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FXR activation reduces the formation of macrophage foam cells and atherosclerotic plaque, possibly by down regulating hepatic lipase in macrophages
Published 2025-02-01Subjects: Get full text
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Macrophage Migration Inhibitory Factor in Protozoan Infections
Published 2012-01-01“…Macrophage migration inhibitory factor (MIF) is a cytokine that plays a central role in immune and inflammatory responses. …”
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Macrophage-mimicking nanotherapy for attenuation of acute pancreatitis
Published 2025-02-01Subjects: Get full text
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24
Autophagy in Macrophages: Impacting Inflammation and Bacterial Infection
Published 2014-01-01“…This review focuses on the intimately linked molecular mechanisms that help govern the autophagic pathway and macrophage innate immune responses.…”
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Dysregulated Functions of Lung Macrophage Populations in COPD
Published 2018-01-01“…In addition, we discuss the differences in the responses between alveolar macrophages and interstitial macrophages/monocytes in the disease and propose how the field should advance to better understand the implications of lung macrophage functions in COPD.…”
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Tumor-Associated Macrophages and Neutrophils in Tumor Microenvironment
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Macrophage Activities in Myocardial Infarction and Heart Failure
Published 2020-01-01“…Long ago, it was thought that macrophages are of importance in the heart after MI. …”
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28
The Role of Macrophages in the Pathogenesis of Inflammatory Bowel Disease
Published 1993-01-01Get full text
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Macrophage-Derived Biomarkers of Idiopathic Pulmonary Fibrosis
Published 2011-01-01“…Cytokines, CC-chemokines, and other macrophage-produced mediators are the most promising prognostic biomarkers. …”
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Modulation of nitric oxide synthase activity in macrophages
Published 1995-01-01“…Other cytokines can modulate the induction of NO biosynthesis in macrophages. NO is a major effector molecule of the anti-microbial and cytotoxic activity of rodent macrophages against certain micro-organisms and tumour cells, respectively. …”
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Monocyte-Derived Macrophages Are Impaired in Myelodysplastic Syndrome
Published 2016-01-01“…We analyzed the role of macrophages from MDS patients in vitro. Methods. Macrophages were induced from peripheral blood of patients with MDS via granulocyte macrophage colony-stimulating factor (GM-CSF). …”
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Increased cardiac macrophages in Sorbs2-deficient hearts: revealing a potential role for macrophage in responding to embryonic myocardial abnormalities
Published 2025-01-01Subjects: “…macrophage…”
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Comparison of human-induced pluripotent stem cell-derived macrophages with peripheral blood-derived macrophages using single-cell genomics
Published 2024-12-01Subjects: Get full text
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Activation of Macrophages by Oligomeric Proteins of Different Size and Origin
Published 2018-01-01“…Activation of macrophages is one of the key processes in generating the immune response against pathogens or misfolded/aggregated otherwise unharmful host’s proteins. …”
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Effect of Antifungal-Treated Host Macrophages on Candida glabrata
Published 2021-01-01“…Cytokines from infected macrophage supernatants and the levels of superoxide dismutase (SOD) in macrophages were measured at different time points after phagocytosis. …”
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TNF Tolerance in Monocytes and Macrophages: Characteristics and Molecular Mechanisms
Published 2017-01-01“…Tumor necrosis factor (TNF) tolerance in monocytes and macrophages means that preexposure to TNF reduces the sensitivity in these cells to a subsequent restimulation with this cytokine. …”
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Macrophage Polarization in Cerebral Aneurysm: Perspectives and Potential Targets
Published 2017-01-01“…We provide a concise overview of the mechanisms associated with macrophage plasticity and the emerging molecular targets.…”
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Macrophage Plasticity and the Role of Inflammation in Skeletal Muscle Repair
Published 2013-01-01“…Recent findings have uncovered a central role for macrophages in the repair of skeletal muscle after acute damage. …”
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The Metabolic Features of Tumor-Associated Macrophages: Opportunities for Immunotherapy?
Published 2021-01-01“…Besides transformed cells, the tumors are composed of various cell types that contribute to undesirable tumor progression. Tumor-associated macrophages (TAMs) are the most abundant innate immune cells in the tumor microenvironment (TME). …”
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