inflammatory responses that influence diabetic pathology. …”
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878
Concurrent Pulmonary and Cerebellar Cryptococcus Gattii Cryptococcoma in an Apparently Immunocompetent Patient in Florida
Published 2021-01-01“…Recently, antigranulocyte-macrophage colony-stimulating (GM-CSF) antibodies have been identified as a risk factor for cryptococcosis. …”
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879
Role of T Lymphocytes in Type 2 Diabetes and Diabetes-Associated Inflammation
Published 2017-01-01“…Inflammatory regulation has been focused on innate immunity especially macrophage for a long time, while increasing evidence suggests T cells are crucial for the development of metabolic inflammation and insulin resistance since 2009. …”
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880
Intercellular TIMP-1-CD63 signaling directs the evolution of immune escape and metastasis in KRAS-mutated pancreatic cancer cells
Published 2025-01-01“…Digital spatial profiling analysis of PDAC samples demonstrates the colocalization of TIMP-1high macrophages and CD63high cancer cells. The presence of TIMP-1high macrophages and CD63high epithelial cells correlates with poor prognosis in PDAC. …”
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